Next Article in Journal
Effects of Acrylamide on the Activity and Structure of Human Brain Creatine Kinase
Next Article in Special Issue
Release of Bacteriocins from Nanofibers Prepared with Combinations of Poly(D,L-lactide) (PDLLA) and Poly(Ethylene Oxide) (PEO)
Previous Article in Journal
Functional Analysis of Familial Asp67Glu and Thr1051Ser BRCA1 Mutations in Breast/Ovarian Carcinogenesis
Previous Article in Special Issue
Microscopic Investigation of Reversible Nanoscale Surface Size Dependent Protein Conjugation
Article Menu

Export Article

Open AccessReview
Int. J. Mol. Sci. 2009, 10(10), 4198-4209;

Regulation of Enzyme Activity through Interactions with Nanoparticles

School of Pharmaceutical Sciences, Shandong University, Jinan 250012, China
School of Chemistry and Chemical Engineering, Shandong University, Jinan 250100, China
St. Jude Children’s Research Hospital, Memphis, TN 38105, USA
Author to whom correspondence should be addressed.
Received: 18 August 2009 / Revised: 15 September 2009 / Accepted: 21 September 2009 / Published: 28 September 2009
(This article belongs to the Special Issue Bioactive Nanoparticles (special issue))
Full-Text   |   PDF [278 KB, uploaded 19 June 2014]


The structure and function of an enzyme can be altered by nanoparticles (NPs). The interaction between enzyme and NPs is governed by the key properties of NPs, such as structure, size, surface chemistry, charge and surface shape. Recent representative studies on the NP-enzyme interactions and the regulation of enzyme activity by NPs with different size, composition and surface modification are reviewed. View Full-Text
Keywords: enzyme activity; regulation; nanoparticle enzyme activity; regulation; nanoparticle
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Share & Cite This Article

MDPI and ACS Style

Wu, Z.; Zhang, B.; Yan, B. Regulation of Enzyme Activity through Interactions with Nanoparticles. Int. J. Mol. Sci. 2009, 10, 4198-4209.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics



[Return to top]
Int. J. Mol. Sci. EISSN 1422-0067 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top