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  • Article
  • Open Access
15 Citations
4,972 Views
14 Pages

Efficacy of Commercial Infectious Bronchitis Vaccines against Canadian Delmarva (DMV/1639) Infectious Bronchitis Virus Infection in Layers

  • Mohamed S. H. Hassan,
  • Sabrina M. Buharideen,
  • Ahmed Ali,
  • Shahnas M. Najimudeen and ,
  • Dayna Goldsmith,
  • Carla S. Coffin,
  • Susan C. Cork,
  • Frank van der Meer and
  • Mohamed Faizal Abdul-Careem
  • + 4 authors+ 0 author

27 July 2022

Vaccination is the most important way to control infectious bronchitis (IB) in chickens. Since the end of 2015, the Delmarva (DMV)/1639 strain of infectious bronchitis virus (IBV) has caused significant damage to the layer flocks in Eastern Canada. T...

(This article belongs to the Special Issue Immunology and Vaccines against Avian Infectious Diseases)
  • Article
  • Open Access
13 Citations
6,055 Views
20 Pages

Infectious Bronchitis Virus Regulates Cellular Stress Granule Signaling

  • Matthew J. Brownsword,
  • Nicole Doyle,
  • Michèle Brocard,
  • Nicolas Locker and
  • Helena J. Maier

14 May 2020

Viruses must hijack cellular translation machinery to express viral genes. In many cases, this is impeded by cellular stress responses. These stress responses result in the global inhibition of translation and the storage of stalled mRNAs, into RNA-p...

  • Article
  • Open Access
6 Citations
3,132 Views
12 Pages

Development and Immunoprotection of Bacterium-like Particle Vaccine against Infectious Bronchitis in Chickens

  • Pengju Zhang,
  • Tiantian Yang,
  • Yixue Sun,
  • Haiying Qiao and ,
  • Nianzhi Hu,
  • Xintao Li,
  • Weixia Wang,
  • Lichun Zhang and
  • Yanlong Cong
  • + 4 authors+ 0 author

28 July 2023

Infectious bronchitis (IB) is a major threat to the global poultry industry. Despite the availability of commercial vaccines, the IB epidemic has not been effectively controlled. The exploration of novel IBV vaccines may provide a new way to prevent...

(This article belongs to the Section Veterinary Vaccines)
  • Review
  • Open Access
60 Citations
8,062 Views
14 Pages

Infectious bronchitis virus (IBV) is an enveloped and positive-sense single-stranded RNA virus. IBV was the first coronavirus to be discovered and predominantly causes respiratory disease in commercial poultry worldwide. This review summarizes severa...

(This article belongs to the Section Viral Pathogens)
  • Article
  • Open Access
20 Citations
6,148 Views
19 Pages

Limited Cross-Protection against Infectious Bronchitis Provided by Recombinant Infectious Bronchitis Viruses Expressing Heterologous Spike Glycoproteins

  • Sarah Keep,
  • Samantha Sives,
  • Phoebe Stevenson-Leggett,
  • Paul Britton and ,
  • Lonneke Vervelde and
  • Erica Bickerton
  • + 1 author+ 0 author

Gammacoronavirus infectious bronchitis virus (IBV) causes an economically important respiratory disease of poultry. Protective immunity is associated with the major structural protein, spike (S) glycoprotein, which induces neutralising antibodies and...

(This article belongs to the Special Issue Development of Cross-Protective Vaccines)
  • Review
  • Open Access
123 Citations
17,025 Views
20 Pages

Infectious Bronchitis Virus Evolution, Diagnosis and Control

  • Matteo Legnardi,
  • Claudia Maria Tucciarone,
  • Giovanni Franzo and
  • Mattia Cecchinato

RNA viruses are characterized by high mutation and recombination rates, which allow a rapid adaptation to new environments. Most of the emerging diseases and host jumps are therefore sustained by these viruses. Rapid evolution may also hinder the und...

(This article belongs to the Special Issue Trends in Poultry Diseases)
  • Article
  • Open Access
10 Citations
4,536 Views
11 Pages

Antigenic Characterization of Infectious Bronchitis Virus in the South China during 2021–2022

  • Weifeng Yuan,
  • Ting Lv,
  • Weiwei Jiang,
  • Yuechi Hou and ,
  • Qingyi Wang,
  • Jinlian Ren,
  • Lei Fan,
  • Bin Xiang,
  • Qiuyan Lin and
  • Libin Chen
  • + 7 authors+ 2 authors

29 May 2023

Avian infectious bronchitis is a serious and highly contagious disease that is caused by the infectious bronchitis virus (IBV). From January 2021 to June 2022, 1008 chicken tissue samples were collected from various regions of southern China, and 15...

(This article belongs to the Special Issue Enteric and Respiratory Viruses in Animals 2023)
  • Article
  • Open Access
244 Views
14 Pages

Detection of Avian Infectious Bronchitis Virus Genotype GI-13 in the Almaty Region, Kazakhstan

  • Karina Ivanova,
  • Marina Kopochenya,
  • Dinara Naizabayeva and
  • Andrey Zhigailov

Infectious bronchitis remains one of the most economically significant viral diseases in commercial poultry farming, despite the widespread implementation of vaccination programs. The high genetic variability of the infectious bronchitis virus (IBV)...

(This article belongs to the Section Medical and Veterinary Microbiology)
  • Article
  • Open Access
12 Citations
5,044 Views
17 Pages

Salmonella typhimurium Vaccine Candidate Delivering Infectious Bronchitis Virus S1 Protein to Induce Protection

  • Kaihui Liu,
  • Zewei Li,
  • Quan Li,
  • Shifeng Wang and ,
  • Roy Curtiss and
  • Huoying Shi
  • + 1 author+ 0 author

20 January 2024

Infectious bronchitis (IB) is a highly infectious viral disease of chickens which causes significant economic losses in the poultry industry worldwide. An effective vaccine against IB is urgently needed to provide both biosafety and high-efficiency i...

  • Communication
  • Open Access
16 Citations
4,546 Views
10 Pages

Carbonized Lysine-Nanogels Protect against Infectious Bronchitis Virus

  • Ding-Li Chou,
  • Ju-Yi Mao,
  • Anisha Anand,
  • Han-Jia Lin and ,
  • John Han-You Lin,
  • Ching-Ping Tseng,
  • Chih-Ching Huang and
  • Hsian-Yu Wang
  • + 3 authors+ 0 author

In this study, we demonstrate the synthesis of carbonized nanogels (CNGs) from an amino acid (lysine hydrochloride) using a simple pyrolysis method, resulting in effective viral inhibition properties against infectious bronchitis virus (IBV). The vir...

(This article belongs to the Special Issue Molecular and Macromolecular Interactions of Carbon-Based Nanostructures)
  • Article
  • Open Access
42 Citations
5,327 Views
13 Pages

Recombination Events Shape the Genomic Evolution of Infectious Bronchitis Virus in Europe

  • Krisztina Bali,
  • Ádám Bálint,
  • Attila Farsang,
  • Szilvia Marton and ,
  • Borbála Nagy,
  • Eszter Kaszab,
  • Sándor Belák,
  • Vilmos Palya and
  • Krisztián Bányai
  • + 4 authors+ 0 author

24 March 2021

Infectious bronchitis of chicken is a high morbidity and mortality viral disease affecting the poultry industry worldwide; therefore, a better understanding of this pathogen is of utmost importance. The primary aim of this study was to obtain a deepe...

(This article belongs to the Special Issue Genomic Epidemiology of Viral Infections)
  • Article
  • Open Access
15 Citations
4,466 Views
13 Pages

Genetic Analysis of Infectious Bronchitis Virus S1 Gene Reveals Novel Amino Acid Changes in the GI-16 Lineage in Peru

  • Eliana Icochea,
  • Rosa González,
  • Gina Castro-Sanguinetti,
  • Lenin Maturrano and ,
  • Luis Alzamora,
  • Luiz Sesti,
  • Jorge Chacón and
  • Juan More-Bayona
  • + 3 authors+ 0 author

Infectious bronchitis is a highly contagious viral disease that represents an economic threat for poultry despite the wide use of vaccination. To characterize the virus circulating in Peru, we analyzed 200 samples, including nasopharyngeal swabs and...

(This article belongs to the Special Issue Avian Pathogens 2.0)
  • Review
  • Open Access
124 Citations
16,947 Views
17 Pages

22 September 2017

Infectious bronchitis virus (IBV) variants constantly emerge and pose economic threats to poultry farms worldwide. Numerous studies on the molecular and pathogenic characterization of IBV variants have been performed between 2007 and 2017, which we h...

(This article belongs to the Special Issue Molecular Research of Emerging Viruses: Viral Evolution, Diagnostics and Pathogenesis and Therapeutics)
  • Review
  • Open Access
59 Citations
12,675 Views
17 Pages

Infectious Bronchitis Coronavirus Infection in Chickens: Multiple System Disease with Immune Suppression

  • Shahnas M. Najimudeen,
  • Mohamed S. H. Hassan,
  • Susan C. Cork and
  • Mohamed Faizal Abdul-Careem

24 September 2020

In the early 1930s, infectious bronchitis (IB) was first characterized as a respiratory disease in young chickens; later, the disease was also described in older chickens. The etiology of IB was confirmed later as being due to a coronavirus: the infe...

  • Article
  • Open Access
4 Citations
2,822 Views
15 Pages

Infectious bronchitis virus (IBV) causes infectious bronchitis in chicken, an acute, highly contagious respiratory infection. Because of genetic mutations and recombination, IBV forms many subtypes, which makes it difficult to treat the disease and a...

(This article belongs to the Special Issue Poultry Pathogens and Poultry Diseases)
  • Article
  • Open Access
121 Citations
11,168 Views
23 Pages

Recombination in Avian Gamma-Coronavirus Infectious Bronchitis Virus

  • Sharmi W. Thor,
  • Deborah A. Hilt,
  • Jessica C. Kissinger,
  • Andrew H. Paterson and
  • Mark W. Jackwood

23 September 2011

Recombination in the family Coronaviridae has been well documented and is thought to be a contributing factor in the emergence and evolution of different coronaviral genotypes as well as different species of coronavirus. However, there are limited da...

(This article belongs to the Special Issue Recombination in Viruses)
  • Article
  • Open Access
12 Citations
5,042 Views
13 Pages

Immune Responses in Laying Hens after an Infectious Bronchitis Vaccination of Pullets: A Comparison of Two Vaccination Strategies

  • Sabrina M. Buharideen,
  • Mohamed S. H. Hassan,
  • Shahnas M. Najimudeen,
  • Dongyan Niu and ,
  • Markus Czub,
  • Susantha Gomis and
  • Mohamed Faizal Abdul-Careem
  • + 2 authors+ 0 author

For decades, vaccinations have been used to limit infectious bronchitis (IB) in both the broiler and layer industries. Depending on the geographical area, live attenuated vaccines are used either alone or in combination with inactivated vaccines to c...

(This article belongs to the Special Issue Poultry Vaccines)
  • Article
  • Open Access
8 Citations
6,499 Views
19 Pages

Efficacy of Two Vaccination Strategies against Infectious Bronchitis in Laying Hens

  • Ahmed Ali,
  • Mohamed S. H. Hassan,
  • Shahnas M. Najimudeen,
  • Muhammad Farooq and ,
  • Salama Shany,
  • Mounir Mohamed El-Safty,
  • Adel A. Shalaby and
  • Mohamed Faizal Abdul-Careem
  • + 3 authors+ 0 author

2 February 2023

Vaccination remains the leading control method against infectious bronchitis (IB) in poultry despite the frequently observed IB outbreaks in vaccinated flocks. Here, two vaccination regimes were evaluated against challenge with the Massachusetts (Mas...

(This article belongs to the Special Issue Immunology and Vaccines against Avian Infectious Diseases)
  • Article
  • Open Access
565 Views
14 Pages

23 July 2026

In recent years, Riemerella anatipestifer (RA) has been detected with increasing frequency in layer chick flocks. RA infection can lead to reproductive tract lesions, including salpingitis. Epidemiological surveillance further indicates that RA infec...

(This article belongs to the Section Poultry)
  • Review
  • Open Access
24 Citations
7,801 Views
9 Pages

17 December 2020

Infectious bronchitis virus (IBV) is a highly evolving avian pathogen that has increasingly imposed a negative impact on poultry industry worldwide. In the last 20 years, IBV has been continuously circulating among chicken flocks in Egypt causing hug...

(This article belongs to the Section Veterinary Microbiology, Parasitology and Immunology)
  • Review
  • Open Access
32 Citations
5,611 Views
9 Pages

7 November 2020

Infectious bronchitis virus (IBV) remains one of the most important diseases impacting poultry today. Its high adaptive capacity, attributable to the high mutation rate associated with its ssRNA(+), is one of its more important features. While biosec...

(This article belongs to the Special Issue Advances in Avian Diseases Research)
  • Article
  • Open Access
6 Citations
4,516 Views
17 Pages

An Investigation of the Antiviral Potential of Phytocompounds against Avian Infectious Bronchitis Virus through Template-Based Molecular Docking and Molecular Dynamics Simulation Analysis

  • Irfan Gul,
  • Amreena Hassan,
  • Ehtishamul Haq,
  • Syed Mudasir Ahmad and ,
  • Riaz Ahmad Shah,
  • Nazir Ahmad Ganai,
  • Naveed Anjum Chikan,
  • Mohamed Faizal Abdul-Careem and
  • Nadeem Shabir
  • + 4 authors+ 0 author

26 March 2023

Vaccination is widely used to control Infectious Bronchitis in poultry; however, the limited cross-protection and safety issues associated with these vaccines can lead to vaccination failures. Keeping these limitations in mind, the current study expl...

(This article belongs to the Special Issue Avian Respiratory Viruses, Volume III)
  • Article
  • Open Access
1,492 Views
21 Pages

Inhibiting Infectious Bronchitis Virus PLpro Using Ubiquitin Variants

  • Vera J. E. van Vliet,
  • Olivia Roscow,
  • Kihun Kim,
  • Brian L. Mark and ,
  • Marjolein Kikkert and
  • Christine Tait-Burkard
  • + 1 author+ 0 author

Infectious bronchitis virus (IBV) is a coronavirus first isolated in the 1930s infecting chickens. IBV causes great economic losses to the global poultry industry, as it affects egg production and causes mortality by leaving the host susceptible to s...

(This article belongs to the Special Issue Interactions Between Microbes and Hosts: Physiology, Pathology and Treatment)
  • Article
  • Open Access
4 Citations
2,106 Views
16 Pages

Identification of B-Cell Epitopes Located on the Surface of the S1 Protein of Infectious Bronchitis Virus M41 Strains

  • Zichen Gao,
  • Jianing Hu,
  • Yiqin Cai,
  • Ye Liu and ,
  • Guihu Yin,
  • Xinyu Guo,
  • Ruiying Wang,
  • Meng Zhong,
  • Qingtao Liu and
  • Xiuli Feng
  • + 5 authors+ 0 author

24 March 2025

Avian infectious bronchitis is caused by the avian infectious bronchitis virus (IBV), which poses a significant threat to the poultry industry and public health. The S1 protein of IBV plays a crucial role in the process of the virus invading host cel...

(This article belongs to the Section Animal Viruses)
  • Article
  • Open Access
12 Citations
5,970 Views
14 Pages

Comparison of Immune-Related Gene Expression in Two Chicken Breeds Following Infectious Bronchitis Virus Vaccination

  • Schwann Chuwatthanakhajorn,
  • Chi-Sheng Chang,
  • Kannan Ganapathy,
  • Pin-Chi Tang and
  • Chih-Feng Chen

15 May 2023

This study aims to identify the immune-related genes and the corresponding biological pathways following infectious bronchitis virus vaccination in Taiwan Country and White Leghorn chicken breeds. Transcriptomic analyses of the spleen of these two br...

(This article belongs to the Special Issue Genetic Analysis of Important Traits in Poultry)
  • Article
  • Open Access
10 Citations
4,604 Views
17 Pages

Impact of Maternal Antibodies on Infectious Bronchitis Virus (IBV) Infection in Primary and Secondary Lymphoid Organs of Chickens

  • Ishara M. Isham,
  • Mohamed S. H. Hassan,
  • Reham M. Abd-Elsalam,
  • Hiruni A. Ranaweera and ,
  • Motamed E. Mahmoud,
  • Shahnas M. Najimudeen,
  • Awais Ghaffar,
  • Susan C. Cork,
  • Ashish Gupta and
  • Mohamed Faizal Abdul-Careem
  • + 5 authors+ 0 author

7 July 2023

Infectious bronchitis virus (IBV) causes infectious bronchitis disease in chickens. IBV primarily infects the upper respiratory tract and then disseminates to other body systems including gastrointestinal, reproductive, and urinary systems. Unlike or...

(This article belongs to the Special Issue Veterinary Research in Poultry and Livestock Infectious Disease)
  • Article
  • Open Access
26 Citations
5,607 Views
14 Pages

Antigenic and Pathogenic Characteristics of QX-Type Avian Infectious Bronchitis Virus Strains Isolated in Southwestern China

  • Shuyun Li,
  • Lijing Du,
  • Jing Xia,
  • Jiteng Du and ,
  • Guojin You,
  • Yiping Wen,
  • Xiaobo Huang,
  • Qing Zhao,
  • Xinfeng Han and
  • Yong Huang
  • + 9 authors+ 4 authors

13 December 2019

The QX-type avian infectious bronchitis virus (IBV) is still a prevalent genotype in Southwestern China. To analyze the antigenicity and pathogenicity characteristics of the dominant genotype strains (QX-type), S1 gene sequence analysis, virus cross-...

(This article belongs to the Section Animal Viruses)
  • Article
  • Open Access
31 Citations
5,683 Views
10 Pages

A Novel Immunochromatographic Strip for Antigen Detection of Avian Infectious Bronchitis Virus

  • I-Li Liu,
  • Yi-Chun Lin,
  • Yong-Chong Lin,
  • Cai-Zhen Jian and ,
  • Ivan-Chen Cheng and
  • Hui-Wen Chen
  • + 1 author+ 0 author

Avian infectious bronchitis virus (IBV) causes considerable economic losses in the poultry industry worldwide, including Taiwan. IBV is among the most important pathogens in chickens, and it spreads rapidly among flocks. In addition to dozens of know...

(This article belongs to the Special Issue Molecular Research in Emerging Viruses 2019)
  • Article
  • Open Access
23 Citations
5,233 Views
12 Pages

Virulence Properties of GI-23 Infectious Bronchitis Virus Isolated in Poland and Efficacy of Different Vaccination strategies

  • Anna Lisowska,
  • Anna Pikuła,
  • Justyna Opolska,
  • Agnieszka Jasik and ,
  • Anna Kycko and
  • Katarzyna Domańska-Blicharz
  • + 1 author+ 0 author

Infectious bronchitis virus (IBV) is one of the most important poultry pathogens, leading significant economic losses worldwide. IBV is characterised by highly genetic, serotype, and pathotypic variability. Despite extensive immunoprophylaxis strateg...

(This article belongs to the Section Viral Pathogens)
  • Article
  • Open Access
23 Citations
4,090 Views
12 Pages

Genetic Analysis of the Complete S1 Gene in Japanese Infectious Bronchitis Virus Strains

  • Masaji Mase,
  • Kanae Hiramatsu,
  • Satoko Watanabe and
  • Hiroshi Iseki

29 March 2022

The complete nucleotide sequence of the S1 glycoprotein gene of the Japanese infectious bronchitis virus (IBV) strains was determined and genetically analyzed. A total of 61 Japanese IBV strains were classified into seven genotypes, namely GI-1, 3, 7...

(This article belongs to the Special Issue State-of-the-Art Avian Viruses Research in Asia)
  • Article
  • Open Access
38 Citations
9,958 Views
19 Pages

A Multi-Omics Study of Chicken Infected by Nephropathogenic Infectious Bronchitis Virus

  • Puzhi Xu,
  • Ping Liu,
  • Changming Zhou,
  • Yan Shi and ,
  • Qingpeng Wu,
  • Yitian Yang,
  • Guyue Li,
  • Guoliang Hu and
  • Xiaoquan Guo
  • + 4 authors+ 0 author

16 November 2019

Chicken gout resulting from nephropathogenic infectious bronchitis virus (NIBV) has become a serious kidney disease problem in chicken worldwide with alterations of the metabolic phenotypes in multiple metabolic pathways. To investigate the mechanism...

(This article belongs to the Section Animal Viruses)
  • Review
  • Open Access
36 Citations
6,316 Views
11 Pages

26 August 2021

Avian infectious bronchitis virus (IBV) is an important gammacoronavirus. The virus is highly contagious, can infect chickens of all ages, and causes considerable economic losses in the poultry industry worldwide. In the last few decades, numerous st...

(This article belongs to the Special Issue State-of-the-Art Livestock and Poultry Coronaviruses Research in China)
  • Article
  • Open Access
50 Citations
8,775 Views
14 Pages

Evolutionary Analysis of Infectious Bronchitis Virus Reveals Marked Genetic Diversity and Recombination Events

  • Mohammed A. Rohaim,
  • Rania F. El Naggar,
  • Mohammed A. Abdelsabour,
  • Mahmoud H. A. Mohamed and ,
  • Ibrahim M. El-Sabagh and
  • Muhammad Munir
  • + 1 author+ 0 author

29 May 2020

In the last 5 years, frequent outbreaks of infectious bronchitis virus (IBV) are observed in both broiler and layer chicken flocks in the Kingdom of Saudi Arabia (KSA) in spite of extensive usage of vaccines. The IBV is a widespread avian coronavirus...

(This article belongs to the Special Issue Microbial Genomics and Evolution)
  • Article
  • Open Access
16 Citations
5,290 Views
21 Pages

Comparison of Infectious Bronchitis Virus (IBV) Pathogenesis and Host Responses in Young Male and Female Chickens

  • Ishara M. Isham,
  • Reham M. Abd-Elsalam,
  • Motamed E. Mahmoud,
  • Shahnas M. Najimudeen and ,
  • Hiruni A. Ranaweera,
  • Ahmed Ali,
  • Mohamed S. H. Hassan,
  • Susan C. Cork,
  • Ashish Gupta and
  • Mohamed Faizal Abdul-Careem
  • + 5 authors+ 0 author

22 November 2023

Infectious bronchitis virus (IBV) is an avian coronavirus that causes a disease in chickens known as infectious bronchitis (IB). The pathogenesis of IBV and the host immune responses against it depend on multiple factors such as the IBV variant, bree...

(This article belongs to the Special Issue Recent Advances of Avian Viruses Research)
  • Article
  • Open Access
53 Citations
6,461 Views
16 Pages

Delmarva (DMV/1639) Infectious Bronchitis Virus (IBV) Variants Isolated in Eastern Canada Show Evidence of Recombination

  • Mohamed S. H. Hassan,
  • Davor Ojkic,
  • Carla S. Coffin,
  • Susan C. Cork and ,
  • Frank van der Meer and
  • Mohamed Faizal Abdul-Careem
  • + 1 author+ 0 author

13 November 2019

Infectious bronchitis virus (IBV) infection in chickens can lead to an economically important disease, namely, infectious bronchitis (IB). New IBV variants are continuously emerging, which complicates vaccination-based IB control. In this study, five...

(This article belongs to the Special Issue Avian Respiratory Viruses)
  • Article
  • Open Access
13 Citations
3,348 Views
13 Pages

Infectious Bronchitis Coronavirus: Genome Evolution in Vaccinated and Non-Vaccinated SPF Chickens

  • Alexandre Flageul,
  • Chantal Allée,
  • Céline Courtillon,
  • Véronique Béven and ,
  • Hélène Quenault,
  • Yannick Blanchard,
  • Michel Amelot,
  • David Courtois,
  • Sjaak De Wit and
  • Paul A. Brown
  • + 7 authors+ 2 authors

25 June 2022

Infectious Bronchitis virus (IBV) continues to cause significant economic losses for the chicken industry despite the use of many live IBV vaccines around the world. Several authors have suggested that vaccine-induced partial protection may contribut...

(This article belongs to the Special Issue Viral and Host Factors Driving the Emergence and the Evolution of the SARS-CoV-2 and Other Coronaviruses)
  • Article
  • Open Access
3 Citations
2,851 Views
16 Pages

Interaction Network Characterization of Infectious Bronchitis Virus Nsp2 with Host Proteins

  • Mengmeng Wang,
  • Zongyi Bo,
  • Chengcheng Zhang,
  • Mengjiao Guo and ,
  • Yantao Wu and
  • Xiaorong Zhang
  • + 1 author+ 0 author

31 October 2024

Infectious bronchitis (IB) is a highly contagious acute viral disease that leads to substantial economic losses in the poultry industry. Previous research conducted in our laboratory has indicated that Nsp2 may serve as a key virulence factor within...

(This article belongs to the Section Veterinary Microbiology, Parasitology and Immunology)
  • Article
  • Open Access
2 Citations
1,616 Views
13 Pages

Infectious Bronchitis Virus Activates the Aryl Hydrocarbon Receptor During In Vitro Infection

  • Mingjing Zhang,
  • Zhichao Cai,
  • Hongliu An,
  • Rong He and ,
  • Songbai Zhang and
  • Shouguo Fang
  • + 1 author+ 0 author

24 September 2025

Coronaviruses, including avian infectious bronchitis virus (IBV), utilize host cellular pathways to evade the host immune response. The aryl hydrocarbon receptor (AhR), a key antiviral regulator exploited by mammalian coronaviruses like SARS-CoV-2, r...

  • Article
  • Open Access
2,110 Views
15 Pages

22 January 2026

Infectious Bronchitis Virus is one of several major viral infections in poultry, affecting the respiratory, reproductive, and renal systems and causing significant economic losses worldwide. Current vaccines, including the H120 strain, provide limite...

(This article belongs to the Section Poultry)
  • Article
  • Open Access
18 Citations
8,425 Views
17 Pages

Infectious Bronchitis Virus Nonstructural Protein 4 Alone Induces Membrane Pairing

  • Nicole Doyle,
  • Benjamin W. Neuman,
  • Jennifer Simpson,
  • Philippa C. Hawes and ,
  • Judith Mantell,
  • Paul Verkade,
  • Hasan Alrashedi and
  • Helena J. Maier
  • + 3 authors+ 0 author

6 September 2018

Positive-strand RNA viruses, such as coronaviruses, induce cellular membrane rearrangements during replication to form replication organelles allowing for efficient viral RNA synthesis. Infectious bronchitis virus (IBV), a pathogenic avian Gammacoron...

(This article belongs to the Section Animal Viruses)
  • Article
  • Open Access
572 Views
17 Pages

Occurrence of Antibody-Dependent Enhancement of Avian Infectious Bronchitis in Target Animal Experiments

  • Lin Cheng,
  • Di Wang,
  • Jia-Rui Zhang,
  • Yi-Han Zhang and ,
  • Xin-Rui Wu,
  • Ya-Mei Huang,
  • Min Li,
  • Fu-Yan Wang,
  • Yang Zhao and
  • Jing Xia
  • + 8 authors+ 3 authors

Outbreaks of avian infectious bronchitis virus (IBV) often occur in vaccinated flocks. The antibody-dependent enhancement (ADE) has been proposed as a potential mechanism underlying coronavirus vaccine failure. However, this hypothesis has yet to be...

(This article belongs to the Special Issue Pathogenesis and Immune Responses of Viral Infections in Poultry and Wild Birds)
  • Article
  • Open Access
5 Citations
3,520 Views
22 Pages

17 November 2024

Background/Objectives: Infectious bronchitis (IB) is a highly infectious avian disease caused by the infectious bronchitis virus (IBV). The disease causes lesions mainly in the respiratory, reproductive, and renal systems and has a significant econom...

(This article belongs to the Section Viral Genomics)
  • Article
  • Open Access
51 Citations
14,918 Views
14 Pages

The S2 Subunit of QX-type Infectious Bronchitis Coronavirus Spike Protein Is an Essential Determinant of Neurotropism

  • Jinlong Cheng,
  • Ye Zhao,
  • Gang Xu,
  • Keran Zhang and ,
  • Wenfeng Jia,
  • Yali Sun,
  • Jing Zhao,
  • Jia Xue,
  • Yanxin Hu and
  • Guozhong Zhang
  • + 5 authors+ 0 author

22 October 2019

Some coronaviruses (CoVs) have an extra furin cleavage site (RRKR/S, furin-S2′ site) upstream of the fusion peptide in the spike protein, which plays roles in virion adsorption and fusion. Mutation of the S2′ site of QX genotype (QX-type)...

(This article belongs to the Section Animal Viruses)
  • Article
  • Open Access
8 Citations
4,896 Views
15 Pages

Pathobiological and Genomic Characterization of a Cold-Adapted Infectious Bronchitis Virus (BP-caKII)

  • Seung-Min Hong,
  • Se-Hee An,
  • Chung-Young Lee,
  • Chang-Seon Song and ,
  • Kang-Seuk Choi,
  • Jae-Hong Kim and
  • Hyuk-Joon Kwon
  • + 2 authors+ 0 author

19 November 2018

We established a cold-adapted infectious bronchitis virus (BP-caKII) by passaging a field virus through specific pathogen-free embryonated eggs 20 times at 32 °C. We characterized its growth kinetics and pathogenicity in embryonated eggs, and its...

(This article belongs to the Special Issue Animal Models for Viral Diseases)
  • Review
  • Open Access
62 Citations
13,931 Views
22 Pages

Infectious Bronchitis Virus (Gammacoronavirus) in Poultry Farming: Vaccination, Immune Response and Measures for Mitigation

  • Md. Safiul Alam Bhuiyan,
  • Zarina Amin,
  • Kenneth Francis Rodrigues,
  • Suryani Saallah and ,
  • Sharifudin Md. Shaarani,
  • Subir Sarker and
  • Shafiquzzaman Siddiquee
  • + 2 authors+ 0 author

12 November 2021

Infectious bronchitis virus (IBV) poses significant financial and biosecurity challenges to the commercial poultry farming industry. IBV is the causative agent of multi-systemic infection in the respiratory, reproductive and renal systems, which is s...

(This article belongs to the Section Veterinary Microbiology, Parasitology and Immunology)
  • Article
  • Open Access
11 Citations
3,968 Views
12 Pages

Molecular Biology and Pathological Process of an Infectious Bronchitis Virus with Enteric Tropism in Commercial Broilers

  • Ana P. da Silva,
  • Ruediger Hauck,
  • Sabrina R. C. Nociti,
  • Colin Kern and ,
  • H. L. Shivaprasad,
  • Huaijun Zhou and
  • Rodrigo A. Gallardo
  • + 2 authors+ 0 author

28 July 2021

Infectious bronchitis virus (IBV) induces respiratory and urogenital disease in chickens. Although IBV replicates in the gastrointestinal tract, enteric lesions are uncommon. We have reported a case of runting-stunting syndrome in commercial broilers...

(This article belongs to the Special Issue Avian Respiratory Viruses, Volume II)
  • Article
  • Open Access
36 Citations
6,245 Views
13 Pages

Construction and Immunogenicity of Novel Chimeric Virus-Like Particles Bearing Antigens of Infectious Bronchitis Virus and Newcastle Disease Virus

  • Xuan Wu,
  • Xiwen Zhai,
  • Yan Lai,
  • Lei Zuo and ,
  • Yu Zhang,
  • Xueran Mei,
  • Rong Xiang,
  • Zhuangzhuang Kang,
  • Long Zhou and
  • Hongning Wang
  • + 5 authors+ 0 author

13 March 2019

Infectious bronchitis virus (IBV) and Newcastle disease virus (NDV) are two poultry pathogens seriously affecting the poultry industry. Here, IBV S1 and the ectodomain of NDV F proteins were separately linked with the trans-membrane and carboxy-termi...

(This article belongs to the Section Animal Viruses)
  • Article
  • Open Access
11 Citations
4,521 Views
13 Pages

Genetic and Pathogenic Characterization of QX(GI-19)-Recombinant Infectious Bronchitis Viruses in South Korea

  • So-Youn Youn,
  • Ji-Youn Lee,
  • You-Chan Bae,
  • Yong-Kuk Kwon and
  • Hye-Ryoung Kim

17 June 2021

Infectious bronchitis viruses (IBVs) are evolving continuously via genetic drift and genetic recombination, making disease prevention and control difficult. In this study, we undertook genetic and pathogenic characterization of recombinant IBVs isola...

(This article belongs to the Special Issue Avian Respiratory Viruses, Volume II)
  • Article
  • Open Access
13 Citations
3,248 Views
12 Pages

Origin of New Lineages by Recombination and Mutation in Avian Infectious Bronchitis Virus from South America

  • Ana Marandino,
  • Ariel Vagnozzi,
  • Gonzalo Tomás,
  • Claudia Techera and ,
  • Rocío Gerez,
  • Martín Hernández,
  • Joaquín Williman,
  • Mauricio Realpe,
  • Gonzalo Greif and
  • Ruben Pérez
  • + 6 authors+ 1 author

21 September 2022

The gammacoronavirus avian infectious bronchitis virus (IBV) is a highly contagious respiratory pathogen of primary economic importance to the global poultry industry. Two IBV lineages (GI-11 and GI-16) have been widely circulating for decades in Sou...

(This article belongs to the Special Issue Infectious Bronchitis Virus)
  • Article
  • Open Access
7 Citations
2,880 Views
12 Pages

Detection and Molecular Characterization of GI-1 and GI-23 Avian Infectious Bronchitis Virus in Broilers Indicate the Emergence of New Genotypes in Bolivia

  • Doris Villanueva-Pérez,
  • Luis Tataje-Lavanda,
  • Angela Montalván-Avalos,
  • Diego Paredes-Inofuente and ,
  • Suly Montoya-Ortiz,
  • Gisela Isasi-Rivas,
  • María F. Fernández,
  • Manolo Fernández-Sánchez and
  • Manolo Fernández-Díaz
  • + 4 authors+ 0 author

14 September 2024

Infectious Bronchitis Virus (IBV) is a major threat to the poultry industry worldwide, causing significant economic losses. While the virus’s genetic structure is well understood, the specific strains circulating in Bolivia have remained unchar...

(This article belongs to the Section Animal Viruses)

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