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Phytochemical Analysis of Pfaffia glomerata Inflorescences by LC-ESI-MS/MS

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Pharmaceutical Sciences Postgraduate Program, Department of Pharmacy, State University of Maringá, Av. Colombo, 5790, Maringá, Paraná 87020-900, Brazil
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Department of Chemistry, State University of Maringá, Av. Colombo, 5790, Maringá, Paraná 87020-900, Brazil
*
Author to whom correspondence should be addressed.
Molecules 2014, 19(10), 15720-15734; https://doi.org/10.3390/molecules191015720
Received: 4 August 2014 / Revised: 15 September 2014 / Accepted: 22 September 2014 / Published: 29 September 2014
(This article belongs to the Section Natural Products Chemistry)
Pfaffia glomerata contains high levels of β-ecdysone, which has shown a range of beneficial pharmacological effects. The present study demonstrated that inflorescences of P. glomerata contain other important bioactive compounds in addition to β-ecdysone. The identification of compounds from inflorescences using liquid chromatography coupled with electrospray ionization tandem mass spectrometry (LC-ESI-MS/MS) was performed for the first time. The eight compounds identified were β-ecdysone, flavonoid glycosides such as quercetin-3-O-glucoside, kaempferol-3-O-glucoside and kaempferol-3-O-(6-p-coumaroyl)-glucoside, oleanane-type triterpenoid saponins such as ginsenoside Ro and chikusetsusaponin IV, in addition to oleanonic acid and gluconic acid. This study provided information on the phytochemicals contained in P. glomerata inflorescences revealing the potential application of this plant part as raw material for the phytotherapeutic and cosmetic industries. View Full-Text
Keywords: Pfaffia glomerata; inflorescences; LC-ESI-MS/MS; β-ecdysone; flavonoid glycosides; triterpenoid saponins Pfaffia glomerata; inflorescences; LC-ESI-MS/MS; β-ecdysone; flavonoid glycosides; triterpenoid saponins
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Felipe, D.F.; Brambilla, L.Z.S.; Porto, C.; Pilau, E.J.; Cortez, D.A.G. Phytochemical Analysis of Pfaffia glomerata Inflorescences by LC-ESI-MS/MS. Molecules 2014, 19, 15720-15734.

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