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Article

Acylated Flavone O-Glucuronides from the Aerial Parts of Nepeta curviflora

1
Department of Chemistry, Birzeit University, Birzeit 627, Palestine
2
Department of Chemistry and Centre for Pharmacy, University of Bergen, Allégt. 41, N-5007 Bergen, Norway
*
Author to whom correspondence should be addressed.
Academic Editor: Natalizia Miceli
Molecules 2020, 25(17), 3782; https://doi.org/10.3390/molecules25173782
Received: 3 July 2020 / Revised: 3 August 2020 / Accepted: 11 August 2020 / Published: 20 August 2020
Nepeta curviflora Boiss. (Syrian catnip) is native to the Middle East. This medicinal plant is commonly used against nervous disorders, rheumatic pains, and high blood pressure. Herbal infusions prepared from various Nepeta spp. are extensively consumed as functional food. However, limited information has been known about the phenolic constituents of Syrian catnip. In this study, two acylated flavone 7-O-glucuronides, apigenin 7-O-(2″-O-(2‴-(E-caffeoyl)-β-glucuronopyranosyl)-β-glucuronopyranoside) (1) and luteolin 7-O-(2″-O-(2‴-(E-caffeoyl)-β-glucuronopyranosyl)-β-glucuronopyranoside) (2), along with the known phenolic compounds rosmarinic acid, caffeic acid, apigenin, and apigenin 7-O-β-glucopyranoside were isolated from the aerial parts of N. curviflora. The characterizations of these compounds were based on high-resolution mass spectrometry, UV, and extensive use of multidimensional NMR spectroscopy. The new compounds (1 and 2) were identified in the unmodified state and as dimethylesters. View Full-Text
Keywords: syrian catnip; Nepeta curviflora; lamiaceae; acylated flavone 7-O-glucuronosides syrian catnip; Nepeta curviflora; lamiaceae; acylated flavone 7-O-glucuronosides
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MDPI and ACS Style

Rabee, M.; Andersen, Ø.M.; Fossen, T.; Enerstvedt, K.H.; Abu Ali, H.; Rayyan, S. Acylated Flavone O-Glucuronides from the Aerial Parts of Nepeta curviflora. Molecules 2020, 25, 3782. https://doi.org/10.3390/molecules25173782

AMA Style

Rabee M, Andersen ØM, Fossen T, Enerstvedt KH, Abu Ali H, Rayyan S. Acylated Flavone O-Glucuronides from the Aerial Parts of Nepeta curviflora. Molecules. 2020; 25(17):3782. https://doi.org/10.3390/molecules25173782

Chicago/Turabian Style

Rabee, Maysaa, Øyvind M. Andersen, Torgils Fossen, Kjersti H. Enerstvedt, Hijazi Abu Ali, and Saleh Rayyan. 2020. "Acylated Flavone O-Glucuronides from the Aerial Parts of Nepeta curviflora" Molecules 25, no. 17: 3782. https://doi.org/10.3390/molecules25173782

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