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15 pages, 436 KiB  
Article
An Exploratory Investigation of Heart Rate Variability in Response to Exercise Training and Detraining in Young and Middle-Aged Men
by Andres E. Carrillo, Petros C. Dinas, Paraskevi Gkiata, Alexa R. Ferri, Glen P. Kenny, Yiannis Koutedakis, Athanasios Z. Jamurtas, George S. Metsios and Andreas D. Flouris
Biology 2025, 14(7), 794; https://doi.org/10.3390/biology14070794 - 30 Jun 2025
Viewed by 401
Abstract
We examined heart rate (HR) and heart rate variability (HRV) in young and middle-aged men after a period of detraining that immediately followed the completion of an exercise training program. Eight young (27.8 ± 3.8 years) and ten middle-aged (41.9 ± 3.8 years) [...] Read more.
We examined heart rate (HR) and heart rate variability (HRV) in young and middle-aged men after a period of detraining that immediately followed the completion of an exercise training program. Eight young (27.8 ± 3.8 years) and ten middle-aged (41.9 ± 3.8 years) men were randomly assigned to complete an 8-week exercise training program that included either aerobic (young: n = 3; middle-aged: n = 2), resistance (young: n = 3; middle-aged: n = 3), or combined (aerobic/resistance) (young: n = 2; middle-aged: n = 5) exercise. Thereafter, participants ceased all planned exercise training activities during an 8-week detraining period. Resting HR and HRV were assessed at baseline, after exercise training, and after detraining. An analysis of mean differences between age groups at each time-point revealed a significantly higher standard deviation of normal RR intervals (SDNN), square root of the mean of squared differences between successive RR intervals (RMSSD), high-frequency (HF) band (0.15–0.40 Hz), and cardiac vagal index (CVI) in young participants when compared to middle-aged participants at baseline (p ≤ 0.019) and after detraining (p ≤ 0.045), but not after the 8-week exercise training intervention (p ≥ 0.057). Additionally, in middle-aged participants, we observed a significant negative association between the percent change in HRV indices (RMSSD, HF, and CVI) and systolic blood pressure in response to detraining (p < 0.05). In conclusion, young participants had higher levels of HRV indices at baseline, reflecting greater cardiac vagal modulation when compared to middle-aged participants. We showed that these age-related differences in HRV are diminished following exercise training but are reestablished following 8 weeks of detraining. Given that age-related attenuations in HRV may reflect changes in cardiovascular health, it is important to further investigate the relationships between HRV, exercise training and detraining, aging, and the risk of poor health outcomes. Full article
(This article belongs to the Section Physiology)
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15 pages, 1039 KiB  
Article
Effects of a Combined Plyometric and Resistance Training Programme on Adolescent Rugby Union Players
by Cian M. Walsh, Joseph I. Esformes, Jeremy A. Moody and Paul J. Byrne
Muscles 2025, 4(2), 17; https://doi.org/10.3390/muscles4020017 - 2 Jun 2025
Viewed by 859
Abstract
Background: Previous work has found that combining plyometric and resistance training in a single session can be effective in improving maximum strength (muscle contraction ability), vertical jumping, and sprint acceleration performance in young soccer players. However, the literature is scarce in relation to [...] Read more.
Background: Previous work has found that combining plyometric and resistance training in a single session can be effective in improving maximum strength (muscle contraction ability), vertical jumping, and sprint acceleration performance in young soccer players. However, the literature is scarce in relation to young rugby union players. Thus, the purposes of the present study were to examine the effects of a 6-week combined training (CT) programme that combined plyometric and resistance training in the same session on physical performance measures in adolescent male rugby union players and whether a 4-week period of plyometric training exclusion (Detraining) affects training adaptations. Methods: The participants (n = 15) completed a 6-week CT intervention and 4 weeks of plyometric detraining during the schoolboy rugby union in-season. A performance testing battery was conducted pre-intervention, post-intervention, and 4 weeks post-intervention. Results: A repeated measures ANOVA showed a significant effect for time on CMJ variables (mean power, mean force, and modified reactive strength index [RSI]), 3RM back squat strength, and 505 test time (p < 0.05). Pairwise comparisons revealed that CMJ variables (mean force, mean power, and peak power), 3RM back squat strength, and 505 test performance significantly increased from pre-intervention to post-intervention (p < 0.05). The 4-week plyometric detraining period significantly augmented CMJ variables (mean force, mean power, and modified RSI) and performance measures (standing broad jump [SBJ], 20 m sprint time, 505 test, and 3RM strength). Conclusions: The findings indicate that a 6-week CT programme can augment measures of lower-body power, maximal strength, and change of direction performance in adolescent male rugby union players, and a 4-week resistance training-only period (plyometric detraining) does not negatively affect performance adaptations. Full article
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12 pages, 1081 KiB  
Article
Quantifying the Effects of Detraining on Female Basketball Players Using Physical Fitness Assessment Sensors
by Enrique Flórez-Gil, Alejandro Vaquera, Daniele Conte and Alejandro Rodríguez-Fernández
Sensors 2025, 25(7), 1967; https://doi.org/10.3390/s25071967 - 21 Mar 2025
Viewed by 523
Abstract
This study leverages physical fitness assessment sensors to investigate the effects of a brief in-season break (detraining period) on the physical performance of female basketball players. Sixty-seven players (Senior (n = 19), U18 (n = 19), and U14 (n = 29)) were evaluated [...] Read more.
This study leverages physical fitness assessment sensors to investigate the effects of a brief in-season break (detraining period) on the physical performance of female basketball players. Sixty-seven players (Senior (n = 19), U18 (n = 19), and U14 (n = 29)) were evaluated before and after a 3-week break using sensor-derived data from a countermovement jump (CMJ), an Abalakov jump (ABK), a linear speed test (20 m sprint), a seated medicine ball throw test (SMBT), and a Basketball-Specific Agility Test (TEA-Basket). The Total Score of Athleticism (TSA), computed as the mean Z-Score across tests, served as a composite indicator of physical fitness. Data obtained from performance sensors revealed significant interactions between time and category for the CMJ, ABK, 20 m sprint, and SMBT, while TEA-Basket measurements showed no significant changes. Time and baseline fitness level interactions were also significant for the CMJ, ABK, and SMBT but not for sprint time or the TEA-Basket. Despite observed declines in explosive strength, speed, and upper-body power across all groups, TSA scores remained stable. These findings underscore the utility of sensor-based evaluation methods in highlighting the adverse effects of short-term detraining and emphasize the necessity of tailored training strategies during competitive breaks. Full article
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15 pages, 477 KiB  
Article
Comparison of Five Rehabilitation Interventions for Acute Ischemic Stroke: A Randomized Trial
by József Tollár, Szilvia Kóra, Petra Kós, Zoltán Vadászi, István Drotár, Péter Prukner, György Wersényi, Tamás Haidegger, Tomas Vetrovsky and Tibor Hortobágyi
J. Clin. Med. 2025, 14(5), 1648; https://doi.org/10.3390/jcm14051648 - 28 Feb 2025
Viewed by 2074
Abstract
Background: Comparative efficacy of rehabilitation interventions in persons with acute ischemic stroke (PwS) is limited. This randomized trial assessed the immediate and lasting effects of five interventions on clinical and mobility outcomes in 75 PwS. Methods: Five days after stroke, 75 PwS were [...] Read more.
Background: Comparative efficacy of rehabilitation interventions in persons with acute ischemic stroke (PwS) is limited. This randomized trial assessed the immediate and lasting effects of five interventions on clinical and mobility outcomes in 75 PwS. Methods: Five days after stroke, 75 PwS were randomized into five groups: physical therapy (CON, standard care, once daily); walking with a soft robotic exoskeleton (ROB, once daily); agility exergaming once (EXE1, once daily) or twice daily (EXE2, twice daily); and combined EXE1+ROB in two daily sessions. Interventions were performed 5 days per week for 3 weeks. Outcomes were assessed at baseline, post-intervention, and after 5 weeks of detraining. Results: Modified Rankin Scale (primary outcome) and Barthel Index showed no changes. EXE1, EXE2, ROB, and EXE1+ROB outperformed standard care (CON) in five secondary outcomes (Berg balance scale, 10m walking speed, 6-min walk test with/without robot, standing balance), with effects sustained after 5 weeks. Dose effects (EXE1 vs. EXE2) were minimal, while EXE1+ROB showed additive effects in 6-min walk tests. Conclusions: These novel comparative data expand evidence-based options for therapists to design individualized rehabilitation plans for PwS. Further confirmation is needed. Full article
(This article belongs to the Special Issue Acute Ischemic Stroke: Current Status and Future Challenges)
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23 pages, 3870 KiB  
Article
Separate and Combined Effects of Moderate-Intensity Exercise Training and Detraining with Protocatechuic Acid (PCA) on Myokines and Insulin-Signaling Pathways in Male Wistar Rats: A Preclinical Randomized Study
by Hira Shakoor, Jaleel Kizhakkayil, Yauhen Statsenko and Carine Platat
Metabolites 2025, 15(2), 87; https://doi.org/10.3390/metabo15020087 - 1 Feb 2025
Cited by 1 | Viewed by 1262
Abstract
Background: Exercise training positively modulates myokine secretion and improves glucose metabolism. Herein, we analyzed the effect of moderate-intensity training, detraining, and Protocatechuic Acid (PCA) supplementation on myokine secretions and regulation of insulin-signaling pathways. Methods: A five-arm study was conducted on 47 healthy [...] Read more.
Background: Exercise training positively modulates myokine secretion and improves glucose metabolism. Herein, we analyzed the effect of moderate-intensity training, detraining, and Protocatechuic Acid (PCA) supplementation on myokine secretions and regulation of insulin-signaling pathways. Methods: A five-arm study was conducted on 47 healthy male Wistar rats, trained at a moderate intensity level for four weeks (T0-T4). Animals were randomly classified into groups according to PCA supplementation and exercise durations: four weeks of Aerobic Training with or without PCA (AT4, AT4-PCA), eight weeks of Aerobic Training with or without PCA (AT8, AT8-PCA), and PCA Vehicle Control (VC). The animals were followed up until week 12 (T12). We decapitated six rats at T0 and T4, four rats per group at T8, and three rats per group at T12. Myokines (IGF-1, IL-6, FGF-21, myostatin, and irisin) were analyzed with ELISA. Western blot analysis measured protein expression of insulin-signaling pathways and GLUT-4 in the gastrocnemius muscle. Results: The IL-6 levels increased significantly (p < 0.01) with 8-week training in AT8 by 34% and AT8-PCA by 32%, compared to groups trained for only 4 weeks (AT4 and AT4-PCA). Similarly, the PI3K, and GLUT-4 expression improved in AT8 and AT8-PCA at T8. Training for 4 weeks improved IGF-1 levels, but a further 14% improvement was observed with 8-week training in AT8 at T8. Myostatin level significantly dropped by 27% even with 4-week training (p < 0.001). However, detraining increased the myostatin levels in all groups, but in AT8-PCA with PCA dose, myostatin reduced by 11% compared to AT8 at T12. PCA supplementation reduced the FGF-21 levels by 54% during detraining at T12 in AT8-PCA compared to AT8. However, the irisin level did not change markedly in any group. Conclusions: Physical training (with and without PCA) modulates myokine production and improves glucose metabolism, but the benefits are lost after detraining. Full article
(This article belongs to the Special Issue Diet and Nutrition in Relation to Metabolic Health)
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21 pages, 3119 KiB  
Article
Effect of Different Reduced Training Frequencies After 12 Weeks of Concurrent Ballistic and Aerobic Training on Muscle Power and Triceps Brachii Muscle Architecture
by Thomas Mpampoulis, Spyridon Methenitis, Angeliki N. Stasinaki, Nikolaos Zaras, Gregory C. Bogdanis and Gerasimos Terzis
J. Funct. Morphol. Kinesiol. 2025, 10(1), 37; https://doi.org/10.3390/jfmk10010037 - 19 Jan 2025
Viewed by 3392
Abstract
Background/Objectives: The aim of the present study was to investigate the effect of two long-term reduced concurrent training frequencies (incorporating power training for the upper and high-intensity interval aerobic training for the lower extremities), in which participants performed one training session every either [...] Read more.
Background/Objectives: The aim of the present study was to investigate the effect of two long-term reduced concurrent training frequencies (incorporating power training for the upper and high-intensity interval aerobic training for the lower extremities), in which participants performed one training session every either 7 or 14 days, after 12 weeks of systematic concurrent training on upper extremities’ muscle strength, power, and morphology in young females. Methods: After a 12-week concurrent resistance and aerobic training period, participants were assigned into three groups and performed either one training session every 7 days (G7), or once every 14 days (G14), or detraining (GD) for 12 weeks, followed by 12 additional weeks of detraining. Results: Performance and muscle mass increased after the initial 12-week training period. After the reduced training frequency period, bench press 1-RM and aerobic power remained unchanged in G7 and decreased significantly in G14 (−5.9 ± 4.9%; −1.4 ± 4.5%). Muscle power and muscle thickness of the triceps branchii long head decreased significantly in G7 (−9.8 ± 7.7%; −0.9 ± 0.6%; respectively, p < 0.05) and G14 (−10.9 ± 7.6%; −2.8 ± 2.7%, respectively, p < 0.05), without significant differences between groups (p > 0.05). Conclusions: In conclusion, 12 weeks of systematic concurrent resistance (upper extremities) and aerobic training (lower extremities) induced significant improvements in upper extremities muscle power/strength and muscle architecture characteristics. Both reduced training frequencies led to significant reductions in power performance. Thus, performing one training session every 2 weeks for 3 months may preserve 90 to 95% of the muscle power/strength, aerobic power and 72% of muscle mass adaptations achieved with systematic concurrent training. However, greater preservations in the above parameters could be observed if the training frequency is one training session per week. Full article
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12 pages, 691 KiB  
Case Report
Left Ventricular Hypertrabeculation (LVHT) in Athletes: A Negligible Finding?
by Rokas Jagminas, Rokas Šerpytis, Pranas Šerpytis and Sigita Glaveckaitė
Medicina 2025, 61(1), 32; https://doi.org/10.3390/medicina61010032 - 28 Dec 2024
Viewed by 1280
Abstract
Left ventricular hypertrabeculation (LVHT) used to be a rare phenotypic trait. With advances in diagnostic imaging techniques, LVHT is being recognised in an increasing number of people. The scientific data show the possibility of the overdiagnosis of this cardiomyopathy in a population of [...] Read more.
Left ventricular hypertrabeculation (LVHT) used to be a rare phenotypic trait. With advances in diagnostic imaging techniques, LVHT is being recognised in an increasing number of people. The scientific data show the possibility of the overdiagnosis of this cardiomyopathy in a population of people who have very high levels of physical activity. We describe the case of a young athlete with no medical history, who presented with syncope during a marathon running race. Initial evaluation showed elevated troponin I; transthoracic echocardiography showed a trabeculated ventricle and subsequent cardiac magnetic resonance (CMR) revealed left ventricular hypertrabeculation (LVHT). During subsequent evaluation by tilt table testing, vasovagal syncope was identified as the likely aetiology of the syncope. The patient was advised to cease sports and stimulants like caffeine use. At the 29-month follow-up, CMR showed the normalisation of the non-compacted to compacted myocardial ratio and an improvement in left ventricular function, with no further syncopal episodes reported. This is an example of the physiological hypertrabeculation of the LV apex in a recreational endurance athlete, with the normalisation of the non-compacted to compacted myocardial layer ratio after detraining. Physiological hypertrabeculation, a benign component of exercise-induced cardiac remodelling, must be differentiated from non-compaction cardiomyopathy and other pathologies causing syncope. This case underscores the importance of distinguishing physiological hypertrabeculation from pathological LVHT in athletes, highlighting that exercise-induced cardiac remodelling can normalise with detraining. Full article
(This article belongs to the Section Cardiology)
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13 pages, 761 KiB  
Article
Impact of a Three-Month Training Break on Swimming Performance in Athletes with Intellectual Disability
by Glykeria Kyriakidou, George Tsalis and Christina Evaggelinou
Sports 2024, 12(12), 330; https://doi.org/10.3390/sports12120330 - 2 Dec 2024
Viewed by 1130
Abstract
This study aimed to ascertain whether there were any differences in anthropometrics, heart rate, and swimming performance parameters in athletes with intellectual disabilities (ID) before and after a three-month training break. A total of 21 athletes participated in the study, comprising 16 males [...] Read more.
This study aimed to ascertain whether there were any differences in anthropometrics, heart rate, and swimming performance parameters in athletes with intellectual disabilities (ID) before and after a three-month training break. A total of 21 athletes participated in the study, comprising 16 males and 5 females, with a mean age of 28.3 ± 8.7 years. All participants had ID, and six of them had Down syndrome. The study participants were classified as S14 athletes from a local swimming club. All participants had a minimum of four years of swimming experience and attended two to three one-hour sessions per week for eight consecutive months. All athletes completed two trials of 25 m freestyle swimming, one at the end of a training session and the other at the beginning of a new session. The measurements included weight, body mass index (BMI), handgrip strength (HGS), heart rate (pre- and post-trial), performance (T25), stroke count (SC), stroke length (SL), stroke rate, and the SWOLF efficiency index. The results demonstrated statistically significant elevations in weight (80.2 ± 16.1 to 81.7 ± 15.9), BMI (26.8 ± 5.5 to 27.2 ± 5.5), T25 (33.1 ± 17.1 to 35.6 ± 18), SC (19.3 ± 6.1 to 20.7 ± 7.2), and SWOLF (52.4 ± 22.0 to 56.3 ± 25.2) and a reduction in SL (1.39 ± 0.48 to 1.27 ± 0.42). However, no significant differences were observed in the remaining parameters. Significant correlations were found for body weight, BMI, HGS, and SWOLF with T25 throughout the study. It was concluded that individuals with ID experienced a decline in 25 m swimming performance due to technical rather than physiological factors after three months of detraining. Full article
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11 pages, 805 KiB  
Article
Effects of Different Detraining Periods on the Physical Fitness of Older Adults with Cardiometabolic Risk Factors
by Mabel Diesel, Vanessa de Mattos Martini, Ian Takimoto Schmiegelow, Carlos Augusto de Sousa, Cíntia de la Rocha Freitas, Aline Mendes Gerage and Rodrigo Sudatti Delevatti
Int. J. Environ. Res. Public Health 2024, 21(12), 1550; https://doi.org/10.3390/ijerph21121550 - 23 Nov 2024
Viewed by 885
Abstract
Objective: To verify the effects of two different detraining periods on the physical fitness of older adults with cardiometabolic risk factors. Methods: This observational study encompassed older individuals with cardiometabolic risk factors, who were assessed after two different detraining periods: 1 month (1DT) [...] Read more.
Objective: To verify the effects of two different detraining periods on the physical fitness of older adults with cardiometabolic risk factors. Methods: This observational study encompassed older individuals with cardiometabolic risk factors, who were assessed after two different detraining periods: 1 month (1DT) and 3 months (3DT). Physical fitness was assessed using the 30-s sit to stand test (STS), 30-s arm curl, chair sit-and-reach, back scratch, timed up and go, and 6-min walk test (6MWT). The comparison between the different periods was carried out using absolute differences (Δ = posttest-pretest) and relative differences (Δ% = (Δ/pretest) × 100), with α = 0.05. Results: Eight older adults were assessed (70.3 ± 7.48 years, 4 female/4 male). Improvements in the STS (+1.88 repetitions; p = 0.007) and 6MWT (+17.38 m; p = 0.007) were found after 1DT. After 3DT, a worsening was observed in the 6MWT (−26.38 m; p = 0.018). The arm curl test worsened in both detraining periods (1DT: −1.38 repetitions; 3DT: −3.5 repetitions; p = 0.001). When comparing Δ% of 1DT and 3DT, STS and 6MWT showed differences, with p = 0.024 and p = 0.005, respectively. Conclusions: The 1-month detraining period had a positive effect on some physical fitness components, while 3 months induced a decline in cardiorespiratory fitness. Upper limb strength appears to be the component most susceptible to detraining. Full article
(This article belongs to the Special Issue 2nd Edition: Physical Fitness in an Aged Population)
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12 pages, 1024 KiB  
Article
Effects of a 4–Week Detraining Period After 12 Weeks of Combined Training Using Different Weekly Frequencies on Health–Related Physical Fitness in Older Adults
by Lucas Betti Domingues, Vinícius Mallmann Schneider, Rodrigo Flores de Abreu, Leandro de Oliveira Carpes and Rodrigo Ferrari
Int. J. Environ. Res. Public Health 2024, 21(11), 1433; https://doi.org/10.3390/ijerph21111433 - 29 Oct 2024
Cited by 1 | Viewed by 2078
Abstract
Background: Detraining refers to the decline in physical fitness that occurs after the cessation of exercise, compromising the adaptations resulting from regular exercise training. To understand how long the benefits acquired from an exercise program can be maintained, the present study evaluated the [...] Read more.
Background: Detraining refers to the decline in physical fitness that occurs after the cessation of exercise, compromising the adaptations resulting from regular exercise training. To understand how long the benefits acquired from an exercise program can be maintained, the present study evaluated the detraining effects of a 4–week exercise cessation period in older adults who performed combined training at various weekly frequencies for 12 weeks. Methods: This randomized controlled trial assigned participants to one of two training programs: a combined training program twice a week (CT2) or four times a week (CT4) over a period of 12 weeks, followed by a four–week detraining period. The resistance training consisted of six bodyweight exercises, while the aerobic training involved either walking or running. Both the CT2 and CT4 groups completed the same total training volume and overload each week; the only difference was the number of training sessions per week. Assessments were conducted at baseline, after the training period, and after the detraining period, and included the 30–s and five–repetition chair–stand tests, isometric handgrip strength, body mass index (BMI), waist circumference, and waist–to–height ratio. Results: Thirty–one participants completed the study (CT2: 17 and CT4: 14). The groups presented similar attendance records during the training period (CT2: 96 ± 18% versus CT4: 94 ± 19%). After the 12–week training period, CT2 and CT4 improved lower limb strength, CT2 improved upper limb strength, and CT4 reduced waist circumference and waist–to–height ratio compared to baseline. After the 4–week detraining period, the lower limb strength remained improved in both groups (CT2: 4 ± 1 repetition; p < 0.001 and CT4: 4 ± 1 repetition; p < 0.001) when compared to the corresponding baseline values. The handgrip strength decreased in CT2 compared to post–training values. And the body composition benefit in CT4 was not sustained after detraining. Conclusions: The effects of 4 weeks of detraining after 12 weeks of training performed two or four times per week are similar on some but not all health-related physical fitness parameters. Full article
(This article belongs to the Special Issue 2nd Edition: Physical Fitness in an Aged Population)
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17 pages, 1832 KiB  
Article
Long-Term Physical Activity Mitigates Inflammaging Progression in Older Adults Amidst the COVID-19 Pandemic
by Carlos André Freitas dos Santos, Ariane Nardy, Renato Jimenez Gomes, Brenda Rodrigues Silva, Fernanda Rodrigues Monteiro, Marcelo Rossi, Jônatas Bussador do Amaral, Vitória Paixão, Mauro Walter Vaisberg, Gislene Rocha Amirato, Rodolfo P. Vieira, Juliana de Melo Batista dos Santos, Guilherme Eustaquio Furtado, Ana Paula Ribeiro, Patrícia Colombo-Souza, Alessandro Ferrari Jacinto and Andre Luis Lacerda Bachi
Int. J. Environ. Res. Public Health 2024, 21(11), 1425; https://doi.org/10.3390/ijerph21111425 - 27 Oct 2024
Viewed by 2581
Abstract
Background: Inflammaging and physical performance were investigated in older adults before and after the COVID-19 pandemic. Methods: Older women (n = 18) and men (n = 7) (mean age = 73.8 ± 7.1) were evaluated before the COVID-19 pandemic (PRE), 12 [...] Read more.
Background: Inflammaging and physical performance were investigated in older adults before and after the COVID-19 pandemic. Methods: Older women (n = 18) and men (n = 7) (mean age = 73.8 ± 7.1) were evaluated before the COVID-19 pandemic (PRE), 12 months after the lockdown (POST), and 10 months after resuming exercise training (POST-TR). Physical tests [gait speed (GS) and timed-up-and-go (TUG)]; muscle strength (handgrip—HG); and serum cytokine levels were assessed. Results: Older women showed higher GS and TUG at POST than PRE and POST-TR but lower HG at POST-TR than PRE, whereas older men exhibited lower HG at POST and POST-TR than PRE. Both groups presented (1) lower IL-10 and IL-12p70 values in contrast to higher IL-6/IL-10 and IL-8/IL-10 ratios at POST than PRE; (2) higher IL-10 values and lower IL-8/IL-10 ratio at POST-TR than POST; (3) higher IL-12p70/IL-10 ratio at POST-TR than PRE and POST. Particularly, older women showed (4) lower IL-6 values at POST and POST-TR than PRE; (5) lower IL-8 and IL-10 values at POST-TR than POST; (6) and higher TNF-α/IL-10 and IFN-γ/IL-10 ratios at POST than PRE and POST-TR. Significant correlations between the variables were found in both groups. Discussion: During the COVID-19 pandemic, detraining and resumption of exercise training promoted distinct alterations in physical capacity and inflammaging among older women and older men. Full article
(This article belongs to the Special Issue How Physical Activity Affects the Immune System)
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17 pages, 2813 KiB  
Article
Cardiometabolic and Cellular Adaptations to Multiple vs. Single Daily HIIT Sessions in Wistar Rats: Impact of Short-Term Detraining
by Liliane Vanessa Costa-Pereira, Bruno Ferreira Mendes, Caíque Olegário Diniz Magalhães, Cíntia Maria Rodrigues, Júllia Alves de Andrade, Ramona Ramalho Souza de Pereira, Elizabethe Adriana Esteves, Ricardo Cardoso Cassilhas, Eric Francelino Andrade, Fernando Gripp, Flávio Castro de Magalhães, Kinulpe Honorato Sampaio, Alex Cleber Improta-Caria, Fabiano Trigueiro Amorim and Marco Fabrício Dias-Peixoto
Metabolites 2024, 14(8), 447; https://doi.org/10.3390/metabo14080447 - 14 Aug 2024
Viewed by 1651
Abstract
Multiple short daily bouts of HIIT are more effective than single daily sessions in improving cardiometabolic and cellular adaptations in rats. We hypothesize that a short period of detraining is sufficient to abolish the superior adaptive responses to multiple versus single daily sessions [...] Read more.
Multiple short daily bouts of HIIT are more effective than single daily sessions in improving cardiometabolic and cellular adaptations in rats. We hypothesize that a short period of detraining is sufficient to abolish the superior adaptive responses to multiple versus single daily sessions of HIIT in rats. Male rats were divided into untrained, 1xHIIT, and 3xHIIT groups. Over eight weeks, the 1xHIIT group performed 115 min single daily sessions of HIIT, while the 3xHIIT group performed three 5 min sessions with 4 h intervals. After training, both groups remained sedentary for four weeks (detraining). Resting oxygen consumption (VO2), body composition, glucose/insulin tolerance, and blood pressure were recorded. After euthanasia, cardiac function/histology and gastrocnemius mitochondrial density were analyzed. After training, both 1xHIIT and 3xHIIT protocols induced similar improvements in VO2, maximal oxygen uptake (VO2max), cardiac function/hypertrophy, and gastrocnemius mitochondrial density. These effects were maintained even after detraining. Only the 3xHIIT protocol improved insulin sensitivity. After detraining, this effect was abolished. After training, both 1xHIIT and 3xHIIT protocols reduced adiposity. After detraining, the adiposity increased in both groups, with a more pronounced increase in the 3xHIIT rats. A four-week detraining period abolishes the superior adaptive responses to multiple versus single daily HIIT sessions in rats. Full article
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17 pages, 1692 KiB  
Article
Effect of Different Reduced Training Frequencies after 12 Weeks of Concurrent Resistance and Aerobic Training on Muscle Strength and Morphology
by Thomas Mpampoulis, Angeliki N. Stasinaki, Spyridon Methenitis, Nikolaos Zaras, Gregory C. Bogdanis and Gerasimos Terzis
Sports 2024, 12(7), 198; https://doi.org/10.3390/sports12070198 - 22 Jul 2024
Cited by 3 | Viewed by 12140
Abstract
The aim of the study was to investigate the effect of two long-term reduced concurrent training modalities, in which participants performed one training session every either 7 or 14 days, after 12 weeks of systematic concurrent resistance and aerobic training, on lower extremities’ [...] Read more.
The aim of the study was to investigate the effect of two long-term reduced concurrent training modalities, in which participants performed one training session every either 7 or 14 days, after 12 weeks of systematic concurrent resistance and aerobic training, on lower extremities’ muscle strength, power, and morphology in young females. After the 12-week training period, participants were assigned into three groups and performed either one training session every 7 days (G7) or once every 14 days (G14), or detraining (GD), for 12 weeks, followed by 12 additional weeks of detraining. The following were measured before, after the systematic training period, after the end of the reduced training frequency period, and after the end of complete detraining: body composition, leg press 1-RM, countermovement jump, quadriceps cross-sectional area (CSA), vastus lateralis muscle architecture, and maximum aerobic power. Performance and muscle mass increased after the initial 12-week training period. Thereafter, leg press 1-RM, quadriceps CSA, and aerobic power remained unchanged in the G7 group, but decreased in G14 (−4.4 ± 3.5%; −5.9 ± 1.8%; −9.0 ± 7.8%, respectively, p < 0.05), maintaining 95.6 ± 3.5%, 94.1 ± 1.8%, and 91.0 ± 7.8% of the initial training adaptations, respectively. In conclusion, performing one training session every 2 weeks for 3 months may preserve 90 to 95% of the muscle mass/strength and aerobic power adaptations achieved with systematic concurrent training. Full article
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17 pages, 2744 KiB  
Article
Effect of Detraining on Muscle Strength, Functional Capacity, Mental Health, and Body Composition in Individuals with Spinal Cord Injury
by Lucas Almada, Lucas Santos, Karla Freitas, Joel Rodrigues, Elizângela Diniz, Mauro Mazini-Filho, Luís Leitão, Eveline Pereira, Cláudia Oliveira and Osvaldo Moreira
Int. J. Environ. Res. Public Health 2024, 21(7), 900; https://doi.org/10.3390/ijerph21070900 - 10 Jul 2024
Cited by 1 | Viewed by 2160
Abstract
Spinal cord injury (SCI) is a condition that significantly affects the quality of life (QoL) of individuals, causing motor, physiological, social, and psychological impairments. Physical exercise plays a crucial role in maintaining the health and functional capacity of these individuals, helping to minimize [...] Read more.
Spinal cord injury (SCI) is a condition that significantly affects the quality of life (QoL) of individuals, causing motor, physiological, social, and psychological impairments. Physical exercise plays a crucial role in maintaining the health and functional capacity of these individuals, helping to minimize the negative impacts of SCI. The aim of this study was to evaluate the effect of detraining (DT) (reduction or cessation of physical exercise) during the pandemic on five individuals with thoracic SCI. We assessed muscle strength using strength tests, functional capacity using a functional agility test, mental health using anxiety and depression inventories, and body composition using dual-energy X-ray absorptiometry (DEXA). The results after 33 months of DT showed significant losses in functional agility and MS, as well as a worsening in symptoms of anxiety and depression. It was observed that total body mass and fat mass (FM) exhibited varied behaviors among the individuals. Similarly, the results for lean body mass were heterogeneous, with one participant showing significant deterioration. It is concluded that DT caused by the pandemic worsened the physical and mental condition of individuals with SCI, highlighting the importance of continuous exercise for this population and underscoring the need for individual assessments to fully understand the impacts of DT. Full article
(This article belongs to the Special Issue The Effect of the Physical Activity on the Health of People)
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11 pages, 2548 KiB  
Article
Detraining’s Effects on Cardiorespiratory Fitness and Maximal and Explosive Strength in Army Soldiers: Does Age Matter?
by Alexis Arce-Álvarez, Ángelo Zaio, Camila Salazar-Ardiles, Cristian Álvarez, Pablo Merino-Muñoz, Manuel Vasquez-Muñoz, Mikel Izquierdo, Mauricio Castro and David C. Andrade
Sports 2024, 12(7), 183; https://doi.org/10.3390/sports12070183 - 1 Jul 2024
Viewed by 3160
Abstract
Purpose: This study investigated the impact of four weeks of age-dependent detraining on army soldiers’ cardiorespiratory fitness and maximal and explosive strength. Methods: Fourteen volunteer tactical athletes participated, divided into two age groups (20 to 29 and 30 to 40 years). Before and [...] Read more.
Purpose: This study investigated the impact of four weeks of age-dependent detraining on army soldiers’ cardiorespiratory fitness and maximal and explosive strength. Methods: Fourteen volunteer tactical athletes participated, divided into two age groups (20 to 29 and 30 to 40 years). Before and after the detraining period, we assessed their anthropometric measurements (weight, height, body mass index, fat mass, and fat-free mass), cardiorespiratory fitness (maximal oxygen uptake [VO2max] and ventilatory thresholds [VT1 and VT2]), and kinematic properties during a single-leg counter-moving jump (CMJ) test for both the dominant and non-dominant legs. Two-way ANOVA followed by the Holm–Sidak post hoc test was used. Results: The anthropometric and cardiovascular variables did not show significant differences between the groups. However, both groups exhibited a significantly reduced maximum time and speed at the VO2max. Furthermore, the flight time and maximum height during the CMJ significantly decreased in the non-dominant leg for both age groups. Notably, the dominant leg’s concentric impulse (CI) significantly reduced during the CMJ, but this effect was observed only in the 30–40 age group. There were significant differences between the two age groups. Conclusions: Our findings suggest that four weeks of detraining negatively impacts aerobic fitness and muscular strength, independently of age. However, the dominant leg may be more susceptible to detraining effects in army soldiers aged 30–40. Furthermore, as a perspective, our results strongly suggest that a detraining period could affect successful missions (aerobic performance deterioration), as well as promote a muscle imbalance between the legs, which could encourage muscle injuries and endanger combat missions. Full article
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