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Open AccessEditorial

Editorial of Special Issue “Surface-Functionalized Nanoparticles as Drug Carriers”

Department of Pharmaceutics, College of Pharmacy, University of Minnesota, Minneapolis, MN 55455, USA
Department of Pharmaceutical Sciences, College of Health Professions, North Dakota State University, Fargo, ND 58108-6050, USA
Authors to whom correspondence should be addressed.
Int. J. Mol. Sci. 2019, 20(24), 6352;
Received: 11 December 2019 / Accepted: 13 December 2019 / Published: 17 December 2019
(This article belongs to the Special Issue Surface-Functionalized Nanoparticles as Drug Carriers)
Safe and effective delivery of therapeutics at the target site is the key to successful therapy. Nanocarriers can offer significant advantages over conventional dosage forms. Over the decades, nanoparticles have been extensively used to increase bioavailability, improve solubility and stability, reduce toxicities, and facilitate the controlled release of therapeutics. Further, nanoparticles have often been surface-functionalized with a variety of ligands to enhance circulation half-life and increase target-specificity. Although nanotechnology has shown significant therapeutic benefits for multiple biomedical applications, limited nanoparticle-based formulations have progressed to clinical trials, and only a few have reached the pharmaceutical market. This editorial is an introduction to the special issue entitled Surface-Functionalized Nanoparticles as Drug Carriers. We outline the scope of the special issue, summarize the results and conclusions of the nine articles published in this issue, and provide perspective on the application of surface-functionalized nanoparticles in the drug delivery field. View Full-Text
Keywords: drug delivery; nanoparticles; surface-functionalized nanoparticles; bioavailability; controlled release drug delivery; nanoparticles; surface-functionalized nanoparticles; bioavailability; controlled release
MDPI and ACS Style

Layek, B.; Singh, J. Editorial of Special Issue “Surface-Functionalized Nanoparticles as Drug Carriers”. Int. J. Mol. Sci. 2019, 20, 6352.

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