A New N-methoxypyridone from the Co-Cultivation of Hawaiian Endophytic Fungi Camporesia sambuci FT1061 and Epicoccum sorghinum FT1062
Abstract
:1. Introduction
2. Results and Discussion
3. Materials and Methods
3.1. General Experimental Procedures
3.2. Isolation and Identification of Fungal Strain
3.3. Cultivation
3.4. Isolation of Compounds 1–5
3.5. Charaterization of Compound 1
3.6. Anti-Microbial Activity
3.7. Anti-Proliferative Activity
3.8. ECD Calculations
4. Conclusions
Supplementary Materials
Acknowledgments
Author Contributions
Conflicts of Interest
References
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Sample Availability: Samples of the compounds 1–5 are available from the authors. |
No. | 1 in Methanol-d4 | 1 in CDCl3 | ||
---|---|---|---|---|
δH, J (Hz) | δC a | HMBC Correlation | δH, J (Hz) | |
2 | 159.4 | |||
3 | 114.6 | |||
4 | 165.8 | |||
5 | 6.03, d, 7.6 | 101.5 | C-3, C-4 | 5.84, d, 7.6 |
6 | 7.73, dd, 7.6, 0.8 | 136.6 | C-2, C-4 | 7.37, dd, 7.6, 0.8 |
7 | 2.07, d, 11.6 | 50.3 | C-2, C-3, C-4, C-12, | 2.04, d, 11.6 |
C-8, C-9, C-13, C-16 | ||||
8 | 2.69, m | 27.3 | 2.75, m | |
9a | 1.84, dt, 13.5, 4.0 | 44.2 | C-7, C-11, C-8, C-10, C-17 | 1.82, dt, 13.5, 4.0 |
9b | 0.85, br.d, 13.5 | C-7, C-11, C-8, C-10, C-17, C-18 | 0.82, br.d, 13.5 | |
10 | 1.69, m | 33.7 | 1.66, m | |
11 | 3.03, d, 10.4 | 84.7 | C-9, C-10, C-12, C-13, C-16, C-17 | 3.08, d, 10.3 |
12 | 45.8 | |||
13 | 4.10, dd, 10.8, 1.6 | 94.9 | C-4, C-11, C-12, C-14, C-15, C-16 | 4.06, dd, 10.9, 1.7 |
14a | 2.05, m | 27.4 | C-12, C-13, C-15 | 2.00, m |
14b | 1.27, m | C-13, C-15 | 1.25, m | |
15 | 1.12, t, 7.4 | 11.5 | C-13, C-14 | 1.08, t, 7.3 |
16 | 0.71, s | 9.8 | C-7, C-11, C-12, C-13 | 0.73, s |
17 | 0.99, d, 6.3 | 18.7 | C-9, C-10, C-11 | 0.97, d, 6.4 |
18 | 1.07, d, 6.0 | 23.7 | C-7, C-8, C-9 | 1.08, d, 5.9 |
19 | 3.98, s | 65.0 | 4.01, s |
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Li, C.; Sarotti, A.M.; Yang, B.; Turkson, J.; Cao, S. A New N-methoxypyridone from the Co-Cultivation of Hawaiian Endophytic Fungi Camporesia sambuci FT1061 and Epicoccum sorghinum FT1062. Molecules 2017, 22, 1166. https://doi.org/10.3390/molecules22071166
Li C, Sarotti AM, Yang B, Turkson J, Cao S. A New N-methoxypyridone from the Co-Cultivation of Hawaiian Endophytic Fungi Camporesia sambuci FT1061 and Epicoccum sorghinum FT1062. Molecules. 2017; 22(7):1166. https://doi.org/10.3390/molecules22071166
Chicago/Turabian StyleLi, Chunshun, Ariel M. Sarotti, Baojun Yang, James Turkson, and Shugeng Cao. 2017. "A New N-methoxypyridone from the Co-Cultivation of Hawaiian Endophytic Fungi Camporesia sambuci FT1061 and Epicoccum sorghinum FT1062" Molecules 22, no. 7: 1166. https://doi.org/10.3390/molecules22071166