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Search Results (5,939)

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24 pages, 2997 KB  
Article
A Controllability-Based Reliability Framework for Mechanical Systems with Scenario-Driven Performance Evaluation
by Daniel Osezua Aikhuele and Shahryar Sorooshian
Appl. Syst. Innov. 2026, 9(4), 72; https://doi.org/10.3390/asi9040072 (registering DOI) - 27 Mar 2026
Abstract
In classical reliability engineering, failure is a probabilistic structural failure based on lifetime distributions of Weibull models. However, in the control-critical mechanical systems, it is possible that functional failure of the system happens before material failure occurs as a result of control power [...] Read more.
In classical reliability engineering, failure is a probabilistic structural failure based on lifetime distributions of Weibull models. However, in the control-critical mechanical systems, it is possible that functional failure of the system happens before material failure occurs as a result of control power loss. This paper proposes a Controllability–Reliability Coupling (CRC) model, which redefines the concept of reliability as the stabilizability in the face of progressive degradation. The actuators’ deterioration is modeled using the time-varying input effectiveness factor α(t), and the actuator is said to be in failure when the minimum singular value of the finite-horizon controllability Gramian becomes less than a stabilizability threshold ε. The performance of the simulation indicates that the functional failure is a precursor of structural failure in several degradation conditions. A baseline comparison shows that the CRC metric forecasts loss of controllability at TCRC=17.0 s, but the classical Weibull reliability never attains the structural failure threshold even in the time horizon of 20 s. The system retains margins of Lyapunov stability and H infinity robustness are not lost, and it is still stable and attenuates disturbances even when control authority is lost. In practical degradation scenarios, the forecasted CRC failure times are 21.5 s (linear wear), 13.1 s (accelerated fatigue), 23.7 s (intermittent faults), and 24.4 s (shock damage), whereas maintenance recovery abated functional failure completely. In a case study of an industrial robotic joint, at 27.0 s, functional collapse occurred, and at the same time, structural reliability was still above the failure threshold. The findings support the hypothesis that structural survival and functional controllability are distinct concepts. The proposed CRC framework is an approach to control-conscious reliability measure, which can detect early failures and offer proactive maintenance advice in the context of a cyber–physical system. Full article
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44 pages, 11387 KB  
Article
Integrated Theoretical Modeling and MASTA-Based Parametric Simulation for Contact Mechanics, Wear Behavior, of Critical Bearings in RV Reducers
by Weichen Kong, Xuan Li, Gaocheng Qian and Jiaqing Huang
Lubricants 2026, 14(4), 141; https://doi.org/10.3390/lubricants14040141 - 27 Mar 2026
Abstract
RV reducers are vital components in industrial robots and precision equipment, where the fatigue life of the crank arm and support bearings critically influences the overall system longevity. This study presents a comprehensive performance evaluation, with a specific focus on contact mechanics and [...] Read more.
RV reducers are vital components in industrial robots and precision equipment, where the fatigue life of the crank arm and support bearings critically influences the overall system longevity. This study presents a comprehensive performance evaluation, with a specific focus on contact mechanics and wear analysis of these critical bearings. A theoretical mathematical model for force analysis is established based on static mechanics, which is further extended to incorporate wear depth prediction based on contact pressure and sliding velocity. To validate this model and investigate bearing behavior in detail, a high-fidelity parametric simulation model is developed using MASTA software. The simulation results, encompassing contact stress, shear stress, and wear patterns, demonstrate good correlation with the predictions from the theoretical mathematical model, effectively verifying its accuracy for performance and life assessment. The systematic analysis confirms that both the investigated tapered roller and needle roller bearings meet the design requirements. This integrated approach of theoretical modeling, which includes wear analysis, and software simulation provides a reliable methodology for assessing bearing performance and fatigue life, offering significant value for the design optimization and reliability enhancement of RV reducers. Full article
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29 pages, 5997 KB  
Article
Study on Mechanical and Fatigue Behavior of Concrete Beams Prestressed with High Strength Aluminum Alloy Bars
by Jiahua Zhao, Zhaoqun Chang, Xiangzhi Peng, Pingze Peng, Meng Han and Boquan Liu
Buildings 2026, 16(7), 1339; https://doi.org/10.3390/buildings16071339 - 27 Mar 2026
Abstract
The corrosion of prestressed tendons in concrete structures remains a major durability concern, especially for post-tensioned members exposed to aggressive environments. High-strength aluminum alloy (AA) bars exhibit favorable characteristics such as corrosion resistance, low density, and high ductility and may therefore provide an [...] Read more.
The corrosion of prestressed tendons in concrete structures remains a major durability concern, especially for post-tensioned members exposed to aggressive environments. High-strength aluminum alloy (AA) bars exhibit favorable characteristics such as corrosion resistance, low density, and high ductility and may therefore provide an alternative or supplementary prestressing material in durability-oriented structural design. In this study, a bonded post-tensioned T-shaped concrete beam with hybrid prestressing combining prestressed steel (PS) strands and 7075 AA bars was investigated. A refined finite element model was developed by considering the bond-slip relationship between the AA tendons and grout inside corrugated tubes. The flexural behavior of the beam was analyzed through a combination of finite element simulation and sectional theoretical analysis. In addition, a fatigue-life assessment framework was established based on vehicle fatigue loads and material fatigue constitutive models, and the fatigue performance of the proposed hybrid beams was compared with that of conventional prestressed concrete beams. The theoretical predictions agreed reasonably well with the numerical results. Results indicated that partial replacement of PS strands with corrosion-resistant AA bars could alter the governing fatigue failure mode and improve the fatigue durability of prestressed beams under corrosive conditions. These findings highlight the potential of hybrid AA–PS prestressing as a durability-oriented strategy for concrete beams in corrosive environments. Full article
(This article belongs to the Topic Low-Carbon Materials and Green Construction)
16 pages, 3957 KB  
Article
Performance Assessment and Field Deployment of Carbon-Fiber-Reinforced Polymer (CFRP) Cables for Infrastructure Applications
by Sung-Jin Lee, Jongeok Lee and Woo-Tai Jung
Polymers 2026, 18(7), 811; https://doi.org/10.3390/polym18070811 - 26 Mar 2026
Abstract
Carbon-fiber-reinforced polymer (CFRP) cables have emerged as promising alternatives to conventional prestressing tendons because of their high tensile strength, excellent corrosion resistance, and low self-weight. Their use is particularly advantageous in infrastructure exposed to aggressive environments, such as chloride-induced corrosion, where improved durability [...] Read more.
Carbon-fiber-reinforced polymer (CFRP) cables have emerged as promising alternatives to conventional prestressing tendons because of their high tensile strength, excellent corrosion resistance, and low self-weight. Their use is particularly advantageous in infrastructure exposed to aggressive environments, such as chloride-induced corrosion, where improved durability and reduced maintenance are critically required. In this study, a 10 mm diameter round-bar-type CFRP cable was developed using a pultrusion process, and its applicability to structural systems was comprehensively evaluated through material testing and field implementation. Mechanical performance was assessed through tensile, relaxation, and fatigue tests. The developed CFRP cable exhibited an average tensile strength of 3019 MPa and an elastic modulus of 176.9 GPa, demonstrating mechanical properties comparable to or better than those of conventional prestressing tendons. The final relaxation ratio was measured as 2.25%, satisfying the low-relaxation criterion specified in KS D 7002. In the fatigue test, the cable sustained 2,000,000 loading cycles under a stress range corresponding to 60–66% of the ultimate tensile strength without fracture or significant stiffness degradation, confirming its excellent fatigue durability. In addition, the developed CFRP cable was implemented in a cable-net structure to verify its constructability and structural applicability in practice. The field application confirmed that the lightweight CFRP cable enabled convenient transportation and installation, while stable prestress introduction was achieved using the same tensioning procedure as that for conventional steel cable systems. The results demonstrate the integrated feasibility of the developed CFRP cable in terms of both material performance and practical structural application. This study provides experimental evidence supporting the structural use of CFRP tendons and offers a technical basis for the future development of design provisions and broader infrastructure applications. Full article
(This article belongs to the Section Polymer Applications)
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27 pages, 3627 KB  
Article
Optimizing Session Frequency in EEG Biofeedback: A Comparative Study of Protocol Dynamics and Neuromuscular Adaptation in Elite Judo Athletes
by Alicja Markiel, Dariusz Skalski, Kinga Łosińska, Marcin Żak and Adam Maszczyk
Sensors 2026, 26(7), 2077; https://doi.org/10.3390/s26072077 - 26 Mar 2026
Abstract
Background: The optimal frequency of EEG biofeedback sessions for elite athletes remains unclear, despite growing adoption of neurofeedback in high-performance sport. Methods: This randomized, controlled study compared three EEG biofeedback protocols (daily, every-other-day, every-third-day) in 24 national-level male judo athletes stratified into three [...] Read more.
Background: The optimal frequency of EEG biofeedback sessions for elite athletes remains unclear, despite growing adoption of neurofeedback in high-performance sport. Methods: This randomized, controlled study compared three EEG biofeedback protocols (daily, every-other-day, every-third-day) in 24 national-level male judo athletes stratified into three phenotypic groups. Each protocol comprised 15 standardized sessions. Pre- and post-intervention assessments included functional indices (strength, power) and neurophysiological measures (Frontal Alpha Index, EMG amplitude/RMS, corrected strength sum). Biosensor performance was validated via signal quality metrics. Results: Daily EEG biofeedback produced superior improvements in strength, FAI, and fatigue resistance. Although LRG showed the largest pre–post RMS increase (+17.44 μV vs. +16.54 μV in HRG), HRG maintained the highest post-intervention RMS values and best fatigue resistance (MF_drop = −2.15 Hz). Significant group × time interactions were observed for FAI (p = 0.027) and RMS (p = 0.019). Every-other-day protocols yielded moderate gains, while every-third-day protocols produced minimal or maladaptive EMG–load dynamics. A robust dose–response relationship was evident. Conclusions: Session frequency is critical for optimizing neurofeedback interventions in elite athletes. Daily EEG biofeedback confers superior adaptation compared to less frequent dosing. Full article
(This article belongs to the Special Issue Machine Learning in Biomedical Signal Processing)
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19 pages, 11241 KB  
Article
Data-Driven Health Monitoring of Construction Materials Based on Time Series Analysis of Crack Propagation Sensors
by Paulina Kurnyta-Mazurek and Artur Kurnyta
Materials 2026, 19(7), 1317; https://doi.org/10.3390/ma19071317 - 26 Mar 2026
Abstract
The paper investigates the applicability of time series models for processing data obtained from a customized crack-propagation sensor. Because the sensor records a variable and noise-affected waveform, the study focuses on models capable of forecasting signals composed of both trend and stochastic components. [...] Read more.
The paper investigates the applicability of time series models for processing data obtained from a customized crack-propagation sensor. Because the sensor records a variable and noise-affected waveform, the study focuses on models capable of forecasting signals composed of both trend and stochastic components. Adaptive, analytical, and autoregressive approaches were examined, with particular attention to their suitability for short, non-stationary sequences typical of fatigue-related measurements. Based on the statistical characteristics of the sensor output during crack growth, the ARIMA model was selected for further analysis and algorithm development. The forecasting performance of ARIMA was evaluated for different parameter configurations by comparing the range and variability of the base and predicted data. Initial tests using first-order parameters produced unsatisfactory results, with high variance observed in both raw and modeled signals. Therefore, model parameters were optimized using the aicbic function, and the analyses were repeated. For the selected datasets, variance reduction by 3–4 orders of magnitude was achieved, demonstrating a substantial improvement in prediction stability. The presented results confirm that the proposed methodology is effective for processing complex sensor signals and highlight the broader significance of applying statistically grounded time series models in structural health monitoring. The study introduces an innovative framework for evaluating fatigue-related sensor data and establishes a reliable baseline for future predictive methods. Full article
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36 pages, 1048 KB  
Review
Patient-Specific 3D-Printed Porous Metal Implants in Orthopedics: A Narrative Review of Current Applications and Future Prospects
by Connor P. McCloskey, Anoop Sunkara, Siddhartha Kalala, Jack T. Peterson, Michael O. Sohn, Austin R. Chen, Arun K. Movva and Albert T. Anastasio
Appl. Sci. 2026, 16(7), 3192; https://doi.org/10.3390/app16073192 - 26 Mar 2026
Abstract
Atypical joint spaces, such as those encountered in complex segmental bone loss and large structural defects, remain challenging to manage with conventional implants within divisions across orthopedics, including arthroplasty, tumor reconstruction, trauma, and spine. Additive manufacturing advances have made patient-specific implants a possibility, [...] Read more.
Atypical joint spaces, such as those encountered in complex segmental bone loss and large structural defects, remain challenging to manage with conventional implants within divisions across orthopedics, including arthroplasty, tumor reconstruction, trauma, and spine. Additive manufacturing advances have made patient-specific implants a possibility, and this promising solution has enabled the creation of implants with customized geometry and controlled surface porosity to enhance osseointegration, reduce rejection rates, optimize biomechanics, and promote longevity. Despite its potential, patient-specific implants are still eclipsed in use by conventional, “off-the-shelf” implants due to their lower cost, documented long-term durability, insurance coverage, and the strength of available clinical evidence supporting their use. This narrative review summarizes current materials and manufacturing approaches for additively manufactured metal porous implants, including imaging and design workflows, lattice and pore architecture, and how the printing process influences implant stiffness, fatigue strength, surface roughness, and porosity. We also discuss the experimental and preclinical data on mechanical performance, fatigue resistance, and osseointegration for new developments in the field. Emerging trends such as material innovation, streamlined digital planning-to-implant workflows, 4D printing and other advanced additive manufacturing concepts, and cost-reduction efforts are examined in the context of clinical practicality. In this review, the integration of engineering principles with early clinical outcomes will provide orthopedic surgeons with a realistic understanding of the benefits and limitations of the future utilization of additive manufacturing in clinical practice. Full article
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15 pages, 260 KB  
Article
Intraday and Interday Reliability of Maximal and Explosive Handgrip Force–Time Metrics Using the Kinvent K-Grip Handheld Dynamometer
by Ivan Curovic, Milan Markovic, Lazar Toskic, Jill Alexander and Damian J. Harper
Muscles 2026, 5(2), 24; https://doi.org/10.3390/muscles5020024 - 25 Mar 2026
Abstract
(1) Background: Handgrip strength (HGS) is a widely used indicator of neuromuscular function, with predictive values for health and performance outcomes. The aim of this study was to evaluate the intraday and interday reliability of maximal and explosive handgrip force–time metrics using the [...] Read more.
(1) Background: Handgrip strength (HGS) is a widely used indicator of neuromuscular function, with predictive values for health and performance outcomes. The aim of this study was to evaluate the intraday and interday reliability of maximal and explosive handgrip force–time metrics using the Kinvent K-Grip handheld dynamometer. (2) Methods: Thirty-four participants performed three maximal voluntary isometric contractions per hand across two testing days. Force–time data were analysed for peak force (PF), mean force (MF), peak rate of force development (RFD), time-specific RFD, impulse, and forces at fixed time points. Reliability was assessed using intraclass correlation coefficients (ICCs), standard error of measurement (SEM), minimal detectable change (MDC), and coefficient of variation (CV%). (3) Results: The device demonstrated excellent relative and absolute reliability for PF and MF across both days (ICC > 0.97; CV < 6%; MDC ≈ 5 kg). Later-phase explosive metrics (F250 and Imp200) showed good-to-excellent relative reliability (ICC = 0.88-0.99; CV = 4–14%), although with variable absolute reliability (MDC F250 ≈ 4–8 kg, MDC Imp200 ≈ 1 kg·s). For early-phase metrics, relative reliability was only moderate to good (ICC = 0.67–0.88) and characterised by a high degree of variability (CV = 15–22%). (4) Conclusions: The K-Grip handheld dynamometer is a reliable tool for cross-sectional assessments and for tracking larger maximal strength and later-phase force improvements at fixed time points. Early-phase explosive metrics are less suitable for monitoring intervention effects due to high measurement error and fatigue sensitivity. Full article
26 pages, 9393 KB  
Article
Hydrodynamic Simulations of a 2MW Offshore Solar Farm with Floating Breakwater Protection
by Tim Bunnik, Naman Baderiya and Joep van der Zanden
Energies 2026, 19(7), 1609; https://doi.org/10.3390/en19071609 - 25 Mar 2026
Viewed by 39
Abstract
Following successful applications in inland water bodies, floating photovoltaics (FPV) developers are now targeting offshore sites. This advancement requires numerical tools that can quantify the hydrodynamic performance of large-scale FPV farms. The existing wave-diffraction solver DIFFRAC was extended to simulate the response of [...] Read more.
Following successful applications in inland water bodies, floating photovoltaics (FPV) developers are now targeting offshore sites. This advancement requires numerical tools that can quantify the hydrodynamic performance of large-scale FPV farms. The existing wave-diffraction solver DIFFRAC was extended to simulate the response of a large number of interconnected floating objects on a supercomputer. The applicability is demonstrated by simulating a 2 MWp offshore solar farm, consisting of 3660 FPV modules moored inside a protective ring of 32 interconnected floating breakwaters (FBWs). The FPV motions and loads on FPV connectors in regular and irregular waves are compared to a reference case without FBW protection. Results show an average reduction in axial FPV connector loads in the setup with FBW ring, but local load enhancements occur due to dynamic amplifications of horizontal FPV module motions. Vertical loads and overturning moments onto FPV connectors are globally reduced by up to 50% in steep irregular seas but are locally enhanced due to standing waves that develop inside the ring. The insights of the hydrodynamic behaviour lead to recommendations for improving the farm configuration to further reduce fatigue and survival loads onto FPV modules and connectors. Full article
(This article belongs to the Special Issue Floating PV Systems On and Offshore: 2nd Edition)
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12 pages, 1274 KB  
Article
The Impact of Mental Fatigue on Decision-Making Abilities, Visual Search Strategies, and Simple Reaction Time in Handball Players: A Randomized Crossover Study
by Jeongwon Kim, Dongwon Yook and Sojin Han
Sports 2026, 14(4), 128; https://doi.org/10.3390/sports14040128 - 25 Mar 2026
Viewed by 52
Abstract
This study investigated the effects of mental fatigue induced by social media (SM) use and the Stroop task on decision-making, visual search strategies, and reaction time in elite collegiate handball players (n = 16). Using a randomized, counterbalanced cross-over design, both interventions [...] Read more.
This study investigated the effects of mental fatigue induced by social media (SM) use and the Stroop task on decision-making, visual search strategies, and reaction time in elite collegiate handball players (n = 16). Using a randomized, counterbalanced cross-over design, both interventions successfully induced subjective mental fatigue, as confirmed by visual analog scale (VAS) ratings. Decision-making accuracy and reaction time improved following the Stroop task, likely due to compensatory mechanisms described in the regulatory-control model. In the SM condition, no significant impairments were observed in decision-making performance; however, visual reaction time was specifically delayed, while auditory reaction time remained unaffected, suggesting modality-specific effects of SM-induced fatigue. Visual search behaviors remained largely stable, with only marginal alterations observed in non-task-relevant areas following the Stroop task. These findings highlight the cognitive resilience and adaptive control mechanisms of elite athletes in maintaining and, in some cases, enhancing performance under mental fatigue. Future studies should integrate neurophysiological indices and manipulate motivational factors to further clarify these mechanisms across diverse athletic populations. Full article
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16 pages, 2597 KB  
Article
Impact of De-Icing Coatings and Ice Accretion on Wind Turbine Performance
by Guangcheng Gu, Pei Li, Danqing Jiang, Zhean Bao, Jie Wang, Zhiliang Xue and Yonggang Zhou
Energies 2026, 19(6), 1587; https://doi.org/10.3390/en19061587 - 23 Mar 2026
Viewed by 136
Abstract
Wind power has experienced rapid development due to its renewable advantages. To address the performance degradation of wind turbines caused by icing in alpine regions, this study integrates field testing and numerical simulation to analyze three key aspects for a 1.5 MW turbine: [...] Read more.
Wind power has experienced rapid development due to its renewable advantages. To address the performance degradation of wind turbines caused by icing in alpine regions, this study integrates field testing and numerical simulation to analyze three key aspects for a 1.5 MW turbine: the underlying mechanism of icing impact, the effect of a de-icing coating on performance during ice-free operation, and the coating’s efficacy under active icing conditions. Results show that ice accretion causes a 25% power loss, induces severe flow separation and vortex shedding, and shifts the separation point forward to 15% chord length. Under ice-free conditions at an average wind speed of 8.3 m/s, the de-icing coating introduces a negligible power deviation of only 0.4%. In extreme cold, ice thickness on the coated blade section was measured at just 4.86 cm. The research demonstrates that de-icing the outer 10 m blade tip section substantially improves performance and confirms that the coating has a minimal aerodynamic footprint during normal operation while providing effective ice mitigation. These findings offer a scientific foundation for optimizing de-icing techniques and support the broader application of such coatings for wind turbines in cold climates. Full article
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26 pages, 1601 KB  
Article
Performance Control and Mechanism Analysis of DCLR-Based Composite High-Modulus Asphalt Based on Synergistic Modification Effect
by Bin Xu, Xinjie Yu, Aodong Gao, Guanjun Bu and Kaiji Lu
Materials 2026, 19(6), 1268; https://doi.org/10.3390/ma19061268 - 23 Mar 2026
Viewed by 150
Abstract
To address the prominent problem of early rutting distress in asphalt pavements under heavy-load traffic in China, this study proposes a composite modifier consisting of direct coal liquefaction residue (DCLR), styrene–butadiene–styrene block copolymer (SBS), and styrene–butadiene rubber (SBR). The preparation process and formula [...] Read more.
To address the prominent problem of early rutting distress in asphalt pavements under heavy-load traffic in China, this study proposes a composite modifier consisting of direct coal liquefaction residue (DCLR), styrene–butadiene–styrene block copolymer (SBS), and styrene–butadiene rubber (SBR). The preparation process and formula were optimized through single-factor experiments and orthogonal tests. Systematic investigations were conducted on its conventional performance, water damage resistance, aging resistance, fatigue performance, rheological properties, and microscopic mechanism, with comparisons made against base asphalt, single DCLR-modified asphalt, SBS-modified asphalt, and SBS/SBR-modified asphalt. The results indicate that the optimal preparation process for the novel composite high-modulus modified asphalt is as follows: DCLR particle size of 0.3 mm, addition in molten state, shear temperature of 170 °C, shear rate of 5000 r·min−1, shear time of 50 min. The optimal formula is 10% DCLR + 3% SBS + 2% SBR + 3% compatibilizer, with the addition sequence of “DCLR → SBS + compatibilizer → SBR”. This asphalt exhibits a softening point of 77.8 ± 2.1 °C, a Brookfield viscosity at 135 °C of 1.928 ± 0.105 Pa·s, and a grading of 5 for adhesion to aggregates; the rutting factor at 64 °C reaches 10.8 ± 0.9 kPa (6.43 times that of the base asphalt), the creep stiffness at −12 °C is 136 ± 12.5 MPa, and the low-temperature limit temperature is −17 °C; the freeze–thaw splitting strength ratio (TSR) is 94.6 ± 1.8%, and both aging resistance and water damage resistance are significantly superior to those of the control group asphalts (p < 0.05). The novel composite high-modulus modified asphalt showed improved overall laboratory performance and may be suitable for heavy-load traffic and complex climatic conditions, however, field validation is needed. Full article
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16 pages, 1424 KB  
Review
Structural and Metabolic Remodeling of Skeletal Muscle in Heart Failure with Reduced Ejection Fraction: A Review: Beyond the Failing Heart
by Mamata Chaudhari, Jamila Makhloufi, Benjamin Doelling, Raveena Kataria, Aruni Bhatnagar, Dinesh Kalra and Shahid Pervez Baba
Int. J. Mol. Sci. 2026, 27(6), 2886; https://doi.org/10.3390/ijms27062886 - 23 Mar 2026
Viewed by 129
Abstract
Heart failure (HF) with reduced ejection fraction is a systemic disorder that extends beyond cardiac dysfunction and involves peripheral organs, particularly skeletal muscle. Exercise intolerance and fatigue are the hallmark manifestations of HF that strongly predict morbidity and mortality. Accumulating evidence suggests that [...] Read more.
Heart failure (HF) with reduced ejection fraction is a systemic disorder that extends beyond cardiac dysfunction and involves peripheral organs, particularly skeletal muscle. Exercise intolerance and fatigue are the hallmark manifestations of HF that strongly predict morbidity and mortality. Accumulating evidence suggests that intrinsic skeletal muscle abnormalities are key contributors to exercise intolerance in HF. In HF, skeletal muscle undergoes metabolic remodeling characterized by shifts in fiber type composition, mitochondrial dysfunction, and increased oxidative stress. Mitochondrial dysfunction, characterized by decreased mitochondrial density, impaired biogenesis, and reduced respiratory capacity, further compromises skeletal muscle performance. These alterations impair adenosine triphosphate (ATP) generation via oxidative phosphorylation, forcing reliance on less efficient anaerobic glycolysis. The resulting metabolic shift exacerbates early lactate accumulation, muscle fatigue, and diminished exercise capacity. In parallel, an increase in oxidative and carbonyl stress, along with a decrease in antioxidant defenses as well as derangements in pathways that remove toxic lipid peroxidation, heightens oxidative and carbonyl stress perpetuating injury and establishing a vicious cycle of progressive muscle dysfunction. Thus, metabolic remodeling in skeletal muscle represents a central determinant of exercise intolerance in HF. While exercise training remains the most effective strategy to restore skeletal muscle health and exercise tolerance, emerging therapies offer novel avenues for intervention. Future research should focus on elucidating the molecular mechanisms underlying skeletal muscle dysfunction and developing therapies that restore metabolic integrity and functional capacity in HF. Full article
(This article belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
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25 pages, 3190 KB  
Review
High-Temperature Carburization of Gear Steels: Grain Size Regulation, Microstructural Evolution, and Surface Performance Enhancement
by Xiangyu Zhang, Yuxian Cao, Yu Zhang, Dong Pan, Kunyu Wang, Zhihui Li and Leilei Li
Coatings 2026, 16(3), 386; https://doi.org/10.3390/coatings16030386 - 21 Mar 2026
Viewed by 217
Abstract
High-temperature carburization (HTC, 950–1050 °C) has emerged as a pivotal low-carbon, energy-efficient manufacturing technology for gear steels, accelerating carbon diffusion for reducing processing cycles by over 60% while achieving significant energy savings and emission reductions. However, the inherent contradiction between HTC efficiency and [...] Read more.
High-temperature carburization (HTC, 950–1050 °C) has emerged as a pivotal low-carbon, energy-efficient manufacturing technology for gear steels, accelerating carbon diffusion for reducing processing cycles by over 60% while achieving significant energy savings and emission reductions. However, the inherent contradiction between HTC efficiency and microstructural stability, specifically austenite grain coarsening, severely degrades mechanical properties (e.g., strength, toughness, fatigue resistance) and limits widespread application. This review systematically synthesizes recent advances in austenite grain size regulation during HTC of gear steels, focusing on the core scientific framework of “grain coarsening mechanism—regulation strategy—performance enhancement”. It elaborates on thermodynamic and kinetic mechanisms of austenite grain growth, ripening behavior of microalloying precipitates (Nb(C,N), Ti(C,N), AlN, etc.), and their synergistic grain-refining effects. Comprehensive coverage of regulatory strategies (microalloying design, pretreatment technologies, process optimization, and integrated regulation) and characterization techniques is provided, along with a quantitative correlation between grain size, microstructure, and surface performance (wear resistance, corrosion resistance, and fatigue life). Numerical simulation and predictive models (empirical, theoretical, multiphysics coupling, machine learning-based) are critically analyzed, and current challenges (temperature-grain stability trade-off, multifactor synergy understanding, industrial scalability) and future research directions (advanced microalloying systems, intelligent process optimization, cross-scale modeling, green technology integration) are proposed. This review aims to provide theoretical guidance and technical support for optimizing the HTC performance of gear steels, catering to the demands of high-power-density transmission systems in automotive, aerospace, and heavy machinery industries. Full article
(This article belongs to the Special Issue Surface Treatment and Mechanical Properties of Metallic Materials)
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11 pages, 891 KB  
Article
The Effect of a Novel Achilles Brace on Concentric and Eccentric Achilles Tendon Loading During Tendon Tear Mechanisms
by Roni Gottlieb, Shai Greenberg, Asaf Shalom and Julio Calleja Gonzalez
Life 2026, 16(3), 524; https://doi.org/10.3390/life16030524 - 21 Mar 2026
Viewed by 159
Abstract
(1) Achilles tendon rupture is one of the most severe lower-limb injuries, frequently occurring during movements involving maximal dorsiflexion with the knee at near-full extension. Preventive strategies are crucial, particularly for athletes engaged in high-risk sports such as basketball. (2) In this work, [...] Read more.
(1) Achilles tendon rupture is one of the most severe lower-limb injuries, frequently occurring during movements involving maximal dorsiflexion with the knee at near-full extension. Preventive strategies are crucial, particularly for athletes engaged in high-risk sports such as basketball. (2) In this work, we examined the effect of a novel Achilles brace on Achilles tendon loading during concentric and eccentric mechanisms associated with tendon rupture. (3) Twenty-eight young basketball players performed tests under two conditions: with the adaptive brace and without it (control). Participants were divided into two groups (n = 14 in both). The first group assessed concentric Achilles loading by performing three plantar-flexor strength tests in three different joint configurations: maximal dorsiflexion with the knee flexed (FKF); injury mechanism position—full plantar flexion with the knee extended (FKE); and neutral ankle position with the knee extended (NKE). The number of maximal heel-raise repetitions performed before onset of fatigue was recorded. The second group assessed eccentric tendon loading by performing single-leg forced maximal-velocity dorsiflexion with the knee extended. In all tests, the time between maximal plantar flexion and maximal dorsiflexion, as well as the ankle range of motion, was analyzed using 2D video. Paired t-tests were used to compare braced and control conditions. In all tests, the ankle range of motion (ROM) did not differ significantly between brace and control conditions. Wearing the brace significantly improved plantar-flexor muscle strength only in the FKE test (31 ± 1.3 repetitions with brace vs. 21 ± 1.3 in control, p < 0.05). No significant differences were found for the FKF (27 ± 1.3 vs. 25 ± 1.3) or NKE (25 ± 1.3 vs. 24 ± 1.3) positions. During drop eccentric loading, wearing the brace resulted in a significantly slower transition time from plantar flexion to dorsiflexion (460 ± 60 ms with brace vs. 320 ± 30 ms in control, p < 0.001). (4) In brief, the novel Achilles brace was found to significantly reduces Achilles tendon load during both concentric and eccentric activities, but only in high-risk joint positions. These findings suggest that the brace provides mechanical protection, and may reduce the risk of Achilles tendon rupture, in athletes exposed to high tendon stress. Full article
(This article belongs to the Section Physiology and Pathology)
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