Next Article in Journal
High Cytoplasmic Expression of Krüppel-like Factor 4 Is an Independent Prognostic Factor of Better Survival in Hepatocellular Carcinoma
Next Article in Special Issue
MicroRNAs in Brain Metastases: Potential Role as Diagnostics and Therapeutics
Previous Article in Journal
Ginsenoside Rd Attenuates Mitochondrial Permeability Transition and Cytochrome c Release in Isolated Spinal Cord Mitochondria: Involvement of Kinase-Mediated Pathways
Previous Article in Special Issue
Gamma Knife Treatment of Brainstem Metastases
Open AccessReview

SPECT and PET Serve as Molecular Imaging Techniques and in Vivo Biomarkers for Brain Metastases

1
Section of Nuclear Medicine and Health Physics, Department of Surgical and Biomedical Sciences, University of Perugia, Perugia 06100, Italy
2
Section of Nuclear Medicine, Department of Clinical and Experimental Medicine, University of Sassari, Sassari 07100, Italy
3
Department of Biomedicine and Prevention, University of Rome Tor Vergata, Roma 00133, Italy
4
IRCCS Neuromed Pozzilli, Pozzilli (Isernia) 86077, Italy
5
Department of Engineering, University of Perugia, Perugia 06100, Italy
6
Section of Radiotherapy Department of Surgical and Biomedical Sciences, University of Perugia, Perugia 06100, Italy
*
Author to whom correspondence should be addressed.
Int. J. Mol. Sci. 2014, 15(6), 9878-9893; https://doi.org/10.3390/ijms15069878
Received: 30 March 2014 / Revised: 13 May 2014 / Accepted: 14 May 2014 / Published: 3 June 2014
(This article belongs to the Special Issue Brain Metastasis 2014)
Nuclear medicine techniques (single photon emission computerized tomography, SPECT, and positron emission tomography, PET) represent molecular imaging tools, able to provide in vivo biomarkers of different diseases. To investigate brain tumours and metastases many different radiopharmaceuticals imaged by SPECT and PET can be used. In this review the main and most promising radiopharmaceuticals available to detect brain metastases are reported. Furthermore the diagnostic contribution of the combination of SPECT and PET data with radiological findings (magnetic resonance imaging, MRI) is discussed. View Full-Text
Keywords: brain metastases; molecular imaging; PET; SPECT; MRI; fusion imaging brain metastases; molecular imaging; PET; SPECT; MRI; fusion imaging
Show Figures

Figure 1

MDPI and ACS Style

Palumbo, B.; Buresta, T.; Nuvoli, S.; Spanu, A.; Schillaci, O.; Fravolini, M.L.; Palumbo, I. SPECT and PET Serve as Molecular Imaging Techniques and in Vivo Biomarkers for Brain Metastases. Int. J. Mol. Sci. 2014, 15, 9878-9893.

Show more citation formats Show less citations formats

Article Access Map by Country/Region

1
Only visits after 24 November 2015 are recorded.
Back to TopTop