Search Results (8)

Declining proprioceptive function is associated with problems such as lower back pain and falls. Therefore, we developed a vibration device using sweep frequency to evaluate several proprioceptors with different response frequency ranges. This study aimed to elucidate the biological responses of healthy individuals to vibratory stimulation at different sites and frequency ranges and to propose cutoff values to determine the decline in proprioceptive function. Mechanical vibration was separately applied to the lower legs and lower back, and proprioceptive function was evaluated by defining the ratio of the center of pressure (CoP) in the anteroposterior direction during mechanical vibration to that during no vibration in the three frequency ranges. The cut-off value was defined as the mean value, with the standard deviation subtracted for each indicator. The cut-off values were higher in the lower legs than in the lower back at all frequency ranges and in the 30–53 Hz and 56–100 Hz frequency ranges for both the lower legs and lower back. In healthy individuals, 9.9% and 8.6% were below the cut-off values in the 30–53 Hz and 56–100 Hz frequency ranges for the lower legs, respectively. Full article

The management of sexual complications after treatment of localized prostate cancer, such as erectile dysfunction, changes in the length of the penis, pain during sexual intercourse, and lack of orgasm, is still an unsolved problem with an important impact on patients’ quality of life. In this review, we summarize the current scientific literature about the rehabilitation of erectile dysfunction after prostate cancer treatment. The therapy for penile rehabilitation includes different types of treatments: the combination of phosphodiesterase type 5 inhibitors (PDE5-I) and the vacuum erectile device (VED) are considered first-line treatment options. When therapy begins, the duration of treatment, the dosage and the drug used all play very important roles in the treatment outcome. Intracavernous injection (ICI) therapy represents the second-line option for patients ineligible for PDE5-I therapy. Technological development has led to the emergence of devices for the stimulation of the penis without the use of drugs, such as penile vibratory stimulation (PVS) for stimulation of ejaculation in spinal cord injury and low-intensity extracorporeal shockwave therapy (LIESWT). The rapid diffusion of the latter, thanks to its easy use, attains good results without side effects. The panorama of penile rehabilitation after PC treatments is vast and many studies are needed, especially on new technologies, to find the best therapeutic regimen possible, personalized to the patient’s characteristics and the type of treatment for PC. Full article

While vibrotactile stimulation shows promise for sensory substitution devices, a crucial question concerns vibrotactile spatial resolution. We examined the optimum distance between three voice coil actuators (model: lofeltL5) on the forearm. Three actuators were embedded in a fabric-based vibrotactile sleeve where the actuators were placed in enclosures 3D-printed on the fabric. We used the relative point localization method where observers must discriminate whether two successive stimulations are in the same location or not. The resolution was measured for five vibrotactile sleeves, each with different distances between the actuators on the longitudinal axis of the forearm. The various distances were tested in a random order. In experiment one, pairs of stimuli were delivered sequentially in a random order to two adjacent actuators of the tactile sleeve on the upper side of the forearm. The task was to identify the perceived direction of the second stimulation (up, down, or the same) relative to the first one. Experiment two involved the same procedure but for the underside of the forearm. Taking the restrictions of the physical dimensions of the forearm and the design considerations into account, our results suggest that 20 mm is the optimum distance between the voice coil actuators (Model: Lofelt L5) for successful discrimination with high accuracy between the two stimulus locations on the forearm. There were no significant differences between the upper and undersides of the forearm. Full article

This study aimed to assess differences in somatosensory control strategies between older patients with sagittal imbalance and young adults during postural tasks. The center of pressure displacement in 27 older patients with sagittal imbalance and 27 young adults was determined upon standing blindfolded on a balance board. Vibratory stimulation at 56 to 100 Hz was applied bilaterally to the gastrocnemius and soleus muscles (GS) and lumbar multifidus to evaluate the contributions of proprioceptive signals to postural control. Data of older patients and young adults were compared using the Mann–Whitney U-test or independent sample t-tests. Compared with the young adults, the older patients were significantly more reliant on the GS (p < 0.005) for their postural control and showed a higher relative proprioceptive weighting ratio (RPW) (p = 0.038). The postural strategy adopted by the older patients depended on the level of proprioceptive stimulation applied to the GS, and the postural control strategy of the ankle correlated with RPW. Overall, this study identifies RPW as a novel measure of postural strategy in older patients with sagittal imbalance and provides an understanding of strategies used to maintain balance, which may assist in developing preventative measures to reduce the risk of falls. Full article

Postural instability owing to poor proprioception is considered a main cause of low back pain and falls. However, the effect of local vibratory stimulation on a poor proprioceptor on proprioceptive control strategy has yet to be evaluated. Therefore, in this study, we proposed an evaluation method of the immediate effect on proprioceptive control strategies by applying local vibratory stimulation to the poor proprioceptor. First, using our device, we determined the poor proprioceptors in each of six elderly patients with non-specific low back pain. Furthermore, we applied local vibratory stimulation to the poor proprioceptor. Finally, we compared the proprioceptive control strategy before and after applying local vibratory stimulation. As a result, the proprioceptive control strategy improved for three patients with impaired muscle spindles that responded to a higher frequency (p < 0.05). Thus, the impaired proprioceptive control strategy caused by a decline in the muscle spindle responding to a higher frequency might be improved by local vibratory stimulation. Furthermore, it was shown that our developed device and protocol might be used to evaluate proprioceptive control strategies within multiple frequency ranges, as well as activate a poor proprioceptor based on diagnosis and improve the proprioceptive control strategies. Full article

The purpose of this study was to investigate the functional decline in proprioceptors in patients with low back pain (LBP) by evaluating the entire range of response frequencies of proprioceptors. In previous studies, the function of proprioceptors was only evaluated by single frequency vibrations. However, because it is assumed that individual differences exist in response frequencies of proprioceptors, we developed a method using vibration with sweep frequency covering the entire range of response frequencies of proprioceptors. The center of pressure was determined in 35 elderly patients with non-specific LBP (NSLBP) and 28 elderly individuals with non-LBP (NLBP) during upright stances on a balance board without vision. Local vibratory stimulations to lower leg or trunk muscles were continuously varied between 27 and 272 Hz over 60 s to evaluate the proprioceptive predominance of a body location using the relative proprioceptive weighting ratio (RPW). Compared with the NLBP group, the NSLBP group exhibited a lower RPW value for the Vater-Pacini corpuscles. Thus, the NSLBP group relied more on the input of Vater-Pacini corpuscles in the trunk. A reduction in lower leg sensitivity at the Vater-Pacini corpuscles in the NSLBP group was observed. Full article

Proprioceptive input may greatly affect postural stability. However, the proprioceptive postural strategy in elderly, middle-aged, and young people has not been investigated sufficiently. Hence, in this study, we aimed to investigate differences in proprioceptive postural strategies of elderly, middle-aged, and young people. The center of pressure displacement was determined in 23 elderly, 23 middle-aged, and 23 young people during upright stance on a balance board with their eyes closed. Vibratory stimulations at 30, 60, and 240 Hz were applied to the lumbar multifidus (LM) and gastrocnemius (GS) muscles to evaluate the contributions of different proprioceptive signals used in balance control. Compared with middle-aged and young people, elderly people showed a high dependence on postural control of the GS at 30 Hz (p-values: Young and elderly: 0.033; middle-aged and elderly: 0.001). Moreover, compared with young people, elderly people were more dependent on postural control of the LM at 240 Hz (p = 0.016). There were no significant differences with respect to the GS at 60 and 240 Hz, and with respect to the LM at 30 and 60 Hz between the elderly, young, and middle-aged people. Thus, the postural control strategy of elderly people depends on the GS at 30 Hz. Full article

Cell culture and cell scaffold engineering have previously developed in two directions. First can be ‘static into dynamic’, with proven effects that dynamic cultures have benefits over static ones. Researches in this direction have used several mechanical means, like external vibrators or shakers, to approximate the dynamic environments in real tissue, though such approaches could only partly address the issue. Second, can be ‘2D into 3D’, that is, artificially created three-dimensional (3D) passive (also called ‘static’) scaffolds have been utilized for 3D cell culture, helping external culturing conditions mimic real tissue 3D environments in a better way as compared with traditional two-dimensional (2D) culturing. In terms of the fabrication of 3D scaffolds, 3D printing (3DP) has witnessed its high popularity in recent years with ascending applicability, and this tendency might continue to grow along with the rapid development in scaffold engineering. In this review, we first introduce cell culturing, then focus 3D cell culture scaffold, vibration stimulation for dynamic culture, and 3DP technologies fabricating 3D scaffold. Potential interconnection of these realms will be analyzed, as well as the limitations of current 3D scaffold and vibration mechanisms. In the recommendation part, further discussion on future scaffold engineering regarding 3D vibratory scaffold will be addressed, indicating 3DP as a positive bridging technology for future scaffold with integrated and localized vibratory functions. Full article