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Open AccessReview

Hydrolyzed Collagen—Sources and Applications

Instituto de Ciencias Agropecuarias, Universidad Autónoma del Estado de Hidalgo, Av. Universidad km 1. Ex Hacienda de Aquetzalpa. Tulancingo, Hidalgo 43600, Mexico
Universidad Autónoma del Estado de Hidalgo, Escuela Superior de Apan, Carretera Apan-Calpulalpan s/n, Colonia, Chimalpa Tlalayote, Apan, Hidalgo 43920 Mexico
Regenerative, Modular & Developmental Engineering Laboratory (REMODEL), National University of Ireland Galway (NUI Galway), H91 TK33 Galway, Ireland
Science Foundation Ireland (SFI) Centre for Research in Medical Devices (CÚRAM) National University of Ireland Galway (NUI Galway), H91 TK33 Galway, Ireland
Author to whom correspondence should be addressed.
Academic Editors: Manuela Pintado, Ezequiel Coscueta and María Emilia Brassesco
Molecules 2019, 24(22), 4031;
Received: 7 October 2019 / Revised: 2 November 2019 / Accepted: 5 November 2019 / Published: 7 November 2019
(This article belongs to the Special Issue Bioproducts for Health)
Hydrolyzed collagen (HC) is a group of peptides with low molecular weight (3–6 KDa) that can be obtained by enzymatic action in acid or alkaline media at a specific incubation temperature. HC can be extracted from different sources such as bovine or porcine. These sources have presented health limitations in the last years. Recently research has shown good properties of the HC found in skin, scale, and bones from marine sources. Type and source of extraction are the main factors that affect HC properties, such as molecular weight of the peptide chain, solubility, and functional activity. HC is widely used in several industries including food, pharmaceutical, cosmetic, biomedical, and leather industries. The present review presents the different types of HC, sources of extraction, and their applications as a biomaterial. View Full-Text
Keywords: hydrolyzed collagen; peptide; antioxidant activity; denaturation; hydrolysates hydrolyzed collagen; peptide; antioxidant activity; denaturation; hydrolysates
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MDPI and ACS Style

León-López, A.; Morales-Peñaloza, A.; Martínez-Juárez, V.M.; Vargas-Torres, A.; Zeugolis, D.I.; Aguirre-Álvarez, G. Hydrolyzed Collagen—Sources and Applications. Molecules 2019, 24, 4031.

AMA Style

León-López A, Morales-Peñaloza A, Martínez-Juárez VM, Vargas-Torres A, Zeugolis DI, Aguirre-Álvarez G. Hydrolyzed Collagen—Sources and Applications. Molecules. 2019; 24(22):4031.

Chicago/Turabian Style

León-López, Arely; Morales-Peñaloza, Alejandro; Martínez-Juárez, Víctor M.; Vargas-Torres, Apolonio; Zeugolis, Dimitrios I.; Aguirre-Álvarez, Gabriel. 2019. "Hydrolyzed Collagen—Sources and Applications" Molecules 24, no. 22: 4031.

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