Search Results (21)

The Charpy impact toughness of single-phase austenitic Fe-32Mn-0.6C steel was systematically investigated across a wide temperature spectrum from 25 °C to −196 °C using Charpy V-notch impact tests. The material exhibited a remarkable temperature dependence of impact energy, decreasing dramatically from 120 J at ambient temperature (25 °C) to 13 J under cryogenic conditions (−196 °C). Notably, a steep transition in impact energy occurred within the critical temperature window of −100 °C to −150 °C. Microstructural analysis revealed that synergistic effects of high strain rates and low temperatures significantly restrict dislocation slip and multiplication mechanisms, while also suppressing deformation twinning activation. This restricted plasticity accommodation mechanism fundamentally differs from the deformation characteristics reported in conventional low-carbon high-manganese steels and other face-centered cubic (FCC) alloy systems. Full article

Transition metal selenides are considered one of the most promising materials for sodium-ion battery anodes due to their excellent theoretical capacity. However, it remains challenging to suppress the volume variation and the resulted capacity decay during the charge–discharge process. Herein, hollow-structured CoNiSe₂ dual transition metal selenides wrapped in a carbon shell (HS-Co_xNi_ySe₂@C) were deliberately designed and prepared through sequential coating of polyacrylonitrile (PAN), ion exchange of ZIF-67 with Ni²⁺ metal ions, and carbonization/selenization. The hollow structure was evidenced by transmission electron microscopy, and the crystalline structure was confirmed by X-ray diffraction. The ample internal space of HS-Co_xNi_ySe₂@C effectively accommodated volume expansion during the charge and discharge processes, and the large surface area enabled sufficient contact between the electrode and electrolyte and shortened the diffusion path of sodium ions for a feasible electrochemical reaction. The surface area and ionic conductivity of HS-Co_xNi_ySe₂@C were strongly dependent on the ratio of Co to Ni. The synergistic effect between Co and Ni enhanced the conductivity and electron mobility of HS-Co_xNi_ySe₂@C, thereby improving charge transfer efficiency. By taking into account the structural advantages and rational metal selenide ratios, significant improvements can be achieved in the cycling performance, rate performance, and overall electrochemical stability of sodium-ion batteries. The optimized HS-Co_xNi_ySe₂@C demonstrated excellent performance, and the reversible capacity remained at 334 mAh g⁻¹ after 1000 cycles at a high current of 5.0 A g⁻¹. Full article

Poly(D,L-lactide-co-glycolide) (PLGA) has emerged as a cornerstone in the development of advanced drug delivery systems, particularly for intranasal and pulmonary routes. Its biodegradability, biocompatibility, and adaptability make it an ideal platform for addressing challenges associated with conventional therapies. By enabling sustained and controlled drug release, PLGA formulations reduce dosing frequency, improve patient compliance, and enhance therapeutic efficacy. These systems demonstrate versatility, accommodating hydrophilic and hydrophobic drugs, biological molecules, and co-delivery of synergistic agents. Moreover, surface modifications and advanced preparation techniques enhance targeting, bioavailability, and stability, expanding PLGA’s applications to treat complex diseases such as tuberculosis, cancer, pulmonary fibrosis, and CNS disorders. This manuscript provides an in-depth review of PLGA’s materials, properties, preparation methods, and therapeutic applications, alongside a critical evaluation of challenges and future opportunities in this field. Full article

The significance of knowledge management in the tourism accommodation sector is increasingly vital due to rapid market changes and intense competition. Although the value of identifying and implementing critical success factors (CSFs) for knowledge management is widely recognized in the sector, there is still a lack of comprehensive understanding and practical application of these factors. This study employs the decision-making trial and evaluation laboratory (DEMATEL) methodology to systematically identify and analyze the interrelationships among these CSFs. The findings reveal a complex web of dependencies within this network. Specifically, leadership commitment and support is identified as the most influential CSF, acting as a fundamental element that enables the successful adoption and integration of knowledge management initiatives. Additionally, strategic alignment and a supportive organizational culture are crucial, working synergistically to ensure that knowledge management initiatives are aligned with overarching organizational goals and create an environment that encourages change and collaboration. Furthermore, the study highlights a mutually reinforcing relationship between knowledge processes, governance, and employee training. This relationship suggests that strong governance structures and clearly defined knowledge processes facilitate and improve the effectiveness of employee training programs while also creating a continuous improvement cycle where improved training further refines governance and knowledge processes. Moreover, the study highlights the integration of the ISO 30401:2018 standard as a systematic framework to support these CSFs, providing a structured approach to improve knowledge management systems. By mapping the cause-and-effect relationships among the identified CSFs, this research offers practical insights for industry professionals to effectively prioritize and address these factors. Full article

With the advancement of high-integration and high-density interconnection in chip manufacturing and packaging, Cu bumping technology in wafer- and panel- level packaging is developed to micrometer-sized structures and pitches to accommodate increased I/O numbers on high-end integrated circuits. Driven by this industrial demand, significant efforts have been dedicated to Cu electroplating techniques for improved pillar shape control and solder joint reliability, which substantially depend on additive formulations and electroplating parameters that regulate the growth morphology, crystal structure, and impurity incorporation in the process of electrodeposition. It is necessary to investigate the effect of an additive on Cu pillar electrodeposition, and to explore the Kirkendall voids formed during the reflowing process, which may result from the additive-induced impurity in the electrodeposited Cu pillars. In this work, a self-synthesized polyquaterntum (PQ) was made out with dual suppressor and leveler effects, and was combined with prototypical accelerator bis- (sodium sulfopropyl)-disulfide (SPS) for patterned Cu pillar electroplating. Then, Sn96.5/Ag3.0/Cu0.5 (SAC305) solder paste were screen printed on electroplated Cu pillars and undergo reflow soldering. Kirkendall voids formed at the joint interfaces were observed and quantified by SEM. Finally, XRD, and EBSD were employed to characterize the microstructure under varying conditions. The results indicate that PQ exhibits significant suppressive and levelled properties with the new structure of both leveler and suppressor. However, its effectiveness is dependent on liquid convection. PQ and SPS work synergistically, influencing the polarization effect in various convective environments. Consequently, uneven adsorption occurs on the surface of the Cu pillars, which results in more Kirkendall voids at the corners than at the center along the Cu pillar surface. Full article

In recent years, the integration of artificial intelligence (AI) into logistics optimization has gained significant attention, particularly concerning sustainability criteria. This article provides an overview of the diverse AI models and algorithms employed in logistics optimization, with a focus on sustainable practices. The discussion covers several techniques, including generative models, machine learning methods, metaheuristic algorithms, and their synergistic combinations with traditional optimization and simulation methods. By employing AI capabilities, logistics stakeholders can enhance decision-making processes, optimize resource utilization, and minimize environmental impacts. Moreover, this paper identifies and analyzes prominent challenges within sustainable logistics, such as reducing carbon emissions, minimizing waste generation, and optimizing transportation routes while considering ecological factors. Furthermore, the paper explores emerging trends in AI-driven logistics optimization, such as the integration of real-time data analytics, blockchain technology, and autonomous systems, which hold immense potential for enhancing efficiency and sustainability. Finally, the paper outlines future research directions, emphasizing the need for further exploration of hybrid AI approaches, robust optimization frameworks, and scalable solutions that accommodate dynamic and uncertain logistics environments. Full article

With the increasing of renewable energy penetration rate in power source structure, the impact of its uncertainty on the stability of the power system is becoming increasingly apparent. The power system faces dual pressures of ensuring power supply and renewable energy accommodation. The way in which to accurately plan the power structure under situations with a high renewable energy penetration rate has become an urgent issue for future power infrastructure upgrading. In this paper, a rational power structure model was proposed for a provincial power grid by iteratively optimizing variables. The synergistic relationship between renewable energy, traditional power sources, and the energy storage system was considered comprehensively and calculated through the time-series production simulation method. The as-proposed model was studied using a scenario of a provincial grid plan in the year 2035. The power balance, electricity consumption, and renewable energy utilization were systematically analyzed, providing an important theoretical basis for the optimization and upgrading of provincial power systems under the rapid growth of renewable energy. Full article

Interest in protein engineering for the enzymatic production of valuable products, such as pharmaceutical compounds and biofuels, is growing rapidly. The cold-active acetyl xylan esterase from Paenibacillus sp. (PbAcE) presents unusually broad substrate specificity. Here, we engineered a hydrophobic substrate-binding pocket to enable the accommodation of relatively large alcohol substrates, such as linalyl acetate and α-terpinyl acetate. To identify candidate residues for engineering, we performed covalent docking of substrates to the Ser185 active site using the HCovDock program. Functional hotspots were analyzed using HotSpot Wizard 3.1. Lys91, His93, and Tyr182 were selected for site-saturation mutagenesis (SSM). After generating the SSM mutant library, a qualitative colorimetric assay was conducted to identify positive mutants. Three, two, and five single mutants were selected for Lys91, His93, and Tyr182, respectively. The best single mutants were then sequentially combined to generate double and triple mutants. Single mutants exhibited a 10–30% increase in activity compared to that of wild-type PbAcE, while no significant synergistic improvements were observed in the double and triple mutants. The increase in activity against both linalyl acetate and α-terpinyl acetate was similar. Mutation did not affect the acetyl binding and catalysis. Further research on the acetyl binding pocket will provide insights into substrate specificity and aid in efficient biocatalyst development for industrial applications. Full article

Assessing mobility in daily life can provide significant insights into several clinical conditions, such as Chronic Obstructive Pulmonary Disease (COPD). In this paper, we present a comprehensive analysis of wearable devices’ performance in gait speed estimation and explore optimal device combinations for everyday use. Using data collected from smartphones, smartwatches, and smart shoes, we evaluated the individual capabilities of each device and explored their synergistic effects when combined, thereby accommodating the preferences and possibilities of individuals for wearing different types of devices. Our study involved 20 healthy subjects performing a modified Six-Minute Walking Test (6MWT) under various conditions. The results revealed only little performance differences among devices, with the combination of smartwatches and smart shoes exhibiting superior estimation accuracy. Particularly, smartwatches captured additional health-related information and demonstrated enhanced accuracy when paired with other devices. Surprisingly, wearing all devices concurrently did not yield optimal results, suggesting a potential redundancy in feature extraction. Feature importance analysis highlighted key variables contributing to gait speed estimation, providing valuable insights for model refinement. Full article

In light of the recent announcement of the primary construction objectives of the modern energy system during the “14th Five-Year Plan”, the renewable energy industry has experienced rapid growth. The accurate assessment of the effects of renewable energy accommodation driven by various factors under the synergistic influence of “Source-Grid-Load-Storage” is vital for guiding the scientific planning and rational arrangement of the future energy system. For this purpose, this paper comprehensively considers boundary conditions such as power demand, load characteristics, cross-regional transmission characteristics, renewable energy resources and output characteristics, as well as energy storage characteristics. Based on the principle of simulation of time series production, this paper establishes a model for evaluating renewable energy accommodation and introduces a continuous optimization solution method. Taking the renewable energy accommodation of the power grid in a Chinese region as a case, this paper constructs 16 representative scenes that satisfy the development plans of various factors in the region. In conjunction with the simulation results of these 16 scenes, this paper uses the Shapley value method to determine the increased accommodation capacity of renewable energy promoted by multiple factors under the synergistic effect. The analysis results show that the Shapley value method examines the entire development process from the current situation to the synergistic scenes. By comprehensively weighing all development scenes regarding the increased accommodation capacity of various factors, this paper quantifies the effects of each factor under the synergistic scenes. Full article

Heteroatom doping is considered an effective method to substantially improve the electrochemical performance of Ti₃C₂T_x MXene for supercapacitors. Herein, a facile and controllable strategy, which combines heat treatment with phosphorous (P) doping by using sodium phosphinate (NaH₂PO₂) as a phosphorus source, is used to modify Ti₃C₂T_x. The intercalated ions from NaH₂PO₂ act as “pillars” to expand the interlayer space of MXene, which is conducive to electrolyte ion diffusion. On the other hand, P doping tailors the surface electronic state of MXene, optimizing electronic conductivity and reducing the free energy of H⁺ diffusion on the MXene surface. Meanwhile, P sites with lower electronegativity owning good electron donor characteristics are easy to share electrons with H⁺, which is beneficial to charge storage. Moreover, the adopted heat treatment replaces –F terminations with O-containing groups, which enhances the hydrophilicity and provides sufficient active sites. The change in surface functional groups increases the content of high valence-stated Ti with a high electrochemical activity that can accommodate more electrons during discharge. Synergistic modification of interlayer structure and chemical state improves the possibility of Ti₃C₂T_x for accommodating more H⁺ ions. Consequently, the modified electrode delivers a specific capacitance of 510 F g⁻¹ at 2 mV s⁻¹, and a capacitance retention of 90.2% at 20 A g⁻¹ after 10,000 cycles. The work provides a coordinated strategy for the rational design of high-capacitance Ti₃C₂T_x MXene electrodes. Full article

One of the crucial challenges of our time is to effectively use metal and metal oxide nanoparticles (NPs) as an alternative way to combat drug-resistant infections. Metal and metal oxide NPs such as Ag, Ag₂O, Cu, Cu₂O, CuO, and ZnO have found their way against antimicrobial resistance. However, they also suffer from several limitations ranging from toxicity issues to resistance mechanisms by complex structures of bacterial communities, so-called biofilms. In this regard, scientists are urgently looking for convenient approaches to develop heterostructure synergistic nanocomposites which could overcome toxicity issues, enhance antimicrobial activity, improve thermal and mechanical stability, and increase shelf life. These nanocomposites provide a controlled release of bioactive substances into the surrounding medium, are cost effective, reproducible, and scalable for real life applications such as food additives, nanoantimicrobial coating in food technology, food preservation, optical limiters, the bio medical field, and wastewater treatment application. Naturally abundant and non-toxic Montmorillonite (MMT) is a novel support to accommodate NPs, due to its negative surface charge and control release of NPs and ions. At the time of this review, around 250 articles have been published focusing on the incorporation of Ag-, Cu-, and ZnO-based NPs into MMT support and thus furthering their introduction into polymer matrix composites dominantly used for antimicrobial application. Therefore, it is highly relevant to report a comprehensive review of Ag-, Cu-, and ZnO-modified MMT. This review provides a comprehensive overview of MMT-based nanoantimicrobials, particularly dealing with preparation methods, materials characterization, and mechanisms of action, antimicrobial activity on different bacterial strains, real life applications, and environmental and toxicity issues. Full article

As a new engine of urban development, the high-speed rail (HSR) station area is an emerging location where the service industry is concentrated. This study aims to reflect the development of accommodation facilities in transport hub areas through the spatial distribution and agglomeration characteristics of the lodging industry in HSR station areas. HSR stations in Beijing, Tianjin, Nanjing, Jinan, Kunshan, and Xuzhou are selected. The Geodetector model is applied to analyze the pertinent driving factors. The findings indicate that: (1) The smaller the population size of the city, the closer the high agglomeration area of the accommodation industry in the HSR station area is to the HSR station. (2) The longer the HSR station is open, the stronger the agglomeration intensity of the accommodation industry is. (3) At HSR stations in various cities, the driving factors affecting the accommodation industry are heterogeneous. The interaction between the factors has a synergistic enhancement effect. Full article

60NiTi alloys have a tremendous potential to be used in aerospace, marine and automotive industries. There is still a need to further improve the deformability due to the high brittleness of the previously prepared 60NiTi. In this work, 200 °C hot silicone oil was selected as the quenching medium for 60NiTi for the first time to overcome its high brittleness. It is found that the unique microstructure of 60NiTi quenched by hot oil has a lamellar structure composed of a channel-like NiTi matrix and lenticular Ni₄Ti₃ phase containing a nano-lath NiTi phase. The 60NiTi exhibits a high compression fracture strain of 10% and large reversible strain of 7.5%; which originates from the superelastic behavior of the NiTi SMA constituent. Upon loading, the R phase reorientation releases the stress concentration at the initial stage; while the stress-induced martensitic transformation accommodates the large elastic deformation of the Ni₄Ti₃ phase at the later stage. This synergistic effect of the two promotes the compressive deformability. Full article

Currently, hyperlipidemia is a growing health issue that is considered a risk factor for obesity. Controlling body weight and modifying life style in most of cases are not adequate and the condition requires medical treatment. Statin drugs (mainly Atorvastatin (ATO)), have been used broadly and for long time as medications for handling higher levels of lipid, especially bad cholesterol, which accordingly controls the prevalence of obesity. Still, the obstacle that stands in front of any formulation is the poor solubility of the drug. Low solubility of ATO came up with poor absorption as well as poor bioavailability. This paved the way for the present study, which aimed to exploit nanotechnology and develop certain nanolipid carriers that could accommodate hydrophobic drugs, such as ATO. Nanostructured lipid carrier (NLC) containing ATO was fabricated using olive oil. Olive oil is natural plant oil possessing confirmed hypolipidemic activity that would help in improving the efficacy of the formulation. Via applying the Quality by Design (QbD) approach, one NLC formula was selected to be optimized based on appropriate size and higher entrapment. Optimized ATO-NLC was scrutinized for zeta potential, in vitro study and kinetic profile. Moreover, stability testing and in vivo hypolipidemic behavior was conducted. The optimized NLC formulation seemed to show particle size (254.23 nm) with neutral zeta potential (−1.77 mV) and entrapment efficiency (69.56%). The formulation could be prolonged for 12 h and provided higher % of release (97.17%). Stability testing confirmed the role of modifying the surface of the formulation with PEG-DSPE in providing a highly stable formulation that could withstand three months storage in two altered conditions. Ultimately, optimized ATO-NLC could successfully lower total cholesterol level in rats induced with obesity and fed a high-fat diet. Remarkably, ATO-NLC prepared with olive oil, in addition to shielding its surface, would provide a stable formulation that holds up the synergistic action between olive oil and ATO. Full article