Search Results (13,780)

Plastics pyrolysis is increasingly pursued as a pathway for producing circular hydrocarbon feedstocks for petrochemical integration. However, non-integrated reactor configurations often exhibit limited heat-transfer control, significant char-handling requirements, and variable product distributions. This work presents a system-level interpretation of the MLM-R™ process, an integrated pyrolysis–combustion loop in which a circulating solid heat carrier enables continuous thermal supply through internal oxidation of carbonaceous residues. Material Flow Analysis (MFA) was applied to reconcile mass, elemental carbon, and chemical energy distributions across the defined process boundary. For the representative case study (1000 kg polyolefin basis), ~81% of feed carbon and ~83% of feed chemical energy (HHV basis) were recovered in the condensed liquid product, while ~7% of feed carbon was internally combusted to sustain autothermal operation. Simulated distillation analysis indicates that removal—aimed at further reprocessing—of a ~15 wt% C34+ heavy fraction from the pyrolysis vapor stream enables compliance with refinery-relevant boiling range targets (≥95% below 480 °C). The MFA results, supported by the physicochemical interpretation, suggest that integrated control of solids circulation and heat transfer contributes to product selectivity and process scalability in circular feedstock production. Full article

The rapid expansion of solar photovoltaic (PV) deployment has led to increasing concerns regarding end-of-life module management and the sustainability of material supply chains, where waste volumes are projected to reach 3.3–5.6 million tons by 2045. This study evaluates the environmental and economic impact of advanced photovoltaic recycling in Germany, focusing on high-value material recovery from crystalline silicon modules. A Full Recovery of End-of-Life Photovoltaics (FRELP) pathway is developed, integrating light-pulse delamination and molten salt etching, and a comparative life cycle assessment and economic assessment framework is applied. The results indicate that advanced recycling achieves high recovery rates for silicon, silver, aluminum, copper and low-iron glass, yielding around €1174.88 per ton of panels recycled. Economic analysis shows that manufacturing PV modules from recycled materials reduces costs by approximately 60–77% compared to virgin material production, mainly due to avoided energy-intensive upstream processes. From an environmental perspective, the recycling-based pathway yields net benefits across impact categories, as avoided impacts from primary material extraction outweigh additional burdens associated with recycling. Overall, PV recycling in Europe is shown to be environmentally and economically favorable; however, technological maturity and policy constraints remain key barriers to large-scale implementation and a holistic overall recycling process, indicating the need for targeted policy support. Full article

Phytoremediation is a sustainable approach for the remediation of heavy metal–contaminated soils; however, the management of contaminated biomass generated during this process remains an insufficiently addressed challenge. Such biomass constitutes a secondary waste stream that may release mobile pollutants and pose environmental risks. In this study, an integrated ecotoxicological assessment framework was applied to evaluate phytoremediation-derived biomass and its transformation products obtained via pyrolysis. Two types of woody biomass with different heavy metal contents and their corresponding biochars produced at 700 °C were investigated. A multitrophic battery of bioassays combining direct exposure assays using terrestrial organisms (higher plants, Eisenia fetida, and soil microbial activity) with leachate-based assays using aquatic organisms (Lemna minor, Daphnia magna, and Aliivibrio fischeri) was applied. Untreated biomass exhibited high to extreme toxicity in aquatic systems (toxic units, TU >100) and significant phytotoxic effects. Pyrolysis substantially reduced contaminant mobility and ecotoxicity of leachates, resulting in lower toxicity (TU typically <15) and no significant effects on plant growth, earthworm survival, or soil microbial functional diversity. Residual toxicity was linked to elevated pH and trace amounts of thermally generated organic substances. These results demonstrate that pyrolysis effectively reduces the environmental risk of contaminated biomass and supports the use of multitrophic ecotoxicological testing for safe waste valorization within circular economy strategies. Full article

The study aimed to analyze how peasant economies in the municipality of Caicedonia recognize, classify, and manage functional biodiversity associated with coffee, plantain, and orange production systems to propose a contextualized framework for species accounting and ecological cost assessment within the coffee ecosystem. A qualitative interpretive approach with exploratory quantitative support was adopted through an exploratory descriptive design and participatory action research methodology. The study integrated 21 semi structured interviews conducted with producers managing approximately 61 associated crop units distributed across diversified farming systems. Data collection included field visits, direct observation, participatory species identification exercises, and thematic interviews focused on ecological functions, agricultural practices, biodiversity management, and perceived environmental impacts. The methodological framework additionally incorporated thematic coding, functional species classification, ecological cost identification, process and strategy mapping, descriptive frequency analysis, and multiple correspondence analysis to explore relationships among crop systems, species, ecological functions, management practices, and environmental pressures. The findings indicate that producers develop consistent empirical classifications regarding pests, pollinators, biological control organisms, and ecological indicators while recognizing cumulative ecological impacts associated with intensive agricultural practices. Quantitative exploration analysis revealed differentiated ecological configurations according to crop system and biodiversity management dynamics, supporting contextualized biodiversity accounting for sustainable agronomic decision making. Full article

Background/Objectives: The precise characterization of the key microstructural and physicochemical attributes in sustained-release microspheres remains a technical bottleneck, hindering the understanding of drug release mechanisms, and limiting insights into the “process–structure–performance” relationship. To address this, we developed novel methods to conduct in-depth research on the microscopic properties of microspheres. Methods: Scanning electron microscopy (SEM) combined with a deep learning-based image segmentation (DLIS) algorithm was established for quantitative analysis of the pore structure. Laser confocal Raman spectroscopy (LCRS) was employed for in situ, non-destructive, three-dimensional (3D) visualization and quantitative mapping of the active pharmaceutical ingredient (API) distribution within microspheres. Results: This study successfully developed and applied SEM-DLIS and LCRS as reliable tools for microstructural and physicochemical characterization. SEM-DLIS analysis revealed significant differences in surface and internal pore structure among microspheres from different manufacturers and between particles of different sizes from the same batch. LCRS imaging further identified distinct API distribution patterns: uniform dispersion, outer-layer enrichment, and heterogeneous distribution. The combined data elucidate that the initial burst release is governed by the synergistic effect of surface porosity and API surface enrichment, whereas the sustained release kinetics are jointly regulated by the internal pore structure, particle size, and API spatial distribution. Conclusions: The findings establish that microstructure dictates release behavior and that all observed structural variations are linked to critical process parameters (CPPs), validating the “process determines structure” hypothesis. The established methodology provides a critical technical framework for the reverse engineering and quality equivalence assessment of generic microspheres, as well as for the quality-by-design-based optimization of innovative drug products, thereby advancing both pharmaceutical development and regulatory science. Full article

Background: Soil mulching is a widely adopted agricultural practice known to regulate soil microclimate and enhance crop productivity; yet the biochemical mechanisms by which intact plastic and biodegradable mulch films influence soil nitrogen (N) cycling at the metabolic pathway level remain largely unexplored. Understanding these nitrogen transformation pathways is critical for assessing the long-term impacts of mulching materials on soil microbial communities, soil health, and sustainable agricultural management. This study focuses on the biochemical effects of intact mulch film application on soil N metabolism. Methods: N cycle-related soil metabolites were profiled using GC‒MS/MS and MALDI TOF/TOF MS and then integrated with multivariate statistical modelling and pathway-level metabolic network perturbation analysis to compare conventional plastic and biodegradable plastic mulch film application against unmulched controls. Results: A panel of 62 KEGG-annotated N-cycle metabolites was profiled, and material-dependent metabolome separation was confirmed by OPLS-DA (R²Y 0.893–0.956; Q² 0.546–0.786). Both mulching materials significantly perturbed soil N-metabolite pools but differed in terms of pathway identity, magnitude, and directionality. Conventional plastic mulching caused the greatest disruption—near-complete suppression of N-storage and stress-adaptation pools (NES of −1.16; impact score of 10.01) and severe impairment of aspartate-centred metabolism—with L-aspartate identified as a critical stoichiometric hub. Biodegradable mulching material imposed a distinct profile dominated by inhibition of branched-chain amino acid catabolism and lysine degradation, with L-pipecolate as a treatment-specific critical impact node. Conclusions: These findings support that mulching material choice is a primary determinant of soil N-cycling biochemistry. The observed metabolite-level perturbations are suggestive of potential consequences for nitrogen retention. Though this inference is based on metabolite pool size differences and network topology metrics rather than directly measured process rates, it should therefore be interpreted with appropriate caution. Full article

Cold-chain supply systems depend on a sequence of linked production and logistics decisions. In prepared-food cold chains, quality may deteriorate not because one visible failure occurs, but because testing, traceability records, temperature monitoring, and abnormal-condition reporting are gradually weakened under cost pressure. Once such hidden effort reduction accumulates, external disturbances may push the system from strict assurance to weakened governance. To explain this nonlinear process, an asymmetric evolutionary game is built between prepared-food producers and cold-chain logistics providers, each choosing between strict and weakened quality assurance. White Gaussian noise is introduced to represent random operating shocks, and the two-population strategy system is projected onto a system-level quality-governance coordinate, q. This projection is used as a transparent baseline coordinate rather than as an assumption of linear system evolution. The reduced system is then transformed into a stochastic cusp catastrophe model, with a resilience indicator used to measure the distance from critical transition conditions. Numerical simulations show that quality assurance costs and short-term cost-saving benefits move the system toward a weakened-governance basin, whereas external incentives, coordination degree, and credible accountability mechanisms support recovery toward strict collaboration. The framework offers a scenario-based resilience diagnosis approach for identifying threshold effects in cold-chain quality governance. Digital traceability, temperature-data sharing, incentive alignment, and accountability rules are further interpreted as operational innovations that improve resilience and reduce avoidable quality losses in sustainable cold-chain operations. Full article

Polyhydroxyalkanoates (PHAs) are bio-based, biodegradable polyesters increasingly explored as sustainable biomaterials for regenerative medicine. This review summarizes recent advances in PHA-based bone substitute materials, highlighting their properties, fabrication methods, and biological performance. PHAs combine biocompatibility, tunable mechanical behavior, and degradation into non-toxic metabolites, while copolymerization and monomer selection modulate the stiffness, crystallinity, and resorption rate. Processing techniques such as solvent casting, electrospinning, and additive manufacturing allow the production of porous architectures that mimic bone extracellular matrix. Electrospinning is particularly suitable for nanoscale fibrous matrices, whereas 3D printing enables patient-specific scaffolds with controlled geometry and interconnected porosity. Scaffold performance can be further improved through the incorporation of osteoconductive fillers, including hydroxyapatite, β-tricalcium phosphate, bioactive glasses, graphene oxide, and carbon nanotubes, as well as through drug-delivery and pro-angiogenic functionalization. In vitro and in vivo studies consistently report favorable cytocompatibility, enhanced osteogenic differentiation, vascularization, and effective repair of bone defects in animal models. However, clinical translation remains limited by production costs, variability in polymer quality, thermal processing constraints, and regulatory challenges. Future progress will rely on more efficient biosynthesis, medical-grade purification, multifunctional scaffold design, and stronger collaboration between academia, industry, and clinicians to unlock the full potential of PHAs in regenerative bone therapies. Full article

The growing environmental crisis, particularly water pollution from detergents, necessitates a shift from reactive compliance to proactive eco-innovation, as current methods often fail to systematically resolve trade-offs between performance, safety, and ecology. This study develops and illustrates the application of the Evolutionary-Driven Design Framework (EDDF), an integrated methodology that combines PESTEL analysis, historical evolutionary pattern analysis, Quality Function Deployment (QFD) with a novel contradiction index, Theory of Inventive Problem Solving (TRIZ), and environmental assessment. The framework was applied to redesign a conventional laundry detergent with the objectives of zero phosphates, superior biodegradability (>85%), maintained efficacy, and controlled cost. The quantitative contradiction index matrix prioritized critical unsustainable parameters (e.g., EDTA, Cocamide DEA) for substitution over mere optimization. Through an iterative feedback loop, the process evolved from a biobased concentrate to an “enzymatic power tablet” (Concept B). This waterless, solid formulation uses sodium citrate as a biodegradable builder and an encapsulated multi-enzyme system, achieving an estimated >90% biodegradability and zero phosphates while meeting technical and economic targets. The EDDF provides a structured, anticipatory roadmap that transforms regulatory and market pressures into drivers of innovation, offering companies a promising method for designing sustainable products by proactively resolving contradictions and avoiding historical mistakes. Full article

Limited access to clean water and reliable electricity infrastructure remains a major challenge in many remote regions of Indonesia, particularly for building-scale domestic use. Conventional water treatment systems are often constrained by high operational costs and dependence on grid power, highlighting the need for sustainable and autonomous infrastructure solutions. This study presents the design, development, and performance evaluation of an integrated solar-powered clean water treatment system for smart building applications in remote areas using a Research and Development (R&D) approach. The proposed system combines off-grid polycrystalline photovoltaic panels with a multi-stage water treatment process consisting of a floss (mud) filter, activated carbon filter, water hyacinth cellulose bio-filter, ultraviolet (UV) sterilization unit, storage tank, and an IoT-based real-time water quality monitoring system. System performance was evaluated through microbiological, physical, and chemical water quality testing, with monitoring conducted via Wi-Fi-enabled sensors connected to the Blynk platform. The results demonstrate substantial improvements in treated water quality. Escherichia coli and total coliform bacteria were eliminated (100% reduction). Total dissolved solids (TDSs) decreased from 450 mg/L to 218 mg/L (51.6%), and dissolved manganese was reduced from 30 mg/L to 0.01 mg/L (99.97%), while nitrate levels decreased by 50%. Water pH and temperature remained stable and within regulatory limits. All treated water parameters complied with national clean water standards for hygiene and sanitation. The system operated independently using solar energy and achieved a clean water production capacity of 1000–1500 L/day. These findings indicate that the proposed system is a feasible, cost-effective, and sustainable civil engineering solution for clean water infrastructure in remote building environments. Full article

Allicin, the most critical bioactive compound of garlic (Allium sativum L.), is of significant industrial importance when extracted at high purity while preserving its structural integrity. In this study, the combined use of supercritical-CO₂ (SC-CO₂) extraction and molecular distillation (MD) techniques was investigated to obtain garlic extracts with high allicin content from Gaziantep (Araban) garlic. The SC-CO₂ extraction process was optimized using Response Surface Methodology (RSM) within a range of 150–300 bar pressure, 50–80% co-solvent concentration and 0.5–3.0 mL/min solvent flow rate. The obtained extracts were characterized by LC-ESI-DAD-MS/MS, and their biological activities were evaluated using a comprehensive in vitro digestion model. Allicin in vitro digestion was performed using models simulating gastrointestinal conditions of young adults (<65 years) and older adults (>65 years), and its bioactive properties were comparatively evaluated. In the antimicrobial analysis, for SC-CO₂, a strong activity was demonstrated against Staphylococcus aureus and Escherichia coli in the oral phase of the in vitro digestion model, with inhibition zones of 36.33 mm and 26.50 mm in young samples and 34.67 mm and 25.83 mm in older samples, respectively. Owing to the immediate nucleophilic attack triggered by the subsequent alkaline pH shift and pancreatic enzymatic stress, free allicin underwent total structural degradation, falling below detectable limits within the intestinal chyme. In terms of purification performance, allicin content increased from 45.77% after SC-CO₂ extraction to 67.10% after molecular distillation. Crucially, due to the immediate nucleophilic attack driven by the subsequent alkaline pH shift and pancreatic enzymatic stress, free allicin underwent complete structural degradation and was rendered strictly undetectable within the intestinal chyme. This approach provides a sustainable and environmentally friendly purification strategy that effectively limits the thermal degradation of allicin. The results present a practical framework for the scalable production of allicin-rich nutraceutical intermediates and functional food ingredients. Full article

Apple pomace is a widely available food processing by-product that has attracted increasing attention in circular and resource-efficient food systems for its potential in value-added food applications. The use of apple pomace in ready-to-eat (RTE) plant-based meat analogs represents a promising pathway. Unlike plant-based meats intended for cooking, RTE systems impose stricter constraints on structural stability, water retention, flavor integrity, and safety under cold chain conditions. Within this framework, apple pomace represents a compositionally complex material with both opportunities and constraints. This review examines how apple pomace and its derived ingredients can be utilized in RTE plant-based meat analogs, with particular attention to the distinct structural and functional requirements of minced-type and whole-cut products. Current evidence indicates that direct incorporation is more feasible for minced systems, where apple pomace fiber and pectin can support water retention, binding, and refrigerated slice stability when particle size, hydration, and sensory limits are controlled. By contrast, whole-cut applications are more likely to require fractionation, selective extraction, or additional structuring because particulate heterogeneity may disrupt continuous phase integrity and anisotropic structure formation. The review further identifies the main barriers to industrial translation, including water management under refrigerated conditions, flavor and color deviations, challenges in raw material standardization, and techno-economic constraints related to dewatering, processing intensity, and quality control. Overall, this review indicates that apple pomace can function as a technically relevant ingredient in RTE plant-based meat analogs. Its successful implementation depends on converting compositional complexity into predictable functionality through raw material standardization, controlled fraction use, food safety verification, and economically viable processing. In this way, sustainability-driven valorization can be better aligned with the practical requirements of industrial food production. Full article

Calabash (Lagenaria siceraria (Molina) Standl.) has long been an essential species for communities in Africa. Over the past decades, its production has gradually declined. Developing knowledge of existing ethnovarieties and the causes of their decline, as well of the socio-cultural services associated with the ethnovarieties and the chosen local management strategies, could contribute to their better valorization and conservation. This study aims to (i) map existing ethnovarieties, (ii) determine the endogenous management strategies, (iii) document the socio-cultural services associated with the ethnovarieties, and (iv) determine the causes of the decline. First, a non-probabilistic snowball sampling technique was used to identify the producers to be involved in the study. Then, semi-structured interviews involving 80 producers from 8 provinces across Burkina Faso were conducted using a questionnaire. Data were processed and analyzed using Microsoft Excel and R software version 4.5.0. The study revealed two types of calabashes: edible and non-edible ethnovarieties. For each type, several ethnovarieties were recorded according to socio-cultural and environmental factors. Most of the respondents were more familiar with non-edible ethnovarieties compared to the edible ones. Five socio-cultural services, including food and cultural uses, were identified. The decline of the species was associated with the relatively long production cycle of the plant, the fragility of the pericarp, the competition with alternative products, and socio-cultural restrictions limiting cultivation and knowledge transmission. Nevertheless, the persistence of certain ancestral practices still contributes to maintaining the species in local production systems. The results could help to develop contextualized strategies for the valorization, sustainable management, and in situ and ex situ conservation of calabash genetic resources in Burkina Faso and beyond. Full article

Lignin is an abundant aromatic biopolymer generated as a major by-product in lignocellulosic biorefineries, and its efficient valorization is essential for improving process sustainability and economic viability. Among current upgrading strategies, the conversion of lignin into lignin-derived biochar (LDB) has emerged as a promising route because of its high carbon yield, scalable production, and tunable physicochemical properties. This review examines the relationships between lignin structure, thermochemical conversion pathways, and the resulting properties of LDB materials within biorefinery systems. The influence of different technical lignins and conversion routes, including pyrolysis and hydrothermal carbonization, is critically discussed together with post-functionalization strategies. Particular attention is devoted to emerging applications in contaminant adsorption and controlled release systems for agrochemicals. The adsorption mechanisms governing pharmaceuticals, pesticides, microplastics, and PFAS removal are analyzed, while the dual role of LDB as both adsorbent and delivery platform is highlighted. Current limitations include lignin heterogeneity, lack of standardized evaluation protocols, and insufficient validation under realistic environmental conditions. Overall, LDB represents a versatile and scalable platform for lignin valorization and sustainable material design within circular bioeconomy frameworks. Full article

Maize is one of the most important agricultural crops worldwide, due to its high production potential and the multiple uses of its products. In the context of the need to maintain high yields and preserve soil fertility, the use of green manures together with mineral fertilizers can represent a sustainable solution. For this purpose, during the period 2024–2025, at the Turda Agricultural Research and Development Station (Cluj, Romania), a field experiment was carried out to evaluate the effect of two cover crops used as green manures, white lupin (Lupinus albus) and phacelia (Phacelia sp.), on the Turda 344 maize hybrid. Within each agrofund (classical, after lupin, and after phacelia), five fertilization variants were tested, consisting of basic fertilization and the supplementary application of mineral fertilizers and biostimulants. The results highlighted the major influence of climatic conditions on yield and grain quality, with the experimental year having a significant effect on the main parameters analyzed. In 2024, under basic fertilization, lupin and phacelia increased grain yield by 8.0% and 1.4%, respectively, compared with the classic agrofund, while in 2025, phacelia maintained a yield advantage of 1.4%. The highest yields were obtained in 2025, when climatic conditions were more favorable, and additional fertilization with ammonium nitrate determined the highest values, reaching 9748 kg/ha in the phacelia agrofund (+6.3% compared with the basic fertilization), 9544 kg/ha in the lupine agrofund (+7.2%), and 9612 kg/ha in the classical agrofund (+6.3%). Additional nitrogen application also led to the highest values of thousand kernel weight, highlighting the essential role of nitrogen in the grain filling process. Grain quality analysis showed that variations in starch and protein content had an inverse evolution between the two experimental years, suggesting the influence of climatic conditions and nitrogen availability on grain composition. Full article