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The Ribonucleoprotein Csr Network
AbstractRibonucleoprotein complexes are essential regulatory components in bacteria. In this review, we focus on the carbon storage regulator (Csr) network, which is well conserved in the bacterial world. This regulatory network is composed of the CsrA master regulator, its targets and regulators. CsrA binds to mRNA targets and regulates translation either negatively or positively. Binding to small non-coding RNAs controls activity of this protein. Expression of these regulators is tightly regulated at the level of transcription and stability by various global regulators (RNAses, two-component systems, alarmone). We discuss the implications of these complex regulations in bacterial adaptation.
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Seyll, E.; Van Melderen, L. The Ribonucleoprotein Csr Network. Int. J. Mol. Sci. 2013, 14, 22117-22131.View more citation formats
Seyll E, Van Melderen L. The Ribonucleoprotein Csr Network. International Journal of Molecular Sciences. 2013; 14(11):22117-22131.Chicago/Turabian Style
Seyll, Ethel; Van Melderen, Laurence. 2013. "The Ribonucleoprotein Csr Network." Int. J. Mol. Sci. 14, no. 11: 22117-22131.