Next Article in Journal
Synergistic Effects of Nucleating Agents and Plasticizers on the Crystallization Behavior of Poly(lactic acid)
Next Article in Special Issue
Antimicrobial and Seasonal Evaluation of the Carvacrol-Chemotype Oil from Lippia origanoides Kunth.
Previous Article in Journal
Comparative Pharmacokinetics of Hypaconitine after Oral Administration of Pure Hypaconitine, Aconitum carmichaelii Extract and Sini Decoction to Rats
Previous Article in Special Issue
Halofuginone — The Multifaceted Molecule
Open AccessArticle

Cytotoxic Activity and Composition of Petroleum Ether Extract from Magydaris tomentosa (Desf.) W. D. J. Koch (Apiaceae)

1
Department of Pharmacy, University of Salerno, Via Giovanni Paolo II 132, Salerno 84084, Italy
2
Department of Pharmacy, University of Naples "Federico II", Via Domenico Montesano, Napoli 49 80131, Italy
3
Department STEBICEF, University of Palermo, Viale delle Scienze, Parco d'Orleans II, Palermo 90128, Italy
4
Laboratoire des Plantes Extremophiles—Biotechnologic Center Borj-CedriaTechnopark, B.P. 901, Hammam-Lif 2050, Tunisia
*
Author to whom correspondence should be addressed.
Academic Editor: Isabel C. F. R. Ferreira
Molecules 2015, 20(1), 1571-1578; https://doi.org/10.3390/molecules20011571
Received: 30 October 2014 / Accepted: 9 January 2015 / Published: 16 January 2015
(This article belongs to the Collection Bioactive Compounds)
The petroleum ether extract of Magydaris tomentosa flowers (Desf.) W. D. J. Koch has been analyzed by GC-MS. It is mainly constituted by furanocoumarins such as xanthotoxin, xanthotoxol, isopimpinellin, and bergaptene. Other coumarins such as 7-methoxy-8-(2-formyl-2-methylpropyl) coumarin and osthole also occurred. The antiproliferative activity of Magydaris tomentosa flower extract has been evaluated in vitro on murine monocye/macrophages (J774A.1), human melanoma (A375) and human breast cancer (MCF-7) tumor cell lines, showing a major activity against the latter. View Full-Text
Keywords: Magydaris tomentosa; coumarins; furanocoumarins; xanthotoxin; xanthotoxol; isopimpinellin; osthole; bergaptene; MCF-7 Magydaris tomentosa; coumarins; furanocoumarins; xanthotoxin; xanthotoxol; isopimpinellin; osthole; bergaptene; MCF-7
Show Figures

Figure 1

MDPI and ACS Style

Autore, G.; Marzocco, S.; Formisano, C.; Bruno, M.; Rosselli, S.; Jemia, M.B.; Senatore, F. Cytotoxic Activity and Composition of Petroleum Ether Extract from Magydaris tomentosa (Desf.) W. D. J. Koch (Apiaceae). Molecules 2015, 20, 1571-1578.

Show more citation formats Show less citations formats

Article Access Map by Country/Region

1
Only visits after 24 November 2015 are recorded.
Search more from Scilit
 
Search
Back to TopTop