Search Results (35,913)

Corporate financial policy requires managers to balance financing, investment, and payout decisions while maintaining sufficient financial flexibility to respond to unexpected shocks and investment opportunities. Despite the importance of financial flexibility, limited empirical evidence exists on its determinants in African capital markets. Using panel data from 106 non-financial firms listed on the Johannesburg Stock Exchange over the period 2000–2019, this study examines the determinants of financial flexibility. Financial flexibility is identified by comparing actual and predicted leverage and classifying firms with persistent spare debt capacity as financially flexible. The main empirical model is estimated as a random-effects linear probability model with heteroscedasticity-robust standard errors. The results show that financial flexibility is significantly negatively associated with leverage and Tobin’s Q, indicating that firms with higher debt levels and stronger growth opportunities are less likely to preserve borrowing capacity. Retained earnings and financing cost show weak negative associations at the 10% significance level, while dividend payout, profitability, cash holdings, and tangibility are statistically insignificant. The study contributes to the corporate finance literature by providing new evidence from an African emerging market context, incorporating payout policy into the financial flexibility framework, and showing how leverage discipline and growth-related financing demands shape firms’ financial flexibility. Full article

Intensive ornamental planting is increasingly prevalent in urban green spaces, yet its effects on soil microbial community assembly and interaction networks remain poorly understood. Here, we examined shifts in soil properties, microbial diversity, community composition, and interaction networks across successive planting cycles. Bacterial alpha-diversity remained relatively stable, whereas fungal communities showed pronounced sensitivity to early planting stages. Beta-diversity analyses revealed that bacterial community composition was jointly influenced by planting stage and site type, while fungal communities were primarily structured by site characteristics. Co-occurrence network analysis revealed contrasting reassembly trajectories between microbial groups. Bacterial networks exhibited increasing complexity and modularity, indicating enhanced interaction intensity and competitive structuring under intensive management. In contrast, fungal networks displayed reduced connectivity but maintained or recovered modular organization, suggesting structural buffering. Notably, keystone taxa remained taxonomically conserved, indicating that network reorganization was driven by interaction rewiring rather than species turnover. We propose a dual-speed reassembly framework in which bacteria function as fast-responding components with dynamic interaction networks, whereas fungi act as slow-buffering, structurally persistent elements. This decoupling of short-term functional responsiveness and long-term stability provides new insights into how intensive management reshapes soil microbiomes in botanical garden ecosystems. Full article

This study illuminates fundamental questions in behavioral science through advanced machine learning methodologies applied to large-scale public opinion data. Drawing on Kahneman and Tversky’s dual-process theory and Sunstein’s nudge architecture, we employ hierarchical unsupervised clustering and supervised predictive models to detect cognitive biases—loss aversion, availability heuristic, and partisan motivated reasoning—embedded within a nationally representative survey of 5022 American respondents. Our primary methodological contribution is a hierarchical two-stage clustering framework that uncovers latent opinion structures without imposing a priori partisan categories, permitting discovery of cross-cutting cleavages invisible to conventional survey analysis. Three principal findings emerge: (1) loss aversion is empirically confirmed in prospective economic perception, with pessimists outnumbering optimists at a 1.14:1 ratio even among respondents rating current conditions positively; (2) partisan motivated reasoning produces a 13.15 percentage-point perception gap among individuals with identical financial circumstances; and (3) multi-platform digital engagement is associated with reduced partisan bias, providing evidence that challenges simple echo chamber assumptions. Crime safety perception emerges as the strongest predictor of economic bias, surpassing party affiliation, and substantiating availability heuristic dominance in political cognition. These findings carry implications for democratic accountability, platform governance, and the ethics of AI-augmented behavioral analysis in an era of affective polarization. Full article

This study adopts the theory of planned behavior to investigate consumers’ purchasing decisions under extreme weather conditions. Specifically, this paper examines how extreme global weather events motivate consumers to consider purchasing green products and prioritize environmental sustainability in their consumption choices. It further explores whether consumers’ adoption of green products enhances their satisfaction under abnormal global climate conditions, as well as how consumer satisfaction subsequently improves individuals’ mood, anxiety, and cognitive states. Structural equation modeling was employed to test the hypothesized model using data collected from 352 valid respondents in China. As the global community strives to achieve net-zero CO₂ emissions by 2050, numerous firms and manufacturers have incorporated green product concepts to advance sustainable operations. The empirical results reveal that anxiety and cognition are positively related to green purchasing decisions, which in turn exert a positive influence on consumer satisfaction. Based on these findings, this study proposes actionable strategies to promote green consumption behavior by accounting for relevant psychological factors. Full article

This study examines how users’ preferences for spatial elements in neighborhood parks influence satisfaction and assesses the moderating role of urban density in this relationship. An online survey was conducted with 283 residents in the Seoul Metropolitan Area, and the study area was classified into high-, medium-, and low-density urban contexts. Exploratory factor analysis was employed to derive key spatial elements, and multiple regression and moderation analyses were conducted to empirically verify the relationship between the respondents’ spatial preferences and satisfaction. The study finds that the spatial elements of neighborhood parks have significantly varying effects on user satisfaction based on urban density. Specifically, natural and community spaces were identified as core elements that consistently influenced satisfaction across all urban density levels. In contrast, multifunctional cultural spaces were the only significant predictors of the relationship between spatial preferences and satisfaction in high-density spaces and urban-landscape spaces only had a significant influence in medium-density areas. The findings suggest that the spatial elements of neighborhood parks do not operate universally; rather, their effects on user satisfaction are context-dependent and shaped by urban density. Full article

Olive cultivation represents a key pillar of rural economies and cultural heritage in Mediterranean regions, including western Greece. Despite its socio-economic importance, the sector faces increasing pressures from climate change, market volatility, and technological transformation, while progress toward environmentally sustainable production remains uneven. This study investigates how olive farmers’ perceptions of carbon footprint and climate risks are influenced by their demographic characteristics. Primary data were collected through 402 structured questionnaires distributed to olive producers in the Aetolia–Acarnania region. The sample was designed to represent farmers directly engaged in olive production, ensuring the relevance and reliability of the collected data. The findings, based on descriptive statistics, reveal significant heterogeneity in producers’ perceptions of climate risks and their capacity to respond through sustainable practices. Demographic characteristics appear to play an important role in shaping awareness of carbon footprint and the potential adoption of environmentally responsible farming strategies. These results suggest that sustainability transitions in perennial cropping systems depend not only on technological availability but also on social, informational, and institutional capacities. Strengthening agricultural advisory services, farmer training, and climate adaptation strategies may therefore support the adoption of climate-smart practices in olive cultivation. Furthermore, cooperation and value-chain integration are identified as potentially important mechanisms for facilitating knowledge transfer and supporting the adoption of sustainable practices (e.g., efficient irrigation and optimized input use). However, their contribution to environmental performance and greenhouse gas mitigation cannot be directly inferred from the present perception-based analysis and should be examined in future research using appropriate quantitative or environmental assessment frameworks. Full article

Background: Tension-type headache (TTH) is the most prevalent primary headache disorder worldwide and represents a major source of disability related to chronic pain. Despite its high prevalence, uncertainty remains regarding optimal conservative management strategies, and limited evidence is available on how physiotherapists apply existing recommendations in routine clinical practice. Objective: The objective was to explore physiotherapists’ perceptions, clinical experiences, and treatment strategies in the management of tension-type headache, with particular emphasis on commonly used interventions, clinical decision-making, and characteristics of physiotherapy care. Methods: A cross-sectional survey study was conducted using a self-administered online survey developed in accordance with the CHERRIES guidelines. One hundred Spanish physiotherapists with clinical experience in treating patients with TTH participated. Quantitative data were analyzed descriptively, while open-ended responses were examined using inductive thematic analysis following the framework proposed by Braun and Clarke. Results: Manual therapy was the most frequently reported intervention (96%), followed by therapeutic exercise (61%) and invasive techniques, primarily dry needling (48%). The suboccipital and upper cervical regions were consistently identified as primary therapeutic targets, reflecting a predominant craniocervical treatment focus. Most respondents reported individualized treatment plans, typically delivered in weekly sessions lasting 45–60 min, with expected clinical improvement within 4–6 weeks. Pain education strategies were reported infrequently. Considerable variability was observed in the selection and combination of therapeutic techniques. Conclusions: Physiotherapists managing tension-type headache commonly adopt a multimodal approach, largely centered on manual and tissue-focused interventions. Although many reported practices are aligned with current evidence, the substantial heterogeneity observed and the limited integration of biopsychosocial strategies highlight the need for consensus-based guidelines and further research addressing real-world clinical effectiveness. Full article

The accelerated aging of the population in vulnerable urban contexts poses significant challenges for architecture, particularly with regard to the quality of life of older adults. Within this framework, the present study aimed to analyze the association between sensory architecture and the quality of life of older adults and to translate this empirical evidence into context-informed design criteria for the development of a comprehensive center for older adults. The study adopted a quantitative approach with a non-experimental, cross-sectional, and correlational design. A structured questionnaire on sensory architecture and quality of life was administered to family members and caregivers acting as proxy respondents, demonstrating high internal consistency (Cronbach’s $\mathit{\alpha }>0.90$). Given the ordinal nature of the data, inferential analysis was conducted using Spearman’s rho coefficient. Within the analyzed dataset, the results revealed a statistically significant and strong association between sensory architecture and the quality of life of older adults ($\rho$ > 0.80). At the dimensional level, visual and tactile stimuli exhibited the highest associations, followed by the social relationships dimension, while therapeutic environments showed a moderate association, allowing the identification of an empirical hierarchy among the analyzed dimensions within this dataset. These findings support the interpretation of sensory architecture as a construct statistically associated with indicators of quality of life, from a non-causal perspective. Based on this hierarchy, the results were articulated into an evidence-based architectural structure, serving as analytical input to inform context-specific criteria for spatial organization, materiality, comfort, orientation, and social interaction derived from the observed statistical associations. The study contributes a methodological approach that systematically connects correlational quantitative findings with architectural design considerations, particularly in urban contexts characterized by limited specialized infrastructure. However, a key limitation is the use of proxy respondents (family members and caregivers), which should be considered when interpreting the results. Full article

Animal by-products (ABPs), comprising both edible and inedible components, offer significant nutritional, economic, and environmental value. However, their utilization differs markedly across global jurisdictions due to cultural preferences, regulatory frameworks, and technological capacities, which collectively shape consumption patterns and determine integration into food systems or diversion to industrial applications. While consumer reliance on offal remains high in the Global South, driven by tradition, affordability, and nutritional needs, its acceptance in the Global North is markedly lower, often limited by cultural aversion and perceived risks. Drawing from published evidence and primary survey data, this review examines regional consumption trends, industrial utilization pathways, and emerging valorization opportunities for ABPs. Globally, industrial use of ABPs is increasingly shifting toward advanced bioprocessing, integration within circular bioeconomy models, and high-value applications in nutraceutical, pharmaceutical, and bio-industrial sectors. An online cross-sectional survey (n = 358) conducted across Africa, North America, Europe, and Asia revealed strong regional disparities in offal consumption, with higher acceptance in parts of Africa and Asia and more selective use in Europe and North America. Respondents also indicated clear support for non-food valorization pathways, particularly animal feed, fertilizer, and energy production, alongside pharmaceutical and cosmetic applications. These findings align with the literature, where industrial valorization pathways such as collagen and gelatin extraction, rendering, and bioenergy production dominate. This review synthesized the jurisdictional disparities in consumption, regulation, technological capability, and industrial applications while highlighting emerging technological opportunities for high-value valorization. Recommendations emphasize consumer education, regulatory refinement, technological innovation, and sustainable practices to enhance the economic and environmental benefits of ABP utilization within a circular bioeconomy framework. Full article

Background: Healthcare policy in the United Kingdom recognizes that teenagers and young adults (TYAs: 16–24 years at diagnosis) require specialist care. In England, Principal Treatment Centers (PTCs) exist, delivering enhanced care exclusively within the PTC or as ‘joint care’ with designated hospitals (DHs). Central to this is the TYA multidisciplinary team (MDT) and an outreach model coordinating care between hospitals. We previously reported similar outcomes regardless of care location. Aims: To compare TYA experiences of care with healthcare professionals’ perspectives of the service they deliver. Methods: Mixed methods across England and Wales were used. The TYA-MDT identified TYAs who then received a postal invite to a cross-sectional survey capturing experiences of places of care, treatment, healthcare professional support (HCP), mental health, sexuality/fertility, clinical trials and care coordination. Comparisons were made based on exposure to care in a specialist TYA environment within 6 months of diagnosis: all-TYA-PTC (all care in the TYA-PTC, n = 70, 28%), no-TYA-PTC (no care in the TYA-PTC (n = 87, 35%): care delivered in a children/adult unit only), and joint care (care in a TYA-PTC and in a children’s/adult unit, n = 91, 36%). HCP perspectives were captured by rapid ethnography. Results: A total of 250/1056 (24%) TYAs participated. Overall, 200 (80%) rated their teams as excellent/good for helping them prepare for treatment. No evidence of significant differences existed between categories of care for proportions receiving support from key TYA-related professionals: TYA cancer nurse specialists (all-TYA-PTC n = 58, 91%; joint care n = 71, 88%; no-TYA-PTC n = 64, 82%) and social workers (all-TYA-PTC n = 30, 55%; joint care n = 36, 48%; no-TYA-PTC n = 28, 38%). A trend of diminishing support from youth support co-coordinators existed (all-TYA-PTC 63%; joint care 49%; no-TYA-PTC 40%, p = 0.069). This may explain why few differences in patient experiences existed across categories of care. Forty-nine HCPs participated. They were more critical in their interpretation of care, highlighting inequity in resources and challenges in some pathways and coordination. Conclusions: Similar access to age-appropriate support across care settings is likely to reflect recruitment methods. When TYAs are known to the MDT, age-appropriate care can be mobilized beyond TYA units, which could explain the equitable outcomes observed across different care locations in young people who responded to the survey. Nevertheless, gaps persist in communication and coordination, particularly within joint care models, and in the involvement of allied health professionals such as dieticians and physiotherapists, whose input is essential for rehabilitation and return to normal life. Strengthening these areas will require continued investment in workforce capacity and digital infrastructure to support genuinely coordinated, developmentally appropriate TYA cancer care. Full article

Knowledge sharing (KS) among healthcare professionals is essential for sustaining organisational learning and facilitating the transfer of expertise between experienced and less experienced professionals, thereby supporting workforce stability and retention in healthcare organisations (HCOs). However, despite its importance, high turnover among healthcare professionals remains a significant and persistent challenge in public HCOs, indicating a potential gap in understanding the mechanisms that support workforce stability. To address this gap, this study examines the interplay between work performance (WP), satisfaction with co-workers (CW), KS and turnover intention (TI) among healthcare professionals. Data from 220 respondents were analysed using Partial Least Squares Structural Equation Modelling (PLS-SEM) within the Input–Process–Output (IPO) framework. The results indicate that CW positively influences KS, while KS has a negative effect on TI, thereby reducing TI. In contrast, WP does not have a statistically significant effect on KS, nor does it indirectly influence TI through KS. Furthermore, although both WP and CW were hypothesised to be predictors of KS, only CW demonstrates a significant indirect effect on TI through KS. Grounded in Social Exchange Theory (SET) and the Knowledge-Based View (KBV), the results highlight the role of KS and interpersonal relationships in supporting sustainable human resource management (SHRM). Although sustainability-related dimensions were not directly measured, the results suggest potential implications for the Sustainable Development Goals (SDGs), particularly SDG 3, SDG 8, and SDG 9. Full article

The effects of progressive drought stress were examined in four economically important plant species belonging to the Lamiaceae family: catnip (Nepeta cataria L.), lavender (Lavandula angustifolia Mill.), holy basil (Ocimum tenuiflorum L.), and perilla mint (Perilla frutescens (L.) Britton). Plants were grown in a controlled pot experiment under three soil water capacity levels: 70% (control), 50% (moderate stress), and 30% (severe stress), and the drought stress lasted for 30 days. The study evaluated a comprehensive set of leaf micromorphological parameters, including the density and diameter of glandular trichomes, stomatal density and size, and the thickness of the lamina, mesophyll, epidermis, cuticle, and parenchymal layers. In addition, essential oil (EO) content, total flavonoid content (TFC), and elemental composition were analyzed. Drought responses were strongly species-specific. O. tenuiflorum, P. frutescens, and N. cataria showed high sensitivity characterized by reduced biomass and thinning of leaf tissues. These changes were accompanied by typical xeromorphic adaptations, such as increased stomatal and glandular trichome density, and reduced stomatal size. L. angustifolia exhibited pronounced cuticle thickening, suggesting an effective structural mechanism to minimize water loss. Secondary metabolism also responded differently among species. In some cases, drought shifted metabolic allocation toward flavonoid accumulation at the expense of essential oils, whereas in others, moderate stress promoted the co-accumulation of both compounds. These patterns indicate distinct adaptive strategies linking anatomical plasticity with metabolic regulation. Overall, moderate drought supported adaptive responses, while severe water limitation impaired growth and metabolic production. From a practical perspective, maintaining moderate soil water availability appears critical to optimize both plant performance and the accumulation of valuable secondary metabolites in Lamiaceae species. Full article

Immune checkpoint inhibitors (ICIs) have revolutionized the therapeutic landscape for hepatocellular carcinoma (HCC); however, a considerable proportion of patients do not achieve durable clinical benefits. This highlights the need for reliable predictive biomarkers, which are currently lacking. The accumulated evidence supports a relevant role of the gut–liver axis in modulating immunotherapy outcomes, and several studies have identified distinct microbial features associated with either responders or non-responders. Responders to immunotherapy frequently present with higher microbial diversity and enrichment of beneficial taxa, whereas the expansion of pro-inflammatory and pathogenic bacteria has been associated with primary resistance and increased treatment-related toxicity in non-responders. However, the available findings remain heterogeneous across cohorts, likely owing to differences in geography, diet, liver disease etiology, treatment regimens, and microbiome analytical methods. Machine-learning models integrating metagenomic and metabolomic data have shown encouraging results in defining microbial signatures associated with treatment outcomes, although variability among cohorts currently limits their clinical applicability and generalizability. Beyond microbial taxonomic composition, microbiota-derived metabolites—such as short-chain fatty acids, bile acids, inosine, and tryptophan catabolites—appear to play a crucial role in shaping the tumor microenvironment and host immune responses, thus representing additional candidate biomarkers, also due to the relative ease of their measurement. Finally, microbiota-targeted interventions are emerging as potential strategies to enhance immunotherapy efficacy. Overall, the gut microbiome and its metabolic activity represent promising tools, albeit still under investigation, for patient stratification and personalized management in HCC treated with ICIs. Therefore, this review aims to summarize and critically discuss the current evidence on gut microbiota-derived biomarkers of response and resistance to ICIs in HCC, with particular focus on microbial composition, microbiota-related metabolites, and emerging microbiome-based therapeutic strategies. This narrative review provides an updated overview of the role of gut microbiota as both a biomarker and a therapeutic target in patients with hepatocellular carcinoma (HCC) receiving immune checkpoint inhibitor (ICI) therapy. Full article

Traditional ecological knowledge (TEK) is cardinal to natural resource management, and its resilience in protected areas (PAs) depends on its continued practice. The changing socio-ecological landscape has given rise to new PAs that emphasise community participation, like Simalaha Community Conservancy (SCC), versus state-owned, like Liuwa Plain National Park (LPNP). Resilience was assessed by comparing TEK awareness, utilisation, and perceived effectiveness between LPNP and SCC. Three categories of TEK (rules and regulations; myths and taboos; and customs and rituals) were analysed using a blended analytical framework drawing on the knowledge–practice–belief complex and a social–ecological systems perspective. A structured questionnaire was administered to 427 respondents, and data were analysed using descriptive statistics and chi-square tests. TEK awareness was high, but significantly higher in LPNP than in SCC. Age and length of residence were strongly associated with knowledge, confirming older and long-term residents as key knowledge-holders. Rules and regulations were widely recognised and utilised, while customs and rituals, and myths and taboos, were variable. LPNP showed higher utilisation and perceived effectiveness of TEK, particularly among younger cohorts. These findings highlight the influence of conservation governance and intergenerational knowledge transmission on TEK resilience, underscoring the need to strengthen its integration in emerging PAs. Full article

Food waste in households means that there is a need to recognize the possibilities of balancing activities in the field of obtaining and managing food products. Activities in this area may concern giving away surplus food to others, purchasing local and organic products, limiting shopping activity. Generation Z, which was included in this research, uses new media, including mobile applications, to a greater extent than other generations. The main objective of the research is to recognize and present the food-sustainable behaviors and attitudes of Generation Z consumers. The study used the analysis of source data, which was the basis for formulating four hypotheses. They were verified in empirical studies conducted using the CAWI method. The collected material was analyzed using, among others, the proprietary index of environmentally and socially sustainable behaviors (ESRBI), the Mann-Whitney test. The studies showed that respondents assessed their food behaviors as irresponsible, with women’s assessment being higher than men’s. A positive correlation was demonstrated between the use of food saving applications and the value of the ESRBI index and individual sustainable behaviors. Respondents positively assessed the initiatives of local authorities and housing cooperatives in the area of creating places for sharing food and organizing community gardens. Full article