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C-Type Lectins in Veterinary Species: Recent Advancements and Applications

Immunology Unit & Research Center for Emerging Infections and Zoonoses (RIZ), University for Veterinary Medicine Hannover, Foundation, 30559 Hannover, Germany
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Int. J. Mol. Sci. 2020, 21(14), 5122; https://doi.org/10.3390/ijms21145122
Received: 29 June 2020 / Revised: 16 July 2020 / Accepted: 17 July 2020 / Published: 20 July 2020
(This article belongs to the Special Issue Glycosylation-Based Biomarkers in Diseases and Drug Delivery)
C-type lectins (CTLs), a superfamily of glycan-binding receptors, play a pivotal role in the host defense against pathogens and the maintenance of immune homeostasis of higher animals and humans. CTLs in innate immunity serve as pattern recognition receptors and often bind to glycan structures in damage- and pathogen-associated molecular patterns. While CTLs are found throughout the whole animal kingdom, their ligand specificities and downstream signaling have mainly been studied in humans and in model organisms such as mice. In this review, recent advancements in CTL research in veterinary species as well as potential applications of CTL targeting in veterinary medicine are outlined. View Full-Text
Keywords: C-type lectin; glycans; immune modulation; comparative immunology; veterinary immunology C-type lectin; glycans; immune modulation; comparative immunology; veterinary immunology
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MDPI and ACS Style

Lindenwald, D.L.; Lepenies, B. C-Type Lectins in Veterinary Species: Recent Advancements and Applications. Int. J. Mol. Sci. 2020, 21, 5122. https://doi.org/10.3390/ijms21145122

AMA Style

Lindenwald DL, Lepenies B. C-Type Lectins in Veterinary Species: Recent Advancements and Applications. International Journal of Molecular Sciences. 2020; 21(14):5122. https://doi.org/10.3390/ijms21145122

Chicago/Turabian Style

Lindenwald, Dimitri L.; Lepenies, Bernd. 2020. "C-Type Lectins in Veterinary Species: Recent Advancements and Applications" Int. J. Mol. Sci. 21, no. 14: 5122. https://doi.org/10.3390/ijms21145122

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