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Int. J. Mol. Sci. 2013, 14(5), 9018-9036; doi:10.3390/ijms14059018
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Ribonucleoprotein Complexes That Control Circadian Clocks

,
,
 and
*
Key Laboratory of Gene Engineering of the Ministry of Education, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou 510275, China
* Author to whom correspondence should be addressed.
Received: 28 January 2013 / Revised: 7 April 2013 / Accepted: 15 April 2013 / Published: 25 April 2013
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Abstract

Circadian clocks are internal molecular time-keeping mechanisms that enable organisms to adjust their physiology and behavior to the daily surroundings. Misalignment of circadian clocks leads to both physiological and health impairment. Post-transcriptional regulation and translational regulation of circadian clocks have been extensively investigated. In addition, accumulating evidence has shed new light on the involvement of ribonucleoprotein complexes (RNPs) in the post-transcriptional regulation of circadian clocks. Numerous RNA-binding proteins (RBPs) and RNPs have been implicated in the post-transcriptional modification of circadian clock proteins in different model organisms. Herein, we summarize the advances in the current knowledge on the role of RNP complexes in circadian clock regulation.
Keywords: ribonucleoprotein; circadian clock; transcription; translation; post-transcription ribonucleoprotein; circadian clock; transcription; translation; post-transcription
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).
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Wang, D.; Liang, X.; Chen, X.; Guo, J. Ribonucleoprotein Complexes That Control Circadian Clocks. Int. J. Mol. Sci. 2013, 14, 9018-9036.

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