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Int. J. Mol. Sci. 2017, 18(12), 2392;

Analgesic-Like Activity of Essential Oil Constituents: An Update

Departamento de Fisiologia e Patologia, Universidade Federal da Paraíba, CP 5009, João Pessoa-PB 58051-970, Brazil
Departamento de Farmácia, Universidade Federal de Sergipe, São Cristóvão-SE 49100-000, Brazil
Departamento de Ciências Farmacêuticas, Universidade Federal da Paraíba, João Pessoa-PB 58051-970, Brazil
Author to whom correspondence should be addressed.
Received: 23 October 2017 / Revised: 3 November 2017 / Accepted: 3 November 2017 / Published: 9 December 2017
(This article belongs to the Special Issue Effective Mechanisms of Plant Bioactive Essential Fats and Oils)
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The constituents of essential oils are widely found in foods and aromatic plants giving characteristic odor and flavor. However, pharmacological studies evidence its therapeutic potential for the treatment of several diseases and promising use as compounds with analgesic-like action. Considering that pain affects a significant part of the world population and the need for the development of new analgesics, this review reports on the current studies of essential oils’ chemical constituents with analgesic-like activity, including a description of their mechanisms of action and chemical aspects. View Full-Text
Keywords: analgesic; antinociceptive; terpenes; phenylpropanoid; natural products; medicinal plants; aromas; flavor; volatile; food analgesic; antinociceptive; terpenes; phenylpropanoid; natural products; medicinal plants; aromas; flavor; volatile; food
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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De Cássia da Silveira e Sá, R.; Lima, T.C.; Da Nóbrega, F.R.; De Brito, A.E.M.; De Sousa, D.P. Analgesic-Like Activity of Essential Oil Constituents: An Update. Int. J. Mol. Sci. 2017, 18, 2392.

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