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Search Results (369)

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Keywords = multimodal health data

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28 pages, 7980 KB  
Article
Smart Predictive Maintenance: A TCN-Based System for Early Fault Detection in Industrial Machinery
by Abuzar Khan, Ahmad Junaid, Muhammad Farooq Siddique, Abid Iqbal, Husam S. Samkari, Mohammed F. Allehyani and Ghassan Husnain
Machines 2026, 14(2), 164; https://doi.org/10.3390/machines14020164 (registering DOI) - 1 Feb 2026
Abstract
Modern factories still struggle with unexpected machine failures because traditional maintenance systems depend on fixed rules and threshold-based alerts. These older approaches often overlook subtle or complex patterns in multimodal sensor data, causing them to miss early signs of wear and leading to [...] Read more.
Modern factories still struggle with unexpected machine failures because traditional maintenance systems depend on fixed rules and threshold-based alerts. These older approaches often overlook subtle or complex patterns in multimodal sensor data, causing them to miss early signs of wear and leading to late or incorrect maintenance decisions. As a result, production can slow down, costs increase and equipment reliability suffers. To address this challenge, this study introduces a smart and interpretable fault diagnosis and predictive maintenance framework designed to detect wear, degradation and potential failures before they disrupt operations. The proposed framework integrates multiscale feature extraction, multimodal sensor fusion and cross-sensor correlation analysis with advanced temporal modeling using a Temporal Convolutional Network (TCN). By jointly performing tool-health classification and Remaining Useful Life (RUL) estimation, the framework provides a comprehensive assessment of machine condition. When evaluated on the NASA Ames milling dataset, the model achieved an overall accuracy of 86%, correctly classifying healthy and failed tools in more than 88% of cases and worn tools in over 75%, demonstrating consistent performance across different stages of tool wear. Explainable artificial intelligence (XAI) techniques, including attention-based visualizations and SHAP-based feature attribution, reveal that electrical and vibration signals are the most influential early indicators of tool degradation. The proposed framework exhibits low computational latency and minimal memory requirements, making it suitable for real-time fault diagnosis and deployment on industrial edge devices. Overall, the framework balances predictive accuracy, interpretability and practical applicability, enabling proactive and reliable maintenance decisions that enhance machine uptime and support efficient smart manufacturing operations. Full article
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21 pages, 484 KB  
Review
Artificial Intelligence in Neonatal Respiratory Care: Current Applications and Future Directions
by Aikaterini Nikolaou, Maria Baltogianni, Niki Dermitzaki, Nikitas Chatzigiannis, Dimitra Savidou, Sevastianos Geitonas, Lida-Eleni Giaprou and Vasileios Giapros
Appl. Sci. 2026, 16(3), 1339; https://doi.org/10.3390/app16031339 - 28 Jan 2026
Viewed by 104
Abstract
Respiratory disorders remain a major cause of morbidity and mortality in neonatal intensive care units, particularly among preterm infants. Advances in physiological monitoring, medical imaging, and electronic health records have enabled the growing application of artificial intelligence in neonatal respiratory care. This narrative [...] Read more.
Respiratory disorders remain a major cause of morbidity and mortality in neonatal intensive care units, particularly among preterm infants. Advances in physiological monitoring, medical imaging, and electronic health records have enabled the growing application of artificial intelligence in neonatal respiratory care. This narrative review summarizes current applications and emerging directions of artificial intelligence in the diagnosis, monitoring, and management of neonatal respiratory disorders. Machine learning and deep learning approaches have demonstrated promising performance in respiratory distress syndrome, bronchopulmonary dysplasia, apnea of prematurity, ventilatory management, and severe respiratory complications. By integrating multimodal clinical, physiological, and imaging data, these methods support earlier detection of respiratory deterioration and improved clinical decision-making. However, challenges related to data quality, generalizability, interpretability, and limited prospective validation continue to constrain widespread clinical implementation, highlighting the need for careful integration into neonatal care workflows. Full article
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27 pages, 4885 KB  
Article
AI–Driven Multimodal Sensing for Early Detection of Health Disorders in Dairy Cows
by Agne Paulauskaite-Taraseviciene, Arnas Nakrosis, Judita Zymantiene, Vytautas Jurenas, Joris Vezys, Antanas Sederevicius, Romas Gruzauskas, Vaidas Oberauskas, Renata Japertiene, Algimantas Bubulis, Laura Kizauskiene, Ignas Silinskas, Juozas Zemaitis and Vytautas Ostasevicius
Animals 2026, 16(3), 411; https://doi.org/10.3390/ani16030411 - 28 Jan 2026
Viewed by 190
Abstract
Digital technologies that continuously quantify animal behavior, physiology, and production offer significant potential for the early identification of health and welfare disorders of dairy cows. In this study, a multimodal artificial intelligence (AI) framework is proposed for real-time health monitoring of dairy cows [...] Read more.
Digital technologies that continuously quantify animal behavior, physiology, and production offer significant potential for the early identification of health and welfare disorders of dairy cows. In this study, a multimodal artificial intelligence (AI) framework is proposed for real-time health monitoring of dairy cows through the integration of physiological, behavioral, production, and thermal imaging data, targeting veterinarian-confirmed udder, leg, and hoof infections. Predictions are generated at the cow-day level by aggregating multimodal measurements collected during daily milking events. The dataset comprised 88 lactating cows, including veterinarian-confirmed udder, leg, and hoof infections grouped under a single ‘sick’ label. To prevent information leakage, model evaluation was performed using a cow-level data split, ensuring that data from the same animal did not appear in both training and testing sets. The system is designed to detect early deviations from normal health trajectories prior to the appearance of overt clinical symptoms. All measurements, with the exception of the intra-ruminal bolus sensor, were obtained non-invasively within a commercial dairy farm equipped with automated milking and monitoring infrastructure. A key novelty of this work is the simultaneous integration of data from three independent sources: an automated milking system, a thermal imaging camera, and an intra-ruminal bolus sensor. A hybrid deep learning architecture is introduced that combines the core components of established models, including U-Net, O-Net, and ResNet, to exploit their complementary strengths for the analysis of dairy cow health states. The proposed multimodal approach achieved an overall accuracy of 91.62% and an AUC of 0.94 and improved classification performance by up to 3% compared with single-modality models, demonstrating enhanced robustness and sensitivity to early-stage disease. Full article
(This article belongs to the Section Animal Welfare)
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24 pages, 6343 KB  
Article
Visual Perception Promotes Active Health: A Psychophysiological Study of Micro Public Space Design in High-Density Urban Areas
by Ping Shu, Zihua Jin, Yaxin Li and Huairou Li
Sustainability 2026, 18(3), 1298; https://doi.org/10.3390/su18031298 - 28 Jan 2026
Viewed by 113
Abstract
Rapid urbanization and spatial constraints in high-density residential areas pose significant challenges to public health and well-being. This study investigates the mechanisms by which the visual environment of urban micro public spaces shapes residents’ psychophysiological responses to encourage spontaneous physical activity and advance [...] Read more.
Rapid urbanization and spatial constraints in high-density residential areas pose significant challenges to public health and well-being. This study investigates the mechanisms by which the visual environment of urban micro public spaces shapes residents’ psychophysiological responses to encourage spontaneous physical activity and advance active health. Using machine learning and semantic segmentation, 9 core visual elements across 20 micro public space scenes in high-density urban neighborhoods were quantified. An immersive virtual reality (VR) experiment was conducted, collecting synchronized multimodal psychophysiological data from 60 participants, which yielded 600 valid observations. Through an analytical framework combining Self-Organizing Map (SOM) clustering and Random Forest (RF) modeling, three distinct functional archetypes were identified: Restoration-Supporting, Activity-Promoting, and Stress-Inducing. The Activity-Promoting archetype was most effective in fostering spontaneous activity intention, characterized by a high proportion of activity areas, a moderate sky view factor, and minimal physical barriers. RF modeling further pinpointed pedestrian density, activity area ratio, and green space ratio as key visual drivers of health-promoting outcomes. Based on these findings, a “Visual Activation for Active Health” framework is proposed. It posits that moderate visual-environmental stimulation is the core mechanism for transforming passive spaces into health-promotive settings, thereby establishing a theoretical foundation for the evidence-based design of healthy and sustainable urban environments. Full article
(This article belongs to the Special Issue Sustainable Urban Designs to Enhance Human Health and Well-Being)
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32 pages, 3217 KB  
Review
Architecting the Orthopedical Clinical AI Pipeline: A Review of Integrating Foundation Models and FHIR for Agentic Clinical Assistants and Digital Twins
by Assiya Boltaboyeva, Zhanel Baigarayeva, Baglan Imanbek, Bibars Amangeldy, Nurdaulet Tasmurzayev, Kassymbek Ozhikenov, Zhadyra Alimbayeva, Chingiz Alimbayev and Nurgul Karymsakova
Algorithms 2026, 19(2), 99; https://doi.org/10.3390/a19020099 - 27 Jan 2026
Viewed by 223
Abstract
The exponential growth of multimodal orthopedic data, ranging from longitudinal Electronic Health Records to high-resolution musculoskeletal imaging, has rendered manual analysis insufficient. This has established Large Language Models (LLMs) as algorithmically necessary for managing healthcare complexity. However, their deployment in high-stakes surgical environments [...] Read more.
The exponential growth of multimodal orthopedic data, ranging from longitudinal Electronic Health Records to high-resolution musculoskeletal imaging, has rendered manual analysis insufficient. This has established Large Language Models (LLMs) as algorithmically necessary for managing healthcare complexity. However, their deployment in high-stakes surgical environments presents a fundamental algorithmic paradox: while generic foundation models possess vast reasoning capabilities, they often lack the precise, protocol-driven domain knowledge required for safe orthopedic decision support. This review provides a structured synthesis of the emerging algorithmic frameworks required to build modern clinical AI assistants. We deconstruct current methodologies into their core components: large-language-model adaptation, multimodal data fusion, and standardized data interoperability pipelines. Rather than proposing a single proprietary architecture, we analyze how recent literature connects specific algorithmic choices such as the trade-offs between full fine-tuning and Low-Rank Adaptation to their computational costs and factual reliability. Furthermore, we examine the theoretical architectures required for ‘agentic’ capabilities, where AI systems integrate outputs from deep convolutional neural networks and biosensors. The review concludes by outlining the unresolved challenges in algorithmic bias, security, and interoperability that must be addressed to transition these technologies from research prototypes to scalable clinical solutions. Full article
(This article belongs to the Special Issue Artificial Intelligence Algorithms for Healthcare: 2nd Edition)
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21 pages, 1214 KB  
Review
Large Language Models in Cardiovascular Prevention: A Narrative Review and Governance Framework
by José Ferreira Santos and Hélder Dores
Diagnostics 2026, 16(3), 390; https://doi.org/10.3390/diagnostics16030390 - 26 Jan 2026
Viewed by 259
Abstract
Background: Large language models (LLMs) are becoming progressively integrated into clinical practice; however, their role in cardiovascular (CV) prevention remains unclear. This review synthesizes current evidence on LLM applications in preventive cardiology and proposes a governance framework for their safe translation into practice. [...] Read more.
Background: Large language models (LLMs) are becoming progressively integrated into clinical practice; however, their role in cardiovascular (CV) prevention remains unclear. This review synthesizes current evidence on LLM applications in preventive cardiology and proposes a governance framework for their safe translation into practice. Methods: We conducted a comprehensive narrative review of literature published between January 2015 and November 2025. Evidence was synthesized across three functional domains: (1) patient applications for health literacy and behavior change; (2) clinician applications for decision support and workflow efficiency; and (3) system applications for automated data extraction, registry construction, and quality surveillance. Results: Evidence suggests that while LLMs generate empathetic, guideline-concordant patient education, they lack the nuance required for unsupervised, personalized advice. For clinicians, LLMs effectively summarize clinical notes and draft documentation but remain unreliable for deterministic risk calculations and autonomous decision-making. System-facing applications demonstrate potential for automated phenotyping and multimodal risk prediction. However, safe deployment is constrained by hallucinations, temporal obsolescence, automation bias, and data privacy concerns. Conclusions: LLMs could help mitigate structural barriers in CV prevention but should presently be deployed only as supervised “reasoning engines” that augment, rather than replace, clinician judgment. To guide the transition from in silico performance to bedside practice, we propose the C.A.R.D.I.O. framework (Clinical validation, Auditability, Risk stratification, Data privacy, Integration, and Ongoing vigilance) as a roadmap for responsible integration. Full article
(This article belongs to the Special Issue Artificial Intelligence and Computational Methods in Cardiology 2026)
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17 pages, 642 KB  
Review
Application of Artificial Intelligence in Social Media Depression Detection: A Narrative Review from Temporal Analysis
by Francesco Sacchini, Federico Biondini, Giovanni Cangelosi, Sara Morales Palomares, Stefano Mancin, Mauro Parozzi, Gabriele Caggianelli, Sophia Russotto, Alice Masini, Diego Lopane and Fabio Petrelli
Psychiatry Int. 2026, 7(1), 24; https://doi.org/10.3390/psychiatryint7010024 - 26 Jan 2026
Viewed by 215
Abstract
Background: Depression remains a major global mental health concern, significantly intensified during the COVID-19 pandemic. As social media usage surged during this period, it emerged as a valuable source for identifying early signs of depression. Artificial intelligence (AI) offers powerful tools to analyze [...] Read more.
Background: Depression remains a major global mental health concern, significantly intensified during the COVID-19 pandemic. As social media usage surged during this period, it emerged as a valuable source for identifying early signs of depression. Artificial intelligence (AI) offers powerful tools to analyze large volumes of user-generated content, enabling timely and effective detection of depressive symptoms. This review aims to preliminarily explore and compare evidence on the use of AI models for detecting depression in social content across the pre-, during, and post-pandemic phases, assessing their effectiveness and limitations. Methods: A narrative literature review was conducted using PubMed and Scopus, following the SANRA guidelines to ensure methodological quality and reproducibility. The study was pre-registered in the OSF database and employed the PICOS framework for the strategy. Inclusion criteria comprised studies in English from the past 10 years that analyzed depression detection via AI, machine learning (ML), and deep learning (DL) applied to textual data, images, and social metadata. This review addresses the following four research questions: (1) whether AI models improved effectiveness in detecting depression during/after the pandemic vs. pre-pandemic; (2) whether textual, visual, or multimodal data approaches became more effective during the pandemic; (3) whether AI models better addressed technical challenges (data quality/diversity) post-pandemic; and (4) whether strategies for responsible AI implementation improved during/after the pandemic. Results: Out of 349 identified records, nine primary studies were included, as most excluded articles had a predominantly technical focus and did not meet the clinical relevance criteria. AI models demonstrated strong potential in detecting depression, particularly through text-based classification and social content analysis. Several studies reported high predictive performance, with notable improvements in accuracy and sensitivity during and after the pandemic, although evidence remains limited. Conclusions: Our preliminary analysis suggests that AI-based depression detection on social media shows potential for clinical use, highlighting interdisciplinary collaboration, ethical considerations, and patient-centered approaches. These findings require confirmation and validation through larger, well-designed systematic reviews. Full article
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20 pages, 49658 KB  
Article
Dead Chicken Identification Method Based on a Spatial-Temporal Graph Convolution Network
by Jikang Yang, Chuang Ma, Haikun Zheng, Zhenlong Wu, Xiaohuan Chao, Cheng Fang and Boyi Xiao
Animals 2026, 16(3), 368; https://doi.org/10.3390/ani16030368 - 23 Jan 2026
Viewed by 148
Abstract
In intensive cage rearing systems, accurate dead hen detection remains difficult due to complex environments, severe occlusion, and the high visual similarity between dead hens and live hens in a prone posture. To address these issues, this study proposes a dead hen identification [...] Read more.
In intensive cage rearing systems, accurate dead hen detection remains difficult due to complex environments, severe occlusion, and the high visual similarity between dead hens and live hens in a prone posture. To address these issues, this study proposes a dead hen identification method based on a Spatial-Temporal Graph Convolutional Network (STGCN). Unlike conventional static image-based approaches, the proposed method introduces temporal information to enable dynamic spatial-temporal modeling of hen health states. First, a multimodal fusion algorithm is applied to visible light and thermal infrared images to strengthen multimodal feature representation. Then, an improved YOLOv7-Pose algorithm is used to extract the skeletal keypoints of individual hens, and the ByteTrack algorithm is employed for multi-object tracking. Based on these results, spatial-temporal graph-structured data of hens are constructed by integrating spatial and temporal dimensions. Finally, a spatial-temporal graph convolution model is used to identify dead hens by learning spatial-temporal dependency features from skeleton sequences. Experimental results show that the improved YOLOv7-Pose model achieves an average precision (AP) of 92.8% in keypoint detection. Based on the constructed spatial-temporal graph data, the dead hen identification model reaches an overall classification accuracy of 99.0%, with an accuracy of 98.9% for the dead hen category. These results demonstrate that the proposed method effectively reduces interference caused by feeder occlusion and ambiguous visual features. By using dynamic spatial-temporal information, the method substantially improves robustness and accuracy of dead hen detection in complex cage rearing environments, providing a new technical route for intelligent monitoring of poultry health status. Full article
(This article belongs to the Special Issue Welfare and Behavior of Laying Hens)
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23 pages, 1377 KB  
Review
Healthcare Decarbonisation Education for Health Profession Students: A Scoping Review
by Nuala McLaughlin-Borlace, Gary Mitchell, Nuala Flood, Laura Steele, Tara Anderson, Fadwa Al Halaiqa, Dalal Hammoudi Halat, Norfadzilah Binti Ahmad, Tracy Levett-Jones, Jesús Sánchez-Martín and Stephanie Craig
Sustainability 2026, 18(2), 1068; https://doi.org/10.3390/su18021068 - 21 Jan 2026
Viewed by 162
Abstract
Climate change is the greatest health threat of the 21st century, with healthcare contributing approximately 4–5% of global greenhouse gas emissions. Decarbonising healthcare, the deliberate reduction of emissions across all healthcare activities, is essential to reduce the health sector’s environmental impact while maintaining [...] Read more.
Climate change is the greatest health threat of the 21st century, with healthcare contributing approximately 4–5% of global greenhouse gas emissions. Decarbonising healthcare, the deliberate reduction of emissions across all healthcare activities, is essential to reduce the health sector’s environmental impact while maintaining equitable, high-quality care. Preparing future health professionals for sustainable, low-carbon practice is increasingly recognised as critical; however, education on healthcare decarbonisation remains inconsistent and weakly embedded in curricula. This scoping review mapped existing educational resources for pre-registration health profession students. Following the JBI methodology, six databases (Scopus, Web of Science, MEDLINE, CINAHL, PsycINFO, and GreenFILE) were searched in April 2025 (updated in October 2025). Data were thematically analysed. In total, 32 studies met inclusion criteria, comprising 17 mixed-methods, 11 quantitative, and 4 qualitative designs. Most interventions were multimodal, addressing sustainability or climate change through simulation, digital, formal, or didactic methods. Knowledge and attitudes were the most frequently evaluated outcomes. Thematic analysis identified knowledge and awareness, attitudes and emotional responses, behavioural intent and action, identity formation through collaborative learning, and barriers to decarbonisation. Findings suggest that blended, interactive, and technology-enhanced education improves knowledge, attitudes, and identity, but sustained impact requires longitudinal, skills-based, and policy-aligned interventions to drive meaningful healthcare decarbonisation action. Full article
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9 pages, 630 KB  
Perspective
Digital-Intelligent Precision Health Management: An Integrative Framework for Chronic Disease Prevention and Control
by Yujia Ma, Dafang Chen and Jin Xie
Biomedicines 2026, 14(1), 223; https://doi.org/10.3390/biomedicines14010223 - 20 Jan 2026
Viewed by 249
Abstract
Non-communicable diseases (NCDs) impose an overwhelming burden on global health systems. Prevailing healthcare for NCDs remains largely hospital-centered, episodic, and reactive, rendering them poorly suited to address the long-term, heterogeneous, and multifactorial nature of NCDs. Rapid advances in digital technologies, artificial intelligence (AI), [...] Read more.
Non-communicable diseases (NCDs) impose an overwhelming burden on global health systems. Prevailing healthcare for NCDs remains largely hospital-centered, episodic, and reactive, rendering them poorly suited to address the long-term, heterogeneous, and multifactorial nature of NCDs. Rapid advances in digital technologies, artificial intelligence (AI), and precision medicine have catalyzed the development of an integrative framework for digital-intelligent precision health management, characterized by the functional integration of data, models, and decision support. It is best understood as an integrated health management framework operating across three interdependent dimensions. First, it is grounded in multidimensional health-related phenotyping, enabled by continuous digital sensing, wearable and ambient devices, and multi-omics profiling, which together allow for comprehensive, longitudinal characterization of individual health states in real-world settings. Second, it leverages intelligent risk warning and early diagnosis, whereby multimodal data are fused using advanced machine learning algorithms to generate dynamic risk prediction, detect early pathological deviations, and refine disease stratification beyond conventional static models. Third, it culminates in health management under intelligent decision-making, integrating digital twins and AI health agents to support personalized intervention planning, virtual simulation, adaptive optimization, and closed-loop management across the disease continuum. Framed in this way, digital-intelligent precision health management enables a fundamental shift from passive care towards proactive, anticipatory, and individual-centered health management. This Perspectives article synthesizes recent literature from the past three years, critically examines translational and ethical challenges, and outlines future directions for embedding this framework within population health and healthcare systems. Full article
(This article belongs to the Section Molecular and Translational Medicine)
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28 pages, 435 KB  
Review
Advances in Audio Classification and Artificial Intelligence for Respiratory Health and Welfare Monitoring in Swine
by Md Sharifuzzaman, Hong-Seok Mun, Eddiemar B. Lagua, Md Kamrul Hasan, Jin-Gu Kang, Young-Hwa Kim, Ahsan Mehtab, Hae-Rang Park and Chul-Ju Yang
Biology 2026, 15(2), 177; https://doi.org/10.3390/biology15020177 - 18 Jan 2026
Viewed by 333
Abstract
Respiratory diseases remain one of the most significant health challenges in modern swine production, leading to substantial economic losses, compromised animal welfare, and increased antimicrobial use. In recent years, advances in artificial intelligence (AI), particularly machine learning and deep learning, have enabled the [...] Read more.
Respiratory diseases remain one of the most significant health challenges in modern swine production, leading to substantial economic losses, compromised animal welfare, and increased antimicrobial use. In recent years, advances in artificial intelligence (AI), particularly machine learning and deep learning, have enabled the development of non-invasive, continuous monitoring systems based on pig vocalizations. Among these, audio-based technologies have emerged as especially promising tools for early detection and monitoring of respiratory disorders under real farm conditions. This review provides a comprehensive synthesis of AI-driven audio classification approaches applied to pig farming, with focus on respiratory health and welfare monitoring. First, the biological and acoustic foundations of pig vocalizations and their relevance to health and welfare assessment are outlined. The review then systematically examines sound acquisition technologies, feature engineering strategies, machine learning and deep learning models, and evaluation methodologies reported in the literature. Commercially available systems and recent advances in real-time, edge, and on-farm deployment are also discussed. Finally, key challenges related to data scarcity, generalization, environmental noise, and practical deployment are identified, and emerging opportunities for future research including multimodal sensing, standardized datasets, and explainable AI are highlighted. This review aims to provide researchers, engineers, and industry stakeholders with a consolidated reference to guide the development and adoption of robust AI-based acoustic monitoring systems for respiratory health management in swine. Full article
(This article belongs to the Section Zoology)
45 pages, 9328 KB  
Review
Advancements in Machine Learning-Assisted Flexible Electronics: Technologies, Applications, and Future Prospects
by Hao Su, Hongcun Wang, Dandan Sang, Santosh Kumar, Dao Xiao, Jing Sun and Qinglin Wang
Biosensors 2026, 16(1), 58; https://doi.org/10.3390/bios16010058 - 13 Jan 2026
Viewed by 289
Abstract
The integration of flexible electronics and machine learning (ML) algorithms has become a revolutionary force driving the field of intelligent sensing, giving rise to a new generation of intelligent devices and systems. This article provides a systematic review of core technologies and practical [...] Read more.
The integration of flexible electronics and machine learning (ML) algorithms has become a revolutionary force driving the field of intelligent sensing, giving rise to a new generation of intelligent devices and systems. This article provides a systematic review of core technologies and practical applications of ML in flexible electronics. It focuses on analyzing the theoretical frameworks of algorithms such as the Long Short-Term Memory Network (LSTM), Convolutional Neural Network (CNN), and Reinforcement Learning (RL) in the intelligent processing of sensor signals (IPSS), multimodal feature extraction (MFE), process defect and anomaly detection (PDAD), and data compression and edge computing (DCEC). This study explores the performance advantages of these technologies in optimizing signal analysis accuracy, compensating for interference in high-noise environments, optimizing manufacturing process parameters, etc., and empirically analyzes their potential applications in wearable health monitoring systems, intelligent control of soft robots, performance optimization of self-powered devices, and intelligent perception of epidermal electronic systems. Full article
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34 pages, 5342 KB  
Review
Artificial Intelligence in Medical Diagnostics: Foundations, Clinical Applications, and Future Directions
by Dorota Bartusik-Aebisher, Daniel Roshan Justin Raj and David Aebisher
Appl. Sci. 2026, 16(2), 728; https://doi.org/10.3390/app16020728 - 10 Jan 2026
Viewed by 630
Abstract
Artificial intelligence (AI) is rapidly transforming medical diagnostics by allowing for early, accurate, and data-driven clinical decision-making. This review provides an overview of how machine learning (ML), deep learning, and emerging multimodal foundation models have been used in diagnostic procedures across imaging, pathology, [...] Read more.
Artificial intelligence (AI) is rapidly transforming medical diagnostics by allowing for early, accurate, and data-driven clinical decision-making. This review provides an overview of how machine learning (ML), deep learning, and emerging multimodal foundation models have been used in diagnostic procedures across imaging, pathology, molecular analysis, physiological monitoring, and electronic health record (EHR)-integrated decision-support systems. We have discussed the basic computational foundations of supervised, unsupervised, and reinforcement learning and have also shown the importance of data curation, validation metrics, interpretability methods, and feature engineering. The use of AI in many different applications has shown that it can find abnormalities and integrate some features from multi-omics and imaging, which has shown improvements in prognostic modeling. However, concerns about data heterogeneity, model drift, bias, and strict regulatory guidelines still remain and are yet to be addressed in this field. Looking forward, future advancements in federated learning, generative AI, and low-resource diagnostics will pave the way for adaptable and globally accessible AI-assisted diagnostics. Full article
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18 pages, 1326 KB  
Review
MR-Guided Radiotherapy in Oesophageal Cancer: From Principles to Practice—A Narrative Review
by Su Chen Fong, Eddie Lau, David S. Liu, Niall C. Tebbutt, Richard Khor, Trevor Leong, David Williams, Sergio Uribe and Sweet Ping Ng
Curr. Oncol. 2026, 33(1), 34; https://doi.org/10.3390/curroncol33010034 - 8 Jan 2026
Viewed by 366
Abstract
Oesophageal cancer remains a significant global health burden with poor survival outcomes despite multimodal treatment. Recent advances in magnetic resonance imaging (MRI) have opened opportunities to improve radiotherapy delivery. This review examines the role of MRI and MR-guided radiotherapy (MRgRT) in oesophageal cancer, [...] Read more.
Oesophageal cancer remains a significant global health burden with poor survival outcomes despite multimodal treatment. Recent advances in magnetic resonance imaging (MRI) have opened opportunities to improve radiotherapy delivery. This review examines the role of MRI and MR-guided radiotherapy (MRgRT) in oesophageal cancer, focusing on applications in staging, treatment planning, and response assessment, with particular emphasis on magnetic resonance linear accelerator (MR-Linac)-based delivery. Compared to computed tomography (CT), MRI offers superior soft-tissue contrast, enabling more accurate tumour delineation and the potential for reduced treatment margins. Real-time MR imaging during treatment can facilitate motion management, while daily adaptive planning can accommodate anatomical changes throughout the treatment course. Functional MRI sequences, including diffusion-weighted and dynamic contrast-enhanced imaging, offer quantitative data for treatment response monitoring. Early clinical and dosimetric studies demonstrate that MRgRT can significantly reduce radiation dose to critical organs while maintaining target coverage. However, clinical evidence for MRgRT in oesophageal cancer is limited to small early-phase studies, with no phase II/III trials demonstrating improvements in survival, toxicity, or patient-reported outcomes. Long-term clinical benefits and cost-effectiveness remain unproven, highlighting the need for prospective outcome-focused studies to define the role for MRgRT within multimodality treatment pathways. Full article
(This article belongs to the Special Issue Adaptive Radiotherapy: Advanced Imaging for Personalised Treatment)
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20 pages, 901 KB  
Article
Explainable Transformer-Based Modelling for Pathogen-Oriented Food Safety Inspection Grade Prediction Using New York State Open Data
by Omer Faruk Sari, Mohamed Bader-El-Den and Volkan Ince
Foods 2026, 15(2), 223; https://doi.org/10.3390/foods15020223 - 8 Jan 2026
Viewed by 242
Abstract
Foodborne pathogens remain a major public health concern, and the early identification of unsafe conditions is essential for preventive control. Routine inspections generate rich textual and structured data that can support real-time assessment of pathogen-related risk. The objective of this study is to [...] Read more.
Foodborne pathogens remain a major public health concern, and the early identification of unsafe conditions is essential for preventive control. Routine inspections generate rich textual and structured data that can support real-time assessment of pathogen-related risk. The objective of this study is to develop an explainable transformer-based framework for predicting food safety inspection grades using multimodal inspection data. We combine structured metadata with unstructured deficiency narratives and evaluate classical machine learning models, deep learning architectures, and transformer models. RoBERTa achieved the highest performance (F1 = 0.96), followed by BiLSTM (F1 = 0.95) and LightGBM (F1 = 0.92). SHapley Additive exPlanations (SHAP) analysis revealed linguistically meaningful indicators of pathogen-related hazards such as temperature abuse, pests, and unsanitary practices. The findings demonstrate that transformer-based models, combined with explainable AI (XAI), can support pathogen-oriented monitoring and real-time risk assessment. This study highlights the potential of multimodal AI approaches to enhance inspection efficiency and strengthen public health surveillance. Full article
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