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Review

Unique Features of Entamoeba Sulfur Metabolism; Compartmentalization, Physiological Roles of Terminal Products, Evolution and Pharmaceutical Exploitation

Division of Molecular and Cellular Immunoscience, Department of Biomolecular Sciences, Faculty of Medicine, Saga University, 5-1-1 Nabeshima, Saga 849-8501, Japan
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Int. J. Mol. Sci. 2019, 20(19), 4679; https://doi.org/10.3390/ijms20194679
Received: 30 August 2019 / Revised: 18 September 2019 / Accepted: 19 September 2019 / Published: 21 September 2019
(This article belongs to the Collection Feature Papers in Molecular Microbiology)
Sulfur metabolism is essential for all living organisms. Recently, unique features of the Entamoeba metabolic pathway for sulfated biomolecules have been described. Entamoeba is a genus in the phylum Amoebozoa and includes the causative agent for amoebiasis, a global public health problem. This review gives an overview of the general features of the synthesis and degradation of sulfated biomolecules, and then highlights the characteristics that are unique to Entamoeba. Future biological and pharmaceutical perspectives are also discussed. View Full-Text
Keywords: amoebiasis; mitosome; lipid metabolism; encystation; lateral gene transfer amoebiasis; mitosome; lipid metabolism; encystation; lateral gene transfer
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MDPI and ACS Style

Mi-ichi, F.; Yoshida, H. Unique Features of Entamoeba Sulfur Metabolism; Compartmentalization, Physiological Roles of Terminal Products, Evolution and Pharmaceutical Exploitation. Int. J. Mol. Sci. 2019, 20, 4679. https://doi.org/10.3390/ijms20194679

AMA Style

Mi-ichi F, Yoshida H. Unique Features of Entamoeba Sulfur Metabolism; Compartmentalization, Physiological Roles of Terminal Products, Evolution and Pharmaceutical Exploitation. International Journal of Molecular Sciences. 2019; 20(19):4679. https://doi.org/10.3390/ijms20194679

Chicago/Turabian Style

Mi-ichi, Fumika, and Hiroki Yoshida. 2019. "Unique Features of Entamoeba Sulfur Metabolism; Compartmentalization, Physiological Roles of Terminal Products, Evolution and Pharmaceutical Exploitation" International Journal of Molecular Sciences 20, no. 19: 4679. https://doi.org/10.3390/ijms20194679

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