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1,268 Results Found

  • Article
  • Open Access
10 Citations
14,347 Views
11 Pages

1 February 2018

In a semiconductor manufacturing process, defect cause analysis is a challenging task because the process includes consecutive fabrication phases involving numerous facilities. Recently, in accordance with the shrinking chip pitches, fabrication (FAB...

  • Article
  • Open Access
1,253 Views
15 Pages

12 February 2025

Ultrasonic imaging methods show significant advantages in detecting internal defects of composite crystalline materials. For polymer-bonded explosives (PBXs) with highly filled crystalline particles, the strong acoustic attenuation caused by their he...

  • Article
  • Open Access
12 Citations
2,064 Views
14 Pages

18 November 2022

For the problem of defect inversion in magnetic flux leakage technology, a fast, globally convergent particle swarm optimization algorithm based on the finite-element forward model is introduced as an inverse iterative algorithm in this paper. Two as...

  • Article
  • Open Access
5 Citations
3,336 Views
18 Pages

21 February 2024

As a critical foundational component, bearings find widespread application in various mechanical equipment. In order to achieve automated defect detection in the bearing-manufacturing process, a defect detection algorithm combining magnetic particle...

  • Article
  • Open Access
893 Views
14 Pages

29 July 2025

Understanding the hydration behavior of cementitious materials is crucial as it governs the setting, strength development and long-term durability of concrete. This study provides fundamental insights into these processes by investigating the early h...

  • Article
  • Open Access
1 Citations
1,530 Views
20 Pages

4 July 2024

A model framework for the prediction of defects in strip steel is proposed with the objective of enhancing the accuracy of defect detection. Initially, the data are balanced through the utilisation of the Improved Synthetic Minority Oversampling Tech...

  • Review
  • Open Access
12 Citations
5,165 Views
22 Pages

17 January 2022

The novel coronavirus SARS-CoV-2 has caused a pandemic resulting in millions of deaths worldwide. While multiple vaccines have been developed, insufficient vaccination combined with adaptive mutations create uncertainty for the future. Here, we discu...

  • Article
  • Open Access
3,118 Views
20 Pages

27 March 2023

The Al2O3 inclusions and mold flux particles are the initial causes of the sliver defects on the surface of automobile exposed panels. During the rolling process, the smashed Al2O3 inclusions or mold flux particles will hinder the growth of recrystal...

  • Review
  • Open Access
24 Citations
6,032 Views
15 Pages

12 December 2022

Defective interfering particles (DIPs) are particles containing defective viral genomes (DVGs) generated during viral replication. DIPs have been found in various RNA viruses, especially in influenza viruses. Evidence indicates that DIPs interfere wi...

  • Review
  • Open Access
7 Citations
2,846 Views
14 Pages

Defective RNA Particles of Plant Viruses—Origin, Structure and Role in Pathogenesis

  • Daria Budzyńska,
  • Mark P. Zwart and
  • Beata Hasiów-Jaroszewska

16 December 2022

The genomes of RNA viruses may be monopartite or multipartite, and sub-genomic particles such as defective RNAs (D RNAs) or satellite RNAs (satRNAs) can be associated with some of them. D RNAs are small, deletion mutants of a virus that have lost ess...

  • Article
  • Open Access
3 Citations
2,180 Views
18 Pages

16 May 2023

In order to improve the effectiveness of partial discharge detection in attached metal particle insulators, this paper proposes a partial discharge detection method for particle defects in insulators under high-frequency sinusoidal voltage excitation...

  • Article
  • Open Access
100 Citations
10,544 Views
29 Pages

2 October 2018

Two-dimensional (2D) materials are at the heart of many novel devices due to their unique and often superior properties. For simplicity, 2D materials are often assumed to exist in their text-book form, i.e., as an ideal solid with no imperfections. H...

  • Article
  • Open Access
2 Citations
1,901 Views
20 Pages

28 March 2025

RNA viruses pose a significant global public health burden due to their high mutation rates, zoonotic potential, and ability to evade immune responses. A common aspect of their replication is the generation of defective interfering particles (DIPs),...

  • Article
  • Open Access
3,227 Views
28 Pages

Exploring the Therapeutic Potential of Defective Interfering Particles in Reducing the Replication of SARS-CoV-2

  • Macauley Locke,
  • Dmitry Grebennikov,
  • Igor Sazonov,
  • Martín López-García,
  • Marina Loguinova,
  • Andreas Meyerhans,
  • Gennady Bocharov and
  • Carmen Molina-París

19 June 2024

SARS-CoV-2 still presents a global threat to human health due to the continued emergence of new strains and waning immunity among vaccinated populations. Therefore, it is still relevant to investigate potential therapeutics, such as therapeutic inter...

  • Review
  • Open Access
77 Citations
11,315 Views
17 Pages

13 July 2017

Modern vaccinology has increasingly focused on non-living vaccines, which are more stable than live-attenuated vaccines but often show limited immunogenicity. Immunostimulatory substances, known as adjuvants, are traditionally used to increase the ma...

  • Article
  • Open Access
9 Citations
2,439 Views
19 Pages

Formation Mechanism and Improvement of Magnetic Particle Inspection Defects in Cr5 Backup Roller Forged Ingot

  • Weifeng Zhang,
  • Guanbo Wang,
  • Yanling Zhang,
  • Guoguang Cheng and
  • Zhonghua Zhan

8 February 2022

Industrial tests and thermodynamic calculations were utilized to investigate the source and formation of magnetic particle inspection defects identified on the near-surface of the Cr5 back-up roll forged ingot, which was used in large cold rolling mi...

  • Article
  • Open Access
44 Citations
7,106 Views
20 Pages

12 June 2014

In this paper, efficient managing particle swarm optimization (EMPSO) for high dimension problem is proposed to estimate defect profile from magnetic flux leakage (MFL) signal. In the proposed EMPSO, in order to strengthen exchange of information amo...

  • Article
  • Open Access
14 Citations
4,680 Views
17 Pages

Broad-Spectrum Antiviral Activity of Influenza A Defective Interfering Particles against Respiratory Syncytial, Yellow Fever, and Zika Virus Replication In Vitro

  • Lars Pelz,
  • Elena Piagnani,
  • Patrick Marsall,
  • Nancy Wynserski,
  • Marc Dominique Hein,
  • Pavel Marichal-Gallardo,
  • Sascha Young Kupke and
  • Udo Reichl

4 September 2023

New broadly acting and readily available antiviral agents are needed to combat existing and emerging viruses. Defective interfering particles (DIPs) of influenza A virus (IAV) are regarded as promising options for the prevention and treatment of IAV...

  • Communication
  • Open Access
31 Citations
7,807 Views
14 Pages

Antiviral Activity of Influenza A Virus Defective Interfering Particles against SARS-CoV-2 Replication In Vitro through Stimulation of Innate Immunity

  • Ulfert Rand,
  • Sascha Young Kupke,
  • Hanna Shkarlet,
  • Marc Dominique Hein,
  • Tatjana Hirsch,
  • Pavel Marichal-Gallardo,
  • Luka Cicin-Sain,
  • Udo Reichl and
  • Dunja Bruder

11 July 2021

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing coronavirus disease 2019 (COVID-19) emerged in late 2019 and resulted in a devastating pandemic. Although the first approved vaccines were already administered by the end of 2020, w...

  • Review
  • Open Access
43 Citations
13,206 Views
26 Pages

14 February 2022

Virus-like particles resemble infectious virus particles in size, shape, and molecular composition; however, they fail to productively infect host cells. Historically, the presence of virus-like particles has been inferred from total particle counts...

  • Article
  • Open Access
10 Citations
4,777 Views
15 Pages

25 October 2017

This paper studies the defect detection problem of adhesive layer of thermal insulation materials. A novel detection method based on an improved particle swarm optimization (PSO) algorithm of Electrical Capacitance Tomography (ECT) is presented. Firs...

  • Article
  • Open Access
23 Citations
5,314 Views
14 Pages

26 January 2022

Fluorescent magnetic particle inspection (MPI) is a conventional non-destructive testing process for railway bearing rings that still needs to be completed manually. Due to the complexity of bearing ring surfaces in inspection, automatic detection fo...

  • Article
  • Open Access
4 Citations
2,246 Views
17 Pages

Simulation and Experimental Analysis of Surface Defects in Turning of TiCp/TC4 Composites

  • Haixiang Huan,
  • Chilei Zhu,
  • Biao Zhao,
  • Wenqiang Xu and
  • Ke Zhang

27 December 2022

Processing TiCp/TC4 composites has always been difficult due to the mismatch between the mechanical and thermal properties of the matrix and the reinforced particles, which results in a variety of machined surface defects. To expose the mechanism of...

  • Article
  • Open Access
3 Citations
4,326 Views
12 Pages

25 July 2017

Aimed to clarify the correlation characteristics between the internal partial discharge (PD) in negative direct current (DC) gas insulated system (GIS) and gas pressure initiated by two typical defects (i.e., free-metal particles and metal protrusion...

  • Article
  • Open Access
12 Citations
10,186 Views
22 Pages

27 July 2023

Chemical mechanical planarization (CMP) is a wafer-surface-polishing planarization technique based on a wet procedure that combines chemical and mechanical forces to fully flatten materials for semiconductors to be mounted on the wafer surface. The a...

  • Article
  • Open Access
236 Views
18 Pages

Investigation of Defect Propagation in 4H-SiC: From Substrate to Epitaxial Layers

  • Francesco Maria Fiorino,
  • Francesco Ruffino and
  • Alberto Catena

12 March 2026

Silicon carbide (SiC) is the leading wide bandgap semiconductor for high-power and high-temperature electronics, but the high defect density still limits device performance. This study investigates how inclusions, Basal Plane Dislocations (BPDs), and...

  • Article
  • Open Access
5 Citations
3,267 Views
16 Pages

Evaluation of Peri-Implantitis Bone Defect Healing: Comparing the Efficacy of Small-Particle Dentin and Bio-Oss in Bone Density Attenuation

  • Michał Łobacz,
  • Katarzyna Wieczorek,
  • Paulina Mertowska,
  • Sebastian Mertowski,
  • Marek Kos,
  • Ewelina Grywalska,
  • Grzegorz Hajduk and
  • Mansur Rahnama-Hezavah

8 August 2024

Introduction: Peri-implantitis is a serious complication in dental implantology that, if left untreated, may lead to implant loss and systemic diseases. Effective regeneration of bone defects resulting from peri-implantitis is crucial to maintaining...

  • Article
  • Open Access
6,435 Views
12 Pages

Efficient Co-Replication of Defective Novirhabdovirus

  • Ronan N. Rouxel,
  • Emilie Mérour,
  • Stéphane Biacchesi and
  • Michel Brémont

4 March 2016

We have generated defective Viral Hemorrhagic Septicemia Viruses (VHSV) which express either the green fluorescent protein (GFP) or a far-red fluorescent protein (mKate) by replacing the genes encoding the nucleoprotein N or the polymerase-associated...

  • Article
  • Open Access
2 Citations
984 Views
16 Pages

9 July 2025

During the manufacturing process of oil-immersed current transformers, metallic particles may become embedded in the insulation wrapping, and the resulting electric field distortion is one of the primary causes of failure. Historically, the shape of...

  • Feature Paper
  • Article
  • Open Access
2 Citations
2,030 Views
13 Pages

Magnetic Field Control of Liquid Crystal-Enabled Colloid Electrophoresis

  • Joel Torres-Andrés,
  • Guillermo Cassinello,
  • Francesc Sagués and
  • Jordi Ignés-Mullol

Microswimmers are key for unveiling new physical phenomena underlying their propulsion, especially when driven inside complex fluids. Liquid crystals are anisotropic complex fluids that feature long-range orientational order. The propulsion of non-ch...

  • Article
  • Open Access
22 Citations
4,679 Views
17 Pages

1 August 2017

The decomposition characteristics of a SF6 gas-insulated medium were used to diagnose the partial discharge (PD) severity in DC gas-insulated equipment (DC-GIE). First, the PD characteristics of the whole process were studied from the initial PD to t...

  • Article
  • Open Access
11 Citations
4,173 Views
13 Pages

Thixotropic Behavior in Defining Particle Packing Density of Highly Filled AP/HTPB-Based Propellant

  • Afni Restasari,
  • Luthfia Hajar Abdillah,
  • Retno Ardianingsih,
  • Hamonangan Rekso Diputro Sitompul,
  • Rika Suwana Budi,
  • Kendra Hartaya and
  • Heri Budi Wibowo

23 September 2021

An alarming, asymmetric flame in rocket combustion originates from a composite solid propellant (CSP) containing defects. The defects are the result of a composition that exceeds the maximum particle packing density. Based on the structure analysis o...

  • Article
  • Open Access
276 Citations
9,600 Views
14 Pages

Effects of Particle Size on the Structure and Photocatalytic Performance by Alkali-Treated TiO2

  • Danqi Li,
  • Hongchen Song,
  • Xia Meng,
  • Tingting Shen,
  • Jing Sun,
  • Wenjia Han and
  • Xikui Wang

18 March 2020

Particle size of nanomaterials has significant impact on their photocatalyst properties. In this paper, TiO2 nanoparticles with different crystalline sizes were prepared by adjusting the alkali-hydrothermal time (0–48 h). An annealing in N2 atm...

  • Article
  • Open Access
6 Citations
2,295 Views
15 Pages

Favipiravir Suppresses Zika Virus (ZIKV) through Activity as a Mutagen

  • Evelyn J. Franco,
  • Eleonora Cella,
  • Xun Tao,
  • Kaley C. Hanrahan,
  • Taj Azarian and
  • Ashley N. Brown

In a companion paper, we demonstrated that the nucleoside analogue favipiravir (FAV) suppressed Zika virus (ZIKV) replication in three human-derived cell lines—HeLa, SK-N-MC, and HUH-7. Our results revealed that FAV’s effect was most pron...

  • Article
  • Open Access
1 Citations
2,084 Views
17 Pages

A Water Environment-Based Simulated Method for Ultrasonic Testing of Slag Inclusion Weld Defects Based on Improved VMD

  • Jing Zhang,
  • Guocai Zhang,
  • Zijie Chen,
  • Hailin Zou,
  • Shuai Xue,
  • Jianjie Deng and
  • Jianqing Li

28 June 2024

The identification of slag inclusion defects in welds is of the utmost importance in guaranteeing the integrity, safety, and prolonged service life of welded structures. Most research focuses on different kinds of weld defects, but branch research on...

  • Article
  • Open Access
5 Citations
2,068 Views
13 Pages

7 February 2023

The creation of the natural ceiling rock of the coal seam is rife with fractures, holes, and other flaws. The angle of the defects has a significant influence on the mechanical characteristics and crack evolution of coal seam roof rock. Multi-scale n...

  • Article
  • Open Access
82 Citations
11,121 Views
22 Pages

Understanding the corrosion risk of a pipeline is vital for maintaining health, safety and the environment. This study implemented a data-driven machine learning approach that relied on Principal Component Analysis (PCA), Particle Swarm Optimization...

  • Article
  • Open Access
12 Citations
4,595 Views
19 Pages

11 December 2018

Skewness Decision Tree Support Vector Machine (SDTSVM) algorithm is widely known as a supervised learning model for multi-class classification problems. However, the classification accuracy of the SDTSVM algorithm depends on the perfect selection of...

  • Article
  • Open Access
6 Citations
9,406 Views
22 Pages

16 March 2011

Because of the perceived lack of systematic analysis in illumination system design processes and a lack of criteria for design methods in vision detection a method for the design of a task-oriented illumination system is proposed. After detecting the...

  • Article
  • Open Access
23 Citations
5,479 Views
19 Pages

Single-Cell Analysis Uncovers a Vast Diversity in Intracellular Viral Defective Interfering RNA Content Affecting the Large Cell-to-Cell Heterogeneity in Influenza A Virus Replication

  • Sascha Young Kupke,
  • Lam-Ha Ly,
  • Stefan Thomas Börno,
  • Alexander Ruff,
  • Bernd Timmermann,
  • Martin Vingron,
  • Stefan Haas and
  • Udo Reichl

7 January 2020

Virus replication displays a large cell-to-cell heterogeneity; yet, not all sources of this variability are known. Here, we study the effect of defective interfering (DI) particle (DIP) co-infection on cell-to-cell variability in influenza A virus (I...

  • Article
  • Open Access
3 Citations
3,741 Views
15 Pages

18 May 2020

The host-vector shuttle and the bottleneck in dengue transmission is a significant aspect with regard to the study of dengue outbreaks. As mosquitoes require 100–1000 times more virus to become infected than human, the transmission of dengue vi...

  • Article
  • Open Access
75 Citations
16,139 Views
17 Pages

Software Defect Prediction Analysis Using Machine Learning Techniques

  • Aimen Khalid,
  • Gran Badshah,
  • Nasir Ayub,
  • Muhammad Shiraz and
  • Mohamed Ghouse

21 March 2023

There is always a desire for defect-free software in order to maintain software quality for customer satisfaction and to save testing expenses. As a result, we examined various known ML techniques and optimized ML techniques on a freely available dat...

  • Article
  • Open Access
19 Citations
4,940 Views
15 Pages

Lassa Virus Vaccine Candidate ML29 Generates Truncated Viral RNAs Which Contribute to Interfering Activity and Attenuation

  • Dylan M. Johnson,
  • Beatrice Cubitt,
  • Tia L. Pfeffer,
  • Juan Carlos de la Torre and
  • Igor S. Lukashevich

30 January 2021

Defective interfering particles (DIPs) are naturally occurring products during virus replication in infected cells. DIPs contain defective viral genomes (DVGs) and interfere with replication and propagation of their corresponding standard viral genom...

  • Article
  • Open Access
10 Citations
2,910 Views
20 Pages

29 August 2022

In this paper, the effect of interlaminar properties and the type of delamination defects on the residual compression properties of carbon fiber laminates were experimentally investigated. A new method, which employed magnetic force to guide the arra...

  • Article
  • Open Access
16 Citations
5,589 Views
14 Pages

Development of a Singleplex Real-Time Reverse Transcriptase PCR Assay for Pan-Dengue Virus Detection and Quantification

  • Adisak Songjaeng,
  • Somchai Thiemmeca,
  • Dumrong Mairiang,
  • Nuntaya Punyadee,
  • Kessiri Kongmanas,
  • Prachya Hansuealueang,
  • Nattaya Tangthawornchaikul,
  • Thaneeya Duangchinda,
  • Juthathip Mongkolsapaya and
  • Panisadee Avirutnan
  • + 3 authors

10 June 2022

Dengue virus (DENV) infection is a significant global health problem. There are no specific therapeutics or widely available vaccines. Early diagnosis is critical for patient management. Viral RNA detection by multiplex RT-PCR using multiple pairs of...

  • Article
  • Open Access
2 Citations
2,589 Views
22 Pages

4 January 2023

Herpes simplex virus (HSV) and varicella zoster virus (VZV) rely on transport of virus particles in neuronal axons to spread from sites of viral latency in sensory ganglia to peripheral tissues then on to other hosts. This process of anterograde axon...

  • Article
  • Open Access
8 Citations
3,973 Views
17 Pages

6 October 2021

Nickel-based single-crystal superalloy turbine blades have been widely used in engines of aircrafts or power plants, but some defect grains are often found on the surface of the blade after full heat treatment or even after casting. Rhenium-rich part...

  • Article
  • Open Access
8 Citations
2,685 Views
14 Pages

This animal study was aimed to evaluate the efficacy of new bone formation and volume maintenance according to the particle type and the collagen membrane function for grafted octacalcium phosphate (OCP) in rabbit calvarial defects. The synthetic bon...

  • Article
  • Open Access
18 Citations
3,830 Views
16 Pages

12 March 2024

The cathodic protection provided by epoxy coating/epoxy zinc-rich coatings on defective areas under atmospheric and immersion conditions was studied via a Q235 wire beam electrode (WBE), scanning electron microscopy, X-ray diffraction, and surface mo...

  • Review
  • Open Access
24 Citations
4,035 Views
25 Pages

Critical-sized bone defects, or CSDs, are defined as bone defects that cannot be regenerated by themselves and require surgical intervention via employing specific biomaterials and a certain regenerative strategy. Although a variety of approaches can...

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