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Sesquiterpenoids from Artemisia vestita and Their Antifeedant and Antifungal Activities

by Ying-Hui Ding 1,†, Hui-Ting Wang 1,†, Sha Shi 1,2,*, Yao Meng 1, Jin-Chao Feng 1 and Hai-Bo Wu 1
1
College of Life and Environmental Sciences, Minzu University of China, Beijing 100081, China
2
Center on Translational Neuroscience, Minzu University of China, Beijing 100081, China
*
Author to whom correspondence should be addressed.
These authors contributed equally to this work.
Molecules 2019, 24(20), 3671; https://doi.org/10.3390/molecules24203671
Received: 27 September 2019 / Revised: 7 October 2019 / Accepted: 11 October 2019 / Published: 11 October 2019
(This article belongs to the Section Natural Products Chemistry)
Four new sesquiterpenoids, named artemivestinolide D–G (14) and three known sesquiterpenoids (57), were isolated from Artemisia vestita. The structures of these new compounds were determined based on extensive spectroscopic data analyses. Furthermore, the electronic circular dichroism data determined the absolute configurations of the new compounds. The antifeedant and antifungal activities of the isolates were evaluated against third-instar larvae of Plutella xylostella and three plant pathogenic fungi. Compounds 17 showed moderate antifeedant activities and compounds 14 and 67 exhibited antifungal activities. View Full-Text
Keywords: Artemisia vestita; sesquiterpenoids; absolute configuration; antifeedant; antifungal Artemisia vestita; sesquiterpenoids; absolute configuration; antifeedant; antifungal
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Ding, Y.-H.; Wang, H.-T.; Shi, S.; Meng, Y.; Feng, J.-C.; Wu, H.-B. Sesquiterpenoids from Artemisia vestita and Their Antifeedant and Antifungal Activities. Molecules 2019, 24, 3671.

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