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Open AccessFeature PaperCommunication
Molecules 2018, 23(4), 914;

One-Pot, Highly Stereoselective Synthesis of Dithioacetal-α,α-Diglycosides

Laboratoire d’Innovation Moléculaire et Application (LIMA), Université de Strasbourg, Université de Haute-Alsace, CNRS (UMR 7042), Equipe Synthèse Organique et Molécules Bioactives (SYBIO), Ecole Européenne de Chimie, Polymères et Matériaux, 25 rue Becquerel, 67000 Strasbourg, France
These authors contributed equally to the work.
Author to whom correspondence should be addressed.
Received: 28 March 2018 / Revised: 12 April 2018 / Accepted: 13 April 2018 / Published: 15 April 2018
(This article belongs to the Special Issue Glycomimetics: Design, Synthesis and Therapeutic Applications)
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A one-step access to dithioacetal-α,α-diglycosides is reported. The synthetic strategy is based on the thioacetalization of aldehydes or ketones via highly stereoselective ring-opening of 1,6 anhydrosugars with bis(trimethylsilyl)sulfide. View Full-Text
Keywords: glycomimetics; thioglycosides; dithioacetals; 1,6-anhydrosugars; ring-opening glycomimetics; thioglycosides; dithioacetals; 1,6-anhydrosugars; ring-opening

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Céspedes Dávila, M.F.; Schneider, J.P.; Godard, A.; Hazelard, D.; Compain, P. One-Pot, Highly Stereoselective Synthesis of Dithioacetal-α,α-Diglycosides. Molecules 2018, 23, 914.

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