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Molecules 2018, 23(2), 480; https://doi.org/10.3390/molecules23020480

Sulphated Flavonoids: Biosynthesis, Structures, and Biological Activities

1
Department of Chemistry and Physics, Agrarian Sciences Center, Universidade Federal da Paraíba, Areia 58397-000, PB, Brazil
2
Post graduation Program in Bioactive Natural and Synthetic Products, Health Sciences Center, Universidade Federal da Paraíba, João Pessoa 58051-900, PB, Brazil
3
Post graduation in Development and Technological Innovation in Medicines, Health Sciences Center, Universidade Federal da Paraíba, João Pessoa 58051-900, PB, Brazil
*
Author to whom correspondence should be addressed.
Received: 13 January 2018 / Revised: 7 February 2018 / Accepted: 12 February 2018 / Published: 23 February 2018
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Abstract

The great diversity of enzymatic reactions in plant secondary metabolism allows the continuous discovery of new natural compounds and derivatives. Flavonoids, for example, can be found as aglycone or as several sorts of glycosylated, acetylated, methylated, and sulphated derivatives. This review focuses on sulphated flavonoids, an uncommon group of flavonoid derivatives found in some plant families. This work presents a compilation of sulphated flavonoids and their natural sources reported in the literature. Biosynthetic aspects and biological activities have also been reviewed, showing that these particular kinds of natural compounds play an interesting role in plant metabolism, as well as being potential candidates for the development of new drugs. View Full-Text
Keywords: sulphated flavonoids; sulphation; secondary metabolism; sulphotransferases sulphated flavonoids; sulphation; secondary metabolism; sulphotransferases
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Teles, Y.C.F.; Souza, M.S.R.; Souza, M.F.V. Sulphated Flavonoids: Biosynthesis, Structures, and Biological Activities. Molecules 2018, 23, 480.

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