Topical Collection "Post-Transcriptional Gene Regulation by Ribonucleoprotein Complexes"

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A topical collection in International Journal of Molecular Sciences (ISSN 1422-0067). This collection belongs to the section "Biochemistry, Molecular Biology and Biophysics".

Editor

Collection Editor
Dr. Kotb Abdelmohsen
Laboratory of Molecular Biology and Immunology; National Institute on Aging-Intramural Research Program; National Institutes of Health; Baltimore, MD USA
E-Mail: abdelmohsenk@grc.nia.nih.gov
Interests: cancer; aging; post-transcriptional gene regulation; cell signaling; oxidative stress; RNA-binding proteins; mRNA stability; mRNA translation; long non-coding RNAs; micro-RNA (miRNA)

Topical Collection Information

Dear Colleagues,

Post-transcriptional gene regulation by Ribonucleoprotein complexes. Ribonucleoprotein complexes are widely present in eukaryotic cells representing protein interactions with coding and non-coding RNAs. In the last few years we observed a great advance in identifying the precise protein-bound RNA sequences through the technology of RNA sequencing. These interactions are major regulators of post-transcriptional gene expression.  They control RNA splicing, mRNA export, stability and translation. They regulate microRNA (miRNA) processing through binding to primary, precursor, and mature sequences. RNA-binding proteins also bind long non-coding RNAs (lncRNAs) to guide them through their interactions with mRNA to regulate mRNA stability or translation.

The goal of this collection is to introduce the recent advances in the area of post-transcriptional gene regulation through RNA-protein interactions. The issue will generally focus on RNA-binding proteins and their effects on mRNA stability, translation and subcellular localization. The mechanisms and biological consequences of assembly of ribonucleoprotein complexes in which non-coding RNAs (lncRNAs and miRNAs) are the binding partners will be also addressed in this issue. Authors are also encouraged to review the recent progress in large-scale experimental approaches such as deep sequencing of total RNA and PAR-CLIP (photoactivatable-ribonucleoside-enhanced crosslinking and immunoprecipitation) of protein-bound RNAs. It is also important to review the new developments and challenges in computational methods that identify and characterize protein-bound cis-regulatory RNA sequences.

Dr. Kotb Abdelmohsen
Collection Editor

Manuscript Submission Information

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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1600 CHF (Swiss Francs).

Keywords

  • post-transcriptional gene regulation
  • transcriptome
  • RNA-binding proteins
  • mRNA stability
  • mRNA translation
  • RNA metabolism
  • RNA export
  • long non-coding RNAs
  • Micro-RNA (miRNA)
  • PAR-CLIP
  • deep sequencing

Published Papers (15 papers)


2014  ( 1 paper )


2013  ( 14 papers )


2014
by  and
Int. J. Mol. Sci. 2014, 15(8), 14492-14504; doi:10.3390/ijms150814492
Received: 10 July 2014; in revised form: 8 August 2014 / Accepted: 15 August 2014 / Published: 20 August 2014
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2013
by  and
Int. J. Mol. Sci. 2013, 14(12), 23402-23419; doi:10.3390/ijms141223402
Received: 13 September 2013; in revised form: 11 November 2013 / Accepted: 13 November 2013 / Published: 28 November 2013
Show/Hide Abstract | Cited by 3 | PDF Full-text (192 KB) | HTML Full-text | XML Full-text

by ,  and
Int. J. Mol. Sci. 2013, 14(11), 22906-22932; doi:10.3390/ijms141122906
Received: 22 September 2013; in revised form: 13 November 2013 / Accepted: 13 November 2013 / Published: 20 November 2013
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by  and
Int. J. Mol. Sci. 2013, 14(11), 22117-22131; doi:10.3390/ijms141122117
Received: 18 July 2013; in revised form: 21 October 2013 / Accepted: 28 October 2013 / Published: 8 November 2013
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by , , , ,  and
Int. J. Mol. Sci. 2013, 14(11), 21705-21726; doi:10.3390/ijms141121705
Received: 6 September 2013; in revised form: 17 October 2013 / Accepted: 22 October 2013 / Published: 1 November 2013
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by , , , ,  and
Int. J. Mol. Sci. 2013, 14(10), 20256-20281; doi:10.3390/ijms141020256
Received: 29 July 2013; in revised form: 6 September 2013 / Accepted: 16 September 2013 / Published: 11 October 2013
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by ,  and
Int. J. Mol. Sci. 2013, 14(10), 20079-20111; doi:10.3390/ijms141020079
Received: 5 July 2013; in revised form: 13 September 2013 / Accepted: 18 September 2013 / Published: 9 October 2013
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by , ,  and
Int. J. Mol. Sci. 2013, 14(9), 19202-19229; doi:10.3390/ijms140919202
Received: 3 July 2013; in revised form: 17 August 2013 / Accepted: 6 September 2013 / Published: 18 September 2013
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by ,  and
Int. J. Mol. Sci. 2013, 14(9), 18999-19024; doi:10.3390/ijms140918999
Received: 12 August 2013; in revised form: 2 September 2013 / Accepted: 4 September 2013 / Published: 16 September 2013
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by ,  and
Int. J. Mol. Sci. 2013, 14(9), 18009-18023; doi:10.3390/ijms140918009
Received: 25 June 2013; in revised form: 21 August 2013 / Accepted: 26 August 2013 / Published: 3 September 2013
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by , , ,  and
Int. J. Mol. Sci. 2013, 14(8), 17204-17220; doi:10.3390/ijms140817204
Received: 11 July 2013; in revised form: 31 July 2013 / Accepted: 9 August 2013 / Published: 20 August 2013
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by , , ,  and
Int. J. Mol. Sci. 2013, 14(8), 17111-17121; doi:10.3390/ijms140817111
Received: 1 July 2013; in revised form: 5 August 2013 / Accepted: 7 August 2013 / Published: 19 August 2013
Show/Hide Abstract | Cited by 1 | PDF Full-text (208 KB) | HTML Full-text | XML Full-text

by  and
Int. J. Mol. Sci. 2013, 14(8), 16168-16183; doi:10.3390/ijms140816168
Received: 9 July 2013; in revised form: 23 July 2013 / Accepted: 25 July 2013 / Published: 5 August 2013
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by , ,  and
Int. J. Mol. Sci. 2013, 14(8), 15785-15809; doi:10.3390/ijms140815785
Received: 1 July 2013; in revised form: 15 July 2013 / Accepted: 18 July 2013 / Published: 30 July 2013
Show/Hide Abstract | Cited by 1 | PDF Full-text (1033 KB) | HTML Full-text | XML Full-text

by , ,  and
Int. J. Mol. Sci. 2013, 14(5), 9018-9036; doi:10.3390/ijms14059018
Received: 28 January 2013; in revised form: 7 April 2013 / Accepted: 15 April 2013 / Published: 25 April 2013
Show/Hide Abstract | Cited by 1 | PDF Full-text (398 KB) | HTML Full-text | XML Full-text
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Last update: 6 March 2014

Int. J. Mol. Sci. EISSN 1422-0067 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert