Next Article in Journal
Design and Development of D‒α‒Tocopheryl Polyethylene Glycol Succinate‒block‒Poly(ε-Caprolactone) (TPGS−b−PCL) Nanocarriers for Solubilization and Controlled Release of Paclitaxel
Previous Article in Journal
New Estrone Oxime Derivatives: Synthesis, Cytotoxic Evaluation and Docking Studies
Open AccessArticle

Robust Hydrogel Adhesive with Dual Hydrogen Bond Networks

School of Materials Science and Chemical Engineering, Ningbo University of Technology, 201 Fenghua Road, Jiangbei, Ningbo 315211, China
*
Authors to whom correspondence should be addressed.
Academic Editor: Bruce P. Lee
Molecules 2021, 26(9), 2688; https://doi.org/10.3390/molecules26092688
Received: 30 March 2021 / Revised: 29 April 2021 / Accepted: 29 April 2021 / Published: 4 May 2021
Hydrogel adhesives are attractive for applications in intelligent soft materials and tissue engineering, but conventional hydrogels usually have poor adhesion. In this study, we designed a strategy to synthesize a novel adhesive with a thin hydrogel adhesive layer integrated on a tough substrate hydrogel. The adhesive layer with positive charges of ammonium groups on the polymer backbones strongly bonds to a wide range of nonporous materials’ surfaces. The substrate layer with a dual hydrogen bond system consists of (i) weak hydrogen bonds between N,N-dimethyl acrylamide (DMAA) and acrylic acid (AAc) units and (ii) strong multiple hydrogen bonds between 2-ureido-4[1H]-pyrimidinone (UPy) units. The dual hydrogen-bond network endowed the hydrogel adhesives with unique mechanical properties, e.g., toughness, highly stretchability, and insensitivity to notches. The hydrogel adhesion to four types of materials like glass, 316L stainless steel, aluminum, Al2O3 ceramic, and two biological tissues including pig skin and pig kidney was investigated. The hydrogel bonds strongly to dry solid surfaces and wet tissue, which is promising for biomedical applications. View Full-Text
Keywords: hydrogels; tissue adhesive; hydrogen bonds; stretchable; notch-insensitive hydrogels; tissue adhesive; hydrogen bonds; stretchable; notch-insensitive
Show Figures

Figure 1

MDPI and ACS Style

Jiang, Z.; Li, Y.; Shen, Y.; Yang, J.; Zhang, Z.; You, Y.; Lv, Z.; Yao, L. Robust Hydrogel Adhesive with Dual Hydrogen Bond Networks. Molecules 2021, 26, 2688. https://doi.org/10.3390/molecules26092688

AMA Style

Jiang Z, Li Y, Shen Y, Yang J, Zhang Z, You Y, Lv Z, Yao L. Robust Hydrogel Adhesive with Dual Hydrogen Bond Networks. Molecules. 2021; 26(9):2688. https://doi.org/10.3390/molecules26092688

Chicago/Turabian Style

Jiang, Zhiqiang; Li, Ya; Shen, Yirui; Yang, Jian; Zhang, Zongyong; You, Yujing; Lv, Zhongda; Yao, Lihui. 2021. "Robust Hydrogel Adhesive with Dual Hydrogen Bond Networks" Molecules 26, no. 9: 2688. https://doi.org/10.3390/molecules26092688

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Search more from Scilit
 
Search
Back to TopTop