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Open AccessFeature PaperReview

Liquid Chromatographic Strategies for Separation of Bioactive Compounds in Food Matrices

Department of Chemistry, Sapienza University of Rome, Piazzale Aldo Moro, 00185 Roma, Italy
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Molecules 2018, 23(12), 3091; https://doi.org/10.3390/molecules23123091
Received: 23 September 2018 / Revised: 31 October 2018 / Accepted: 21 November 2018 / Published: 27 November 2018
Nowadays, there is an increasing attention for nutraceuticals and, in general, bioactive compounds naturally present in food. Indeed, the possibility of preserving human health and preventing disease (e.g., cardiovascular diseases, cancer etc.) by the intake of healthy food is attractive for both consumers and food industries. In turn, research in this field was also prompted significantly, with the aim of characterizing these bioactive compounds and ascribe to them a specific activity. The bioactive compounds can belong to several chemical classes. However, their chemical diversity and presence in complex matrices, such as food, make it challenging both their isolation and characterization. To tackle this issue, efficient separation systems are needed, which are mainly based on chromatography. In this context, this mini-review aims to provide the reader with an overview of the most relevant and recent approaches for the separation of the most common bioactive compounds in food, in particular polyphenols, phenols, carotenoids, and peptides, by liquid chromatography approaches. View Full-Text
Keywords: bioactive compounds; carotenoids; liquid chromatography; peptides; polyphenols bioactive compounds; carotenoids; liquid chromatography; peptides; polyphenols
MDPI and ACS Style

Cavaliere, C.; Capriotti, A.L.; La Barbera, G.; Montone, C.M.; Piovesana, S.; Laganà, A. Liquid Chromatographic Strategies for Separation of Bioactive Compounds in Food Matrices. Molecules 2018, 23, 3091.

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