Next Article in Journal
A Yeast-Based Model for Hereditary Motor and Sensory Neuropathies: A Simple System for Complex, Heterogeneous Diseases
Next Article in Special Issue
Transcriptional Regulators and Human-Specific/Primate-Specific Genes in Neocortical Neurogenesis
Previous Article in Journal
Therapeutic Potential of Tauroursodeoxycholic Acid for the Treatment of Osteoporosis
Previous Article in Special Issue
Molecular Regulation in Dopaminergic Neuron Development. Cues to Unveil Molecular Pathogenesis and Pharmacological Targets of Neurodegeneration

Neuronal Reprogramming for Tissue Repair and Neuroregeneration

Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, Melbourne, VIC 3002, Australia
Ophthalmology, Department of Surgery, University of Melbourne, Melbourne, VIC 3002, Australia
John van Geest Centre for Brain Repair, University of Cambridge, Cambridge CB2 0PY, UK
Author to whom correspondence should be addressed.
Int. J. Mol. Sci. 2020, 21(12), 4273;
Received: 8 May 2020 / Revised: 8 June 2020 / Accepted: 8 June 2020 / Published: 16 June 2020
(This article belongs to the Special Issue Role of Gene Expression in the Physiology and Pathology of Neurons)
Stem cell and cell reprogramming technology represent a rapidly growing field in regenerative medicine. A number of novel neural reprogramming methods have been established, using pluripotent stem cells (PSCs) or direct reprogramming, to efficiently derive specific neuronal cell types for therapeutic applications. Both in vitro and in vivo cellular reprogramming provide diverse therapeutic pathways for modeling neurological diseases and injury repair. In particular, the retina has emerged as a promising target for clinical application of regenerative medicine. Herein, we review the potential of neuronal reprogramming to develop regenerative strategy, with a particular focus on treating retinal degenerative diseases and discuss future directions and challenges in the field. View Full-Text
Keywords: cell reprogramming; pluripotent stem cells; retina; neuroregeneration cell reprogramming; pluripotent stem cells; retina; neuroregeneration
MDPI and ACS Style

Liou, R.H.-C.; Edwards, T.L.; Martin, K.R.; Wong, R.C.-B. Neuronal Reprogramming for Tissue Repair and Neuroregeneration. Int. J. Mol. Sci. 2020, 21, 4273.

AMA Style

Liou RH-C, Edwards TL, Martin KR, Wong RC-B. Neuronal Reprogramming for Tissue Repair and Neuroregeneration. International Journal of Molecular Sciences. 2020; 21(12):4273.

Chicago/Turabian Style

Liou, Roxanne H.-C.; Edwards, Thomas L.; Martin, Keith R.; Wong, Raymond C.-B. 2020. "Neuronal Reprogramming for Tissue Repair and Neuroregeneration" Int. J. Mol. Sci. 21, no. 12: 4273.

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

Search more from Scilit
Back to TopTop