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The Role of Curcumin in the Modulation of Ageing

Nencki Institute of Experimental Biology, Polish Academy of Sciences, 3 Pasteur St., 02-093 Warsaw, Poland
Authors to whom correspondence should be addressed.
Int. J. Mol. Sci. 2019, 20(5), 1239;
Received: 6 February 2019 / Revised: 4 March 2019 / Accepted: 6 March 2019 / Published: 12 March 2019
(This article belongs to the Special Issue Curcumin in Health and Disease)
It is believed that postponing ageing is more effective and less expensive than the treatment of particular age-related diseases. Compounds which could delay symptoms of ageing, especially natural products present in a daily diet, are intensively studied. One of them is curcumin. It causes the elongation of the lifespan of model organisms, alleviates ageing symptoms and postpones the progression of age-related diseases in which cellular senescence is directly involved. It has been demonstrated that the elimination of senescent cells significantly improves the quality of life of mice. There is a continuous search for compounds, named senolytic drugs, that selectively eliminate senescent cells from organisms. In this paper, we endeavor to review the current knowledge about the anti-ageing role of curcumin and discuss its senolytic potential. View Full-Text
Keywords: ageing; anti-cancer; autophagy; microbiota; senescence; senolytics ageing; anti-cancer; autophagy; microbiota; senescence; senolytics
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MDPI and ACS Style

Bielak-Zmijewska, A.; Grabowska, W.; Ciolko, A.; Bojko, A.; Mosieniak, G.; Bijoch, Ł.; Sikora, E. The Role of Curcumin in the Modulation of Ageing. Int. J. Mol. Sci. 2019, 20, 1239.

AMA Style

Bielak-Zmijewska A, Grabowska W, Ciolko A, Bojko A, Mosieniak G, Bijoch Ł, Sikora E. The Role of Curcumin in the Modulation of Ageing. International Journal of Molecular Sciences. 2019; 20(5):1239.

Chicago/Turabian Style

Bielak-Zmijewska, Anna, Wioleta Grabowska, Agata Ciolko, Agnieszka Bojko, Grażyna Mosieniak, Łukasz Bijoch, and Ewa Sikora. 2019. "The Role of Curcumin in the Modulation of Ageing" International Journal of Molecular Sciences 20, no. 5: 1239.

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