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Int. J. Mol. Sci. 2015, 16(7), 15188-15193;

More Adventures in Photodynamic Therapy

Department of Pharmacology, Wayne State University School of Medicine, 540 E Canfield Street, Detroit, MI 48201, USA
Academic Editor: Michael R. Hamblin
Received: 14 May 2015 / Revised: 23 June 2015 / Accepted: 23 June 2015 / Published: 3 July 2015
(This article belongs to the Special Issue Advances in Photodynamic Therapy)
Full-Text   |   PDF [613 KB, uploaded 3 July 2015]


Photodynamic therapy is a procedure that can provide a selective eradication of neoplastic disease if sufficient drug, light, and oxygen are available. As this description suggests, it involves the photosensitization of malignant tissues to irradiation with photons in the visible range. While not suitable for tumors at unknown loci, it can be of use for eradication of cancer at surgical margins and therapy at sites where substantial surgery might otherwise be involved. Drug development has been delayed by several factors including the reluctance of major pharmaceutical firms in the United States to invest in this technology along with some unwise approaches in the past. View Full-Text
Keywords: apoptosis; autophagy; photodynamic therapy apoptosis; autophagy; photodynamic therapy
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Kessel, D. More Adventures in Photodynamic Therapy. Int. J. Mol. Sci. 2015, 16, 15188-15193.

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