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Review

Biological Properties and Bioactive Components of Allium cepa L.: Focus on Potential Benefits in the Treatment of Obesity and Related Comorbidities

by
Mariangela Marrelli
*,
Valentina Amodeo
,
Giancarlo Statti
and
Filomena Conforti
Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, I-87036 Rende (CS), Italy
*
Author to whom correspondence should be addressed.
Molecules 2019, 24(1), 119; https://doi.org/10.3390/molecules24010119
Submission received: 28 November 2018 / Revised: 20 December 2018 / Accepted: 24 December 2018 / Published: 30 December 2018
(This article belongs to the Special Issue Natural Bioactives in Anti-Obesity Therapy)
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Abstract

Common onion (Allium cepa L.) is one of the oldest cultivated plants, utilized worldwide as both vegetable and flavouring. This species is known to contain sulphur amino acids together with many vitamins and minerals. A variety of secondary metabolites, including flavonoids, phytosterols and saponins, have also been identified. Despite the predominant use of this plant as food, a wide range of beneficial effects have also been proved. Different biological properties, such as antioxidant, antimicrobial and antidiabetic, have been reported. The aim of this review is to provide an overview of the studies concerning the beneficial effects of this species against obesity and its related comorbidities, such as hyperlipidaemia, hypertension and diabetes. Both in vitro and in vivo results about onion dietary supplementation have been taken into account. Furthermore, this review examines the possible role of onion bioactive components in modulating or preventing weight-gain or related diseases, as well as the possible mechanisms behind their activity.
Keywords: Allium; bioactive compounds; diabetes; hyperlipidaemia; obesity; onion; organosulfur compounds; quercetin Allium; bioactive compounds; diabetes; hyperlipidaemia; obesity; onion; organosulfur compounds; quercetin

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MDPI and ACS Style

Marrelli, M.; Amodeo, V.; Statti, G.; Conforti, F. Biological Properties and Bioactive Components of Allium cepa L.: Focus on Potential Benefits in the Treatment of Obesity and Related Comorbidities. Molecules 2019, 24, 119. https://doi.org/10.3390/molecules24010119

AMA Style

Marrelli M, Amodeo V, Statti G, Conforti F. Biological Properties and Bioactive Components of Allium cepa L.: Focus on Potential Benefits in the Treatment of Obesity and Related Comorbidities. Molecules. 2019; 24(1):119. https://doi.org/10.3390/molecules24010119

Chicago/Turabian Style

Marrelli, Mariangela, Valentina Amodeo, Giancarlo Statti, and Filomena Conforti. 2019. "Biological Properties and Bioactive Components of Allium cepa L.: Focus on Potential Benefits in the Treatment of Obesity and Related Comorbidities" Molecules 24, no. 1: 119. https://doi.org/10.3390/molecules24010119

APA Style

Marrelli, M., Amodeo, V., Statti, G., & Conforti, F. (2019). Biological Properties and Bioactive Components of Allium cepa L.: Focus on Potential Benefits in the Treatment of Obesity and Related Comorbidities. Molecules, 24(1), 119. https://doi.org/10.3390/molecules24010119

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