Next Article in Journal
Small Molecule Library Synthesis Using Segmented Flow
Next Article in Special Issue
Acetylcholinesterase-inhibiting Alkaloids from Zephyranthes concolor
Previous Article in Journal
Pyrazinecarboxamides as Potential Elicitors of Flavonolignan and Flavonoid Production in Silybum marianum and Ononis arvensis Cultures In Vitro
Previous Article in Special Issue
Anti-Inflammatory Activity of Alkaloids: An Update from 2000 to 2010
Article Menu

Export Article

Open AccessArticle

Polar Compounds Isolated from the Leaves of Albertisia delagoensis (Menispermaceae)

School of Biological and Chemical Sciences, Queen Mary University of London, Mile End Road, London E1 4NS, UK
Department of Botany, University of Zululand, P/Bag X1001, Kwa-Dlangezwa 3880, South Africa
Department of Surgery and Cancer, Imperial College London, South Kensington Campus, London SW7 2AZ, UK
Author to whom correspondence should be addressed.
Molecules 2011, 16(11), 9153-9160;
Received: 8 October 2011 / Revised: 21 October 2011 / Accepted: 27 October 2011 / Published: 2 November 2011
(This article belongs to the Special Issue Alkaloids: Novel Therapeutic Perspectives)
PDF [193 KB, uploaded 18 June 2014]


Aqueous infusions of the leaves of the shrub Albertisia delagoensis (Menispermaceae) are used in South Africa in traditional Zulu medicine to alleviate a variety of symptoms, including fever, and intestinal problems. We report the analysis of such an aqueous extract using the HPLC-NMR technique. A number of polar compounds were identified, including proto-quercitol, nicotinic acid, allantoic acid, 3,4-dihydroxy-benzoic acid, phthalic acid and the aporphine alkaloid derivative roemrefidine. Allantoic acid and roemrefidine have been fully characterised by 1H- and 13C-NMR and mass spectrometry. Earlier reports of antiplasmodial activity of roemrefidine and of A. delagoensis extracts are correlated with this study and with the antipyretic properties of neutral aqueous extracts. View Full-Text
Keywords: Albertisia delagoensis; traditional medicine; roemrefidine; allantoic acid; HPLC-NMR Albertisia delagoensis; traditional medicine; roemrefidine; allantoic acid; HPLC-NMR

Figure 1

This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Share & Cite This Article

MDPI and ACS Style

Hawkes, G.E.; Wet, H.; Li, J. Polar Compounds Isolated from the Leaves of Albertisia delagoensis (Menispermaceae). Molecules 2011, 16, 9153-9160.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics



[Return to top]
Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top