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Open AccessReview

An Updated Review on Pharmaceutical Properties of Gamma-Aminobutyric Acid

1
Faculty of Natural Sciences, Thu Dau Mot University, Thu Dau Mot City 820000, Vietnam
2
NTT Hi-Tech Institute, Nguyen Tat Thanh University, Ho Chi Minh City 700000, Vietnam
*
Author to whom correspondence should be addressed.
Academic Editors: María Dolores Torres and Elena Falqué López
Molecules 2019, 24(15), 2678; https://doi.org/10.3390/molecules24152678
Received: 27 May 2019 / Revised: 8 July 2019 / Accepted: 19 July 2019 / Published: 24 July 2019
Gamma-aminobutyric acid (Gaba) is a non-proteinogenic amino acid that is widely present in microorganisms, plants, and vertebrates. So far, Gaba is well known as a main inhibitory neurotransmitter in the central nervous system. Its physiological roles are related to the modulation of synaptic transmission, the promotion of neuronal development and relaxation, and the prevention of sleeplessness and depression. Besides, various pharmaceutical properties of Gaba on non-neuronal peripheral tissues and organs were also reported due to anti-hypertension, anti-diabetes, anti-cancer, antioxidant, anti-inflammation, anti-microbial, anti-allergy, hepato-protection, reno-protection, and intestinal protection. Therefore, Gaba may be considered as potential alternative therapeutics for prevention and treatment of various diseases. Accordingly, this updated review was mainly focused to describe the pharmaceutical properties of Gaba as well as emphasize its important role regarding human health. View Full-Text
Keywords: anti-hypertension; bioactivity; Gaba; Gaba-rich product; health benefit anti-hypertension; bioactivity; Gaba; Gaba-rich product; health benefit
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Ngo, D.-H.; Vo, T.S. An Updated Review on Pharmaceutical Properties of Gamma-Aminobutyric Acid. Molecules 2019, 24, 2678.

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