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Keywords = production-to-demand mismatch

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29 pages, 21087 KiB  
Article
Multi-Scale Ecosystem Service Supply–Demand Dynamics and Driving Mechanisms in Mainland China During the Last Two Decades: Implications for Sustainable Development
by Menghao Qi, Mingcan Sun, Qinping Liu, Hongzhen Tian, Yanchao Sun, Mengmeng Yang and Hui Zhang
Sustainability 2025, 17(15), 6782; https://doi.org/10.3390/su17156782 - 25 Jul 2025
Viewed by 254
Abstract
The growing mismatch between ecosystem service (ES) supply and demand underscores the importance of thoroughly understanding their spatiotemporal patterns and key drivers to promote ecological civilization and sustainable development at the regional level in China. This study investigates six key ES indicators across [...] Read more.
The growing mismatch between ecosystem service (ES) supply and demand underscores the importance of thoroughly understanding their spatiotemporal patterns and key drivers to promote ecological civilization and sustainable development at the regional level in China. This study investigates six key ES indicators across mainland China—habitat quality (HQ), carbon sequestration (CS), water yield (WY), sediment delivery ratio (SDR), food production (FP), and nutrient delivery ratio (NDR)—by integrating a suite of analytical approaches. These include a spatiotemporal analysis of trade-offs and synergies in supply, demand, and their ratios; self-organizing maps (SOM) for bundle identification; and interpretable machine learning models. While prior research studies have typically examined ES at a single spatial scale, focusing on supply-side bundles or associated drivers, they have often overlooked demand dynamics and cross-scale interactions. In contrast, this study integrates SOM and SHAP-based machine learning into a dual-scale framework (grid and city levels), enabling more precise identification of scale-dependent drivers and a deeper understanding of the complex interrelationships between ES supply, demand, and their spatial mismatches. The results reveal pronounced spatiotemporal heterogeneity in ES supply and demand at both grid and city scales. Overall, the supply services display a spatial pattern of higher values in the east and south, and lower values in the west and north. High-value areas for multiple demand services are concentrated in the densely populated eastern regions. The grid scale better captures spatial clustering, enhancing the detection of trade-offs and synergies. For instance, the correlation between HQ and NDR supply increased from 0.62 (grid scale) to 0.92 (city scale), while the correlation between HQ and SDR demand decreased from −0.03 to −0.58, indicating that upscaling may highlight broader synergistic or conflicting trends missed at finer resolutions. In the spatiotemporal interaction network of supply–demand ratios, CS, WY, FP, and NDR persistently show low values (below −0.5) in western and northern regions, indicating ongoing mismatches and uneven development. Driver analysis demonstrates scale-dependent effects: at the grid scale, HQ and FP are predominantly influenced by socioeconomic factors, SDR and WY by ecological variables, and CS and NDR by climatic conditions. At the city level, socioeconomic drivers dominate most services. Based on these findings, nine distinct supply–demand bundles were identified at both scales. The largest bundle at the grid scale (B3) occupies 29.1% of the study area, while the largest city-scale bundle (B8) covers 26.5%. This study deepens the understanding of trade-offs, synergies, and driving mechanisms of ecosystem services across multiple spatial scales; reveals scale-sensitive patterns of spatial mismatch; and provides scientific support for tiered ecological compensation, integrated regional planning, and sustainable development strategies. Full article
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20 pages, 8970 KiB  
Article
Sparing or Sharing? Differential Management of Cultivated Land Based on the “Landscape Differentiation–Function Matching” Analytical Framework
by Guanyu Ding and Huafu Zhao
Land 2025, 14(6), 1278; https://doi.org/10.3390/land14061278 - 14 Jun 2025
Viewed by 473
Abstract
The sole function of cultivated land of agricultural production is insufficient to meet the diverse demands of modern agriculture. To address land-use conflicts and achieve the United Nations Sustainable Development Goals (SDGs) of zero hunger and reduced carbon emissions by 2030, this study [...] Read more.
The sole function of cultivated land of agricultural production is insufficient to meet the diverse demands of modern agriculture. To address land-use conflicts and achieve the United Nations Sustainable Development Goals (SDGs) of zero hunger and reduced carbon emissions by 2030, this study introduces the theory of land sparing and sharing, uses landscape indices to identify spatially fragmented areas, employs a four-quadrant model to assess the matching status of functional supply and demand, and applies correlation analysis to determine the trade-off/synergy relationships between functions. The results indicate the following: (1) Zhengzhou’s farmland landscape exhibits characteristics of low density, low continuity, and high aggregation, with separation zones and sharing zones accounting for 77% and 23% of the total farmland area, respectively. (2) The multifunctional supply (high in the northeast, low in the southwest) and demand (high in the west, low in the east) of farmland show significant mismatches, with PF and EF exhibiting the most pronounced supply–demand mismatches. The “LS-LD and HS-LD” types of farmland account for the largest proportions, at 39% and 35%, respectively. (3) The study area is divided into four primary types: “PCZ, RLZ, BDZ, and MAZ” to optimize supply–demand relationships and utilization patterns. This study enriches the application of land sparing and sharing in related fields, providing important references for policymakers in optimizing land-use allocation and balancing food and ecological security. Full article
(This article belongs to the Section Land Use, Impact Assessment and Sustainability)
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35 pages, 24700 KiB  
Article
Optimizing Load Frequency Control of Multi-Area Power Renewable and Thermal Systems Using Advanced Proportional–Integral–Derivative Controllers and Catch Fish Algorithm
by Saleh A. Alnefaie, Abdulaziz Alkuhayli and Abdullah M. Al-Shaalan
Fractal Fract. 2025, 9(6), 355; https://doi.org/10.3390/fractalfract9060355 - 29 May 2025
Viewed by 646
Abstract
Renewable energy sources (RESs) are increasingly combined into the power system due to market liberalization and environmental and economic benefits, but their weather-dependent variability causes power production and demand mismatches, leading to issues like frequency and regional power transmission fluctuations. To maintain synchronization [...] Read more.
Renewable energy sources (RESs) are increasingly combined into the power system due to market liberalization and environmental and economic benefits, but their weather-dependent variability causes power production and demand mismatches, leading to issues like frequency and regional power transmission fluctuations. To maintain synchronization in power systems, frequency must remain constant; disruptions in the proper balance of production and load might produce frequency variations, risking serious issues. Therefore, a mechanism known as load frequency control (LFC) or automated generation control (AGC) is needed to keep the frequency and tie-line power within predefined stable limits. In this study, advanced proportional–integral–derivative PID controllers such as fractional-order PID (FOPID), cascaded PI(PDN), and PI(1+DD) for LFC in a two-area power system integrated with RES are optimized using the catch fish optimization algorithm (CFA). The controllers’ optimal gains are attained through using the integral absolute error (IAE) and ITAE objective functions. The performance of LFC with CFA-tuned PID, PI, cascaded PI(PDN), and FOPID, PI(1+DD) controllers is compared to other optimization techniques, including sine cosine algorithm (SCA), particle swarm optimization (PSO), brown bear algorithm (BBA), and grey wolf optimization (GWO), in a two-area power system combined with RESs under various conditions. Additionally, by contrasting the performance of the PID, PI, cascaded PI(PDN), and FOPID, PI(1+DD) controllers, the efficiency of the CFA is confirmed. Additionally, a sensitivity analysis that considers simultaneous modifications of the frequency bias coefficient (B) and speed regulation (R) within a range of ±25% validates the efficacy and dependability of the suggested CFA-tuned PI(1+DD). In the complex dynamics of a two-area interconnected power system, the results show how robust the suggested CFA-tuned PI(1+DD) control strategy is and how well it can stabilize variations in load frequency and tie-line power with a noticeably shorter settling time. Finally, the results of the simulation show that CFA performs better than the GWO, BBA, SCA, and PSO strategies. Full article
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23 pages, 1977 KiB  
Article
The Gamma Distribution and Inventory Control: Disruptive Lead Times Under Conventional and Nonclassical Conditions
by John E. Tyworth
Logistics 2025, 9(2), 67; https://doi.org/10.3390/logistics9020067 - 27 May 2025
Cited by 1 | Viewed by 898
Abstract
Background: Foundational research on the gamma distribution and inventory control highlighted its flexibility and practicality for managing fast-moving finished goods. Nonetheless, concerns remain about conventional statistical approximations of lead-time demand (LTD) distributions. Real-world lead times often result in nonstandard LTD forms, and [...] Read more.
Background: Foundational research on the gamma distribution and inventory control highlighted its flexibility and practicality for managing fast-moving finished goods. Nonetheless, concerns remain about conventional statistical approximations of lead-time demand (LTD) distributions. Real-world lead times often result in nonstandard LTD forms, and traditional methods may introduce parameter mismatches under nonclassical conditions. Despite these challenges, this research demonstrates that a gamma LTD approximation is an effective method for managing these goods. Methods: This study employs numerical experiments to assess accuracy at high service levels, focusing on errors in system cost and product availability. Three propositions are validated: (1) a standard distribution generally characterizes the demands of fast-moving items; (2) demand variability systematically modifies the form of nonstandard LTD distributions, enhancing accuracy; (3) nonclassical conditions generally improve the accuracy of properly parameterized gamma approximations. A purposive sample of disruptive lead-time distributions found in global maritime supply chains drives numerical experiments. Results: Externally validated evidence provides the following findings within our study context: (1) a nonstandard lead-time distribution does not necessarily result in a similar LTD distribution, as it also depends on demand variability; (2) demand variability positively affects the form of a nonstandard LTD distribution under conventional conditions, with nonclassical conditions enhancing this effect; (3) the shape transformations almost always improve the accuracy of a gamma approximation. Conclusions: A gamma LTD approximation can manage inventory for fast-moving finished goods effectively, even with disruptive lead times under both conventional and nonclassical conditions. Full article
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26 pages, 9582 KiB  
Article
Influencing Factors and Paths of the Coupling Relationship Between Ecosystem Services Supply–Demand and Human Well-Being in the Hexi Regions, Northwest China
by Yongge Li, Wei Liu, Meng Zhu, Qi Feng, Linshan Yang, Jutao Zhang, Zhenliang Yin and Xinwei Yin
Remote Sens. 2025, 17(10), 1787; https://doi.org/10.3390/rs17101787 - 20 May 2025
Viewed by 580
Abstract
The coupling coordination relationship between ecosystem services supply–demand and human well-being in arid inland regions is increasingly vulnerable to imbalance risks under the combined pressures of climate change and intensified anthropogenic activities. Here, we assessed dynamic changes in ecosystem services supply–demand, human well-being, [...] Read more.
The coupling coordination relationship between ecosystem services supply–demand and human well-being in arid inland regions is increasingly vulnerable to imbalance risks under the combined pressures of climate change and intensified anthropogenic activities. Here, we assessed dynamic changes in ecosystem services supply–demand, human well-being, their coupling relationships and influencing factors in the Hexi Regions by integrating remote sensing data, ecological model, ecosystem services supply–demand ratio (ESDR), coupling coordination degree (CCD) model, and the partial least squares structural equation modeling (PLS-SEM). Our results showed that the six key ecosystem services supply, demand, and ESDR in the Hexi Regions from 1990 to 2020 exhibited greater ecosystem services surplus in the Qilian Mountains and stronger deficits in urban and surrounding areas of the Hexi Corridor. The deficit of water yield accounted for 32% in the Hexi Corridor with large cropland irrigated, four times that of the Qilian Mountains, indicating a serious supply–demand mismatch in space and time. Additionally, survival-oriented human well-being across regions is still dominant. Overall, the coupling relationship between ESDR and human well-being in the Hexi Regions progressed towards a high level of coordination, with higher values observed in the oases of the Hexi Corridor and the central and eastern Qilian Mountains. The ESDR of food production and water yield showed a higher coupling coordination level with human well-being in the Qilian Mountains, where the CCD was generally exceeded by 0.7. Climate, vegetation, and land use intensity were key drivers of spatial heterogeneity in CCD. Human well-being made a greater contribution to CCD than other elements in the influence paths. Our results can provide a reference for promoting coordinated development of the ecological environment and sustainable human well-being in arid inland regions. Full article
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23 pages, 5215 KiB  
Article
Experimental Evaluation of Hybrid Renewable and Thermal Energy Storage Systems for a Net-Zero Energy Greenhouse: A Case Study of Yeoju-Si
by Misbaudeen Aderemi Adesanya, Anis Rabiu, Qazeem Opeyemi Ogunlowo, Min-Hwi Kim, Timothy Denen Akpenpuun, Wook-Ho Na, Kuljeet Singh Grewal and Hyun-Woo Lee
Energies 2025, 18(10), 2635; https://doi.org/10.3390/en18102635 - 20 May 2025
Viewed by 565
Abstract
The implementation of renewable energy systems (RESs) in the agricultural sector has significant potential to mitigate the negative effects of fossil fuel-based products on the global climate, reduce operational costs, and enhance crop production. However, the intermittent nature of RESs poses a major [...] Read more.
The implementation of renewable energy systems (RESs) in the agricultural sector has significant potential to mitigate the negative effects of fossil fuel-based products on the global climate, reduce operational costs, and enhance crop production. However, the intermittent nature of RESs poses a major challenge to realizing these benefits. To address this, thermal energy storage (TES) and hybrid heat pump (HHP) systems are integrated with RESs to balance the mismatch between thermal energy production and demand. In pursuit of clean energy solutions in the agricultural sector, a 3942 m2 greenhouse in Yeoju-si, South Korea, is equipped with 231 solar thermal (ST) collectors, 117 photovoltaic thermal (PVT) collectors, four HHPs, two ground-source heat pumps (GSHPs), a 28,500 m3 borehole TES (BTES) unit, a 1040 m3 tank TES (TTES) unit, and three short-term TES units with capacities of 150 m3, 30 m3, and 30 m3. This study evaluates the long-term performance of the integrated hybrid renewable energy and thermal energy storage systems (HRETESSs) in meeting the greenhouse’s heating and cooling demands. Results indicate that the annual system performance efficiencies range from 25.3% to 68.5% for ST collectors and 31.9% to 72.2% for PVT collectors. The coefficient of performance (COP) during the heating season is 3.3 for GSHPs, 2.5 for HHPs using BTES as a source, and 3.6 for HHPs using TTES as a source. During the cooling season, the COP ranges from 5.3 to 5.7 for GSHPs and 1.84 to 2.83 for ASHPs. Notably, the HRETESS supplied 3.4% of its total heating energy directly from solar energy, 89.3% indirectly via heat pump utilization, and 7.3% is provided by auxiliary heating. This study provides valuable insights into the integration of HRETESSs to maximize greenhouse energy efficiency and supports the development of sustainable agricultural energy solutions, contributing to reduced greenhouse gas emissions and operational costs. Full article
(This article belongs to the Section B: Energy and Environment)
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21 pages, 5080 KiB  
Article
Sustainable Dynamic Scheduling Optimization of Shared Batteries in Urban Electric Bicycles: An Integer Programming Approach
by Zongfeng Zou, Xin Yan, Pupu Liu, Weihao Yang and Chao Zhang
Sustainability 2025, 17(10), 4379; https://doi.org/10.3390/su17104379 - 12 May 2025
Viewed by 472
Abstract
With the proliferation of electric bicycle battery swapping models, spatial supply demand imbalances of battery resources across swapping stations have become increasingly prominent. Existing studies predominantly focus on location optimization but struggle to address dynamic operational challenges in battery allocation efficiency. This paper [...] Read more.
With the proliferation of electric bicycle battery swapping models, spatial supply demand imbalances of battery resources across swapping stations have become increasingly prominent. Existing studies predominantly focus on location optimization but struggle to address dynamic operational challenges in battery allocation efficiency. This paper proposes an integer programming (IP)-based dynamic scheduling optimization method for shared batteries, aiming to minimize transportation costs and balance battery distribution under multi-constraint conditions. A resource allocation model is constructed and solved via an interior-point method (IPM) combined with a branch-and-bound (B&B) strategy, optimizing the dispatch paths and quantities of fully charged batteries among stations. This study contributes to urban sustainability by enhancing resource utilization efficiency, reducing redundant production, and supporting low-carbon mobility infrastructure. Using the operational data from 729 battery swapping stations in Shanghai, the spatiotemporal heterogeneity of rider demand is analyzed to validate the model’s effectiveness. Results reveal that daily swapping demand in core commercial areas is 3–10 times higher than in peripheral regions. The optimal scheduling network exhibits a ‘centralized radial’ structure, with nearly 50% of batteries dispatched from low-demand peripheral stations to high-demand central zones, significantly reducing transportation costs and resource redundancy. This study shows that the proposed model effectively mitigates battery supply demand mismatches and enhances scheduling efficiency. Future research may incorporate real-time traffic data to refine cost functions and introduce temporal factors to improve model adaptability. Full article
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24 pages, 9987 KiB  
Article
Ecological Zoning Based on Suitability Evaluation of Ecological Product Development from the Value-Risk-Cost-Demand Perspective
by Ming Gao, Pei Du, Xinxin Zhou, Zhenxia Liu, Wen Luo, Zhaoyuan Yu and Linwang Yuan
ISPRS Int. J. Geo-Inf. 2025, 14(3), 118; https://doi.org/10.3390/ijgi14030118 - 6 Mar 2025
Viewed by 787
Abstract
Current ecological value assessment models predominantly emphasize the potential value of ecological resources, neglecting the crucial aspect of value realization processes. Analyzing the value of ecological resources from the perspective of ecological products (EPs) is more instructive in realizing ecological values. The key [...] Read more.
Current ecological value assessment models predominantly emphasize the potential value of ecological resources, neglecting the crucial aspect of value realization processes. Analyzing the value of ecological resources from the perspective of ecological products (EPs) is more instructive in realizing ecological values. The key factors controlling the realization of ecological product value are potential value, ecological risk, development costs, and human demand. Previous research has rarely integrated these four factors within the ecological zoning framework. This study proposes a suitability evaluation and zoning framework for ecological product development based on the “value-risk-cost-demand” perspective. First, an evaluation index system for the potential value of ecological products was developed, dividing EPs into ecological agriculture (EA), ecological industry (EI), and ecological tourism (ET), and assessing them using 13 indicators. Ecological risks were modeled using multi-scale patch analysis (MSPA) and other models. Development costs were estimated using cost entropy. The impact of population dynamics on EP demand was quantified using population density, night-time light data, and average land GDP, along with stacked buffer analysis. Next, an improved TOPSIS method was applied to integrate these four dimensions, producing a comprehensive suitability assessment for EP development. Finally, EP zoning was determined by overlaying the comprehensive evaluation results. This framework was used to identify the dominant mode zones of EPs within the region of Jintan District, Jiangsu Province, China. The findings suggest that the integrated assessment model proposed in this study has produced more reasonable outcomes in terms of spatial layout, land use area, reduction of fragmentation and ecological risk. This conclusion is supported by spatial distribution comparisons, optimal area deviation analyses, landscape index calculations and multi-model driven future simulations. This model effectively resolves the spatial mismatch present in the traditional approach, which solely focuses on the potential value of EPs. This study can be applied to other regions with developed economies and rich ecological resources, providing an effective reference for the choice of paths to realize the value of EPs. Full article
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27 pages, 9960 KiB  
Article
Energy-Oriented Modeling of Hot Stamping Production Line: Analysis and Perspectives for Reduction
by Qiong Liu, Quan Zuo, Lei Li, Chen Yang, Jianwen Yan and Yuhang Xu
Energies 2024, 17(22), 5798; https://doi.org/10.3390/en17225798 - 20 Nov 2024
Viewed by 1194
Abstract
This research aims to develop a comprehensive mathematical model to analyze the energy usage of essential equipment in the hot stamping production line (HSPL) and identify opportunities for improving energy efficiency. This involves refining existing models and parameters related to energy consumption in [...] Read more.
This research aims to develop a comprehensive mathematical model to analyze the energy usage of essential equipment in the hot stamping production line (HSPL) and identify opportunities for improving energy efficiency. This involves refining existing models and parameters related to energy consumption in hot stamping to ensure precise energy usage monitoring throughout the HSPL. The main focus is on accurately calculating and validating the energy consumption efficiency of equipment within a product’s production cycle on the roller hearth furnace’s HSPL. The model has proven to be highly accurate in predicting energy consumption for various equipment. The average energy consumption of the HSPL in the case study is calculated as 0.597 kwh/kg, and the actual measurement is 0.625 kwh/kg. However, it revealed significant deviation in the cooling system, primarily due to the incorrect water pump head parameters utilization. As per the model’s calculations, most energy consumption is attributed to the furnace (77.51%), followed by the press (10.92%), chillers (6.86%), cooling systems (2.76%), and robots (1.95%). Actual measurements and model calculations highlight mismatches between equipment power ratings and actual demand, resulting in average operating power significantly lower than the rated power. In line with efforts to promote low-carbon manufacturing, practical approaches are being explored to conserve energy and enhance overall process efficiency by refining process parameters, reducing quenching duration, improving SPM on the production line, and adjusting load matching. Full article
(This article belongs to the Section K: State-of-the-Art Energy Related Technologies)
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10 pages, 979 KiB  
Article
The Construction of a Socialized Service Platform and System for “Internet + Agriculture” in China
by Run Tang, Qirui Liu and Ya Ou
Platforms 2024, 2(4), 211-220; https://doi.org/10.3390/platforms2040014 - 13 Nov 2024
Cited by 1 | Viewed by 1159
Abstract
The mismatch between supply and demand and inefficient supply in China’s agricultural product market is quite severe, making agricultural supply-side structural reform an important topic and task for rural economic work in China. The successful implementation of agricultural supply-side reform requires a comprehensive [...] Read more.
The mismatch between supply and demand and inefficient supply in China’s agricultural product market is quite severe, making agricultural supply-side structural reform an important topic and task for rural economic work in China. The successful implementation of agricultural supply-side reform requires a comprehensive agricultural social service platform and system to support it. However, the current agricultural social service platform system in China faces issues such as a lack of coordination among service entities and poor information communication, making it difficult to meet the demands of supply-side reform. To address this issue, under the new circumstances of supply-side reform, this paper proposes the idea of reorganizing the agricultural social service platform and system through industrial chain collaboration theory, and applying “internet +” for technological reengineering of the agricultural social service platform system. Based on this, a new agricultural social service platform system architecture is constructed, which includes service entities, service platforms, service content, and operational models. The research findings provide guidance for agricultural product producers, distributors, sellers, and related service entities along the agricultural industry chain on how to use “internet +” for collaborative decision-making. This approach is beneficial for addressing the supply-demand imbalance and low resource allocation efficiency in China’s agricultural product market, thereby advancing the structural reform of China’s agricultural supply side. Full article
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22 pages, 8213 KiB  
Article
Managing the Supply–Demand Mismatches and Potential Flows of Ecosystem Services in Jilin Province, China, from a Regional Integration Perspective
by Xinyue Jin, Jianguo Wang, Daping Liu, Shujie Li, Yi Zhang and Guojian Wang
Land 2024, 13(9), 1504; https://doi.org/10.3390/land13091504 - 16 Sep 2024
Cited by 1 | Viewed by 1139
Abstract
Regional integration strategically reorganizes spatially heterogeneous resources to maximize the overall benefits. Ecosystem services (ESs) are promising targets for regional integration due to their inherent heterogeneity and mobility, yet research in this area remains limited. This study quantifies crop production (CP), water yield [...] Read more.
Regional integration strategically reorganizes spatially heterogeneous resources to maximize the overall benefits. Ecosystem services (ESs) are promising targets for regional integration due to their inherent heterogeneity and mobility, yet research in this area remains limited. This study quantifies crop production (CP), water yield (WY), carbon storage (CS), and habitat quality (HQ) for the years 2000, 2010, and 2020 using the InVEST model and identifies four ES bundles through a K-means cluster analysis. A conceptual ecosystem service flow (ESF) network at the service cluster scale is constructed based on county-level ESF data. The results reveal the following: (1) there is an upward trend in the ES budget for all services from 2000 to 2020, coupled with spatial mismatches between supply and demand; (2) deficit nodes for CP and CS services are concentrated in densely populated districts, while deficits in WY and HQ services are mainly in western Jilin Province; (3) Bundles I and II act as “sources” of ES, Bundle IV serves as a “sink”, and Bundle III is the only cluster with a CP surplus, balancing CP services across the province. In addition, this study provides ecological perspectives for understanding regional integration by suggesting differentiated integrated management for different ecosystem bundles. Full article
(This article belongs to the Special Issue Deciphering Land-System Dynamics in China)
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17 pages, 7138 KiB  
Article
Metabolic Adaptation in Epilepsy: From Acute Response to Chronic Impairment
by Agustin Liotta, Stefan Loroch, Iwona Wallach, Kristoffer Klewe, Katrin Marcus and Nikolaus Berndt
Int. J. Mol. Sci. 2024, 25(17), 9640; https://doi.org/10.3390/ijms25179640 - 6 Sep 2024
Cited by 1 | Viewed by 1634
Abstract
Epilepsy is characterized by hypersynchronous neuronal discharges, which are associated with an increased cerebral metabolic rate of oxygen and ATP demand. Uncontrolled seizure activity (status epilepticus) results in mitochondrial exhaustion and ATP depletion, which potentially generate energy mismatch and neuronal loss. Many cells [...] Read more.
Epilepsy is characterized by hypersynchronous neuronal discharges, which are associated with an increased cerebral metabolic rate of oxygen and ATP demand. Uncontrolled seizure activity (status epilepticus) results in mitochondrial exhaustion and ATP depletion, which potentially generate energy mismatch and neuronal loss. Many cells can adapt to increased energy demand by increasing metabolic capacities. However, acute metabolic adaptation during epileptic activity and its relationship to chronic epilepsy remains poorly understood. We elicited seizure-like events (SLEs) in an in vitro model of status epilepticus for eight hours. Electrophysiological recording and tissue oxygen partial pressure recordings were performed. After eight hours of ongoing SLEs, we used proteomics-based kinetic modeling to evaluate changes in metabolic capacities. We compared our findings regarding acute metabolic adaptation to published proteomic and transcriptomic data from chronic epilepsy patients. Epileptic tissue acutely responded to uninterrupted SLEs by upregulating ATP production capacity. This was achieved by a coordinated increase in the abundance of proteins from the respiratory chain and oxidative phosphorylation system. In contrast, chronic epileptic tissue shows a 25–40% decrease in ATP production capacity. In summary, our study reveals that epilepsy leads to dynamic metabolic changes. Acute epileptic activity boosts ATP production, while chronic epilepsy reduces it significantly. Full article
(This article belongs to the Special Issue Molecular and Cellular Mechanisms of Epilepsy—3rd Edition)
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26 pages, 23573 KiB  
Article
Management on Transfer Pricing of Farmland Based on the Supply–Demand Mismatches for Multifunction: A Case Study from China
by Lijun Wu and Gaofeng Ren
Land 2024, 13(9), 1372; https://doi.org/10.3390/land13091372 - 27 Aug 2024
Viewed by 1115
Abstract
Realizing the multifunctional value of farmland is essential for regulating the pricing of farmland transfers and stabilizing the rural land market. However, in China, the mismatch between supply and demand leads to improper resource allocation, weakens the explicit value of farmland, and causes [...] Read more.
Realizing the multifunctional value of farmland is essential for regulating the pricing of farmland transfers and stabilizing the rural land market. However, in China, the mismatch between supply and demand leads to improper resource allocation, weakens the explicit value of farmland, and causes unreasonable transfer pricing mechanisms that threaten agricultural production and food security. This study develops an analytical framework to examine the relationship between farmland multifunction and transfer pricing from a supply–demand perspective. An evaluation index system is constructed, considering the physical, value, and material quantities. This study uses the matching index method and bivariate spatial autocorrelation to analyze the supply–demand match of farmland multifunction from 2014 to 2021 and its relationship with transfer prices. Additionally, management methods and strategies for dynamic zoning-based pricing under multifunctional matching trade-offs are proposed. The results show that: (1) There is significant heterogeneity in the supply and demand matching degree of different farmland functions in both space and time. The production and ecological functions of farmland are oversupplied, while the living functions are undersupplied. (2) Different spatial autocorrelation relationships exist between the degree of supply and demand matching of farmland functions and farmland transfer prices. Specifically, the supply and demand matching degrees of the production and living functions show a significant negative spatial correlation with farmland transfer prices. In contrast, the ecological function shows a significant positive spatial correlation with farmland transfer prices, which are continuously strengthening over time. (3) Based on the supply and demand matching situation of different farmland functions and the spatial autocorrelation of farmland transfer prices, nine types of regions are delineated for farmland functions. Among them, the surplus-coordinated development areas have the most cities, accounting for about 40%, with a wide distribution range. This study proposes zoning-based pricing instruments and management strategies. This research provides valuable insights for developing countries seeking to alleviate conflicts in multifunctional land use, enhance the sustainable protection of land resources, and improve land resource assessment frameworks. Full article
(This article belongs to the Special Issue Land Resource Assessment)
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20 pages, 15259 KiB  
Article
Supporting Efficiency Measurement and Tradeoff Optimization Methods of Ecosystem Services on Grain Production
by Baosheng Wang, Yiping Fang, Xueyuan Huang and Xinjun He
Land 2024, 13(7), 1040; https://doi.org/10.3390/land13071040 - 11 Jul 2024
Viewed by 1241
Abstract
Grain production (GP) is inherently dependent on ecosystem services (ESs). However, the increasing grain demand heightens the conflict between ESs and GP. This tension is further fueled by unstable natural, socio-economic, and political factors. To reconcile this issue and promote their mutual growth, [...] Read more.
Grain production (GP) is inherently dependent on ecosystem services (ESs). However, the increasing grain demand heightens the conflict between ESs and GP. This tension is further fueled by unstable natural, socio-economic, and political factors. To reconcile this issue and promote their mutual growth, quantifying the extent to which ESs support GP is essential. This study is designed to present a scientific method for measuring the impact of ESs on GP, thereby enhancing the objectivity and scientific rigor of strategies for ecological and food security. This study, by deconstructing the functional relationship between ESs and GP, employs the Super-SBM model to analyze the mathematical relationships between them, thereby achieving the quantification of the efficiency of ESs in supporting GP. The findings reveal the following key points: (1) the Super-SBM model offers a viable and scientifically robust approach for quantifying the supporting efficiency of ESs on GP; (2) the supporting efficiency of ESs for GP in 93.94% of the counties in the Hengduan Mountainous Region (HMR) is less than 1, indicating that both the efficiency and capacity of regional ESs to support GP are relatively low; (3) an obvious spatial mismatch in allocation is evident between the provision of ESs and the demands of GP in the HMR, which leading to regional supply–demand imbalance; (4) the slack relationships and quantity between ESs and grain output assessed by the Super-SBM model provide a scientific basis and optimization direction for crafting sustainable development strategies between ESs and GP. Supporting efficiency research, as an exploration of the relationship between ESs and GP in the quantitative dimension, represents a deepening of qualitative research, it serves to enhance the scientific basis for sustainable development decisions in the ecological environment and agricultural production, holding a certain degree of positive significance. Full article
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18 pages, 2232 KiB  
Article
The Reliability and Availability Analysis of a Single-Unit System under the Influence of Random Shocks and the Variation in Demand from Production with Erlang Distribution
by Zienab M. Hussien and Mohamed S. El-Sherbeny
Symmetry 2024, 16(7), 815; https://doi.org/10.3390/sym16070815 - 28 Jun 2024
Cited by 1 | Viewed by 922
Abstract
This study evaluates the reliability measures for a system consisting of a single unit that is subject to random shocks at random times with mismatches between demand and production. The system may sometimes be subject to random shocks leading to a system failure [...] Read more.
This study evaluates the reliability measures for a system consisting of a single unit that is subject to random shocks at random times with mismatches between demand and production. The system may sometimes be subject to random shocks leading to a system failure with probability p. The system may also fail completely for various reasons other than shocks. The unit is serviced by a technician if it is affected by a shock. However, the system may fail during operation for various other reasons, such as a programming error, human error, operational continuity and stress, and weather conditions. A single technician immediately repairs or maintains the failed unit. The system is in an operational state when there is demand or in an idle state when there is no demand. The distributions of all times in this system follow a negative exponential, while the time to repair follows a two-stage Erlang distribution. The expressions for the reliability metrics are obtained as functions of time using the Laplace transform and the supplementary variables technique. Sensitivity and relative sensitivity analyses were also performed for the system parameters. Finally, the efficiency of the system is illustrated using numerical examples. Full article
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