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Search Results (18)

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Keywords = second-stage cesarean delivery

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11 pages, 350 KB  
Article
Effect of Previous Cesarean Section on Labor Progression: Comparison Between First VBAC and Primiparous Vaginal Deliveries
by Maayan Maor, Emmanuel Attali, Eran Ashwal, Omri Dominsky, Yariv Yogev and Yoav Baruch
J. Clin. Med. 2025, 14(24), 8903; https://doi.org/10.3390/jcm14248903 - 16 Dec 2025
Viewed by 450
Abstract
Background: The increasing number of cesarean deliveries worldwide has led to a growing population of women eligible for vaginal birth after cesarean (VBAC). limited evidence exists regarding the natural progression of labor among secundiparous women experiencing their first vaginal delivery. Evidence regarding labor [...] Read more.
Background: The increasing number of cesarean deliveries worldwide has led to a growing population of women eligible for vaginal birth after cesarean (VBAC). limited evidence exists regarding the natural progression of labor among secundiparous women experiencing their first vaginal delivery. Evidence regarding labor progression among women attempting VBAC remains inconclusive and with conflicting results. Clarifying these differences is essential for optimizing intrapartum management. Our objective was to compare the progression rate of the active phase of labor between secundiparous womne at their first VBAC and primiparous women who delivered vaginally. Methods: A retrospective cohort study was conducted at a tertiary university-affiliated medical center (January 2011–January 2021). Included were term singleton pregnancies in spontaneous labor resulting in vaginal delivery. Exclusion criteria included induction, augmentation, and operative vaginal delivery. Results: Among 13,983 primiparous and 736 VBAC patients, the VBAC group was older, used epidural more frequently, and had higher neonatal birth weight. The cervical dilatation rate during the active phase was faster in VBAC patients (3.26 vs. 2.85 cm/h, p = 0.011), with a shorter second stage (77.8 vs. 86.6 min, p < 0.001). The rate of prolonged second stage was higher in the primiparous group (9.5% vs. 7.1%, p = 0.029). In a multivariable analysis examining the association between VBAC and prolonged second stage, VBAC was found to be inversely associated with prolonged second stage (OR 0.541, 95% CI 0.388–0.753, p = 0.001). Conclusions: When compared to primiparous women, women at their first VBAC had significantly shorter active phase and increased progression rate as well as a shorter second stage of labor. Full article
(This article belongs to the Section Obstetrics & Gynecology)
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22 pages, 10233 KB  
Article
Artificial Intelligence Dystocia Algorithm (AIDA) as a Decision Support System in Transverse Fetal Head Position
by Antonio Malvasi, Lorenzo E. Malgieri, Tommaso Difonzo, Reuven Achiron, Andrea Tinelli, Giorgio Maria Baldini, Lorenzo Vasciaveo, Renata Beck, Ilenia Mappa and Giuseppe Rizzo
J. Imaging 2025, 11(7), 223; https://doi.org/10.3390/jimaging11070223 - 5 Jul 2025
Cited by 3 | Viewed by 1565
Abstract
Transverse fetal head position during labor is associated with increased rates of operative deliveries and cesarean sections. Traditional assessment methods rely on digital examination, which can be inaccurate in cases of prolonged labor. Intrapartum ultrasound offers improved diagnostic capabilities, but standardized interpretation frameworks [...] Read more.
Transverse fetal head position during labor is associated with increased rates of operative deliveries and cesarean sections. Traditional assessment methods rely on digital examination, which can be inaccurate in cases of prolonged labor. Intrapartum ultrasound offers improved diagnostic capabilities, but standardized interpretation frameworks are needed. This study aimed to evaluate the significance of appropriate assessment and management of transverse fetal head position during labor, with particular emphasis on the correlation between geometric parameters and delivery outcomes. Additionally, the investigation analyzed the potential role of Artificial Intelligence Dystocia Algorithm (AIDA) as an innovative decision support system in standardizing diagnostic approaches and optimizing clinical decision-making in cases of fetal malposition. This investigation was conducted as a focused secondary analysis of data originally collected for the development and validation of the Artificial Intelligence Dystocia Algorithm (AIDA). The study examined 66 cases of transverse fetal head position from a cohort of 135 nulliparous women with prolonged second-stage labor across three Italian hospitals. Cases were stratified by Midline Angle (MLA) measurements into classic transverse (≥75°), near-transverse (70–74°), and transitional (60–69°) positions. Four geometric parameters (Angle of Progression, Head–Symphysis Distance, Midline Angle, and Asynclitism Degree) were evaluated using the AIDA classification system. The predictive capabilities of three machine learning algorithms (Support Vector Machine, Random Forest, and Multilayer Perceptron) were assessed, and delivery outcomes were analyzed. The AIDA system successfully categorized labor dystocia into five distinct classes, with strong predictive value for delivery outcomes. A clear gradient of cesarean delivery risk was observed across the spectrum of transverse positions (100%, 93.1%, and 85.7% for near-transverse, classic transverse, and transitional positions, respectively). All cases classified as AIDA Class 4 required cesarean delivery regardless of the specific MLA value. Machine learning algorithms demonstrated high predictive accuracy, with Random Forest achieving 95.5% overall accuracy across the study cohort. The presence of concurrent asynclitism with transverse position was associated with particularly high rates of cesarean delivery. Among the seven cases that achieved vaginal delivery despite transverse positioning, none belonged to the classic transverse positions group, and five (71.4%) exhibited at least one parameter classified as favorable. The integration of artificial intelligence through AIDA as a decision support system, combined with intrapartum ultrasound, offered a promising approach for objective assessment and management of transverse fetal head position. The AIDA classification system’s integration of multiple geometric parameters, with particular emphasis on precise Midline Angle (MLA) measurement in degrees, provided superior predictive capability for delivery outcomes compared to qualitative position assessment alone. This multidimensional approach enabled more personalized and evidence-based management of malpositions during labor, potentially reducing unnecessary interventions while identifying cases where expectant management might be futile. Further prospective studies are needed to validate the predictive capability of this decision support system and its impact on clinical decision-making in real-time labor management. Full article
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19 pages, 1211 KB  
Article
Associations Between Physical Activity in Pregnancy and Maternal, Perinatal, and Neonatal Parameters: A Single-Center Prospective Cohort Study
by Paulina Majewska and Anna Szablewska
J. Clin. Med. 2025, 14(7), 2325; https://doi.org/10.3390/jcm14072325 - 28 Mar 2025
Cited by 2 | Viewed by 5528
Abstract
Background: Physical activity during pregnancy plays an important role in influencing the course of pregnancy, the health of the mother, and neonatal outcomes. Regular exercise can positively affect maternal well-being, reduce the risk of pregnancy-related complications, and support optimal fetal development. Additionally, [...] Read more.
Background: Physical activity during pregnancy plays an important role in influencing the course of pregnancy, the health of the mother, and neonatal outcomes. Regular exercise can positively affect maternal well-being, reduce the risk of pregnancy-related complications, and support optimal fetal development. Additionally, physical activity may contribute to a reduced need for C-sections and better postpartum recovery. Despite these benefits, global trends indicate a decline in physical activity levels, exacerbated by lifestyle changes such as remote work. This highlights the importance of promoting healthy habits among women of reproductive age to improve perinatal outcomes and the long-term health of both mothers and their children. Objective: The aim of this study was to investigate the effects of physical activity during pregnancy on the health of mothers and babies after birth. Methods: A prospective cohort study was conducted in a tertiary care hospital in northern Poland from October 2024 to December 2024. Participants were 205 pregnant women with no medical contraindications to physical activity. The group was selected on the basis of a questionnaire with original questions and the Get Active Questionnaire for Pregnancy (GAQ-P). The effects of physical activity during pregnancy on maternal and infant health after delivery were assessed using questionnaire data and medical records. Frequency analysis supported by chi-squared coefficient; Cramer’s V coefficient and Spearman’s rank correlation were used to answer the research questions. Results: The study showed that the frequency of physical activity had an effect on the incidence of perineal trauma, the baby’s birth weight, and the baby’s degree of saturation after birth. The intensity of physical activity during pregnancy may influence the duration of the first stage of labor, while the duration of physical activity may influence the duration of the second stage of labor and reduce the number of operative deliveries. Conclusions: Although physical activity has a huge impact on the course of pregnancy and the health of both mother and child after birth, more research is needed to draw clear conclusions. In our study, a beneficial effect of physical activity on the reduction in cesarean sections can be observed. However, the effects on perineal injuries, length of labor, and birth weight require further research, as our findings indicate that higher exercise frequency was associated with both positive outcomes, such as fewer cesarean sections, and potential risks, including an increase in macrosomia and perineal tears. A broader analysis of co-factors influencing these results is needed to fully understand these relationships. Full article
(This article belongs to the Section Obstetrics & Gynecology)
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10 pages, 1445 KB  
Article
Adherence to Labor Arrest and Failed Induction of Labor Guidelines: The Impact of a Quality-Improvement Educational Intervention
by Jennifer J. M. Cate, Christopher K. Arkfeld, Meagan Campol, Katherine H. Campbell, Christian M. Pettker and Jessica L. Illuzzi
J. Clin. Med. 2024, 13(16), 4720; https://doi.org/10.3390/jcm13164720 - 12 Aug 2024
Cited by 1 | Viewed by 2331
Abstract
Background/Objective: To evaluate adherence to labor arrest and failed induction of labor (IOL) criteria in nulliparous, term, singleton, and vertex (NTSV) cesarean deliveries at an academic medical center and to measure the impact of a quality-improvement educational initiative that focused on obstetric provider [...] Read more.
Background/Objective: To evaluate adherence to labor arrest and failed induction of labor (IOL) criteria in nulliparous, term, singleton, and vertex (NTSV) cesarean deliveries at an academic medical center and to measure the impact of a quality-improvement educational initiative that focused on obstetric provider education of modern labor arrest and failed IOL criteria. Methods: This is a retrospective cohort study using electronic health record (EHR) data with a pre- (1 September 2018–30 September 2019) and post-intervention (1 October 2019–31 March 2020) study design of all NTSV cesarean deliveries for labor arrest or failed IOL performed at an academic medical center in the northeastern United States. The quality-improvement educational intervention consisted of the distribution of educational pocket cards outlining modern labor arrest and failed IOL criteria to obstetric providers. Outcomes included adherence to labor arrest and failed IOL criteria pre- and post-intervention with secondary outcomes evaluating adherence by provider type (Maternal–Fetal Medicine (MFM) or generalist obstetrician). Descriptive and bivariate statistics were used in the analysis. Results: Pre-intervention, 272 NTSV cesarean deliveries were performed for labor arrest or failed IOL versus 92 post-intervention. Adherence improved post-intervention amongst failed IOL (OR 6.5, CI 1.8–23.8), first-stage arrest (OR 4.5, CI 2.2–10.8) and second-stage arrest (OR 3.7, CI 1.5–9.4). When comparing provider type, MFM physicians were more likely to be adherent to labor arrest and failed IOL criteria compared to generalist obstetricians pre-intervention (OR 3.1, CI 1.7–5.5); however, post-intervention, there was no longer a difference in adherence (OR 3.3, CI 0.9–12.3). Conclusions: Adherence to labor arrest criteria was suboptimal in the pre-intervention period; however, a targeted quality-improvement educational intervention improved adherence rates to labor arrest and failed IOL criteria among obstetric providers. Full article
(This article belongs to the Special Issue Progress in Patient Safety and Quality in Maternal–Fetal Medicine)
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22 pages, 1969 KB  
Article
AIDA (Artificial Intelligence Dystocia Algorithm) in Prolonged Dystocic Labor: Focus on Asynclitism Degree
by Antonio Malvasi, Lorenzo E. Malgieri, Ettore Cicinelli, Antonella Vimercati, Reuven Achiron, Radmila Sparić, Antonio D’Amato, Giorgio Maria Baldini, Miriam Dellino, Giuseppe Trojano, Renata Beck, Tommaso Difonzo and Andrea Tinelli
J. Imaging 2024, 10(8), 194; https://doi.org/10.3390/jimaging10080194 - 9 Aug 2024
Cited by 7 | Viewed by 3538
Abstract
Asynclitism, a misalignment of the fetal head with respect to the plane of passage through the birth canal, represents a significant obstetric challenge. High degrees of asynclitism are associated with labor dystocia, difficult operative delivery, and cesarean delivery. Despite its clinical relevance, the [...] Read more.
Asynclitism, a misalignment of the fetal head with respect to the plane of passage through the birth canal, represents a significant obstetric challenge. High degrees of asynclitism are associated with labor dystocia, difficult operative delivery, and cesarean delivery. Despite its clinical relevance, the diagnosis of asynclitism and its influence on the outcome of labor remain matters of debate. This study analyzes the role of the degree of asynclitism (AD) in assessing labor progress and predicting labor outcome, focusing on its ability to predict intrapartum cesarean delivery (ICD) versus non-cesarean delivery. The study also aims to assess the performance of the AIDA (Artificial Intelligence Dystocia Algorithm) algorithm in integrating AD with other ultrasound parameters for predicting labor outcome. This retrospective study involved 135 full-term nulliparous patients with singleton fetuses in cephalic presentation undergoing neuraxial analgesia. Data were collected at three Italian hospitals between January 2014 and December 2020. In addition to routine digital vaginal examination, all patients underwent intrapartum ultrasound (IU) during protracted second stage of labor (greater than three hours). Four geometric parameters were measured using standard 3.5 MHz transabdominal ultrasound probes: head-to-symphysis distance (HSD), degree of asynclitism (AD), angle of progression (AoP), and midline angle (MLA). The AIDA algorithm, a machine learning-based decision support system, was used to classify patients into five classes (from 0 to 4) based on the values of the four geometric parameters and to predict labor outcome (ICD or non-ICD). Six machine learning algorithms were used: MLP (multi-layer perceptron), RF (random forest), SVM (support vector machine), XGBoost, LR (logistic regression), and DT (decision tree). Pearson’s correlation was used to investigate the relationship between AD and the other parameters. A degree of asynclitism greater than 70 mm was found to be significantly associated with an increased rate of cesarean deliveries. Pearson’s correlation analysis showed a weak to very weak correlation between AD and AoP (PC = 0.36, p < 0.001), AD and HSD (PC = 0.18, p < 0.05), and AD and MLA (PC = 0.14). The AIDA algorithm demonstrated high accuracy in predicting labor outcome, particularly for AIDA classes 0 and 4, with 100% agreement with physician-practiced labor outcome in two cases (RF and SVM algorithms) and slightly lower agreement with MLP. For AIDA class 3, the RF algorithm performed best, with an accuracy of 92%. AD, in combination with HSD, MLA, and AoP, plays a significant role in predicting labor dystocia and labor outcome. The AIDA algorithm, based on these four geometric parameters, has proven to be a promising decision support tool for predicting labor outcome and may help reduce the need for unnecessary cesarean deliveries, while improving maternal-fetal outcomes. Future studies with larger cohorts are needed to further validate these findings and refine the cut-off thresholds for AD and other parameters in the AIDA algorithm. Full article
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9 pages, 724 KB  
Case Report
Hamman’s Syndrome after Vaginal Delivery: A Case of Postpartum Spontaneous Pneumomediastinum with Subcutaneous Emphysema and Review of the Literature
by Kristina Olafsen-Bårnes, Marte Mari Kaland, Karol Kajo, Lars Jakob Rydsaa, Jozef Visnovsky and Pavol Zubor
Healthcare 2024, 12(13), 1332; https://doi.org/10.3390/healthcare12131332 - 3 Jul 2024
Cited by 3 | Viewed by 3049
Abstract
Hamman’s syndrome is a rare condition that mostly affects young males, often with a predisposition to asthma. It includes the presence of free air in the mediastinum and subcutaneous emphysema with no other underlying cause such as trauma, infection, or administration of any [...] Read more.
Hamman’s syndrome is a rare condition that mostly affects young males, often with a predisposition to asthma. It includes the presence of free air in the mediastinum and subcutaneous emphysema with no other underlying cause such as trauma, infection, or administration of any sort of mask support with hyperpressure. It occurs spontaneously and often in association with a prolonged Valsalva maneuver. This might explain why there are some cases of Hamman’s syndrome among young females giving birth. Here, we present a case report of a 24-year-old non-smoker primigravida with Hamman’s syndrome. She presented with symptoms a few hours after an uncomplicated vaginal delivery at 40 + 1 weeks of pregnancy where the active phase of labor lasted for three hours with normal progress. The second stage lasted for 30 min, with no signs of distress on CTG. The symptoms (pain in the right ear, swelling and pain in the neck, chest tightness, shortness of breath, dysphagia, odynophagia, and pain in the upper thorax on the right side) and objective findings as subcutaneous crepitations in the neck, parasternal region, right axillary fossa, clavicle and over the chest resolved spontaneously after a few days of observation and conservative management. We also give a systemic review of reported cases since 2000 to provide an overview of the pathomechanism, symptoms, diagnostics, treatment, and management of this condition. Hamman’s syndrome is a rare, usually benign, but potentially serious complication that can occur during the second stage of labor. Diagnostics include inquiring about typical symptoms, clinical examination, and chest x-ray or CT scan. Treatment is usually conservative with oxygen, bronchodilators, and pain relief. The recurrence rate is low and there is no contraindication to vaginal delivery in future pregnancies. However, it is suggested that physicians and midwives be cautious and consider a low threshold for instrumental delivery or cesarean section to avoid excessive Valsalva maneuvers. Full article
(This article belongs to the Special Issue 2nd Edition: Pregnancy and Perinatal Health)
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11 pages, 1438 KB  
Article
Ultrasonographic Evaluation of the Second Stage of Labor according to the Mode of Delivery: A Prospective Study in Greece
by Kyriaki Mitta, Ioannis Tsakiridis, Themistoklis Dagklis, Ioannis Kalogiannidis, Apostolos Mamopoulos, Georgios Michos, Andriana Virgiliou and Apostolos Athanasiadis
J. Clin. Med. 2024, 13(4), 1068; https://doi.org/10.3390/jcm13041068 - 13 Feb 2024
Cited by 3 | Viewed by 2630
Abstract
Background and Objectives: Accurate diagnosis of labor progress is crucial for making well-informed decisions regarding timely and appropriate interventions to optimize outcomes for both the mother and the fetus. The aim of this study was to assess the progress of the second stage [...] Read more.
Background and Objectives: Accurate diagnosis of labor progress is crucial for making well-informed decisions regarding timely and appropriate interventions to optimize outcomes for both the mother and the fetus. The aim of this study was to assess the progress of the second stage of labor using intrapartum ultrasound. Material and methods: This was a prospective study (December 2022–December 2023) conducted at the Third Department of Obstetrics and Gynecology, School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, Greece. Maternal–fetal and labor characteristics were recorded, and two ultrasound parameters were measured: the angle of progression (AoP) and the head–perineum distance (HPD). The correlation between the two ultrasonographic values and the maternal–fetal characteristics was investigated. Multinomial regression analysis was also conducted to investigate any potential predictors of the mode of delivery. Results: A total of 82 women at the second stage of labor were clinically and sonographically assessed. The mean duration of the second stage of labor differed between vaginal and cesarean deliveries (65.3 vs. 160 min; p-value < 0.001) and between cesarean and operative vaginal deliveries (160 vs. 88.6 min; p-value = 0.015). The occiput anterior position was associated with an increased likelihood of vaginal delivery (OR: 24.167; 95% CI: 3.8–152.5; p-value < 0.001). No significant differences were identified in the AoP among the three different modes of delivery (vaginal: 145.7° vs. operative vaginal: 139.9° vs. cesarean: 132.1°; p-value = 0.289). The mean HPD differed significantly between vaginal and cesarean deliveries (28.6 vs. 41.4 mm; p-value < 0.001) and between cesarean and operative vaginal deliveries (41.4 vs. 26.9 mm; p-value = 0.002); it was correlated significantly with maternal BMI (r = 0.268; p-value = 0.024) and the duration of the second stage of labor (r = 0.256; p-value = 0.031). Low parity (OR: 12.024; 95% CI: 6.320–22.876; p-value < 0.001) and high HPD (OR: 1.23; 95% CI: 1.05–1.43; p-value = 0.007) were found to be significant predictors of cesarean delivery. Conclusions: The use of intrapartum ultrasound as an adjunctive technique to the standard clinical evaluation may enhance the diagnostic approach to an abnormal labor progress and predict the need for operative vaginal or cesarean delivery. Full article
(This article belongs to the Special Issue Clinical Risks and Perinatal Outcomes in Pregnancy and Childbirth)
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11 pages, 675 KB  
Article
Cesarean Uterine Lacerations and Prematurity in the Following Delivery: A Retrospective Longitudinal Follow-Up Cohort Study
by Orna Reichman, Ayala Hirsch, Shira Fridman, Sorina Grisaru-Granovsky and Sarit Helman
J. Clin. Med. 2024, 13(3), 749; https://doi.org/10.3390/jcm13030749 - 28 Jan 2024
Viewed by 1801
Abstract
(1) Background: We aimed to investigate whether second-stage cesarean delivery (SSCD) had a higher occurrence of low-segment uterine incision extensions compared with cesarean delivery (CD) at other stages of labor and to study the association of these extensions with preterm birth (PTB). [...] Read more.
(1) Background: We aimed to investigate whether second-stage cesarean delivery (SSCD) had a higher occurrence of low-segment uterine incision extensions compared with cesarean delivery (CD) at other stages of labor and to study the association of these extensions with preterm birth (PTB). (2) Methods: In this retrospective longitudinal follow-up cohort study, spanning from 2006 to 2019, all selected mothers who delivered by CD at first birth (P1) and returned for second birth (P2) were grouped by cesarean stage at P1: planned CD, first-stage CD, or SSCD. Mothers with a PTB at P1, multiple-gestation pregnancies in either P1 or P2 and those with prior abortions were excluded. (3) Results: The study included 1574 selected women who underwent a planned CD at P1 (n = 483 (30.7%)), first-stage CD (n = 878 (55.8%), and SSCD (n = 213 (13.5%)). There was a higher occurrence of low-segment uterine incision extensions among SSCD patients compared to first-stage CDs and planned CDs: 50/213 (23%), 56/878 (6.4%), and 5/483 (1%), respectively (p < 0.001). A multivariate logistic regression showed that women undergoing an SSCD are at risk for low-segment uterine incision extensions compared with women undergoing a planned CD, OR 28.8 (CI 11.2; 74.4). We observed no association between the occurrence of a low-segment uterine incisional extension at P1 and PTB ≤ 37 gestational weeks in the subsequent delivery, with rates of 6.3% (7/111) for those with an extension compared to 4.5% (67/1463) for those without an extension (p = 0.41). Notably, parturients experiencing a low-segment uterine incisional extension during their first childbirth were six times more likely to have a preterm delivery before 32 weeks of gestation compared to those without extensions, with two cases (1.8%) compared to four cases (0.3%), respectively. A similar trend was observed for preterm deliveries between 32 and 34 weeks of gestation, with those having extensions showing twice the prevalence of prematurity compared to those without, with a p-value of 0.047. (4) Conclusions: This study highlights that mothers undergoing SSCD experience higher prevalence of low uterine incision extensions compared to other CDs. To further ascertain whether the presence of these extensions is associated with preterm birth (PTB) in subsequent births, particularly early PTB before 34 weeks of gestation, larger-scale future studies are warranted. Full article
(This article belongs to the Section Obstetrics & Gynecology)
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9 pages, 261 KB  
Article
Effect of Pethidine Injection on the Duration of Labor and Pregnancy Outcomes: A Retrospective Cohort Study
by Eun Byeol Cho, Hyun Joo Chae, Jung Min Ryu, Hyo Jin Lee, Seong Yeon Hong and Jin Young Bae
Medicina 2024, 60(1), 143; https://doi.org/10.3390/medicina60010143 - 12 Jan 2024
Cited by 1 | Viewed by 10320
Abstract
Background and Objectives: Long and ineffective labor causes hardships for mothers and doctors and increases the rate of cesarean sections and medical comorbidities. Several factors contribute to effective and less painful labor, including maternal age, parity, fetal characteristics, and the medications or [...] Read more.
Background and Objectives: Long and ineffective labor causes hardships for mothers and doctors and increases the rate of cesarean sections and medical comorbidities. Several factors contribute to effective and less painful labor, including maternal age, parity, fetal characteristics, and the medications or procedures that obstetricians use for labor. We aimed to study the factors that affect labor duration and identify those that make labor more effective. Materials and Methods: This retrospective study included 141 patients who underwent normal vaginal deliveries at the Daegu Catholic University Medical Center between April 2013 and April 2022. Among the 141 patients, 44 received pethidine intravenously, 88 received oxytocin intravenously, and 64 received epidural anesthesia. The duration of the active phase and second stage of labor were recorded according to the findings of a manual examination of the cervix and continuous external electronic monitoring. We analyzed maternal and neonatal medical records and performed binomial logistic regression to identify the factors associated with a shorter active phase of labor. The clinical outcomes in mothers and neonates were also evaluated. Results: Among the various clinical factors, multiparity (odds ratio of parity 0.325) and the use of pethidine (odds ratio 2.906) were significantly associated with shortening the active phase of labor to less than 60 min. The use of epidural anesthesia or oxytocin was not significantly associated with reducing the active phase of labor. When patients were divided into two groups based on whether a pethidine injection had been used during labor, the duration of the active phase was shorter in the pethidine injection group than in the control group for both nulliparas and multiparas. No significant differences in the duration of the second stage of labor were observed between the pethidine injection and control groups. There were no significant differences in pregnancy outcomes, including the need for mechanical ventilation of neonates, Apgar scores, neonatal intensive care unit admissions, number of precipitous deliveries, maternal adverse side effects of drugs, or duration of maternal hospitalization between the two groups. Conclusions: Pethidine can be safely administered to women during labor to help reduce the duration of the active phase by promoting dilatation of the cervix and preventing complications that may result from prolonged labor. Pethidine may be helpful, especially for those who cannot receive epidural anesthesia or who cannot afford it. However, large-scale randomized controlled studies are required to evaluate the efficacy and safety of this drug during labor. Furthermore, it would be helpful if various studies were conducted depending on the timing of administration and indications for delivery. Full article
9 pages, 514 KB  
Article
Risk of Preterm Birth among Secundiparas with a Previous Cesarean due to a Failed Vacuum Delivery
by Sarit Helman, Muhammad Mahajna, Zvi Ehrlich, Miri Ratner, Sorina Grisaru-Granovsky and Orna Reichman
J. Clin. Med. 2023, 12(23), 7358; https://doi.org/10.3390/jcm12237358 - 28 Nov 2023
Cited by 5 | Viewed by 1575
Abstract
Background: Studies have found an association between second-stage cesarean sections (SSCSs) and subsequent preterm birth (PTB). We aimed to evaluate if secundiparas with previous second-stage cesarean sections due to a failed vacuum delivery (SSCS-F-VD) are associated with PTB in the subsequent delivery compared [...] Read more.
Background: Studies have found an association between second-stage cesarean sections (SSCSs) and subsequent preterm birth (PTB). We aimed to evaluate if secundiparas with previous second-stage cesarean sections due to a failed vacuum delivery (SSCS-F-VD) are associated with PTB in the subsequent delivery compared with secundiparas with previous spontaneous vaginal birth (SVB) at term. A secondary aim was to compare this association with secundiparas with a previous SSCS at term. Methods: A historical, prospective, longitudinal cohort study was conducted in a large tertiary university hospital between 2006 and 2019. Matched mothers who experienced first and second births at the indexed hospital, excluding those with a previous miscarriage or multiple pregnancy in either the first or second birth were grouped based on the mode of delivery and gestational week of the first birth. Results: Parturients with term SVB and term SSCSs were less likely to experience PTB in the following delivery compared with those who underwent an SSCS-F-VD, with 496/14,551 (3.4%) versus 6/160 (3.8%) versus 5/61 (8.2%), respectively, at p < 0.001. A logistic regression model revealed that secundiparas with previous SSCS-F-VD had an association with PTB in the following delivery compared with term SVB, with an OR of 2.756 (1.097; 6.922, p = 0.031). Conclusion: Previous SSCS-F-VD is associated with PTB in the following delivery, offering valuable insights for pregnancy management and patient counseling. Full article
(This article belongs to the Section Obstetrics & Gynecology)
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12 pages, 619 KB  
Article
Delivery Progress, Labor Interventions and Perinatal Outcome in Spontaneous Vaginal Delivery of Singleton Pregnancies between Nulliparous and Primiparous Women with One Previous Elective Cesarean Section: A Retrospective Comparative Study
by Grigorios Karampas, Martin Witkowski, Dimitra Metallinou, Margareta Steinwall, Alkis Matsas, Theodoros Panoskaltsis and Panagiotis Christopoulos
Life 2023, 13(10), 2016; https://doi.org/10.3390/life13102016 - 5 Oct 2023
Cited by 2 | Viewed by 3775
Abstract
Trial of labor after cesarean (TOLAC) is an alternative to repeated cesarean for women with singleton pregnancy and one previous transverse lower segment cesarean section (LSCS), resulting in most cases being a successful vaginal birth after cesarean section (VBAC). The primary objective of [...] Read more.
Trial of labor after cesarean (TOLAC) is an alternative to repeated cesarean for women with singleton pregnancy and one previous transverse lower segment cesarean section (LSCS), resulting in most cases being a successful vaginal birth after cesarean section (VBAC). The primary objective of this study was to examine if the progress and the duration of the active first stage and the second stage of labor in nulliparous women with singleton pregnancy, spontaneous start of labor and vaginal birth differ from primiparous women succeeding VBAC after one previous elective LSCS in a country with a low cesarean section and high VBAC rate. Secondary objectives were to compare labor interventions and maternal–neonatal outcomes between the two groups. Methods: This is a retrospective comparative study. Data were collected in a four-year period at the departments of Obstetrics and Gynecology at Kristianstad and Ystad hospitals in Sweden. Out of 14,925 deliveries, 106 primipara women with one previous elective LSCS and a spontaneous labor onset in the subsequent singleton pregnancy were identified. Of these women, 94 (88.7%) delivered vaginally and were included in the study (VBAC group). The comparison group included 212 randomly selected nulliparous women that had a normal singleton pregnancy, spontaneous labor onset and delivered vaginally. Results: The rate of cervical dilation during the active first stage of labor as well as the duration of the second stage did not differ between the two groups. When adjusting for cervical dilation at admission, there was no significant difference between the two groups regarding the duration of the active phase of the first stage of labor. No significant differences were found in maternal–neonatal outcomes between the two groups except for higher birth weight in the VBAC group. The use of epidural analgesia was associated with slower dilation rhythm over the duration of the active phase and second stage of labor, need for labor augmentation, postpartum bleeding and need for transfusion at higher rates, irrespective of parity when epidural was used. Conclusions: Our study provides evidence that in women with one previous elective LSCS undergoing TOLAC in the subsequent pregnancy resulting in vaginal birth, the progress and duration of labor are not different from those in nulliparous women when labor is spontaneous and the it is a singleton pregnancy. The use of epidural was associated with prolonged labor, need for labor augmentation and higher postpartum bleeding, irrespective of parity. This information may be useful in patient counseling and labor management in TOLAC. Full article
(This article belongs to the Special Issue Diagnosis and Treatment of Obstetrics and Gynecology Diseases)
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7 pages, 227 KB  
Article
Bloody Amniotic Fluid and Neonatal Outcomes
by Hanoch Schreiber, Gal Cohen, Hila Shalev-Ram, Sivan Farladansky-Gershnabel, Omer Weitzner, Tal Biron-Shental, Michal Kovo, Shmuel Arnon and Ofer Markovitch
Children 2023, 10(7), 1208; https://doi.org/10.3390/children10071208 - 12 Jul 2023
Cited by 1 | Viewed by 5596
Abstract
Information on the effect of bloody amniotic fluid during labor at term is scarce. This study assessed risk factors and adverse outcomes in labors with bloody amniotic fluid. During the six years of this study, all nulliparas in our institution, with a trial [...] Read more.
Information on the effect of bloody amniotic fluid during labor at term is scarce. This study assessed risk factors and adverse outcomes in labors with bloody amniotic fluid. During the six years of this study, all nulliparas in our institution, with a trial of labor, were included. Multiple pregnancies and preterm deliveries were excluded. Outcomes were compared between the bloody amniotic fluid group and the clear amniotic fluid group. Overall, 11,252 women were included. Among them, 364 (3.2%) had bloody amniotic fluid and 10,888 (96.7%) had clear amniotic fluid. Women in the bloody amniotic fluid group were characterized by shorter duration of the second stage and higher rate of cesarean section due to non-reassuring fetal heart rate. In addition, there were higher rates of low cord pH (<7.1) and NICU admissions in the bloody amniotic fluid group. In multivariate logistic regression analysis, cesarean delivery, cord blood pH < 7.1, and NICU admission were independently associated with increased odds ratio for bloody amniotic fluid. Bloody amniotic fluid at term is associated with adverse outcomes and must be considered during labor. Full article
(This article belongs to the Special Issue Issues Involving Prenatal Findings and Neonatal Outcomes)
9 pages, 878 KB  
Article
Partogram of Grandmultiparous Parturients: A Multicenter Cohort Study
by Joshua Guedalia, Michal Lipschuetz, Asnat Walfisch, Sarah M. Cohen, Eyal Sheiner, Abraham O. Samson, Joshua Rosenbloom, Doron Kabiri and Hila Hochler
J. Clin. Med. 2023, 12(2), 592; https://doi.org/10.3390/jcm12020592 - 11 Jan 2023
Cited by 4 | Viewed by 2695
Abstract
Sparse and conflicting data exist regarding the normal partogram of grand-multiparous (GMP, defined as parity of 6+) parturients. Customized partograms may potentially lower cesarean delivery rates for protraction disorders in this population. In this study, we aim to construct a normal labor curve [...] Read more.
Sparse and conflicting data exist regarding the normal partogram of grand-multiparous (GMP, defined as parity of 6+) parturients. Customized partograms may potentially lower cesarean delivery rates for protraction disorders in this population. In this study, we aim to construct a normal labor curve of GMP women and compare it to the multiparous (MP, defined as parity of 2–5) partogram. We conducted a multicenter retrospective cohort analysis of deliveries between the years 2003 and 2019. Eligible parturients were the trials of labor of singletons ≥37 + 0 weeks in cephalic presentation with ≥2 documented cervical examinations during labor. Exclusion criteria were elective cesarean delivery without a trial of labor, preterm labor, major fetal anomalies, and fetal demise. GMP comprised the study group while the MP counterparts were the control group. A total of 78,292 deliveries met the inclusion criteria, comprising 10,532 GMP and 67,760 MP parturients. Our data revealed that during the first stage of labor, cervical dilation progressed at similar rates in MPs and GMPs, while head descent was a few minutes faster in GMPs compared to MPs, regardless of epidural anesthesia. The second stage of labor was faster in GMPs compared to MPs; the 95th percentile of the second stage duration of GMPs (48 min duration) was 43 min less than that of MPs (91 min duration). These findings remained similar among deliveries with and without epidural analgesia or labor induction. We conclude that GMPs’ and MPs’ cervical dilation progression in the active phase of labor was similar, and the second stage of labor was shorter in GMPs, regardless of epidural use. Thus, GMPs’ uterus function during labor corresponds, and possibly surpasses, that of MPs. These findings indicate that health providers can use the standard partogram of the active phase of labor when caring for GMP parturients. Full article
(This article belongs to the Section Obstetrics & Gynecology)
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14 pages, 296 KB  
Article
Episiotomy for Medical Indications during Vaginal Birth—Retrospective Analysis of Risk Factors Determining the Performance of This Procedure
by Grażyna Bączek, Sylwia Rychlewicz, Dorota Sys, Patryk Rzońca and Justyna Teliga-Czajkowska
J. Clin. Med. 2022, 11(15), 4334; https://doi.org/10.3390/jcm11154334 - 26 Jul 2022
Cited by 9 | Viewed by 5641
Abstract
The WHO (World Health Organization) recommends that the percentage of perineal incisions should not exceed 10%, indicating that this is a good goal to achieve, despite the fact that it is still a frequently used medical intervention in Poland. The risk factors for [...] Read more.
The WHO (World Health Organization) recommends that the percentage of perineal incisions should not exceed 10%, indicating that this is a good goal to achieve, despite the fact that it is still a frequently used medical intervention in Poland. The risk factors for perineal incision that have been analyzed so far in the literature allow, among others, to limit the frequency of performing this procedure. Are they still valid? Have there been new risk factors that we should take into account? We have conducted this study to find the risk factors for performing perineal incision that would reduce the frequency of this procedure. The aim of the study was to check whether the risk factors that were analyzed in the literature are still valid, to find new risk factors for perineal incisions and to compare them among Polish women. This was a single-center retrospective case-control study. The electronic patient records of Saint Sophia’s Hospital in Warsaw, Poland, a tertiary hospital was used to create an anonymous retrospective database of all deliveries from 2015 to 2020. The study included the analysis of two groups, the study group of patients who had had an episiotomy, and the control group-patients without an episiotomy in cases where an episiotomy was indicated. A logistic regression model was developed to assess the risk factors for perineal laceration. Independent risk factors for episiotomy in labor include oxytocin use in the second stage of labor (OR (Odds Ratio) = 6.00; 95% CI (Confidence Interval): 4.76–7.58), the supply of oxytocin in the first and the second stage of labor (OR = 3.18; 95% CI: 2.90–3.49), oxytocin use in the first stage of labor (OR = 2.72; 95% CI: 2.52–3.51), state after cesarean section (OR = 2.97; 95% CI: 2.52–3.51), epidural anesthesia use (OR = 1.77; 95% CI: 1.62–1.93), male gender (OR = 1.10; 95% CI: 1.02–1.19), and prolonged second stage of labor (OR = 1.01; 95% CI: 1.01–1.01). A protective factor against the use of an episiotomy was delivery in the Birth Centre (OR = 0.43; 95% CI: 0.37–0.51) and mulitpara (OR = 0.31; 95% CI: 0.27–0.35). To reduce the frequency of an episiotomy, it is necessary consider the risk factors of performing this procedure in everyday practice, e.g., limiting the use of oxytocin or promoting alternative places of delivery. Full article
(This article belongs to the Section Obstetrics & Gynecology)
12 pages, 785 KB  
Article
Spontaneous Perineal Trauma during Non-Operative Childbirth—Retrospective Analysis of Perineal Laceration Risk Factors
by Grażyna Bączek, Ewa Rzońca, Dorota Sys, Sylwia Rychlewicz, Anna Durka, Patryk Rzońca and Agnieszka Bień
Int. J. Environ. Res. Public Health 2022, 19(13), 7653; https://doi.org/10.3390/ijerph19137653 - 23 Jun 2022
Cited by 13 | Viewed by 6856
Abstract
Childbirth-related perineal trauma (CRPT) is defined as damage to the skin, muscles of the perineum, as well as to the anal sphincter complex and anal epithelium. The aim of the study was to analyze the risk factors for spontaneous injuries to the soft [...] Read more.
Childbirth-related perineal trauma (CRPT) is defined as damage to the skin, muscles of the perineum, as well as to the anal sphincter complex and anal epithelium. The aim of the study was to analyze the risk factors for spontaneous injuries to the soft tissues of the birth canal during non-operative delivery. This was a single-center retrospective case-control study. The study included the analysis of two groups, the study group featured 7238 patients with spontaneous perineal laceration (any degree of perineal laceration) and the control group featured patients without perineal laceration with 7879 cases. The analysis of single-factor logistic regression showed that the factors related to perineal laceration during childbirth are the age of the patients giving birth (p = 0.000), the BMI before delivery (p = 0.000), the number of pregnancies (p = 0.000) and deliveries (p = 0.000), diagnosed gestational diabetes (p = 0.046), home birth (p = 0.000), vaginal birth after cesarean (VBAC) (p = 0.001), the use of oxytocin in the second stage of childbirth (p = 0.041), the duration of the second stage of childbirth (p = 0.000), body weight (p = 0.000), and the circumference of the newborn head (p = 0.000). Independent factors that increase the risk of perineal laceration during childbirth are an older age of the woman giving birth, a history of cesarean section, a higher birth weight of the newborn, and factors that reduce the risk of spontaneous perineal trauma are a higher number of deliveries and home birth. Full article
(This article belongs to the Special Issue Research on Maternal and Reproductive Health)
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