Next Article in Journal
Aroylhydrazone Cu(II) Complexes in keto Form: Structural Characterization and Catalytic Activity towards Cyclohexane Oxidation
Next Article in Special Issue
Plectranthus amboinicus (Lour.) Spreng: Botanical, Phytochemical, Pharmacological and Nutritional Significance
Previous Article in Journal
Bryonolic Acid, a Triterpenoid, Protect Against N-methyl-d-Aspartate-Induced Neurotoxicity in PC12 Cells
Previous Article in Special Issue
Compound Library Screening Identified Cardiac Glycoside Digitoxin as an Effective Growth Inhibitor of Gefitinib-Resistant Non-Small Cell Lung Cancer via Downregulation of α-Tubulin and Inhibition of Microtubule Formation

Sinigrin and Its Therapeutic Benefits

Centre of Excellence for Pharmaceutical Sciences, North-West University, Private Bag X6001, Potchefstroom 2520, South Africa
Author to whom correspondence should be addressed.
Academic Editor: Christopher W. K. Lam
Molecules 2016, 21(4), 416;
Received: 30 January 2016 / Revised: 7 March 2016 / Accepted: 22 March 2016 / Published: 29 March 2016
(This article belongs to the Collection Herbal Medicine Research)
Sinigrin (allyl-glucosinolate or 2-propenyl-glucosinolate) is a natural aliphatic glucosinolate present in plants of the Brassicaceae family, such as broccoli and brussels sprouts, and the seeds of Brassica nigra (mustard seeds) which contain high amounts of sinigrin. Since ancient times, mustard has been used by mankind for its culinary, as well as medicinal, properties. It has been systematically described and evaluated in the classical Ayurvedic texts. Studies conducted on the pharmacological activities of sinigrin have revealed anti-cancer, antibacterial, antifungal, antioxidant, anti-inflammatory, wound healing properties and biofumigation. This current review will bring concise information about the known therapeutic activities of sinigrin. However, the information on known biological activities is very limited and, hence, further studies still need to be conducted and its molecular mechanisms also need to be explored. This review on the therapeutic benefits of sinigrin can summarize current knowledge about this unique phytocompounds. View Full-Text
Keywords: glucosinolates; sinigrin; anticancer; mustard; Brassicaceae family; myrosinase glucosinolates; sinigrin; anticancer; mustard; Brassicaceae family; myrosinase
Show Figures

Graphical abstract

MDPI and ACS Style

Mazumder, A.; Dwivedi, A.; Du Plessis, J. Sinigrin and Its Therapeutic Benefits. Molecules 2016, 21, 416.

AMA Style

Mazumder A, Dwivedi A, Du Plessis J. Sinigrin and Its Therapeutic Benefits. Molecules. 2016; 21(4):416.

Chicago/Turabian Style

Mazumder, Anisha, Anupma Dwivedi, and Jeanetta Du Plessis. 2016. "Sinigrin and Its Therapeutic Benefits" Molecules 21, no. 4: 416.

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

Back to TopTop