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21 pages, 4909 KiB  
Article
Rapid 3D Camera Calibration for Large-Scale Structural Monitoring
by Fabio Bottalico, Nicholas A. Valente, Christopher Niezrecki, Kshitij Jerath, Yan Luo and Alessandro Sabato
Remote Sens. 2025, 17(15), 2720; https://doi.org/10.3390/rs17152720 (registering DOI) - 6 Aug 2025
Abstract
Computer vision techniques such as three-dimensional digital image correlation (3D-DIC) and three-dimensional point tracking (3D-PT) have demonstrated broad applicability for monitoring the conditions of large-scale engineering systems by reconstructing and tracking dynamic point clouds corresponding to the surface of a structure. Accurate stereophotogrammetry [...] Read more.
Computer vision techniques such as three-dimensional digital image correlation (3D-DIC) and three-dimensional point tracking (3D-PT) have demonstrated broad applicability for monitoring the conditions of large-scale engineering systems by reconstructing and tracking dynamic point clouds corresponding to the surface of a structure. Accurate stereophotogrammetry measurements require the stereo cameras to be calibrated to determine their intrinsic and extrinsic parameters by capturing multiple images of a calibration object. This image-based approach becomes cumbersome and time-consuming as the size of the tested object increases. To streamline the calibration and make it scale-insensitive, a multi-sensor system embedding inertial measurement units and a laser sensor is developed to compute the extrinsic parameters of the stereo cameras. In this research, the accuracy of the proposed sensor-based calibration method in performing stereophotogrammetry is validated experimentally and compared with traditional approaches. Tests conducted at various scales reveal that the proposed sensor-based calibration enables reconstructing both static and dynamic point clouds, measuring displacements with an accuracy higher than 95% compared to image-based traditional calibration, while being up to an order of magnitude faster and easier to deploy. The novel approach has broad applications for making static, dynamic, and deformation measurements to transform how large-scale structural health monitoring can be performed. Full article
(This article belongs to the Special Issue New Perspectives on 3D Point Cloud (Third Edition))
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11 pages, 1259 KiB  
Article
Exploring the Role of MRCP+ for Enhancing Detection of High-Grade Strictures in Primary Sclerosing Cholangitis
by James Franklin, Charlotte Robinson, Carlos Ferreira, Elizabeth Shumbayawonda and Kartik Jhaveri
J. Clin. Med. 2025, 14(15), 5530; https://doi.org/10.3390/jcm14155530 - 6 Aug 2025
Abstract
Background: Identifying high-grade strictures (HGS) in patients with primary sclerosing cholangitis (PSC) relies upon subjective assessments of magnetic resonance cholangiopancreatography (MRCP). Quantitative MRCP (MRCP+) provides objective evaluation of MRCP examinations, which may help make these assessments more consistent and improve patient management and [...] Read more.
Background: Identifying high-grade strictures (HGS) in patients with primary sclerosing cholangitis (PSC) relies upon subjective assessments of magnetic resonance cholangiopancreatography (MRCP). Quantitative MRCP (MRCP+) provides objective evaluation of MRCP examinations, which may help make these assessments more consistent and improve patient management and selection for intervention. We evaluated the impact of MRCP+ on clinicians’ confidence in diagnosing HGS in patients with PSC. Methods: Three expert abdominal radiologists independently assessed 28 patients with PSC. Radiological reads of MRCPs were performed twice, in a random order, three weeks apart, then a third time with MRCP+. HGS presence was recorded on semi-quantitative confidence scales. The cases where readers definitively agreed on presence/absence of HGS were used to assess inter- and intra-reader agreement and confidence. Results: When using MRCP alone, high intra-reader agreement was observed in identifying HGS within both intra- and extrahepatic ducts (64.3% and 70.8%, respectively), while inter-reader agreement was significantly lower for intrahepatic ducts (42.9%) than extrahepatic ducts (66.1%) (p < 0.01). Using MRCP+ in the third read significantly improved inter-reader agreement for intrahepatic HGS detection to 67.9% versus baseline reads (p = 0.02) and was comparable with extrahepatic ducts. Reader confidence tended to increase when supplemented with MRCP+, and inter-reader variability decreased. MRCP+ metrics had good performance in identifying HGS in both extra-hepatic (AUC:0.85) and intra-hepatic ducts (AUC:0.75). Conclusions: MRCP evaluation supported by quantitative metrics tended to increase individual reader confidence and reduce inter-reader variability for detecting HGS. Our results indicate that MRCP+ might help standardize MRCP assessment and subsequent management for patients with PSC. Full article
(This article belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
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25 pages, 502 KiB  
Article
Passing with ChatGPT? Ethical Evaluations of Generative AI Use in Higher Education
by Antonio Pérez-Portabella, Mario Arias-Oliva, Graciela Padilla-Castillo and Jorge de Andrés-Sánchez
Digital 2025, 5(3), 33; https://doi.org/10.3390/digital5030033 - 6 Aug 2025
Abstract
The emergence of generative artificial intelligence (GenAI) in higher education offers new opportunities for academic support while also raising complex ethical concerns. This study explores how university students ethically evaluate the use of GenAI in three academic contexts: improving essay writing, preparing for [...] Read more.
The emergence of generative artificial intelligence (GenAI) in higher education offers new opportunities for academic support while also raising complex ethical concerns. This study explores how university students ethically evaluate the use of GenAI in three academic contexts: improving essay writing, preparing for exams, and generating complete essays without personal input. Drawing on the Multidimensional Ethics Scale (MES), the research assesses five philosophical frameworks—moral equity, relativism, egoism, utilitarianism, and deontology—based on a survey conducted among undergraduate social sciences students in Spain. The findings reveal that students generally view GenAI use as ethically acceptable when used to improve or prepare content, but express stronger ethical concerns when authorship is replaced by automation. Gender and full-time employment status also influence ethical evaluations: women respond differently than men in utilitarian dimensions, while working students tend to adopt a more relativist stance and are more tolerant of full automation. These results highlight the importance of context, individual characteristics, and philosophical orientation in shaping ethical judgments about GenAI use in academia. Full article
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13 pages, 504 KiB  
Article
Fear of Falling After Total Knee Replacement: A Saudi Experience
by Turki Aljuhani, Jayachandran Vetrayan, Mohammed A. Alfayez, Saleh A. Alshehri, Mohmad H. Alsabani, Lafi H. Olayan, Fahdah A. Aljamaan and Abdulaziz O. Alharbi
Clin. Pract. 2025, 15(8), 146; https://doi.org/10.3390/clinpract15080146 - 6 Aug 2025
Abstract
Background: Fear of falling (FOF) is a significant concern among older adults, especially after total knee arthroplasty (TKA). FOF can limit daily activities, reduce quality of life, and hinder recovery. This study aimed to investigate the prevalence, severity, and impacts of FOF [...] Read more.
Background: Fear of falling (FOF) is a significant concern among older adults, especially after total knee arthroplasty (TKA). FOF can limit daily activities, reduce quality of life, and hinder recovery. This study aimed to investigate the prevalence, severity, and impacts of FOF in patients undergoing TKA and identify factors contributing to increased FOF. Methods: A prospective observational study was conducted at King Abdulaziz Medical City in Riyadh, Saudi Arabia, from April 2024 to December 2024. This study included 52 participants aged 20 to 75 years who had undergone primary TKA. Data were collected at two time points: after TKA and at three months post-surgery. The Short Falls Efficacy Scale-International (SFES-I) was used to assess the severity of FOF, and the Short Form 36 (SF-36) was used to measure the quality of life. Descriptive statistics, t-tests, and logistic regression were used for analysis. Results: This study included 52 participants (mean age: 63.77 ± 6.65 years; 82.7% female). Post-TKA, all participants exhibited high FOF (mean SFES-I score: 56.75 ± 8.30). After three months, the mean SFES-I score decreased significantly to 49.04 ± 12.45 (t = 4.408, p < 0.05). Post-TKA, SF-36 showed significant improvements in the physical function, role of physical limitations, bodily pain, vitality, social function, role of emotional limitations, and mental health subdomains. Bilateral total knee arthroplasty, body mass index, and some SF-36 subcomponents—such as general health, vitality, and role of emotional limitations—were identified as factors leading to increased FOF. Conclusions: FOF remains prevalent and severe in TKA patients, even at three months post-surgery, affecting rehabilitation outcomes. Early identification and tailored interventions for FOF should be considered essential components of comprehensive TKA recovery programs. Full article
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27 pages, 5228 KiB  
Article
Detection of Surface Defects in Steel Based on Dual-Backbone Network: MBDNet-Attention-YOLO
by Xinyu Wang, Shuhui Ma, Shiting Wu, Zhaoye Li, Jinrong Cao and Peiquan Xu
Sensors 2025, 25(15), 4817; https://doi.org/10.3390/s25154817 - 5 Aug 2025
Abstract
Automated surface defect detection in steel manufacturing is pivotal for ensuring product quality, yet it remains an open challenge owing to the extreme heterogeneity of defect morphologies—ranging from hairline cracks and microscopic pores to elongated scratches and shallow dents. Existing approaches, whether classical [...] Read more.
Automated surface defect detection in steel manufacturing is pivotal for ensuring product quality, yet it remains an open challenge owing to the extreme heterogeneity of defect morphologies—ranging from hairline cracks and microscopic pores to elongated scratches and shallow dents. Existing approaches, whether classical vision pipelines or recent deep-learning paradigms, struggle to simultaneously satisfy the stringent demands of industrial scenarios: high accuracy on sub-millimeter flaws, insensitivity to texture-rich backgrounds, and real-time throughput on resource-constrained hardware. Although contemporary detectors have narrowed the gap, they still exhibit pronounced sensitivity–robustness trade-offs, particularly in the presence of scale-varying defects and cluttered surfaces. To address these limitations, we introduce MBY (MBDNet-Attention-YOLO), a lightweight yet powerful framework that synergistically couples the MBDNet backbone with the YOLO detection head. Specifically, the backbone embeds three novel components: (1) HGStem, a hierarchical stem block that enriches low-level representations while suppressing redundant activations; (2) Dynamic Align Fusion (DAF), an adaptive cross-scale fusion mechanism that dynamically re-weights feature contributions according to defect saliency; and (3) C2f-DWR, a depth-wise residual variant that progressively expands receptive fields without incurring prohibitive computational costs. Building upon this enriched feature hierarchy, the neck employs our proposed MultiSEAM module—a cascaded squeeze-and-excitation attention mechanism operating at multiple granularities—to harmonize fine-grained and semantic cues, thereby amplifying weak defect signals against complex textures. Finally, we integrate the Inner-SIoU loss, which refines the geometric alignment between predicted and ground-truth boxes by jointly optimizing center distance, aspect ratio consistency, and IoU overlap, leading to faster convergence and tighter localization. Extensive experiments on two publicly available steel-defect benchmarks—NEU-DET and PVEL-AD—demonstrate the superiority of MBY. Without bells and whistles, our model achieves 85.8% mAP@0.5 on NEU-DET and 75.9% mAP@0.5 on PVEL-AD, surpassing the best-reported results by significant margins while maintaining real-time inference on an NVIDIA Jetson Xavier. Ablation studies corroborate the complementary roles of each component, underscoring MBY’s robustness across defect scales and surface conditions. These results suggest that MBY strikes an appealing balance between accuracy, efficiency, and deployability, offering a pragmatic solution for next-generation industrial quality-control systems. Full article
(This article belongs to the Section Sensing and Imaging)
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23 pages, 2235 KiB  
Article
Ternary Historical Memory-Based Robust Clustered Particle Swarm Optimization for Dynamic Berth Allocation and Crane Assignment Problem
by Ruiqi Wu, Shiming Mao and Yi Sun
Mathematics 2025, 13(15), 2516; https://doi.org/10.3390/math13152516 - 5 Aug 2025
Abstract
The berth allocation and crane assignment problem (BACAP) is a key challenge in port logistics, particularly under dynamic and uncertain vessel arrival conditions. To address the limitations of existing methods in handling large-scale and high-disturbance scenarios, this paper proposes a novel optimization framework: [...] Read more.
The berth allocation and crane assignment problem (BACAP) is a key challenge in port logistics, particularly under dynamic and uncertain vessel arrival conditions. To address the limitations of existing methods in handling large-scale and high-disturbance scenarios, this paper proposes a novel optimization framework: Ternary Historical Memory-based Robust Clustered Particle Swarm Optimization (THM-RCPSO). In this method, the initial particle swarm is divided into multiple clusters, each conducting local searches to identify regional optima. These clusters then exchange information to iteratively refine the global best solution. A ternary historical memory mechanism further enhances the optimization by recording and comparing the best solutions from three different strategies, ensuring guidance from historical performance during exploration. Experimental evaluations on 25 dynamic BACAP benchmark instances show that THM-RCPSO achieves the lowest average vessel dwell time in 22 out of 25 cases, with the lowest overall average rank among five tested algorithms. Specifically, it demonstrates significant advantages on large-scale instances with 150 vessels, where it consistently outperforms competing methods such as HRBA, ACO, and GAMCS in both solution quality and robustness. These results confirm THM-RCPSO’s strong capability in solving dynamic and large-scale DBACAP scenarios with high disturbance levels. Full article
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12 pages, 840 KiB  
Article
Baseline Knee Osteoarthritis and Chronic Obstructive Pulmonary Disease as Predictors of Physical Activity Decline: A Five-Year Longitudinal Study in U.S. Adults Using the Disablement Process Framework
by Saad A. Alhammad and Vishal Vennu
Healthcare 2025, 13(15), 1902; https://doi.org/10.3390/healthcare13151902 - 5 Aug 2025
Abstract
Background/Objective: Understanding how chronic conditions such as knee osteoarthritis (OA) and chronic obstructive pulmonary disease (COPD) influence long-term physical activity (PA) is essential for developing condition-specific rehabilitation strategies. This study aimed to examine whether baseline diagnoses of knee OA and COPD are independently [...] Read more.
Background/Objective: Understanding how chronic conditions such as knee osteoarthritis (OA) and chronic obstructive pulmonary disease (COPD) influence long-term physical activity (PA) is essential for developing condition-specific rehabilitation strategies. This study aimed to examine whether baseline diagnoses of knee OA and COPD are independently associated with the trajectories of PA decline over five years in U.S. adults, informed by the disablement process model. Methods: We analyzed data from 855 adults aged ≥45 years enrolled in the Osteoarthritis Initiative (OAI). The participants were categorized into three baseline groups, control (n = 122), knee OA (n = 646), and COPD (n = 87), based on self-reports and prior clinical assessments. PA was measured annually for five years using the Physical Activity Scale for the Elderly (PASE). General linear mixed models assessed changes in PA over time, adjusting for demographic, behavioral, and clinical covariates. Results: Compared to the controls, participants with knee OA had a significant decline in PA over time (β = −6.62; 95% CI: −15.4 to −2.19; p = 0.014). Those with COPD experienced an even greater decline compared to the knee OA group (β = −11.2; 95% CI: −21.7 to −0.67; p = 0.037). These associations persisted after adjusting for age, sex, body mass index, comorbidities, and smoking. Conclusions: Baseline knee OA and COPD were independently associated with long-term reductions in PA. These findings underscore the importance of early, tailored rehabilitation strategies, particularly pulmonary rehabilitation, in preserving functional independence among older adults with chronic conditions. Full article
(This article belongs to the Special Issue Association Between Physical Activity and Chronic Condition)
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17 pages, 12216 KiB  
Article
Green/Blue Initiatives as a Proposed Intermediate Step to Achieve Nature-Based Solutions for Wildfire Risk Management
by Stella Schroeder and Carolina Ojeda Leal
Fire 2025, 8(8), 307; https://doi.org/10.3390/fire8080307 - 5 Aug 2025
Abstract
Implementing nature-based solutions (NbSs) for wildfire risk management and other hazards has been challenging in emerging economies due to the high costs, the lack of immediate returns on investment, and stringent inclusion criteria set by organizations like the IUCN and domain experts. To [...] Read more.
Implementing nature-based solutions (NbSs) for wildfire risk management and other hazards has been challenging in emerging economies due to the high costs, the lack of immediate returns on investment, and stringent inclusion criteria set by organizations like the IUCN and domain experts. To address these challenges, this exploratory study proposes a new concept: green/blue initiatives. These initiatives represent intermediate steps, encompassing small-scale, community-driven activities that can evolve into recognized NbSs over time. To explore this concept, experiences related to wildfire prevention in the Biobío region of Chile were analyzed through primary and secondary source reviews. The analysis identified three initiatives qualifying as green/blue initiatives: (1) goat grazing in Santa Juana to reduce fuel loads, (2) a restoration prevention farm model in Florida called Faro de Restauración Mahuidanche and (3) the Conservation Landscape Strategy in Nonguén. They were examined in detail using data collected from site visits and interviews. In contrast to Chile’s prevailing wildfire policies, which focus on costly, large-scale fire suppression efforts, these initiatives emphasize the importance of reframing wildfire as a manageable ecological process. Lastly, the challenges and enabling factors for adopting green/blue initiatives are discussed, highlighting their potential to pave the way for future NbS implementation in central Chile. Full article
(This article belongs to the Special Issue Nature-Based Solutions to Extreme Wildfires)
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20 pages, 1971 KiB  
Article
FFG-YOLO: Improved YOLOv8 for Target Detection of Lightweight Unmanned Aerial Vehicles
by Tongxu Wang, Sizhe Yang, Ming Wan and Yanqiu Liu
Appl. Syst. Innov. 2025, 8(4), 109; https://doi.org/10.3390/asi8040109 - 4 Aug 2025
Abstract
Target detection is essential in intelligent transportation and autonomous control of unmanned aerial vehicles (UAVs), with single-stage detection algorithms used widely due to their speed. However, these algorithms face limitations in detecting small targets, especially in aerial photography from unmanned aerial vehicles (UAVs), [...] Read more.
Target detection is essential in intelligent transportation and autonomous control of unmanned aerial vehicles (UAVs), with single-stage detection algorithms used widely due to their speed. However, these algorithms face limitations in detecting small targets, especially in aerial photography from unmanned aerial vehicles (UAVs), where small targets are often occluded, multi-scale semantic information is easily lost, and there is a trade-off between real-time processing and computational resources. Existing algorithms struggle to effectively extract multi-dimensional features and deep semantic information from images and to balance detection accuracy with model complexity. To address these limitations, we developed FFG-YOLO, a lightweight small-target detection method for UAVs based on YOLOv8. FFG-YOLO incorporates three modules: a feature enhancement block (FEB), a feature concat block (FCB), and a global context awareness block (GCAB). These modules strengthen feature extraction from small targets, resolve semantic bias in multi-scale feature fusion, and help differentiate small targets from complex backgrounds. We also improved the positioning accuracy of small targets using the Wasserstein distance loss function. Experiments showed that FFG-YOLO outperformed other algorithms, including YOLOv8n, in small-target detection due to its lightweight nature, meeting the stringent real-time performance and deployment requirements of UAVs. Full article
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9 pages, 206 KiB  
Article
Examining the Relationship Between Balance and Functional Status in the Geriatric Population
by Eleni Vermisso, Effrosyni Stamou, Garyfallia Tsichli, Ioanna Foteinou and Anna Christakou
Med. Sci. 2025, 13(3), 110; https://doi.org/10.3390/medsci13030110 - 2 Aug 2025
Viewed by 184
Abstract
Background/Objectives: Aging is associated with a gradual decline in physical capabilities, often leading to impaired balance and reduced functional status, which are major contributors to falls in older adults. Although many studies have assessed these variables independently, a limited amount of research has [...] Read more.
Background/Objectives: Aging is associated with a gradual decline in physical capabilities, often leading to impaired balance and reduced functional status, which are major contributors to falls in older adults. Although many studies have assessed these variables independently, a limited amount of research has explored the direct relationship between balance and functional status in a healthy geriatric population. The aim of this study was to investigate the relationship between balance and functional capacity and to assess the influence of demographic factors such as age, comorbidities, smoking status, and history of falls. Methods: A sample of community-dwelling older adults (19 women, 16 men) (n = 35), aged 60 years and above (M = 78 years; SD = 9.23) from Sparta, Greece, took part in the present study. Participants were assessed using three validated tools: (a) the Five Times Sit-to-Stand test, (b) the Timed Up-and-Go test, and (c) the Berg Balance Scale. Spearman’s rank correlation coefficient was used for statistical analysis (α = 0.05). Results: Age was positively correlated with poorer performance in the Five Times Sit-to-Stand (r = 0.40; p < 0.01) and the Timed Up-and-Go test (r = 0.47; p < 0.01) and negatively correlated with Berg Balance Scale scores (r = −0.51; p < 0.01). Comorbidities and smoking were also associated with the Berg Balance Scale. A strong negative correlation was observed between balance and the other two functional tests (Five Times Sit-to-Stand: r = −0.51; Timed Up-and-Go: r = −0.66; both p < 0.01). Conclusions: The findings highlight the importance of evaluating both balance and functional capacity in older adults as interrelated factors that can significantly influence quality of life and fall risk. Future research with larger and more diverse populations is recommended to confirm the present findings and to use exercise programs to prevent falls in the geriatric population. Full article
36 pages, 699 KiB  
Article
A Framework of Indicators for Assessing Team Performance of Human–Robot Collaboration in Construction Projects
by Guodong Zhang, Xiaowei Luo, Lei Zhang, Wei Li, Wen Wang and Qiming Li
Buildings 2025, 15(15), 2734; https://doi.org/10.3390/buildings15152734 - 2 Aug 2025
Viewed by 274
Abstract
The construction industry has been troubled by a shortage of skilled labor and safety accidents in recent years. Therefore, more and more robots are introduced to undertake dangerous and repetitive jobs, so that human workers can concentrate on higher-value and creative problem-solving tasks. [...] Read more.
The construction industry has been troubled by a shortage of skilled labor and safety accidents in recent years. Therefore, more and more robots are introduced to undertake dangerous and repetitive jobs, so that human workers can concentrate on higher-value and creative problem-solving tasks. Nevertheless, although human–robot collaboration (HRC) shows great potential, most existing evaluation methods still focus on the single performance of either the human or robot, and systematic indicators for a whole HRC team remain insufficient. To fill this research gap, the present study constructs a comprehensive evaluation framework for HRC team performance in construction projects. Firstly, a detailed literature review is carried out, and three theories are integrated to build 33 indicators preliminarily. Afterwards, an expert questionnaire survey (N = 15) is adopted to revise and verify the model empirically. The survey yielded a Cronbach’s alpha of 0.916, indicating excellent internal consistency. The indicators rated highest in importance were task completion time (µ = 4.53) and dynamic separation distance (µ = 4.47) on a 5-point scale. Eight indicators were excluded due to mean importance ratings falling below the 3.0 threshold. The framework is formed with five main dimensions and 25 concrete indicators. Finally, an AHP-TOPSIS method is used to evaluate the HRC team performance. The AHP analysis reveals that Safety (weight = 0.2708) is prioritized over Productivity (weight = 0.2327) by experts, establishing a safety-first principle for successful HRC deployment. The framework is demonstrated through a case study of a human–robot plastering team, whose team performance scored as fair. This shows that the framework can help practitioners find out the advantages and disadvantages of HRC team performance and provide targeted improvement strategies. Furthermore, the framework offers construction managers a scientific basis for deciding robot deployment and team assignment, thus promoting safer, more efficient, and more creative HRC in construction projects. Full article
(This article belongs to the Section Construction Management, and Computers & Digitization)
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41 pages, 86958 KiB  
Article
An Efficient Aerial Image Detection with Variable Receptive Fields
by Wenbin Liu, Liangren Shi and Guocheng An
Remote Sens. 2025, 17(15), 2672; https://doi.org/10.3390/rs17152672 - 2 Aug 2025
Viewed by 364
Abstract
This article presents VRF-DETR, a lightweight real-time object detection framework for aerial remote sensing images, aimed at addressing the challenge of insufficient receptive fields for easily confused categories due to differences in height and perspective. Based on the RT-DETR architecture, our approach introduces [...] Read more.
This article presents VRF-DETR, a lightweight real-time object detection framework for aerial remote sensing images, aimed at addressing the challenge of insufficient receptive fields for easily confused categories due to differences in height and perspective. Based on the RT-DETR architecture, our approach introduces three key innovations: the multi-scale receptive field adaptive fusion (MSRF2) module replaces the Transformer encoder with parallel dilated convolutions and spatial-channel attention to adjust receptive fields for confusing objects dynamically; the gated multi-scale context (GMSC) block reconstructs the backbone using Gated Multi-Scale Context units with attention-gated convolution (AGConv), reducing parameters while enhancing multi-scale feature extraction; and the context-guided fusion (CGF) module optimizes feature fusion via context-guided weighting to resolve multi-scale semantic conflicts. Evaluations were conducted on both the VisDrone2019 and UAVDT datasets, where VRF-DETR achieved the mAP50 of 52.1% and the mAP50-95 of 32.2% on the VisDrone2019 validation set, surpassing RT-DETR by 4.9% and 3.5%, respectively, while reducing parameters by 32% and FLOPs by 22%. It maintains real-time performance (62.1 FPS) and generalizes effectively, outperforming state-of-the-art methods in accuracy-efficiency trade-offs for aerial object detection. Full article
(This article belongs to the Special Issue Deep Learning Innovations in Remote Sensing)
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13 pages, 241 KiB  
Article
The Pivotal Role of Social Support, Self-Compassion and Self-Care in Predicting Physical and Mental Health Among Mothers of Young Children
by Shiran Bord, Liron Inchi, Yuval Paldi, Ravit Baruch, Miriam Schwartz Shpiro, Shani Ronen, Limor Eizenberg, Ilana Gens and Maya Yaari
Healthcare 2025, 13(15), 1889; https://doi.org/10.3390/healthcare13151889 - 1 Aug 2025
Viewed by 220
Abstract
Background: Mothers’ health significantly affects their well-being and that of their families. The early years of motherhood can be tough and impact mental health. This study examined the associations between mothers’ self-compassion, social support, and self-care behaviors and their physical and mental well-being. [...] Read more.
Background: Mothers’ health significantly affects their well-being and that of their families. The early years of motherhood can be tough and impact mental health. This study examined the associations between mothers’ self-compassion, social support, and self-care behaviors and their physical and mental well-being. Methods: In August 2023, an online cross-sectional survey was conducted among 514 Israeli mothers with children under three. Mothers’ physical and mental health was assessed using SF12. Self-compassion was measured by the Self-Compassion Scale (SCS). Social support was evaluated through the Multidimensional Scale of Perceived Social Support (MSPSS), and self-care was assessed via the Pittsburgh Enjoyable Activities Test (PEAT). Results: Respondents’ average age was 31.5 years. Their self-reported physical health was relatively high, with a mean of 78.36 (SD = 21) on a 0–100 scale (n = 442). Mental health scores were lower, with a mean of 65.88 (SD = 20.28, n = 401). Perceived physical health was higher among Jewish mothers, younger mothers, and those with higher income levels. Additionally, greater social support and self-compassion correlated with better perceived physical health (Adj R2 = 0.11, p < 0.001). For mental health, higher scores were observed among Jewish mothers, younger mothers, and full-time employed mothers. Furthermore, higher social support, self-compassion, and self-care practices were associated with improved perceptions of mental health (Adj R2 = 0.39, p < 0.001). Conclusions: Promoting the well-being of mothers is crucial for their health, their children’s well-being, and the family unit. Health professionals working with mothers of young children should emphasize and help promote social support, self-compassion, and self-care activities. Full article
21 pages, 5734 KiB  
Article
Analytical Inertia Identification of Doubly Fed Wind Farm with Limited Control Information Based on Symbolic Regression
by Mengxuan Shi, Yang Li, Xingyu Shi, Dejun Shao, Mujie Zhang, Duange Guo and Yijia Cao
Appl. Sci. 2025, 15(15), 8578; https://doi.org/10.3390/app15158578 (registering DOI) - 1 Aug 2025
Viewed by 109
Abstract
The integration of large-scale wind power clusters significantly reduces the inertia level of the power system, increasing the risk of frequency instability. Accurately assessing the equivalent virtual inertia of wind farms is critical for grid stability. Addressing the dual bottlenecks in existing inertia [...] Read more.
The integration of large-scale wind power clusters significantly reduces the inertia level of the power system, increasing the risk of frequency instability. Accurately assessing the equivalent virtual inertia of wind farms is critical for grid stability. Addressing the dual bottlenecks in existing inertia assessment methods, where physics-based modeling requires full control transparency and data-driven approaches lack interpretability for inertia response analysis, thus failing to reconcile commercial confidentiality constraints with analytical needs, this paper proposes a symbolic regression framework for inertia evaluation in doubly fed wind farms with limited control information constraints. First, a dynamic model for the inertia response of DFIG wind farms is established, and a mathematical expression for the equivalent virtual inertia time constant under different control strategies is derived. Based on this, a nonlinear function library reflecting frequency-active power dynamic is constructed, and a symbolic regression model representing the system’s inertia response characteristics is established by correlating operational data. Then, sparse relaxation optimization is applied to identify unknown parameters, allowing for the quantification of the wind farm’s equivalent virtual inertia. Finally, the effectiveness of the proposed method is validated in an IEEE three-machine nine-bus system containing a doubly fed wind power cluster. Case studies show that the proposed method can fully utilize prior model knowledge and operational data to accurately assess the system’s inertia level with low computational complexity. Full article
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24 pages, 3243 KiB  
Article
Design of Experiments Leads to Scalable Analgesic Near-Infrared Fluorescent Coconut Nanoemulsions
by Amit Chandra Das, Gayathri Aparnasai Reddy, Shekh Md. Newaj, Smith Patel, Riddhi Vichare, Lu Liu and Jelena M. Janjic
Pharmaceutics 2025, 17(8), 1010; https://doi.org/10.3390/pharmaceutics17081010 - 1 Aug 2025
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Abstract
Background: Pain is a complex phenomenon characterized by unpleasant experiences with profound heterogeneity influenced by biological, psychological, and social factors. According to the National Health Interview Survey, 50.2 million U.S. adults (20.5%) experience pain on most days, with the annual cost of prescription [...] Read more.
Background: Pain is a complex phenomenon characterized by unpleasant experiences with profound heterogeneity influenced by biological, psychological, and social factors. According to the National Health Interview Survey, 50.2 million U.S. adults (20.5%) experience pain on most days, with the annual cost of prescription medication for pain reaching approximately USD 17.8 billion. Theranostic pain nanomedicine therefore emerges as an attractive analgesic strategy with the potential for increased efficacy, reduced side-effects, and treatment personalization. Theranostic nanomedicine combines drug delivery and diagnostic features, allowing for real-time monitoring of analgesic efficacy in vivo using molecular imaging. However, clinical translation of these nanomedicines are challenging due to complex manufacturing methodologies, lack of standardized quality control, and potentially high costs. Quality by Design (QbD) can navigate these challenges and lead to the development of an optimal pain nanomedicine. Our lab previously reported a macrophage-targeted perfluorocarbon nanoemulsion (PFC NE) that demonstrated analgesic efficacy across multiple rodent pain models in both sexes. Here, we report PFC-free, biphasic nanoemulsions formulated with a biocompatible and non-immunogenic plant-based coconut oil loaded with a COX-2 inhibitor and a clinical-grade, indocyanine green (ICG) near-infrared fluorescent (NIRF) dye for parenteral theranostic analgesic nanomedicine. Methods: Critical process parameters and material attributes were identified through the FMECA (Failure, Modes, Effects, and Criticality Analysis) method and optimized using a 3 × 2 full-factorial design of experiments. We investigated the impact of the oil-to-surfactant ratio (w/w) with three different surfactant systems on the colloidal properties of NE. Small-scale (100 mL) batches were manufactured using sonication and microfluidization, and the final formulation was scaled up to 500 mL with microfluidization. The colloidal stability of NE was assessed using dynamic light scattering (DLS) and drug quantification was conducted through reverse-phase HPLC. An in vitro drug release study was conducted using the dialysis bag method, accompanied by HPLC quantification. The formulation was further evaluated for cell viability, cellular uptake, and COX-2 inhibition in the RAW 264.7 macrophage cell line. Results: Nanoemulsion droplet size increased with a higher oil-to-surfactant ratio (w/w) but was no significant impact by the type of surfactant system used. Thermal cycling and serum stability studies confirmed NE colloidal stability upon exposure to high and low temperatures and biological fluids. We also demonstrated the necessity of a solubilizer for long-term fluorescence stability of ICG. The nanoemulsion showed no cellular toxicity and effectively inhibited PGE2 in activated macrophages. Conclusions: To our knowledge, this is the first instance of a celecoxib-loaded theranostic platform developed using a plant-derived hydrocarbon oil, applying the QbD approach that demonstrated COX-2 inhibition. Full article
(This article belongs to the Special Issue Quality by Design in Pharmaceutical Manufacturing)
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