Next Article in Journal
Synthesis of Hydroxymethylenebisphosphonic Acid Derivatives in Different Solvents
Previous Article in Journal
Anti-Inflammatory Effects of 6,8-Diprenyl-7,4′-dihydroxyflavanone from Sophora tonkinensis on Lipopolysaccharide-Stimulated RAW 264.7 Cells
Open AccessArticle

Insecticidal Properties of a Highly Potent Wax Isolated from Dolichandra cynanchoides Cham

Unidad Asociada Area Cs. Agr. Ing. Bio. y S.-CONICET-Universidad Católica de Córdoba, Armada Argentina 3555, 5016 Córdoba, Argentina
*
Author to whom correspondence should be addressed.
Academic Editor: Derek J. McPhee
Molecules 2016, 21(8), 1039; https://doi.org/10.3390/molecules21081039
Received: 7 July 2016 / Revised: 1 August 2016 / Accepted: 4 August 2016 / Published: 11 August 2016
(This article belongs to the Section Natural Products Chemistry)
Bioassay-guided fractionation of an ethanolic extract of the aerial parts of Dolichandra cynanchoides Cham. (Bignoniaceae) led to the isolation of a natural wax with anti-insect activity against Spodoptera frugiperda (Noctuidae) and Epilachna paenulata (Coleptera). The compound was identified spectroscopically as an ester of a C27 fatty acid and a C25 alcohol, pentacosyl heptacosanoate (1). The effective doses of 1 for 50% feeding inhibition (ED50) of S. frugiperda and E. paenulata were 0.82 and 8.53 µg/cm2, respectively, in a choice test, while azadirachtin showed ED50 of 0.10 and 0.59 µg/cm2, respectively. In a no-choice test, both insects refused to feed on leaves treated with 1 at doses of 0.1 µg/cm2 or greater inhibiting larval growth and dramatically reducing survival. The lethal doses 50 (LD50) of 1 were 0.39 and 0.68 µg/cm2 for S. frugiperda and E. paenulata, respectively. These results indicate that 1 has potential for development as botanical insecticides. Similar esters might be obtainable in large quantities as many edible crops produce wax esters that are discarded during food processing. Research on these materials could lead to the detection of similar waxes with insecticidal activity. View Full-Text
Keywords: Dolichandra cynanchoides; wax; Spodoptera frugiperda; Epilachna paenulata; antifeedant Dolichandra cynanchoides; wax; Spodoptera frugiperda; Epilachna paenulata; antifeedant
Show Figures

Graphical abstract

MDPI and ACS Style

Díaz Napal, G.; Carpinella, M.C.; Palacios, S.M. Insecticidal Properties of a Highly Potent Wax Isolated from Dolichandra cynanchoides Cham. Molecules 2016, 21, 1039.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop