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The Polyphenols as Potential Agents in Prevention and Therapy of Prostate Diseases

Clinic of Urology, Clinical Centre of Serbia, 11060 Belgrade, Serbia
Faculty of Medicine, University of Belgrade; Bulevar Despota Stefana 142, 11060 Belgrade, Serbia
Faculty of Chemistry, University of Belgrade, Studentski trg 12-16, P.O. Box 51, 11158 Belgrade, Serbia
Institute for Biological Research “Siniša Stanković”, University of Belgrade, Bulevar despota Stefana 142, 11060 Belgrade, Serbia
Department for Biomedical Sciences, State University at Novi Pazar, 36300 Novi Pazar, Serbia
Author to whom correspondence should be addressed.
Molecules 2019, 24(21), 3982;
Received: 27 September 2019 / Revised: 25 October 2019 / Accepted: 28 October 2019 / Published: 4 November 2019
(This article belongs to the Special Issue Phytochemicals in Medicine and Food)
In recent years, the progress of science and medicine greatly has influenced human life span and health. However, lifestyle habits, like physical activity, smoking cessation, moderate alcohol consumption, diet, and maintaining a normal body weight represent measures that greatly reduce the risk of various diseases. The type of diet is very important for disease development. Numerous epidemiological clinical data confirm that longevity is linked to predominantly plant-based diets and it is related to a long life; whereas the western diet, rich in red meat and fats, increases the risk of oxidative stress and thus the risk of developing various diseases and pre-aging. This review is focused on the bioavailability of polyphenols and the use of polyphenols for the prevention of prostate diseases. Special focus in this paper is placed on the isoflavonoids and flavan-3-ols, subgroups of polyphenols, and their protective effects against the development of prostate diseases. View Full-Text
Keywords: polyphenols; prostate; cancer; isoflavones; flavan-3-ols polyphenols; prostate; cancer; isoflavones; flavan-3-ols
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Pejčić, T.; Tosti, T.; Džamić, Z.; Gašić, U.; Vuksanović, A.; Dolićanin, Z.; Tešić, Ž. The Polyphenols as Potential Agents in Prevention and Therapy of Prostate Diseases. Molecules 2019, 24, 3982.

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