Next Article in Journal
Analysis of Flavonoid Metabolites in Citrus Peels (Citrus reticulata “Dahongpao”) Using UPLC-ESI-MS/MS
Next Article in Special Issue
Marine Collagen Peptides Promote Cell Proliferation of NIH-3T3 Fibroblasts via NF-κB Signaling Pathway
Previous Article in Journal
The Flow Dependent Adhesion of von Willebrand Factor (VWF)-A1 Functionalized Nanoparticles in an in Vitro Coronary Stenosis Model
Open AccessReview

An Updated Review on Pharmaceutical Properties of Gamma-Aminobutyric Acid

Faculty of Natural Sciences, Thu Dau Mot University, Thu Dau Mot City 820000, Vietnam
NTT Hi-Tech Institute, Nguyen Tat Thanh University, Ho Chi Minh City 700000, Vietnam
Author to whom correspondence should be addressed.
Academic Editors: María Dolores Torres and Elena Falqué López
Molecules 2019, 24(15), 2678;
Received: 27 May 2019 / Revised: 8 July 2019 / Accepted: 19 July 2019 / Published: 24 July 2019
Gamma-aminobutyric acid (Gaba) is a non-proteinogenic amino acid that is widely present in microorganisms, plants, and vertebrates. So far, Gaba is well known as a main inhibitory neurotransmitter in the central nervous system. Its physiological roles are related to the modulation of synaptic transmission, the promotion of neuronal development and relaxation, and the prevention of sleeplessness and depression. Besides, various pharmaceutical properties of Gaba on non-neuronal peripheral tissues and organs were also reported due to anti-hypertension, anti-diabetes, anti-cancer, antioxidant, anti-inflammation, anti-microbial, anti-allergy, hepato-protection, reno-protection, and intestinal protection. Therefore, Gaba may be considered as potential alternative therapeutics for prevention and treatment of various diseases. Accordingly, this updated review was mainly focused to describe the pharmaceutical properties of Gaba as well as emphasize its important role regarding human health. View Full-Text
Keywords: anti-hypertension; bioactivity; Gaba; Gaba-rich product; health benefit anti-hypertension; bioactivity; Gaba; Gaba-rich product; health benefit
Show Figures

Figure 1

MDPI and ACS Style

Ngo, D.-H.; Vo, T.S. An Updated Review on Pharmaceutical Properties of Gamma-Aminobutyric Acid. Molecules 2019, 24, 2678.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

Search more from Scilit
Back to TopTop