The Role of Resveratrol in Human Male Fertility
Department of Clinical and Experimental Medicine, University of Catania, Via S. Sofia 78, 95123 Catania, Italy
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Academic Editors: Thomas Netticadan, Jeffrey Wigle and Pema Raj
Molecules 2021, 26(9), 2495; https://doi.org/10.3390/molecules26092495
Received: 30 March 2021
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Revised: 22 April 2021
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Accepted: 23 April 2021
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Published: 24 April 2021
(This article belongs to the Special Issue Resveratrol 2021: Recent Advances in the Application of Resveratrol to Improve Health)
Resveratrol (RSV) (3,4′,5 trihydroxystilbene) is a natural non-flavonoid polyphenol widely present in the Mediterranean diet. In particular, RSV is found in grapes, peanuts, berries, and red wine. Many beneficial effects of this molecule on human health have been reported. In fact, it improves some clinical aspects of various diseases, such as obesity, tumors, hypertension, Alzheimer’s disease, stroke, cardiovascular diseases, and diabetes mellitus. However, little is known about the relationship between this compound and male fertility and the few available results are often controversial. Therefore, this review evaluated the effects of RSV on human male fertility and the mechanisms through which this polyphenol could act on human spermatozoa.
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Keywords:
resveratrol; human male fertility; sperm parameters; cryopreservation
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
MDPI and ACS Style
Mongioì, L.M.; Perelli, S.; Condorelli, R.A.; Barbagallo, F.; Crafa, A.; Cannarella, R.; La Vignera, S.; Calogero, A.E. The Role of Resveratrol in Human Male Fertility. Molecules 2021, 26, 2495. https://doi.org/10.3390/molecules26092495
AMA Style
Mongioì LM, Perelli S, Condorelli RA, Barbagallo F, Crafa A, Cannarella R, La Vignera S, Calogero AE. The Role of Resveratrol in Human Male Fertility. Molecules. 2021; 26(9):2495. https://doi.org/10.3390/molecules26092495
Chicago/Turabian StyleMongioì, Laura M., Sarah Perelli, Rosita A. Condorelli, Federica Barbagallo, Andrea Crafa, Rossella Cannarella, Sandro La Vignera, and Aldo E. Calogero. 2021. "The Role of Resveratrol in Human Male Fertility" Molecules 26, no. 9: 2495. https://doi.org/10.3390/molecules26092495
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