Endocannabinoid System in Hepatic Glucose Metabolism, Fatty Liver Disease, and Cirrhosis
Abstract
:1. Introduction
2. Expression of Cannabinoid Receptors CB1 and CB2
2.1. Diurnal Expression of Hepatic Cannabinoid Receptors CB1 and CB2
2.2. Cannabinoid Receptor CB1- and CB2-Function and Its Metabolic Consequences in the Liver
2.3. Cannabinoid Receptor CB1- and CB2-Agonism/Antagonism in Metabolic Disorders of the Liver
3. Other Hepatic Cannabinoid Receptors in Metabolism and Metabolic Disorders of the Liver
3.1. G Protein-Coupled Receptor 55 (GPR55)
3.2. G Protein-Coupled Receptor (GPR119)
4. Peroxisome Proliferator-Activated Receptors (PPARs)
4.1. PPARα
4.2. PPARβ/δ
4.3. PPARγ
5. Endocannabinoid System and Liver Cirrhosis
5.1. Endocannabinoids AEA, 2-AG, and PEA
5.2. CB1- and CB2-Receptor
5.3. Endocannabinoids and Hemodynamics in Cirrhosis
6. Summary and Conclusions
Author Contributions
Funding
Acknowledgments
Conflicts of Interest
References
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Bazwinsky-Wutschke, I.; Zipprich, A.; Dehghani, F. Endocannabinoid System in Hepatic Glucose Metabolism, Fatty Liver Disease, and Cirrhosis. Int. J. Mol. Sci. 2019, 20, 2516. https://doi.org/10.3390/ijms20102516
Bazwinsky-Wutschke I, Zipprich A, Dehghani F. Endocannabinoid System in Hepatic Glucose Metabolism, Fatty Liver Disease, and Cirrhosis. International Journal of Molecular Sciences. 2019; 20(10):2516. https://doi.org/10.3390/ijms20102516
Chicago/Turabian StyleBazwinsky-Wutschke, Ivonne, Alexander Zipprich, and Faramarz Dehghani. 2019. "Endocannabinoid System in Hepatic Glucose Metabolism, Fatty Liver Disease, and Cirrhosis" International Journal of Molecular Sciences 20, no. 10: 2516. https://doi.org/10.3390/ijms20102516