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Open AccessReview

Recent Advances in Proteomic Studies of Adipose Tissues and Adipocytes

by Eun Young Kim 1,†, Won Kon Kim 1,2,†, Kyoung-Jin Oh 1, Baek Soo Han 1,2, Sang Chul Lee 1,2,* and Kwang-Hee Bae 1,2,*
1
Functional Genomics Research Center, KRIBB, Daejeon 305-806, Korea
2
Department of Functional Genomics, University of Science and Technology of Korea, Daejeon 305-806, Korea
*
Authors to whom correspondence should be addressed.
These authors contributed equally to this work.
Academic Editor: Ritva Tikkanen
Int. J. Mol. Sci. 2015, 16(3), 4581-4599; https://doi.org/10.3390/ijms16034581
Received: 5 December 2014 / Revised: 29 December 2014 / Accepted: 16 February 2015 / Published: 27 February 2015
(This article belongs to the Collection Advances in Proteomic Research)
Obesity is a chronic disease that is associated with significantly increased levels of risk of a number of metabolic disorders. Despite these enhanced health risks, the worldwide prevalence of obesity has increased dramatically over the past few decades. Obesity is caused by the accumulation of an abnormal amount of body fat in adipose tissue, which is composed mostly of adipocytes. Thus, a deeper understanding of the regulation mechanism of adipose tissue and/or adipocytes can provide a clue for overcoming obesity-related metabolic diseases. In this review, we describe recent advances in the study of adipose tissue and/or adipocytes, focusing on proteomic approaches. In addition, we suggest future research directions for proteomic studies which may lead to novel treatments of obesity and obesity-related diseases. View Full-Text
Keywords: adipocytes; adipogenesis; adipose tissue; browning; proteomics adipocytes; adipogenesis; adipose tissue; browning; proteomics
MDPI and ACS Style

Kim, E.Y.; Kim, W.K.; Oh, K.-J.; Han, B.S.; Lee, S.C.; Bae, K.-H. Recent Advances in Proteomic Studies of Adipose Tissues and Adipocytes. Int. J. Mol. Sci. 2015, 16, 4581-4599.

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