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Int. J. Mol. Sci. 2017, 18(5), 1075;

hCG Triggering in ART: An Evolutionary Concept

Department of Obstetrics and Gynecology, Meir Medical Center, Kfar Saba 4428164, Israel
The Sackler School of Medicine, Tel Aviv University, Tel Aviv-Yafo 6997801, Israel
Author to whom correspondence should be addressed.
Academic Editor: Udo Jeschke
Received: 26 February 2017 / Revised: 28 April 2017 / Accepted: 6 May 2017 / Published: 17 May 2017
(This article belongs to the Special Issue hCG—An Endocrine, Regulator of Gestation and Cancer)
Full-Text   |   PDF [174 KB, uploaded 17 May 2017]


Human chorionic gonadotropin (hCG) is no longer a single, omnipotent ovulation triggering option. Gonadotropin releasing hormone (GnRH) agonist, initially presented as a substitute for hCG, has led to a new era of administering GnRH agonist followed by hCG triggering. According to this new concept, GnRH agonist enables successful ovum maturation, while hCG supports the luteal phase and pregnancy until placental shift. View Full-Text
Keywords: chorionic gonadotropin; LH receptor; ovulation induction; ovarian stimulation chorionic gonadotropin; LH receptor; ovulation induction; ovarian stimulation
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Hershko Klement, A.; Shulman, A. hCG Triggering in ART: An Evolutionary Concept. Int. J. Mol. Sci. 2017, 18, 1075.

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