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Search Results (2,293)

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Keywords = physical environmental factors

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21 pages, 356 KB  
Article
Exploring the Interplay of Social, Economic, and Environmental Factors on Livelihood Sustainability in Quang Tri’s Coastal Forest Areas
by Ha Hong Bui, Thiet Phan Nguyen, Vich Hong Pham and Khanh Le Phi Ho
Sustainability 2025, 17(17), 7661; https://doi.org/10.3390/su17177661 (registering DOI) - 25 Aug 2025
Abstract
This study investigates the sustainable livelihoods of households in the coastal forest regions of Quang Tri Province, Vietnam, focusing on identifying the key factors that shape household resilience in the face of socio-economic and environmental challenges. Although the sustainable livelihoods approach is widely [...] Read more.
This study investigates the sustainable livelihoods of households in the coastal forest regions of Quang Tri Province, Vietnam, focusing on identifying the key factors that shape household resilience in the face of socio-economic and environmental challenges. Although the sustainable livelihoods approach is widely established in research, this study differentiates itself by applying a multivariate analysis to explore the relative impacts of various livelihood capitals—human, physical, financial, social, and environmental—specifically within the context of coastal forest ecosystems, a relatively under-researched area in Vietnam. The research identifies both factors affecting livelihood outcomes, emphasizing the role of community resources, seasonal fluctuations, and adaptation strategies. Additionally, the study highlights how environmental changes and natural resource constraints are more detrimental to livelihoods in these regions compared to other rural settings. Through these insights, this paper contributes to the growing body of literature by offering a nuanced understanding of how coastal forest communities can navigate the pressures of climate change, market volatility, and limited resources. The findings underscore the importance of enhancing adaptive capacity and crafting targeted policy interventions to support vulnerable households in the region. This study also highlights the limitations of existing research, emphasizing the need for future studies to integrate the complex interplay of environmental, social, and economic factors in coastal ecosystems. Full article
11 pages, 238 KB  
Perspective
The Interplay Between Environment and Drug Effects: Decoding the Ecocebo Phenomenon with Virtual Technologies
by Thomas Zandonai and Cristiano Chiamulera
Sensors 2025, 25(17), 5268; https://doi.org/10.3390/s25175268 - 24 Aug 2025
Abstract
In this perspective article, we introduce Ecocebo as a novel concept describing the modulatory effects of physical environments, whether natural or built, on drug effect. Positioned as a spatial component of the placebo effect, Ecocebo is grounded in evidence-based design principles and proposes [...] Read more.
In this perspective article, we introduce Ecocebo as a novel concept describing the modulatory effects of physical environments, whether natural or built, on drug effect. Positioned as a spatial component of the placebo effect, Ecocebo is grounded in evidence-based design principles and proposes that environmental features such as natural light, greenery, spatial geometry, and calming esthetics can significantly influence sensory, emotional, and cognitive processes. These environmental factors may enhance or modify pharmacological responses, especially for analgesics, anxiolytics, and antidepressants. We highlighted how exposure to restorative spaces can reduce pain perception, stress, and the need for medication, paralleling findings in placebo research where contextual and sensory cues influence brain regions linked to emotion and pain regulation. We propose virtual reality (VR) as the most suitable methodological tool to study Ecocebo in controlled and ecologically valid settings. VR allows for the precise manipulation of spatial features and real-time monitoring of physiological and psychological responses. We also propose integrating VR with neuromodulation techniques to investigate brain–environment–drug interactions. Finally, we addressed key methodological challenges such as defining control conditions and standardizing the measurement of presence. This perspective opens new directions for the integration of non-pharmacological and pharmacological interventions and personalized therapeutic environments to optimize clinical outcomes. Full article
14 pages, 256 KB  
Article
Towards Better Communication Accessibility for People Living with Aphasia: Identifying Barriers and Facilitators in Financial Institutions
by Sarah Bérubé-Lalancette, Monica Lavoie, Annie Légaré, Valérie Poulin, Marie-Ève Lamontagne, Joëlle Duchesne and Laura Monetta
Disabilities 2025, 5(3), 72; https://doi.org/10.3390/disabilities5030072 - 23 Aug 2025
Viewed by 78
Abstract
Approximately one-third of stroke survivors live with aphasia, an acquired communication disorder that significantly impacts their ability to understand, speak, read, or write. This condition often leads to social isolation and a reduced quality of life. Financial institutions, as essential community services, present [...] Read more.
Approximately one-third of stroke survivors live with aphasia, an acquired communication disorder that significantly impacts their ability to understand, speak, read, or write. This condition often leads to social isolation and a reduced quality of life. Financial institutions, as essential community services, present numerous communication barriers for people living with aphasia. This study aims to identify the barriers and facilitators influencing the communicative accessibility of financial institutions for people living with aphasia and to discuss solutions to optimize accessibility. A qualitative descriptive research design was employed, involving semi-structured interviews with people living with aphasia and questionnaires filled by employees from financial institutions. Data were analyzed using thematic analysis to identify key themes related to barriers and facilitators. People living with aphasia identified thirteen types of barriers and forty facilitators, related to physical environmental factors, conversational attitudes and service systems and policies. Financial institution employees highlighted the need for better training and awareness regarding aphasia. The study underscores the significant barriers people living with aphasia face in financial institutions and the potential facilitators that could enhance communicative accessibility. Implementing targeted training programs and standardizing accessibility policies are crucial steps towards improving service access for people living with aphasia. Full article
27 pages, 4358 KB  
Article
Study on the Performance of Copper(II) Sorption Using Natural and Fe(III)-Modified Natural Zeolite–Sorption Parameters Optimization and Mechanism Elucidation
by Marin Ugrina, Ivona Nuić and Jelena Milojković
Processes 2025, 13(9), 2672; https://doi.org/10.3390/pr13092672 - 22 Aug 2025
Viewed by 185
Abstract
This study evaluates and compares the sorption performance of natural zeolite (NZ) and Fe(III)-modified zeolite (FeZ) in removing Cu(II) ions from aqueous solutions, with the goal of assessing their potential for environmental remediation. NZ was modified with Fe(NO3)3, NaOH [...] Read more.
This study evaluates and compares the sorption performance of natural zeolite (NZ) and Fe(III)-modified zeolite (FeZ) in removing Cu(II) ions from aqueous solutions, with the goal of assessing their potential for environmental remediation. NZ was modified with Fe(NO3)3, NaOH and NaNO3 solutions to improve its sorption properties. The modification led to a slight decrease in crystallinity (XRD), increase in pore volume (BET), functional groups (FTIR) and negative surface charge (zeta potential), thereby improving the affinity of FeZ towards Cu(II). Batch sorption experiments were conducted to optimize key parameters including pH, solid/liquid ratio (S/L), contact time, and initial Cu(II) concentration. The pHo and S/L ratio were identified as key factors significantly influencing Cu(II) sorption on both zeolites, with a particularly pronounced effect observed for FeZ. The optimal conditions determined were pHo = 3–5 for NZ, pHo = 3 for FeZ, S/L = 10 g/L and a contact time of 600 min. Experimental results confirmed that FeZ has almost twice the sorption capacity for Cu(II) compared to NZ (0.271 mmol/g vs. 0.156 mmol/g), as further supported by elemental analysis, SEM-EDS and mapping analysis of saturated samples. The sorption of Cu(II) followed a mechanism of physical nature driven by ion exchange, dominated by intraparticle diffusion as the rate-controlling step. Leaching of copper-saturated zeolites according to the standard leaching method, DIN 38414 S4, demonstrated the ability of both zeolites to fully retain Cu(II) within their structure over a wide pH range, 4.01 ≤ pHo ≤ 10.06. These findings highlight the superior performance of FeZ and its potential as an effective material for the remediation of copper-contaminated environments. Full article
(This article belongs to the Section Environmental and Green Processes)
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21 pages, 15008 KB  
Article
The Impact of Built Environment on Urban Vitality—A Multi-Scale Geographically Weighted Regression Analysis in the Case of Shenyang, China
by Xu Lu, Shan Huang, Wuqi Xie and Yuhang Sun
Buildings 2025, 15(17), 2989; https://doi.org/10.3390/buildings15172989 - 22 Aug 2025
Viewed by 74
Abstract
Urban vitality acts as a key driver of sustainable urban development, while the built environment serves as its physical foundation. However, spatial heterogeneity in urban landscapes leads to imbalanced impacts of economic, social, and environmental factors on vitality. Therefore, it is essential to [...] Read more.
Urban vitality acts as a key driver of sustainable urban development, while the built environment serves as its physical foundation. However, spatial heterogeneity in urban landscapes leads to imbalanced impacts of economic, social, and environmental factors on vitality. Therefore, it is essential to investigate the underlying principles governing vitality impacts imposed by diverse components of the built environment at the spatial level. This study synthesized multi-source remote sensing data alongside geospatial datasets aiming to quantify vitality and built environment indicators across Shenyang, China. We applied Ordinary Least Squares (OLS) regression for collinearity diagnosis and Multi-scale Geographically Weighted Regression (MGWR) to model spatial heterogeneity impacts at the planning-unit level. The regression factor analysis yielded three primary conclusions: (1) Functional Mixture Degree, Bus Stop Density, and Subway Station Density demonstrated a statistically significant positive correlation with urban vitality. (2) FAR (Floor Area Ratio), Vegetation Coverage, Commercial Facility Density, and Road Density exhibited differentiated effects in core areas versus peripheral areas. (3) Public Facility Density and Bus Stop Density showed a negative correlation trend with vitality levels in Industrial Functional Zones. We propose a geospatial analysis framework that leverages remote sensing to decode spatially heterogeneous built environment–vitality linkages. This approach supports precision urban renewal planning by identifying location-specific interventions. Geospatial big data and MGWR offer replicable tools for analyzing urban sustainability. Future work should integrate real-time sensor data to track vitality dynamics. Full article
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14 pages, 1379 KB  
Article
Physical–Mechanical Properties of Innovative Biobased Particleboards for Application in External Building Façades
by Ramunas Tupciauskas, Andris Berzins, Martins Andzs, Rudolfs Berzins, Janis Rizikovs and Gunars Pavlovics
Forests 2025, 16(8), 1359; https://doi.org/10.3390/f16081359 - 21 Aug 2025
Viewed by 125
Abstract
Human activities undoubtedly increase greenhouse gases (GHG), negatively influencing global climate change. The building and construction sector uses at least 40% of the total energy consumption and produces the same percentage of GHG emissions. Therefore, the development of sustainable building materials is a [...] Read more.
Human activities undoubtedly increase greenhouse gases (GHG), negatively influencing global climate change. The building and construction sector uses at least 40% of the total energy consumption and produces the same percentage of GHG emissions. Therefore, the development of sustainable building materials is a crucial key factor for environmental protection. The study contributes to the development of bio-based façade materials using available raw biomass like wheat straw, grey alder, and softwood (a mix of spruce and pine), to promote reduced emissions of CO2. Two technologies were used to produce high-density particleboards based on (1) steam explosion treatment and (2) the addition of bio-based suberinic acids as a binder. In addition to the biomass species and board type, the influence of conventional and mold hot-pressing was investigated on produced board properties: density, thickness swelling, modules of rupture and elasticity in bending, and internal bonding. The obtained particleboards demonstrate significant differences in terms of the tested properties depending on all variable factors. The best performance, in terms of physical–mechanical properties, was achieved by the conventionally hot-pressed board of steam-exploded grey alder particles, being influenced by the highest density (1380 kg/m3). Mold hot-pressing in most cases resulted in decreased performance of obtained boards. Full article
(This article belongs to the Section Wood Science and Forest Products)
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11 pages, 260 KB  
Article
Participatory Development of Digital Innovations for Health Promotion Among Older Adults: Qualitative Insights on Individual, Contextual, and Technical Factors
by Katja A. Rießenberger, Karina Povse and Florian Fischer
Int. J. Environ. Res. Public Health 2025, 22(8), 1311; https://doi.org/10.3390/ijerph22081311 - 21 Aug 2025
Viewed by 166
Abstract
Location-based games offer innovative approaches for health promotion among older adults, but their effectiveness depends on understanding complex contextual factors beyond technological design. In our study, we aimed to adapt a location-based game in the form of a smartphone application which originally targeted [...] Read more.
Location-based games offer innovative approaches for health promotion among older adults, but their effectiveness depends on understanding complex contextual factors beyond technological design. In our study, we aimed to adapt a location-based game in the form of a smartphone application which originally targeted younger people. We employed ethnographic observations in a field test under real-world conditions for identifying the needs and preferences of older adults in this regard. Field notes of one co-creative workshop were analyzed using thematic analysis. Four key contextual factor categories emerged that significantly influenced user engagement: (1) temporal/spatial factors including weather conditions, topography, and traffic safety that impacted screen visibility and cognitive function; (2) virtual-physical orientation challenges requiring high cognitive load to transfer abstract digital maps to real environments; (3) individual factors such as technical competence, mobility levels, and prior accessibility experiences that shaped usage patterns; and (4) social dynamics that provided motivation and peer support while potentially creating exclusionary practices. Successful digital health innovations for older adults require a socio-technical systems approach that addresses environmental conditions, reduces cognitive transfer demands between virtual and physical navigation, leverages social elements while preventing exclusion, and accounts for heterogeneity among older adults as contextually interactive factors rather than merely individual differences. Full article
(This article belongs to the Special Issue Digital Innovations for Health Promotion)
16 pages, 690 KB  
Article
Upregulation of HOTTIP and Its Potential Role in Monitoring Exercise Adaptation
by Agnieszka Mołoń, Dominika Podgórska, Artur Płonka, Wojciech Bajorek, Wojciech Czarny, Paweł Król, Rafał Podgórski and Marek Cieśla
Int. J. Mol. Sci. 2025, 26(16), 8086; https://doi.org/10.3390/ijms26168086 - 21 Aug 2025
Viewed by 153
Abstract
Athletic performance is modulated by a complex interaction of physiological, environmental, and genetic factors, with regular exercise triggering molecular changes that influence gene expression and tissue adaptation. Despite growing knowledge, the underlying molecular mechanisms remain only partially understood, highlighting the need for precise [...] Read more.
Athletic performance is modulated by a complex interaction of physiological, environmental, and genetic factors, with regular exercise triggering molecular changes that influence gene expression and tissue adaptation. Despite growing knowledge, the underlying molecular mechanisms remain only partially understood, highlighting the need for precise biomarkers to monitor training-induced physiological adaptations. Long non-coding RNAs (lncRNAs) regulate cellular processes, including adaptation to physical exercise. Twelve healthy elite female volleyball players (mean age 27 ± 5.4 years) participated in the study. This study evaluated the expression of selected lncRNAs (SNHG4, SNHG5, PACERR, NEAT1, HIX003209, and HOTTIP) during a 10-week training program and evaluated their potential as biomarkers of training adaptation. Blood samples were collected before and after the training period. LncRNA expression was measured by quantitative polymerase chain reaction. HOTTIP exhibited an increase in expression after training (over sixfold change, p = 0.009, adjusted p = 0.024) and demonstrated high diagnostic accuracy (AUC = 0.917), which improved to 0.97 when combined with creatine kinase. Other lncRNAs showed no significant changes, although a correlation between HOTTIP and SNHG4 was noted. HOTTIP is markedly upregulated following chronic exercise and, especially when combined with creatine kinase, shows promise as a molecular biomarker for monitoring training adaptation in elite female volleyball players. Full article
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23 pages, 1403 KB  
Systematic Review
Perinatal and Childhood Risk Factors of Adverse Early Childhood Developmental Outcomes: A Systematic Review Using a Socioecological Model
by Kendalem Asmare Atalell, Gavin Pereira, Bereket Duko, Sylvester Dodzi Nyadanu and Gizachew A. Tessema
Children 2025, 12(8), 1096; https://doi.org/10.3390/children12081096 - 20 Aug 2025
Viewed by 164
Abstract
Background: Adverse early childhood developmental outcomes across physical, cognitive, language, communication, and socioemotional domains are major global health concerns. This systematic review aimed to synthesise perinatal and childhood risk factors using a socioecological model. Methods: We searched six databases for cohort, case–control, and [...] Read more.
Background: Adverse early childhood developmental outcomes across physical, cognitive, language, communication, and socioemotional domains are major global health concerns. This systematic review aimed to synthesise perinatal and childhood risk factors using a socioecological model. Methods: We searched six databases for cohort, case–control, and cross-sectional studies published between January 2000 and January 2024. Studies reporting risk factors for adverse developmental outcomes were included. Findings were organised across individual, interpersonal, community, and societal levels using a socioecological model. The protocol was registered in PROSPERO (CRD42023447352). Results: A total of 175 studies were included. Individual-level risk factors, including preterm birth, low birth weight, male sex, chronic illness, undernutrition, and excessive screen use, were associated with adverse developmental outcomes, while exclusive breastfeeding, reading books, and storytelling were protective factors. Interpersonal risks included maternal age, education, mental health, and pregnancy complications. Community and societal risks include environmental pollution, access to education, conflict, and healthcare access. Conclusions: Improving early childhood developmental outcomes may require intervention at multiple levels. Future studies may need to focus on the influence of culturally and linguistically diverse backgrounds and environmental exposures on early childhood developmental outcomes. Full article
(This article belongs to the Section Pediatric Mental Health)
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32 pages, 4521 KB  
Article
Research on Design of Underground Space for Refuge Based on Environmental Psychology and Virtual Reality
by Yufei Liu, Yukuan Ou-Yang, Jian Wang, Lei Wang, Bing Li and Zimo Chen
Sustainability 2025, 17(16), 7527; https://doi.org/10.3390/su17167527 - 20 Aug 2025
Viewed by 376
Abstract
Underground spaces hold significant potential for enhancing urban resilience against disasters, a key dimension of sustainable urban development. However, due to persistent associations of underground environments with negative psychological perceptions, these spaces—despite their superior protective advantages—are often overlooked as viable refuge options during [...] Read more.
Underground spaces hold significant potential for enhancing urban resilience against disasters, a key dimension of sustainable urban development. However, due to persistent associations of underground environments with negative psychological perceptions, these spaces—despite their superior protective advantages—are often overlooked as viable refuge options during emergencies. Guided by the theoretical framework of environmental psychology, this research focuses on underground parking garages in Hangzhou, China as its primary research object. The target participants are residents of Hangzhou aged 18–58 years (encompassing diverse occupations such as students, office workers, and service industry employees), who represent potential users of such spaces as refuges. To explore human behavioral patterns, psychological responses, and needs related to underground refuge spaces, we employed a two-phase methodology: first, a questionnaire survey to capture broader behavioral tendencies and subjective perceptions; complementing this, Virtual Reality (VR) experiments—a more immersive method—utilizing semantic analysis and the Likert scale to assess psychological indicators influenced by underground environments. The experimental data were analyzed via mean analysis, correlation analysis, and multiple linear regression analysis to identify the key environmental factors that influence psychological responses, as well as their optimal design parameters. These analyses reveal significant correlations between various environmental factors and psychological indicators. This research synthesizes individuals’ psychological tendencies in underground environments and proposes quantitative physical design guidelines to meet fundamental psychological needs. The findings provide theoretical and practical support for the design of underground space for refuge and the development of sustainable urban emergency shelter systems, thereby contributing to resilient and sustainable urban development. Full article
(This article belongs to the Section Sustainable Urban and Rural Development)
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58 pages, 7149 KB  
Review
Secure Communication in Drone Networks: A Comprehensive Survey of Lightweight Encryption and Key Management Techniques
by Sayani Sarkar, Sima Shafaei, Trishtanya S. Jones and Michael W. Totaro
Drones 2025, 9(8), 583; https://doi.org/10.3390/drones9080583 - 18 Aug 2025
Viewed by 412
Abstract
Deployment of Unmanned Aerial Vehicles (UAVs) continues to expand rapidly across a wide range of applications, including environmental monitoring, precision agriculture, and disaster response. Despite their increasing ubiquity, UAVs remain inherently vulnerable to security threats due to resource-constrained hardware, energy limitations, and reliance [...] Read more.
Deployment of Unmanned Aerial Vehicles (UAVs) continues to expand rapidly across a wide range of applications, including environmental monitoring, precision agriculture, and disaster response. Despite their increasing ubiquity, UAVs remain inherently vulnerable to security threats due to resource-constrained hardware, energy limitations, and reliance on open wireless communication channels. These factors render traditional cryptographic solutions impractical, thereby necessitating the development of lightweight, UAV-specific security mechanisms. This review article presents a comprehensive analysis of lightweight encryption techniques and key management strategies designed for energy-efficient and secure UAV communication. Special emphasis is placed on recent cryptographic advancements, including the adoption of the ASCON family of ciphers and the emergence of post-quantum algorithms that can secure UAV networks against future quantum threats. Key management techniques such as blockchain-based decentralized key exchange, Physical Unclonable Function (PUF)-based authentication, and hierarchical clustering schemes are evaluated for their performance and scalability. To ensure comprehensive protection, this review introduces a multilayer security framework addressing vulnerabilities from the physical to the application layer. Comparative analysis of lightweight cryptographic algorithms and multiple key distribution approaches is conducted based on energy consumption, latency, memory usage, and deployment feasibility in dynamic aerial environments. Unlike design- or implementation-focused studies, this work synthesizes existing literature across six interconnected security dimensions to provide an integrative foundation. Our review also identifies key research challenges, including secure and efficient rekeying during flight, resilience to cross-layer attacks, and the need for standardized frameworks supporting post-quantum cryptography in UAV swarms. By highlighting current advancements and research gaps, this study aims to guide future efforts in developing secure communication architectures tailored to the unique operational constraints of UAV networks. Full article
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62 pages, 6605 KB  
Review
Optimizing Mix Design for Alkali-Activated Concrete: A Comprehensive Review of Critical Selection Factors
by Ghasan Fahim Huseien, Mohammad Hajmohammadian Baghban, Iman Faridmehr and Kaijun Dong
CivilEng 2025, 6(3), 43; https://doi.org/10.3390/civileng6030043 - 18 Aug 2025
Viewed by 447
Abstract
In the construction sector, cement and concrete are among the most widely utilized manufactured materials, yet their environmental impact remains a significant concern. The concrete industry is a major contributor to carbon dioxide emissions, accounting for over 8% of global greenhouse gas emissions [...] Read more.
In the construction sector, cement and concrete are among the most widely utilized manufactured materials, yet their environmental impact remains a significant concern. The concrete industry is a major contributor to carbon dioxide emissions, accounting for over 8% of global greenhouse gas emissions annually. Several reports have estimated that between 1930 and 2013, a total of 4.5 gigatons of carbon was sequestered through the carbonation of cement-based materials. This process offset approximately 43% of the carbon dioxide (CO2) emissions resulting from cement production during the same period, excluding emissions related to fossil fuel consumption in the manufacturing process. It is well established that producing one ton of cement results in approximately 0.60–0.98 tons of CO2 emissions, coupled with substantial energy consumption. To mitigate these environmental effects, developing low-carbon or cement-free binders has become crucial. Alkali-activated binders (AABs), derived from industrial by-products or agricultural waste materials and activated with a low-molarity or one-part activator, are increasingly recommended as sustainable alternatives to reduce greenhouse gas emissions in the cement industry and minimize the consumption of natural resources. The production of alkali-activated concrete (AAC) involves several critical factors that significantly influence its mix design, fresh properties, and compressive strength (CS) performance. This study aims to provide a comprehensive review of the key factors affecting AAC’s mix design, workability, and CS characteristics. Firstly, the study discusses various methods employed for AAC mix design and the factors influencing these designs. Secondly, it examines the impact of binder type, source, chemical, mineralogical, and physical properties, as well as alkaline activator solutions, water content, and fillers on AAC’s workability, setting times, and strength development. Additionally, the study explores the correlation matrix and predictive performance models for fresh and strength properties. Lastly, the relationship between workability and CS is extensively analyzed. The review concludes by highlighting the existing challenges and prospects of AACs as sustainable construction materials to replace traditional cement and reduce carbon emissions. Full article
(This article belongs to the Section Construction and Material Engineering)
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33 pages, 1438 KB  
Review
Systems and Molecular Biology of Longevity and Preventive Medicine: Brain-Energy–Microbiome–Exposome Synergies in Blue Zones and the Cilento Case
by Silvana Mirella Aliberti, Mario Capunzo and Richard H. W. Funk
Int. J. Mol. Sci. 2025, 26(16), 7887; https://doi.org/10.3390/ijms26167887 - 15 Aug 2025
Viewed by 406
Abstract
Longevity and healthy aging result from the complex interaction of genetic, epigenetic, microbial, behavioral, and environmental factors. The central nervous system—particularly the cerebral cortex—and the autonomic nervous system (ANS) play key roles in integrating external and internal signals, shaping energy metabolism, immune tone, [...] Read more.
Longevity and healthy aging result from the complex interaction of genetic, epigenetic, microbial, behavioral, and environmental factors. The central nervous system—particularly the cerebral cortex—and the autonomic nervous system (ANS) play key roles in integrating external and internal signals, shaping energy metabolism, immune tone, and emotional regulation. This narrative review examines how the brain–ANS axis interacts with epigenetic regulation, telomere dynamics, the gut microbiome, and the exposome to influence biological aging and resilience. Relevant literature published between 2010 and 2025 was selected through comprehensive database searches (PubMed, Scopus, Google Scholar), with a focus on studies addressing the multisystemic determinants of aging. Emphasis is placed on lifestyle-related exposures, such as diet, physical activity, psychosocial support, and environmental quality, that modulate systemic physiology through neurovisceral pathways. Drawing on empirical findings from classical Blue Zones and recent observational research in the Cilento region of southern Italy, this review highlights how context-specific factors—such as clean air, mineral-rich water, Mediterranean dietary patterns, and strong social cohesion—may foster bioelectric, metabolic, and neuroimmune homeostasis. By integrating data from neuroscience, systems biology, and environmental epidemiology, the review proposes a comprehensive model for understanding healthy longevity and supports the development of personalized, context-sensitive strategies in geroscience and preventive medicine. Full article
(This article belongs to the Special Issue Molecular Endocrine Regulation in Health and Diseases)
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19 pages, 2607 KB  
Article
Sensitivity Analysis of the Temperature Field of Surrounding Rock in Cold-Region Tunnels Using a Fully Coupled Thermo-Hydrological Model
by Wentao Wu and Jiaqi Guo
Appl. Sci. 2025, 15(16), 9020; https://doi.org/10.3390/app15169020 - 15 Aug 2025
Viewed by 172
Abstract
The thermo-hydrological (TH) coupling model constitutes the foundational framework for investigating the temperature distribution of surrounding rock in cold region tunnels. In this study, a fully coupled TH model is proposed that takes into account multiple physical phenomena during the freezing process of [...] Read more.
The thermo-hydrological (TH) coupling model constitutes the foundational framework for investigating the temperature distribution of surrounding rock in cold region tunnels. In this study, a fully coupled TH model is proposed that takes into account multiple physical phenomena during the freezing process of surrounding rock. Firstly, the model was established based on thermodynamics, seepage theory, and ice–water phase change theory, which accounted for unfrozen water, latent heat of phase change, ice impedance, and convective heat transfer. The model was successfully verified by comparing its results to field data. Next, the sensitivity of surrounding rock temperature to environmental, thermodynamic, seepage, and coupling parameters in the fully coupled TH model was systematically studied using a numerical analysis method. The results show that the annual temperature amplitude and thermal conductivity represent the main factors affecting the surrounding rock temperature at a radial depth of 0 m, while the initial temperature and porosity are the key factors at a radial depth of 5 m. Permeability has the least influence on the surrounding rock temperature, but the temperature field will experience sudden changes if its value exceeds its value exceeds 1 × 10−12 m2. Finally, using the proposed numerical model, the thickness of insulation layer was simulated, and the degree of influence of the parameters on the thickness of insulation layer was analyzed. This study reveals that the annual temperature amplitude has the greatest influence on the calculation of insulation layer thickness, with its normalized sensitivity factor being approximately 50%. These findings not only expand the methodology for exploring the laws of TH coupling but also provide a theoretical foundation for improving the parameter calibration efficiency and calculation accuracy of the fully coupled TH model, and they have significant reference value. Full article
(This article belongs to the Section Applied Thermal Engineering)
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13 pages, 523 KB  
Article
Underground Inter-Nest Tunnels of Red Imported Fire Ants, Solenopsis invicta: Physical Features and Associations with Colony and Environmental Factors
by Meihong Ni, Juli Lu, Xinyi Yang, Yiran Zheng, Yuan Wang and Mingxing Jiang
Insects 2025, 16(8), 835; https://doi.org/10.3390/insects16080835 - 13 Aug 2025
Viewed by 431
Abstract
While foraging tunnels of the red imported fire ant, Solenopsis invicta, have been well studied, much less is known about the tunnels constructed between neighboring nests, despite their perceived importance in intra-colony exchange and collaboration. In this study, we investigated such tunnels [...] Read more.
While foraging tunnels of the red imported fire ant, Solenopsis invicta, have been well studied, much less is known about the tunnels constructed between neighboring nests, despite their perceived importance in intra-colony exchange and collaboration. In this study, we investigated such tunnels by excavating 80 pairs of nests (with distances of <1 m between nests) located in different types of habitats. For each pair of nests, we recorded the number of inter-nest tunnels and observed their shape, diameter, subsurface depth, and ant presence within them. Moreover, we analyzed the relationships between the probability of constructing inter-nest tunnels and several nest/habitat characteristics, including distance between nests, colony social form, nest size, soil type, and vegetation cover, as well as the relationships between tunnel numbers and these factors. The results show that the number of inter-nest tunnels ranges from one to 11. These tunnels open to the two nests at terminals, are elliptical in cross-section, <1.5 cm in diameter, and mostly at 1–3 cm (range 1–12 cm) subsurface depth. Among the 36 pairs of nests possessing tunnels, 31 pairs (86.1%) had worker or alate ants within their tunnels. Polygynous colonies are more likely (52.4%) to construct inter-nest tunnels than monogynous colonies (17.6%). Nest pairs that have a small nest, located in habitats with higher vegetation cover and loamy or sandy loam soil, tend to have inter-nest tunnels. We also showed that the capacity of constructing inter-nest tunnels falls in the regime similar to foraging tunnels. As nests were treated with chemicals, 33 nests were relocated and 47 new nests resulted within 2 weeks, but no definite tunnels were constructed between original nests and corresponding new nests. Our results highlight the significance of including such tunnels when analyzing intra-colony exchange, collaboration, and adaptive strategies in S. invicta. Uses of tunnels by fire ants during nest relocation, and the requirement of destroying them during control program implementation, were discussed. Full article
(This article belongs to the Special Issue Surveillance and Management of Invasive Insects)
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