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Int. J. Mol. Sci. 2013, 14(5), 9018-9036; doi:10.3390/ijms14059018

Ribonucleoprotein Complexes That Control Circadian Clocks

Key Laboratory of Gene Engineering of the Ministry of Education, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou 510275, China
* Author to whom correspondence should be addressed.
Received: 28 January 2013 / Revised: 7 April 2013 / Accepted: 15 April 2013 / Published: 25 April 2013
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Circadian clocks are internal molecular time-keeping mechanisms that enable organisms to adjust their physiology and behavior to the daily surroundings. Misalignment of circadian clocks leads to both physiological and health impairment. Post-transcriptional regulation and translational regulation of circadian clocks have been extensively investigated. In addition, accumulating evidence has shed new light on the involvement of ribonucleoprotein complexes (RNPs) in the post-transcriptional regulation of circadian clocks. Numerous RNA-binding proteins (RBPs) and RNPs have been implicated in the post-transcriptional modification of circadian clock proteins in different model organisms. Herein, we summarize the advances in the current knowledge on the role of RNP complexes in circadian clock regulation.
Keywords: ribonucleoprotein; circadian clock; transcription; translation; post-transcription ribonucleoprotein; circadian clock; transcription; translation; post-transcription
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Wang, D.; Liang, X.; Chen, X.; Guo, J. Ribonucleoprotein Complexes That Control Circadian Clocks. Int. J. Mol. Sci. 2013, 14, 9018-9036.

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