Search Results (16,110)

Accurate staging of bladder cancer is critical for guiding clinical management, particularly the distinction between non–muscle-invasive (T1) and muscle-invasive (T2–T4) disease. Although MRI offers superior soft-tissue contrast, image interpretation remains operator-dependent and subject to inter-observer variability. This study proposes an automated deep learning framework for MRI-based bladder cancer staging to support standardized radiological interpretation. A sequential AI-based pipeline was developed, integrating hybrid tumor segmentation using YOLOv11 for lesion detection and DeepLabV3 for boundary refinement, followed by three deep learning classifiers (VGG19, ResNet50, and Vision Transformer) for MRI-based stage prediction. A total of 416 T2-weighted MRI images with radiology-derived stage labels (T1–T4) were included, with data augmentation applied during training. Model performance was evaluated using accuracy, precision, recall, F1-score, and multi-class AUC. Performance uncertainty was characterized using patient-level bootstrap confidence intervals under a fixed training and evaluation pipeline. All evaluated models demonstrated high and broadly comparable discriminative performance for MRI-based bladder cancer staging within the present dataset, with high point estimates of accuracy and AUC, particularly for differentiating non–muscle-invasive from muscle-invasive disease. Calibration analysis characterized the probabilistic behavior of predicted stage probabilities under the current experimental setting. The proposed framework demonstrates the feasibility of automated MRI-based bladder cancer staging derived from radiological reference labels and supports the potential of deep learning for standardizing and reproducing MRI-based staging procedures. Rather than serving as an independent clinical decision-support system, the framework is intended as a methodological and workflow-oriented tool for automated staging consistency. Further validation using multi-center datasets, patient-level data splitting prior to augmentation, pathology-confirmed reference standards, and explainable AI techniques is required to establish generalizability and clinical relevance. Full article

The K-means clustering algorithm is widely applied in various clustering tasks due to its high computational efficiency and simple implementation. However, its performance significantly deteriorates when dealing with non-convex structures, fuzzy boundaries, or noisy data, as it relies on the assumption that clusters are spherical or linearly separable. To address these limitations, this paper proposes a Gaussian membership-driven fuzzy granular K-means clustering method. In this approach, multi-function Gaussian membership functions are used for fuzzy granulation at the single-feature level to generate fuzzy granules, while fuzzy granule vectors are constructed in the multi-feature space. A novel distance metric for fuzzy granules is defined along with operational rules, for which axiomatic proof is provided. This Gaussian-based granulation enables effective modeling of nonlinear separability in complex data structures, leading to the development of a new fuzzy granular K-means clustering framework. Experimental results on multiple public UCI datasets demonstrate that the proposed method significantly outperforms traditional K-means and other baseline methods in clustering tasks involving complex geometric data (e.g., circular and spiral structures), showing improved robustness and adaptability. This offers an effective solution for clustering data with intricate distributions. Full article

In this paper, a microwave metasurface sensor integrated with artificial intelligence (AI) for breast tumor detection is presented. The sensor’s sensitivity is estimated by analyzing shifts in magnitude and the phase of the reflection coefficient ($S_{11}$) obtained from normal and abnormal breast phantoms. The ($S_{11}$) responses of 137 anatomically realistic 3D numerical breast phantoms in standard classes, C1—mostly fatty, C2—scattered fibroglandular, C3—heterogeneously dense, and C4—extremely dense, incorporating different tumor sizes are used as input features. A custom neural network is developed to detect tumor presence using the recorded ($S_{11}$) responses. The model is trained with cross-entropy loss and the AdamW optimizer. The dataset is split into training (70%), validation (15%), and test (15%) sets. The model achieves 99% accuracy, with perfect precision, recall, and F1-score across individual classes. For paired class combinations, accuracies of 71% (C1 with C2) and 65% (C2 with C3) are obtained, while performance degrades to approximately 50% when all four classes are combined. The sensor is fabricated and experimentally validated using two physical breast phantoms, demonstrating reliable detection of a 10 mm tumor. These results highlight the effectiveness of combining microwave metasurface sensing and AI for breast tumor detection. Full article

Industrial Control Systems (ICSs) are critical infrastructure for maintaining social and economic stability, but they face increasing security threats that require robust anomaly detection mechanisms. Anomaly detection in ICS, based on sensor data, is essential for identifying abnormal behaviors caused by factors such as equipment failures, cyber-attacks, and operational mistakes. However, industrial time series data are often multimodal, noisy, and exhibit both short-term fluctuations and long-term dependencies, making them difficult to model effectively. Additionally, ICS data often contain high-frequency noise and complex periodic patterns, which traditional methods and standalone models, such as Long Short-Term Memory (LSTM), fail to capture effectively. To address these challenges, we propose a novel anomaly detection framework that leverages Gated Recurrent Units for short-term dynamics and PatchTST for long-term dependencies. The GRU module extracts dynamic short-term features, while PatchTST models long-term dependencies by segmenting the feature sequence processed by GRU into overlapping patches. Additionally, we innovatively introduce Frequency-Enhanced Channel Attention Module to capture frequency domain features, mitigating high-frequency noise and enhancing the model’s ability to detect long-term trends and periodic patterns. Experimental results on the SWaT and WADI datasets show that the proposed method achieves strong anomaly detection performance, attaining F1 scores of 0.929 and 0.865, respectively, which are superior to those of representative existing methods, demonstrating the effectiveness of the proposed design for robust anomaly detection in complex ICS environments. Full article

Large field-of-view (FOV) infrared imaging, widely utilized in applications including target detection and remote sensing, generates massive datasets that pose significant challenges for transmission and storage. To address this issue, we propose an efficient lossless compression method for large FOV infrared video. Our approach employs a hybrid prediction strategy within the transform domain. The video frames are first decomposed into low- and high-frequency components via the discrete wavelet transform. For the low-frequency subbands, an improved low-latency Multi-view High-Efficiency Video Coding (MV-HEVC) encoder is adopted, where the background reference frames are treated as one view to enable more accurate inter-frame prediction. For high-frequency components, pixel-wise clustered edge prediction is applied. Furthermore, the prediction residuals are reduced by optimal direction prediction, according to the principle of minimizing residual energy. Experimental results demonstrate that our method significantly outperforms mainstream video compression techniques. While maintaining compression performance comparable to MV-HEVC, the proposed method exhibits a 19.3-fold improvement in computational efficiency. Full article

Background: MicroRNAs (miRNAs) are an important class of non-coding RNAs that regulate gene expression by binding to target mRNAs and influencing cellular processes such as differentiation, proliferation, and apoptosis. Dysregulation in miRNA expression has been reported to be implicated in many human diseases, including cancer, cardiovascular, and neurodegenerative disorders. Identifying disease-related miRNAs is therefore essential for understanding disease mechanisms and supporting biomarker discovery, but time and cost of experimental validation are the main limitations. Methods: We present a graph-based learning framework that models the complex relationships between miRNAs, diseases, and related biological entities within a heterogeneous network. The model employs a message-passing neural architecture to learn structured embeddings from multiple node and edge types, integrating biological priors from curated resources. This network representation enables the inference of novel miRNA–disease associations, even in sparsely annotated regions of the network. The approach was trained and validated on a dataset benchmark using ten replicated experiments to ensure robustness. Results: The method achieved an average AUC–ROC of ~98%, outperforming previously reported computational approaches on the same dataset. Moreover, predictions were consistent across validation folds and robustness analyses were conducted to evaluate stability and highlight the most important information. Conclusions: Integrating heterogeneous biological information and representing it through graph neural network representation learning offers a powerful and generalizable way to predict relevant associations, including miRNA–disease, and provide a robust computational framework to support biomedical discovery and translational research. Full article

This study introduces a predictive model based on artificial neural networks (ANNs) for estimating the dynamic performance of commercially available sensible thermal energy storage (STES) systems. The model was trained and validated using high-resolution experimental data measured from two vertical cylindrical tanks (0.3 m³ each) including internal heat exchangers and operating under both heating and cooling modes. A comprehensive sensitivity analysis was conducted on 28 ANN architectures by varying the number of hidden neurons and input delays. The optimal configuration, designated as ANN5 (12 neurons, delay = 1), demonstrated superior accuracy in predicting temperature profiles and energy exchange. Validation against an independent dataset confirmed the model’s robustness, achieving normalized root mean square errors (NRMSEs) between 0.0022 and 0.0061 for the hot tank and between 0.0057 and 0.0283 for the cold tank. Energy prediction errors were within −3.87% for charging and 0.09% for discharging in heating mode, and 7.08% for charging and 0.13% discharging in cooling mode, respectively. These results highlight the potential of ANN-based approaches for real-time control, forecasting, and digital twin applications in STES systems. Full article

Noise remains a persistent limitation in coherent imaging systems, degrading image quality and hindering accurate interpretation in critical applications such as remote sensing, medical imaging, and non-destructive testing. This paper presents a physics-informed deep learning framework for effective image denoising under complex noise conditions. The proposed approach integrates nonlinear partial differential equations (PDEs), including the heat equation, diffusion models, MPMC, and the Zhichang Guo (ZG) method, into advanced neural network architectures such as ResUNet, UNet, U2Net, and Res2UNet. By embedding physical constraints directly into the training process, the framework couples data-driven learning with physics-based priors to enhance noise suppression and preserve structural details. Experimental evaluations across multiple datasets demonstrate that the proposed method consistently outperforms conventional denoising techniques, achieving higher PSNR, SSIM, ENL, and CNR values. These results confirm the effectiveness of combining physics-informed neural networks with deep architectures and highlight their potential for advanced image restoration in real-world, high-noise imaging scenarios. Full article

This paper introduces LLM4ATS , a framework integrating large language models, RAG, and closed-loop verification to automatically generate highly reliable automotive automated test scripts from natural language descriptions. Addressing the complex linguistic structure, strict rules, and strong dependency on the in-vehicle communication database inherent in ATS scripts, LLM4ATS innovatively employs fine-grained line-level generation and a rule-guided iterative refinement mechanism. The framework first enhances prompt context by retrieving relevant information from constructed syntax and case knowledge bases via RAG. Subsequently, each generated script line undergoes rigorous verification through a two-stage validator: initial syntax validation followed by semantic compliance checks against the communication database for signal paths and value domains. Any errors trigger structured feedback, driving iterative refinement by the large language model until fully compliant scripts are produced. This paper evaluated the framework’s effectiveness on real ATS datasets, testing models including GPT-3.5, GPT-4, Qwen2.5-7B, and Qwen2.5-72B-Instruct. Experimental results demonstrate that compared to zero-shot and few-shot baseline methods, the LLM4ATS framework significantly improves generation quality and pass rates across all models. Notably, the strongest GPT-4 model achieved a script pass rate of 91% with LLM4ATS, up from 42% in zero-shot mode, and validated functional effectiveness on a specified in-vehicle hardware platform (Chery Fengyun T28 dashboard). At the same time, expert manual evaluations confirmed the superior performance of the generated scripts in correctness, readability, and compliance with industry standards. Full article

Estimating 6D object pose from monocular RGB images remains a critical yet data-intensive challenge in computer vision. In this work, we propose a novel few-shot 6D pose estimation framework that explicitly decouples rotation and translation estimation, significantly reducing dependence on large-scale annotated real-world data. Our method employs a viewpoint encoder trained solely on synthetic data to generate a codebook for rotation retrieval, complemented by an in-plane rotation regression module. For translation, we adopt a geometry-aware regression network based on dense 2D–3D correspondences. Experimental results on LINEMOD, LM-O, and YCB-V datasets demonstrate that our approach achieves state-of-the-art performance (97.6%, 65.3%, and 65.9% ADD(-S), respectively), using only 600 real images per object—cutting real data requirements by 80% compared to typical fully-supervised 6D pose estimation methods. These findings highlight the effectiveness and generalization ability of our method under limited supervision. Full article

Background: Accurate and dependable brain tumor classification from magnetic resonance imaging (MRI) is essential for clinical decision support, yet remains challenging due to inter-dataset variability, heterogeneous tumor appearances, and limited generalization of many deep learning models. Existing studies often rely on single-dataset evaluation, insufficient statistical validation, or lack interpretability, which restricts their clinical reliability and real-world deployment. Methods: This study proposes a robust brain tumor classification framework based on the ConvNeXt Base architecture. The model is evaluated across three independent MRI datasets comprising four classes—glioma, meningioma, pituitary tumor, and no tumor. Performance is assessed using class-wise and aggregate metrics, including accuracy, precision, recall, F1-score, AUC, and Cohen’s Kappa. The experimental analysis is complemented by ablation studies, computational efficiency evaluation, and rigorous statistical validation using Friedman’s aligned ranks test, Holm and Wilcoxon post hoc tests, Kendall’s W, critical difference diagrams, and TOPSIS-based multi-criteria ranking. Model interpretability is examined using Grad-CAM++ and Gradient SHAP. Results: ConvNeXt Base consistently achieves near-perfect classification performance across all datasets, with accuracies exceeding 99.6% and AUC values approaching 1.0, while maintaining balanced class-wise behavior. Statistical analyses confirm that the observed performance gains over competing architectures are significant and reproducible. Efficiency results demonstrate favorable inference speed and resource usage, and explainability analyses show that predictions are driven by tumor-relevant regions. Conclusions: The results demonstrate that ConvNeXt Base provides a reliable, generalizable, and explainable solution for MRI-based brain tumor classification. Its strong diagnostic accuracy, statistical robustness, and computational efficiency support its suitability for integration into real-world clinical and diagnostic workflows. Full article

To address the challenge of defect detection in tempered glass panel production rising from sample scarcity, this paper proposes a few-shot detection methodology that integrates an enhanced Stable Diffusion model with Mask R-CNN. Specifically, the approach utilizes a Mask Encoder to optimize the Stable Diffusion architecture, employing the Structural Similarity Index Measure (SSIM) to evaluate sample quality. This process generates high-fidelity virtual samples to construct a hybrid dataset for training data augmentation. Furthermore, a resource isolation strategy is adopted to facilitate online detection using an improved semi-supervised Mask R-CNN framework. Experimental results demonstrate that the proposed scheme effectively resolves detection difficulties for eight defect types, including edge chipping and scratches. The method achieves an mAP50 of 81.5%, representing a nearly 47% improvement over baseline methods relying solely on real samples, thereby realizing high-precision and high-efficiency industrial defect detection. Full article

Precise identification of weeds at the maize seedling stage is pivotal for implementing Site-Specific Weed Management and minimizing herbicide environmental pollution. However, the performance of existing lightweight detectors is severely bottlenecked by unstructured field environments, characterized by the “green-on-green” spectral similarity between crops and weeds, diminutive seedling targets, and complex mutual occlusion of leaves. To address these challenges, this study proposes SLD-YOLO11, a topology-reconstructed lightweight detection model tailored for complex field environments. First, to mitigate the feature loss of tiny targets, a Lossless Downsampling Topology based on Space-to-Depth Convolution (SPD-Conv) is constructed, transforming spatial information into depth channels to preserve fine-grained features. Second, a Decomposed Large Kernel Attention (D-LKA) mechanism is designed to mimic the wide receptive field of human vision. By modeling long-range spatial dependencies with decomposed large-kernel attention, it enhances discrimination under severe occlusion by leveraging global structural context. Third, the DySample operator is introduced to replace static interpolation, enabling content-aware feature flow reconstruction. Experimental results demonstrate that SLD-YOLO11 achieves an mAP@0.5 of 97.4% on a self-collected maize field dataset, significantly outperforming YOLOv8n, YOLOv10n, YOLOv11n, and mainstream lightweight variants. Notably, the model achieves Zero Inter-class Misclassification between maize and weeds, establishing high safety standards for weeding operations. To further bridge the gap between visual perception and precision operations, a Visual Weed-Crop Competition Index (VWCI) is innovatively proposed. By integrating detection bounding boxes with species-specific morphological correction coefficients, the VWCI quantifies field weed pressure with low cost and high throughput. Regression analysis reveals a high consistency (R² = 0.70) between the automated VWCI and manual ground-truth coverage. This study not only provides a robust detector but also offers a reliable decision-making basis for real-time variable-rate spraying by intelligent weeding robots. Full article

Non-invasive electrocardiogram (ECG) and respiratory signals are easy to acquire via low-cost sensors, making them promising alternatives for sleep staging. However, existing methods using these signals often yield insufficient accuracy. To address this challenge, we incrementally optimized the sleep staging model by designing a structured experimental workflow: we first preprocessed respiratory and ECG signals, then extracted fused features using an enhanced feature selection technique, which not only reduces redundant features, but also significantly improves the class discriminability of features. The resulting fused features serve as a reliable feature subset for the classifier. In the meantime, we proposed a hybrid optimization algorithm that integrates the snake optimization algorithm (SO) and ant colony optimization algorithm (ACO) for automated hyperparameter optimization of support vector machines (SVMs). Experiments were conducted using two PSG-derived public datasets, the Sleep Heart Health Study (SHHS) and MIT-BIH Polysomnography Database (MIT-BPD), to evaluate the classification performance of multimodal features compared with single-modal features. Results demonstrate that the bimodal staging using SHHS multimodal signals significantly outperformed single-modal ECG-based methods, and the overall accuracy of the SHHS dataset was improved by 12%. The SVM model optimized using the hybrid Snake–ACO algorithm achieved an average accuracy of 89.6% for wake versus sleep classification on the SHHS dataset, representing a 5.1% improvement over traditional grid search methods. Under the subject-independent partitioning experiment, the wake versus sleep classification task maintained good stability with only a 1.8% reduction in accuracy. This study provides novel insights for non-invasive sleep monitoring and clinical decision support. Full article

Microbiological analysis is crucial for identifying species, assessing infections, and diagnosing infectious diseases, thereby supporting both research studies and medical diagnosis. In response to these needs, accurate and efficient identification of bacterial colonies is essential. Conventionally, this process is performed through manual counting and visual inspection of colonies on agar plates. However, this approach is prone to several limitations arising from human error and external factors such as lighting conditions, surface reflections, and image resolution. To overcome these limitations, an automated bacterial colony counting and classification system was developed by integrating a custom-designed imaging device with advanced deep learning models. The imaging device incorporates controlled illumination, matte-coated surfaces, and a high-resolution camera to minimize reflections and external noise, thereby ensuring consistent and reliable image acquisition. Image-processing algorithms implemented in MATLAB were employed to detect bacterial colonies, remove background artifacts, and generate cropped colony images for subsequent classification. A dataset comprising nine bacterial species was compiled and systematically evaluated using five deep learning architectures: ResNet-18, ResNet-50, Inception V3, GoogLeNet, and the state-of-the-art EfficientNet-B0. Experimental results demonstrated high colony-counting accuracy, with a mean accuracy of 90.79% ± 5.25% compared to manual counting. The coefficient of determination (R² = 0.9083) indicated a strong correlation between automated and manual counting results. For colony classification, EfficientNet-B0 achieved the best performance, with an accuracy of 99.78% and a macro-F1 score of 0.99, demonstrating strong capability in distinguishing morphologically distinct colonies such as Serratia marcescens. Compared with previous studies, this research provides a time-efficient and scalable solution that balances high accuracy with computational efficiency. Overall, the findings highlight the potential of combining optimized imaging systems with modern lightweight deep learning models to advance microbiological diagnostics and improve routine laboratory workflows. Full article