Search Results (3,797)

Hyperspectral remote sensing enables precise identification of alteration mineral through spectral–image integration and high-resolution capabilities. However, vegetation interference significantly hinders the extraction of alteration information in vegetated areas, thereby posing challenges to the reliable identification of alteration minerals. This study employs GF-5B satellite AHSI imagery acquired in the Huzhou region of Zhejiang Province, China, to address this challenge via a novel Zonal Adaptive Vegetation Suppression Technique (ZAVST). By constructing segmented statistical models that links reflectance characteristics across multiple spectral bands to NDVI values, ZAVST demonstrates an enhanced capability to mitigate vegetation obscuration effects on subsurface lithological features while substantially improving the identification of subtle spectral signatures characteristic of mineralization. Results reveal distinct spatial patterns: Fe-bearing alteration minerals (hematite, pyrite) align along NE-trending faults and volcanic basin margins; Al-OH alterations (montmorillonite, kaolinite) cluster near intrusive contacts; Mg-OH alterations (chlorite, epidote) occur at interfaces between carbonate sequences and concealed intrusions. Composite alteration anomalies exhibiting stacked mineral signatures (up to four distinct types) were identified across the region, demonstrating a strong spatial correlation with known mineralization centers. By integrating alteration zonation, structural lineaments, stratigraphy, geochemical anomalies, and orebody records, this study delineated four priority targets: Lijiaxiang Town, eastern Meixi Town, Miaoxi Town, and the central Moganshan Volcanic Basin. Full article

Background: Spinocerebellar ataxia type 2 (SCA2) is an inherited neurodegenerative disorder characterized by progressive cerebellar degeneration. One difficulty in treating this disease lies in identifying preclinical carriers: individuals who carry the pathogenic ATXN2 mutation but remain asymptomatic with respect to motor manifestations. Though magnetic resonance imaging (MRI) has proven valuable in supporting the diagnosis of ataxia, traditional univariate approaches using linear measurements have shown limited ability to capture the complex anatomical changes that occur across the disease spectrum, particularly during the preclinical phase. Methods: This study employed a comprehensive multivariate approach to improve the classification of individuals across the SCA2 spectrum. We developed a multinomial logistic regression model incorporating multiple linear measurements derived from magnetic resonance imaging to discriminate between healthy controls (n = 72), preclinical carriers (n = 17), and patients with manifest SCA2 (n = 61). To mitigate inherent class imbalance, particularly in the smaller preclinical subgroup, we implemented the Synthetic Minority Over-sampling Technique (SMOTE), generating a balanced dataset that enhances the model’s ability to discern the distinctive anatomical features. This was compared to the model applied to the unbalanced data. An improvement was observed when applying SMOTE. Results: The multivariate model demonstrated discriminatory performance, achieving an overall accuracy of 80.7%. The ability to identify healthy controls (AUC: 0.96), preclinical individuals (AUC: 0.75), and clinical individuals (AUC: 95%). This represents an advance over previous univariate approaches, which have had difficulty capturing the neurodegenerative changes characteristic of the preclinical stage. Conclusions: By integrating multiple neuroimaging biomarkers into a multivariable model, this study provides a tool for early identification of preclinical SCA2 carriers. The ability to accurately classify these individuals opens an opportunity for early therapeutic intervention before irreversible neurological deterioration occurs. This approach shows promise for optimizing clinical trial design and personalized care in SCA2. Full article

Synthetic aperture radar (SAR) ship detection faces three persistent challenges: coherent speckle noise that obscures target boundaries, heterogeneous background clutter in coastal and harbor scenes, and ship targets whose spatial extent varies by more than an order of magnitude within the same image. To address these issues jointly, this paper proposes MSA-DET, an improved SAR ship detection network built upon YOLOv11. In the backbone, a Multi-Scale Cross-axis Attention module (MSCAttention) runs horizontal and vertical axial attention branches in parallel across multiple receptive-field scales, sharpening feature representations for ship targets that vary widely in size and orientation. In the neck, the standard C3k2 block is redesigned as C3k2_SSA by embedding sparse self-attention, which selectively focuses on the most discriminative spatial tokens while suppressing speckle interference and reducing computational overhead. An Adaptive Spatial Feature Fusion detection head (ASFF) replaces fixed pyramid-level aggregation with learned per-pixel blending weights, resolving gradient conflicts across scales and improving localization consistency for both small and large ships. On the HRSID dataset, MSA-DET achieves an mAP@0.5:0.95 of 63.6% and mAP@0.5 of 88.1%, representing gains of 4.0% and 1.6% over the YOLOv11n baseline; on SSDD, it reaches 69.6% and 97.7%, surpassing the baseline by 7.2% and 2.1%, respectively. These results demonstrate that coordinated multi-stage redesign—rather than isolated module substitution—is an effective strategy for SAR-oriented ship detection. The accuracy gains are accompanied by a moderate increase in model size (8.9 M parameters versus 2.6 M for YOLOv11n) and computational cost (9.6 G FLOPs versus 6.3 G), a trade-off that is justified by the substantial improvement in detection quality. Full article

Background/Objectives: Spontaneous intracranial hypotension (SIH) is caused by spinal cerebrospinal fluid (CSF) leakage and is typically diagnosed by clinical presentation and characteristic MRI signs; however, objective tools for monitoring physiological changes and treatment response remain limited. Cine phase-contrast MRI (PC-MRI) enables noninvasive quantification of aqueductal CSF dynamics, yet reliable analysis is challenging since the cerebral aqueduct is extremely small and susceptible to low contrast, partial volume effects, and ROI-dependent measurement variability—particularly in SIH where CSF pulsatility is often reduced. Methods: We propose an end-to-end automated framework that integrates (1) a cascade localization–segmentation strategy, consisting of Tiny YOLOv4 detection followed by MultiResUNet segmentation on a YOLOv4-derived cropped ROI; (2) physiology-informed pulsatility-based segmentation (PUBS) to refine anatomical masks into functional flow ROIs; and (3) one-dimensional convolutional neural networks (1D-CNNs) to extract exploratory waveform morphology features from 32-phase cardiac-cycle velocity waveforms. The study includes 39 participants, yielding 59 cine PC-MRI examinations: 11 controls, 28 Pre-treatment SIH scans and 20 Post-treatment Recovery scans. Results: The cascade model significantly improves segmentation robustness compared with a full-image baseline, achieving higher Dice scores and markedly lower boundary errors across cohorts (e.g., Pre-treatment SIH HD95: 1.66 ± 0.74 px vs. 15.37 ± 44.98 px). PUBS refinement reduces quantification deviation from expert manual references in SIH (mean relative error: 7.4% to 5.6%) and improves diagnostic performance for multiple hemodynamic parameters (e.g., downward mean flow AUC: 0.747 to 0.792). For waveform morphology analysis, the end-to-end 1D-CNN classifier was evaluated using repeated-seed participant-level grouped LOOCV. The repeated-seed ensemble prediction showed modest out-of-sample discrimination between Normal controls and Pre-treatment SIH scans, with an AUC of 0.646, a bootstrap 95% confidence interval of 0.455–0.826, and a permutation-test p-value of 0.072. Separately, exploratory analysis of the final baseline-trained 1D-CNN latent space showed marked, apparent Normal-versus-SIH separability and an intermediate recovery distribution in PCA space, suggesting that aqueductal waveform morphology may encode SIH-related physiological information. Conclusions: These findings suggest that SIH-related information may be reflected not only in flow magnitude but also in aqueductal CSF waveform morphology. However, the modest and statistically non-significant out-of-sample performance of the end-to-end 1D-CNN classifier indicates that morphology-based AI features should currently be regarded as exploratory biomarker candidates rather than validated stand-alone diagnostic tools. Larger independent cohorts are required to confirm their reproducibility, physiological meaning, and clinical utility. Full article

Immunohistochemistry (IHC) is a widely used method for detecting specific proteins in tissue samples, helping diagnose diseases such as cancer. Traditional analysis methods rely heavily on human interpretation, which can lead to inconsistencies. In this study, we propose DeepFlare, a weakly supervised deep learning framework for cross-modality translation and segmentation of immunofluorescence and immunohistochemistry images. The proposed method utilizes multiplex immunofluorescence (mpIF) and co-registered IHC images, combined with preprocessing techniques such as affine transformation, stain normalization, noise reduction, and artifact removal. Multiple imaging channels, including hematoxylin, DAPI, Lap2, and nuclear envelope signals, are leveraged to generate segmentation masks using a U-Net++ architecture. The final segmentation mask is obtained through weighted fusion of modality-specific outputs. A generative adversarial network (GAN) is employed to measure translation fidelity between generated and real images. Weakly supervised learning techniques, including image-level supervision and consistency constraints, are applied to enhance performance under limited annotation scenarios. Pretrained pathology foundation encoders such as UNI and Virchow are integrated to extract multi-scale morphological and contextual features. Explainable AI techniques are incorporated to highlight critical regions and refine model attention. Experimental results demonstrate strong performance, achieving an SSIM of 0.7077 for image translation and a Dice score of 0.7424 for segmentation. The integration of the UNI encoder provides marginal improvement over the baseline (0.72 Dice score), indicating limited domain adaptation without fine-tuning on the dataset of 1264 training samples. Full article

Intracranial hemorrhage (ICH) is a life-threatening neurological condition that requires rapid and accurate diagnosis to reduce mortality and improve patient health. Computed tomography (CT) imaging is widely used for ICH detection. However, manual interpretation can be time-consuming and prone to errors, particularly in high-volume clinical settings. Recent studies have demonstrated the effectiveness of deep learning techniques in automating medical image analysis and improving diagnostic accuracy. In this study, we propose a novel deep learning model, MGiT-X, for the automated detection of intracranial hemorrhage using head CT images. The MGiT-X model is a hybrid deep learning architecture that uses dual scale Swin Transformer modules to extract features at multiple scales, capturing local and global contextual information on CT images. It has a Gradient Fusion mechanism to enhance feature representation by combining complementary features to distinguish between hemorrhagic and healthy tissue. In addition, to further improve feature representation, the use of Jensen–Shannon divergence is used to provide better mutual alignment and consistency between the distribution of features. An adaptive weight strategy is also employed to provide refinement to the importance of features for classification. MGiT-X is evaluated on two publicly available datasets including the Head CT Hemorrhage dataset and the Brain CT Hemorrhage dataset. The proposed approach leverages advanced feature extraction and classification capabilities to distinguish between hemorrhage and healthy cases effectively. Experimental results demonstrate that the proposed MGiT-X achieves high performance across both datasets. On Dataset 1, the model attains an overall accuracy of 95.87% and a Kappa score of 91.80%, while on Dataset 2, it achieves an improved accuracy of 99.12% with a Kappa score of 98.20%. Class-wise evaluation further shows strong performance, with F1-scores exceeding 95% for both hemorrhage and healthy classes across datasets. Full article

Target tracking for Unmanned Aerial Vehicles (UAVs) can be significantly impacted by environmental factors such as lighting variations, background clutter, and target occlusion. To address these challenges, we developed a target tracking method that integrates both frequency-domain and spatial perception capabilities in UAV vision (FSTrack). Specifically: (1) we utilized the Swin Transformer as the core network to extract features from both the template and search images; (2) we introduced a Transformer-based module to enhance both frequency and spatial information, improving tracking accuracy under varying illumination conditions; (3) we designed a spatio-temporal feature fusion module with multiple multi-head self-attention mechanisms to precisely model the tracking state, thus increasing reliability in cluttered and occluded environments; and (4) we created a hybrid loss function to boost accuracy in both classification and regression tasks. Our experimental results on the UAV123, DTB70, and UAVDT datasets show that our approach not only surpasses current state-of-the-art methods in success rates and precision but also operates more swiftly. Full article

Most remote sensing extraction studies utilizing vegetation indices typically classify and extract land cover features based on the phenological characteristics of the study area or rely on a single vegetation index. When attempting to extract multiple land cover types simultaneously, classification accuracy often declines significantly because a single vegetation index is unsuitable for all features. While some recent studies employ deep learning and neural networks for classification and extraction, their complex mechanisms and “black-box effect” hinder clear explanations for accuracy outcomes. In response to the issues outlined above, this paper proposes a simpler and more intuitive method for the hierarchical extraction of typical land cover features. This approach analyzes the difficulty of separating these features based on spectral reflectance data to determine the following extraction order: first water bodies, followed by reed, then Suaeda salsa, and finally tidal flat. Furthermore, by selecting appropriate parameters and substituting vegetation indices for bands that perform better, high extraction accuracy is achieved. The classification and interpretation results were validated using a combination of field survey data and Google imagery, together with a validation sample. Accuracy assessments using overall accuracy and Kappa coefficient demonstrate the following optimal results for the hierarchical approach: NDWI for water, S2REP for reeds, and MSAVI for Suaeda salsa. Overall accuracy reached 98.5% with a Kappa coefficient of 0.9796, validating the effectiveness of this spectral-feature-based hierarchical extraction method using diverse vegetation indices. Using a hierarchical extraction approach to classify typical land cover features in the study area from 2020 to 2025, accuracy rates exceeded 98% in all cases. Based on these classification results, the INVEST model was employed to simulate carbon stock trends in the Liaohe Estuary region over the past five years. The study found that, although factors such as tides and the date of image acquisition had a certain impact on the study area compared with the problems caused by historical development, the ecological environment in the study area is gradually stabilizing at the present stage. Full article

All-in-one weather-degraded image restoration aims to restore clean images from diverse weather-degraded observations (such as rain, haze, and snow) using a unified model. However, this topic remains challenging due to its ill-posed nature and the scarcity of large-scale paired training data. This article develops a novel semi-supervised learning framework, termed Semi-Supervised Degradation-Aware Learning (S²DAL), to adjust the feature space to align with the unified parameter space for all-in-one adverse weather removal. Specifically, the proposed S²DAL consists of two backbone networks: a Degradation-guided Histogram Transformer (DHformer) for weather-degraded image restoration and a Degradation-guided Convolutional Neural Network (DCNN) for degradation generation. A key component, the Degradation-guided Histogram Transformer (DHT) block, is designed to effectively capture intrinsic image features while suppressing diverse degradation interference through channel shuffling modulation, dynamic-range histogram self-attention, and dual-scale gated feed forward. Furthermore, a Monte Carlo-based Expectation-Maximization (EM) algorithm is introduced to jointly optimize latent variables and network parameters under both labeled and unlabeled data. Extensive quantitative and qualitative results on synthetic and real-world datasets consistently demonstrate that the proposed S²DAL achieves superior restoration performance compared to multiple state-of-the-art fully supervised and semi-supervised approaches. Full article

The introduction of noise during image acquisition and transmission is inevitable, leading to a significant reduction in the accuracy of image processing tasks, such as target classification, localization, and recognition. To address this issue, this paper proposes a novel robustness-oriented pooling module called Gaussian adaptive pooling. Drawing on the principles of Gaussian filters, the method introduces a Gaussian weight for feature values in the pooling operation, thus integrating filtering and pooling in a novel manner. This approach is both lightweight and versatile, requiring no additional learnable parameters, and enables seamless integration into neural network architectures with pooling layers. Rigorous mathematical derivations and simulation experiments show that our proposed Gaussian adaptive pooling method surpasses conventional methods (average-pooling and max-pooling) in noise handling. Furthermore, its robustness is comparable to traditional pooling methods in addressing challenges such as rotations, scalings, and translations. Extensive evaluations across multiple computer vision tasks—including image classification (CIFAR-10/100), object detection (MS COCO and RTTS), and semantic segmentation (CamVid)—confirm its effectiveness. Specifically, under varying levels of noise and degraded conditions, Gaussian adaptive pooling achieves significant improvements in standard performance metrics compared to conventional pooling methods. For instance, it delivers notable quantitative gains across different tasks including up to a 12.67% increase in mean intersection over union on the CamVid dataset for semantic segmentation and a 1.1% mAP50 enhancement on the real-world RTTS dataset for object detection. Full article

The fractal natural microstructure of shale reservoirs significantly influences hydraulic fracture propagation and reservoir stimulation. However, there is a lack of quantitative mathematical descriptions for the coupled regulation of micropores, natural fractures, and injection rates. This study develops a mathematical evaluation method for hydraulic fracture evolution in complex microstructured reservoirs using digital core technology, fractal geometry and a hydraulic–mechanical–damage coupling algorithm. High-resolution SEM images were used to reconstruct the microscopic fractal features. Integrated digital image processing and fractal analysis, along with geometric indices such as fractal dimension, fracture coverage, and stimulated area, and statistical measures including directional entropy, variance, and the Pearson correlation coefficient, were employed to systematically quantify fracture network evolution and complexity under different injection rates. Results show that fracture morphology, spatial complexity, and mineral damage mechanisms are jointly controlled by microstructure and injection rate. In particular, the directional distribution of pores and natural fractures is found to exert a dominant control on the propagation paths and branching behavior of hydraulic fractures, revealing a strong coupling between microstructural anisotropy and fracture directionality. Increased injection rates enhance fracture complexity and stimulation range, with varying effects from different microstructures. At low rates, fracture propagation is mainly determined by the initial microstructure, whereas at high rates, fractures tend to develop multiple pathways. Natural fracture structures contribute more to fracture complexity at high rates. The proposed comprehensive fracturability index (FI)-based fracturability evaluation model provides a systematic, quantitative approach to optimizing fracturing processes. Full article

Coal surface morphology plays a pivotal role in advanced coal processing operations, encompassing comminution, beneficiation, flotation kinetics, and intelligent process optimization. However, conventional characterization approaches are inherently labor-intensive and susceptible to inter-operator subjectivity, hindering their integration into autonomous industrial monitoring systems. To surmount these challenges, this study proposes an explainable morphology-aware coal surface characterization framework that synergizes unsupervised pseudo-label generation, targeted data augmentation, and explainable artificial intelligence. Initially, a high-dimensional feature set comprising grayscale intensity statistics, entropy, edge density, and Gray-Level Co-occurrence Matrix descriptors was extracted from 454 coal surface images. Subsequently, Principal Component Analysis and K-means clustering were implemented to identify intrinsic morphology-driven structural patterns, generating robust pseudo-labels without manual annotation. These pseudo-classes were utilized to train and benchmark multiple transfer learning architectures, including EfficientNetB0, VGG16, and MobileNetV3. Experimental results demonstrated that MobileNetV3 achieved superior classification efficacy under a strict leakage-safe evaluation configuration, exceeding 90% across key performance metrics while offering significantly lower computational complexity—ideal for edge-computing deployment. Furthermore, Grad-CAM-based interpretability analysis validated that the models focused on physically significant morphological features, such as fracture boundaries and heterogeneous texture transitions. These findings indicate that the proposed framework provides a robust, computationally efficient, and interpretable decision-support tool for smart beneficiation and intelligent industrial coal processing environments. Full article

Background and Clinical Significance: Tumefactive Multiple Sclerosis (TMS) represents a rare and diagnostically challenging form of demyelinating disease characterized by large space-occupying lesions that can closely mimic intracranial neoplasms, abscesses, and other inflammatory or vascular conditions. Case Presentation: The case highlights the overlapping radiologic features that frequently lead to diagnostic uncertainty and underscores the importance of careful interpretation of multimodal imaging and ancillary studies. Overall a comprehensive multidisciplinary evaluation is essential to reduce the risk of misdiagnosis and avoid unnecessary invasive interventions. Conclusions: This review summarizes current evidence regarding the diagnostic approach, imaging characteristics, and therapeutic strategies for tumefactive demyelinating lesions. Additionally, we present a clinical case that illustrates the diagnostic complexity of this entity, in which neuroimaging findings and cerebrospinal fluid analysis supported a demyelinating rather than neoplastic process. Full article

Deep learning-based automatic target recognition (ATR) for synthetic aperture radar (SAR) imagery requires large quantities of high-quality annotated data, yet real SAR samples are costly and difficult to obtain. Existing generative adversarial network (GAN)-based SAR generation methods often suffer from limited authenticity and insufficient diversity. To address these issues, we propose CA-DDPM, a conditionally embedded attention-aided denoising diffusion probabilistic model (DDPM) for high-quality multi-category SAR image generation. CA-DDPM employs a unified conditional embedding that fuses time-step and category information, injected into a U-Net backbone through a feature-wise linear modulation (FiLM)-based mechanism to achieve step-aware and class-aware denoising. Attention blocks are further incorporated to enhance the modeling of structural dependencies and fine scattering details. To evaluate generation quality, we develop a three-dimensional assessment framework that jointly examines authenticity, diversity, and utility in ATR. Authenticity is quantified using local and global similarity metrics under a unified Hungarian-matched statistical procedure, together with an SAR-adapted Fréchet inception distance (SAR-FID). Diversity is assessed through inter-category feature clustering, an SAR Inception Score (SAR-IS), and a newly proposed intra-category grayscale histogram-based metric. Utility is evaluated by hybrid training experiments across multiple ATR models. Experiments on the Moving and Stationary Target Acquisition and Recognition (MSTAR) dataset demonstrate that CA-DDPM produces more realistic and diverse SAR images than representative GAN- and DDPM-based baselines, and it effectively improves downstream ATR performance through data augmentation. Full article

Multimodal image fusion is a promising technology designed to fuse information from different medical sensors, which offer structured insights for disease diagnosis and treatment. However, existing 2D-centric fusion methods fail to capture 3D spatial continuity, and conventional wavelet-based approaches lack adaptability to diverse lesion regions and suffer from background artifacts. To address this issue, we propose a 3D multiscale wavelet convolutional neural network for multimodal medical image fusion. Specifically, a 3D Discrete Wavelet Transformation (3D DWT) is introduced to decompose input volumes into multi-frequency bands, isolating anatomical structures and lesion details while reducing 3D spatial redundancy. We embed hierarchical multiple frequency band into a Global and Local Feature Calibration (GLFC) module to adaptively enhance single-modal features by fusing global contextual information and local details. Furthermore, a pyramid group-wise multiscale feature interaction is proposed for capturing complementary features across different spatial scales. Finally, a voxel-wise weighted averaging strategy reconstructs the fused image by adaptively assigning contributions to each modality at every spatial position, effectively eliminating artifacts and improving the visual fidelity of the result. Extensive experiments on the BraTS2020 and Hecktor datasets demonstrate that our proposed method outperforms state-of-the-art (SOTA) fusion methods in both subjective visual quality and objective metrics. Moreover, downstream segmentation validation confirms that fused images from our method significantly improve tumor segmentation accuracy. The source code and pre-trained models will be publicly available. Full article