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22 pages, 1392 KB  
Article
Disaster Relief Coverage Path Planning for Fixed-Wing UAV Based on Multi-Selector Genetic Algorithm and Reinforcement Learning
by Jing Yang, Xuemeng Lu and Mingyang Cui
Aerospace 2026, 13(2), 192; https://doi.org/10.3390/aerospace13020192 - 17 Feb 2026
Viewed by 415
Abstract
When a fixed-wing Unmanned Aerial Vehicle (UAV) conducts All-Weather Post-Disaster Coverage Path Planning (PDCPP), the commonly used Sequential Path Coverage (SPC) method tends to generate redundant flight distance during turning transitions between adjacent coverage paths, which in turn increases the UAV’s flight energy [...] Read more.
When a fixed-wing Unmanned Aerial Vehicle (UAV) conducts All-Weather Post-Disaster Coverage Path Planning (PDCPP), the commonly used Sequential Path Coverage (SPC) method tends to generate redundant flight distance during turning transitions between adjacent coverage paths, which in turn increases the UAV’s flight energy consumption and thereby compromises the timeliness of rescue information acquisition. To address these challenges, this paper proposes a Multi-Selector Genetic Algorithm with Reinforcement Learning (MSGA-RL). It enhances population diversity through a distance-priority heuristic greedy initialization strategy, employs a multi-selector crossover operator to improve both solution diversity and convergence speed, and integrates a reinforcement learning-based individual retention mechanism with an elite pool protection strategy to prevent premature convergence. To simulate post-disaster scenarios, the disaster-affected area is modeled as a convex polygonal region with obstacles, while the flight energy consumption and stability of MSGA-RL are evaluated under different numbers of coverage paths. Simulation results indicate that, across all coverage path settings, MSGA-RL consistently achieves lower flight energy consumption than SPC, the Genetic Algorithm (GA), and the Dubins-based Enhanced Genetic Algorithm (DEGA), while exhibiting superior stability. In particular, in the convex quadrilateral scenario with 50 coverage paths, the flight energy consumption of MSGA-RL is reduced by 52.80%, 32.06%, and 15.96% compared with SPC, GA, and DEGA, respectively. Full article
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17 pages, 763 KB  
Article
Ultrasound Thawing Optimization as a Novel Strategy to Improve Quality of Slowly Frozen Chicken Breast
by Suelen Priscila Santos, Silvino Sasso Robalo, Monica Voss, Bianca Campos Casarin, Bibiana Alves dos Santos, Renius de Oliveira Mello, Juliano Smanioto Barin, Cristiano Ragagnin de Menezes, Paulo Cezar Bastianello Campagnol and Alexandre José Cichoski
Foods 2025, 14(19), 3446; https://doi.org/10.3390/foods14193446 - 8 Oct 2025
Cited by 1 | Viewed by 1316
Abstract
Chicken meat is highly consumed worldwide due to its nutritional value, but its high water content and abundance of polyunsaturated fatty acids make it particularly vulnerable to structural and oxidative damage during freezing and thawing. Slow freezing, in particular, generates large ice crystals [...] Read more.
Chicken meat is highly consumed worldwide due to its nutritional value, but its high water content and abundance of polyunsaturated fatty acids make it particularly vulnerable to structural and oxidative damage during freezing and thawing. Slow freezing, in particular, generates large ice crystals that severely impair water-holding capacity (WHC), increase drip loss, promote color deterioration, and intensify protein and lipid oxidation. Innovative thawing strategies are therefore required to mitigate these quality losses. Ultrasound (US) has been successfully applied to accelerate thawing of fast-frozen meat; however, its potential for slowly frozen chicken breast remains poorly understood. This study aimed to evaluate the effects of US-assisted thawing at two frequencies (25 and 130 kHz), two amplitudes (100% and 60%), and three operating modes (normal, sweep, and degas) on the quality of slowly frozen chicken breast. Conventional thawing required 50 min, yielding WHC of 9.87%, drip loss of 4.65%, free sulfhydryls of 16.38 µmol/g, and ∆E of 3.91. In contrast, the optimized US condition (25 kHz, 100% amplitude, sweep mode) thawed samples in only 18 min, with markedly improved WHC (23.14%), reduced drip loss (3.25%), higher preservation of free sulfhydryls (24.69 µmol/g), and minimal color change (∆E = 3.72). Conversely, less effective parameters (e.g., 130 kHz, 60% amplitude, normal mode) prolonged thawing and compromised quality, with WHC dropping to 9.96% and drip loss increasing to 9.05%. Overall, US reduced thawing time under all conditions, but quality responses depended strongly on the applied parameters. The present findings demonstrate the novelty of optimizing US frequency, amplitude, and mode for thawing slowly frozen chicken breast, highlighting sweep mode at 25 kHz and 100% amplitude as the most effective strategy. Future research should explore its scalability and industrial applicability for poultry processing. Full article
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13 pages, 951 KB  
Article
Evaluation of Acetabular Defects in Children with Cerebral Palsy: A Comparative Analysis of CT Measurements and Radiographic Parameters
by Domenic Grisch, Olivier Weber, Britta K. Krautwurst, Franziska L. Hatt, Michael Zellner, Christian von Deimling, Tobias Götschi, Bastian Sigrist and Thomas Dreher
Children 2025, 12(9), 1254; https://doi.org/10.3390/children12091254 - 17 Sep 2025
Viewed by 918
Abstract
Objectives: This retrospective study examines acetabular morphology and defects in children with cerebral palsy (CP). The study discovers the usefulness and reliability of a reconstructed 3D CT measurement technique and compares it to conventional radiographic measurements. Methods: 33 subjects with CP [...] Read more.
Objectives: This retrospective study examines acetabular morphology and defects in children with cerebral palsy (CP). The study discovers the usefulness and reliability of a reconstructed 3D CT measurement technique and compares it to conventional radiographic measurements. Methods: 33 subjects with CP who underwent hip reconstruction, including Dega osteotomy and varus derotation femoral osteotomy, were included and compared to an age-matched group of 42 typically developing children. We reproduced a three directional acetabular index (3DAI), including anterosuperior, superolateral and posterosuperior indices in CT analysis, and compared them with established radiographic measurements for the migration percentage (MP) and the acetabular index (AI). Results: The results showed significantly higher 3DAI in every direction of wall deficiency, accentuating the methods sensitivity for acetabular dysplasia. The interrater and test–retest reliability were robust with ICC = 0.939–0.988 for the CP group. Conventional radiographic measurements demonstrated better discriminative power for identifying hip dislocation and correlated strongly with the 3DAI (p < 0.001). Conclusions: The 3DAI method showcases an important addition to the conventional radiographic measurements by enabling a quantification of the defect amount and direction for operative planning. The study supports the potential of a 3D analysis in the improvement of diagnostic precision and suggests a continuous refinement of the CT measurement technique. Full article
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25 pages, 4782 KB  
Article
Improving Ti Thin Film Resistance Deviations in Physical Vapor Deposition Sputtering for Dynamic Random-Access Memory Using Dynamic Taguchi Method, Artificial Neural Network and Genetic Algorithm
by Chia-Ming Lin and Shang-Liang Chen
Mathematics 2024, 12(17), 2688; https://doi.org/10.3390/math12172688 - 29 Aug 2024
Cited by 1 | Viewed by 1589
Abstract
Many dynamic random-access memory (DRAM) manufacturing companies encounter significant resistance value deviations during the PVD sputtering process for manufacturing Ti thin films. These resistance values are influenced by the thickness of the thin films. Current mitigation strategies focus on adjusting film thickness to [...] Read more.
Many dynamic random-access memory (DRAM) manufacturing companies encounter significant resistance value deviations during the PVD sputtering process for manufacturing Ti thin films. These resistance values are influenced by the thickness of the thin films. Current mitigation strategies focus on adjusting film thickness to reduce resistance deviations, but this approach affects product structure profile and performance. Additionally, varying Ti thin film thicknesses across different product structures increase manufacturing complexity. This study aims to minimize resistance value deviations across multiple film thicknesses with minimal resource utilization. To achieve this goal, we propose the TSDTM-ANN-GA framework, which integrates the two-stage dynamic Taguchi method (TSDTM), artificial neural networks (ANN), and genetic algorithms (GA). The proposed framework requires significantly fewer experimental resources than traditional full factorial design and grid search method, making it suitable for resource-constrained and low-power computing environments. Our TSDTM-ANN-GA framework successfully identified an optimal production condition configuration for five different Ti thin film thicknesses: Degas temperature = 245 °C, Ar flow = 55 sccm, DC power = 5911 W, and DC power ramp rate = 4009 W/s. The results indicate that the deviation between the resistance values and their design values for the five Ti thin film thicknesses decreased by 86.8%, 94.1%, 95.9%, 98.2%, and 98.8%, respectively. The proposed method effectively reduced resistance deviations for the five Ti thin film thicknesses and simplified manufacturing management, allowing the required design values to be achieved under the same manufacturing conditions. This framework can efficiently operate on resource-limited and low-power computers, achieving the goal of real-time dynamic production parameter adjustments and enabling DRAM manufacturing companies to improve product quality promptly. Full article
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11 pages, 2165 KB  
Article
Rim Driven Thruster as Innovative Propulsion Element for Dual Phase Flows in Plug Flow Reactors
by Maximilian Lackner, Alexander Löhr, Felix Schill and Martin Van Essche
Fluids 2024, 9(7), 168; https://doi.org/10.3390/fluids9070168 - 22 Jul 2024
Cited by 4 | Viewed by 2639
Abstract
The purpose of this work was to test a new setup to pump water with entrained air for application in gas fermentation. A mixed flow, where gas is contained in a liquid to be pumped, rapidly reduces the efficiency of a conventional pump, [...] Read more.
The purpose of this work was to test a new setup to pump water with entrained air for application in gas fermentation. A mixed flow, where gas is contained in a liquid to be pumped, rapidly reduces the efficiency of a conventional pump, due to the compressibility of the gas. It is not always possible to degas the fluid, for instance in gas fermentation, which is preferably carried out in tubular reactors (loop fermenters) to achieve a high conversion rate of the gaseous feedstocks. Method: In this work, a rim-driven thruster (RDT) was tested in a lab-scale, cold flow model of a loop reactor with 5–30% (by volume) of gas fraction (air) in the liquid (water) as alternative propulsion element (6 m total pipe length, ambient temperature and pressure). As a result, it was found that the RDT, in connection with a guiding vane providing swirling motion to the two-phase fluid, could pump a mixed flow with up to 25.7% of gas content (by volume) at atmospheric pressure and 25 °C and 0.5 to 2 m/s flow speed. In conclusion, an RDT is advantageous over a classic propulsion element like a centrifugal pump or axial flow pump for transporting liquids with entrained gases. This article describes the potential of rim-driven thrusters, as known from marine propulsion, in biotechnology, the chemical industry, and beyond, to handle multiphase flows. Full article
(This article belongs to the Special Issue New Perspectives in Gas–Liquid Reactors)
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20 pages, 3475 KB  
Article
Alterations in Hydrological Responses under Changing Climate and Land Use/Land Cover across Contrasting Agroecological Environments: A Case Study on the Chemoga Watershed in the Upper Blue Nile Basin, Ethiopia
by Taye Minichil Meshesha, Atsushi Tsunekawa, Nigussie Haregeweyn, Mitsuru Tsubo, Ayele Almaw Fenta, Mulatu Liyew Berihun, Arega Mulu, Ashebir Sewale Belay, Dagnenet Sultan, Kindiye Ebabu, Tadesual Asamin Setargie, Samuel Berihun Kassa, Yoseph Buta Hailu and Takeshi Abe
Water 2024, 16(7), 1037; https://doi.org/10.3390/w16071037 - 4 Apr 2024
Cited by 11 | Viewed by 3494
Abstract
We analyzed hydrological responses to changing climate and land use/land cover (LULC) for the past (1985–2020) and future (2021–2080) in the Chemoga watershed of the Upper Blue Nile Basin. The watershed comprises four agroecological environments: Moist Kolla, Moist Weyna Dega, Moist Dega, and [...] Read more.
We analyzed hydrological responses to changing climate and land use/land cover (LULC) for the past (1985–2020) and future (2021–2080) in the Chemoga watershed of the Upper Blue Nile Basin. The watershed comprises four agroecological environments: Moist Kolla, Moist Weyna Dega, Moist Dega, and Wet Wurch. Past and projected LULC changes under business-as-usual (BAU) and land conservation (LC) scenarios were utilized. Climate projections from 2021 to 2080, under two Shared Socioeconomic Pathways (SSP2-4.5 and SSP5-8.5), were downscaled from Global Climate Models. Utilizing the Soil and Water Analysis Tool, we assessed impacts on mean annual surface runoff (SR) and evapotranspiration (ET). Maximum and minimum temperatures increased significantly in the past and future climate scenarios, with a significant rainfall increase observed under SSP5-8.5. Historical trends revealed a 16.6% increase in SR and 7% in ET from 1983–2002 to 2003–2020. Under BAU LULC with the SSP2-4.5 (SSP5-8.5) climate scenario, SR increased by 24% (26.1%) and ET by 3.1% (4.4%) from 2003–2020 to 2021–2050, followed by a subsequent SR rise of 13.7% (14.0%) and ET increase of 6.0% (5.7%) from 2021–2050 to 2051–2080. Conversely, the LC LULC with SSP2-4.5 (SSP5-8.5) resulted in a 5.3% (4.2%) SR decrease and ET increase of 9.7% (11.3%) from 2003–2020 to 2021–2050 and a further SR decrease of 1% (0.7%) and 6.1% (6.9%) ET increase from 2021–2050 to 2051–2080. The Moist Kolla agroecology experienced the highest SR increase due to vegetation clearances for commercial farming. Meanwhile, the LC scenario indicated substantial decreases in SR and marginal increases in ET in the Moist Weyna Dega agroecology due to forest restoration on steep slopes. Overall, SR showed greater sensitivity to LULC changes, while ET was more responsive to climate changes. The results emphasize considering diverse agroecological contexts for effective water resource management under changing climate and LULC scenarios. Full article
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10 pages, 2420 KB  
Article
The Separation Behavior of TiB2 during Cl2-Free Degassing Treatment of 5083 Aluminum Melt
by Cong Li, Mertol Gökelma, Wolfram Stets and Bernd Friedrich
Metals 2024, 14(4), 402; https://doi.org/10.3390/met14040402 - 29 Mar 2024
Cited by 1 | Viewed by 1784
Abstract
Utilizing titanium diboride (TiB2) inoculation for grain-refining purposes is a widely established practice in aluminum casthouses and foundries. Since this inoculation is usually implemented jointly with or between routine melt treatment steps ahead of casting, it is important to know whether [...] Read more.
Utilizing titanium diboride (TiB2) inoculation for grain-refining purposes is a widely established practice in aluminum casthouses and foundries. Since this inoculation is usually implemented jointly with or between routine melt treatment steps ahead of casting, it is important to know whether and how other melt treatment processes affect the fade of TiB2 particles. For the present study, we investigated the influence of degassing process on the separation behavior of TiB2 particles in aluminum melt. Multiple sampling methods were employed and the samples were analyzed via spectrometer analysis. The removal efficiency of TiB2 during the gas-purging process of 5083 aluminum melt was confirmed to be significant over 10 min of treatment time. The rate at which the TiB2 content decays was found to increase with the impeller rotary speed from 400 rounds per minute (rpm) to 700 rpm. The separation rate of TiB2 particles was obtained to be 0.05–0.08 min−1 by fitting the experimental data. Particle mapping results suggest that the TiB2 particles were separated to a dross layer. The obtained experimental results were used to quantitatively evaluate the conventional deterministic flotation model. The deviation between the conventional model and the experimental data was explained through the entrainment–entrapment (EE) model. Suggestions were made for future analytical and experimental works which may validate the EE model. Full article
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11 pages, 2576 KB  
Article
Influence of Choline Chloride/Urea and Glycerol Plasticizers on the Mechanical Properties of Thermoplastic Starch Plastics
by Jacob Staker, Sydney Schott, Riya Singh, Kourtney Collier, Gregory Druschel, Amanda P. Siegel and Andres Tovar
Polymers 2024, 16(6), 751; https://doi.org/10.3390/polym16060751 - 9 Mar 2024
Cited by 15 | Viewed by 3804
Abstract
Bio-based plastics made of food-safe compostable materials, such as thermoplastic starch (TPS), can be designed into films that have potential to replace many non-biodegradable single-use plastic (SUP) items. TPS film characteristics, such as elongation at break and tensile strength, are largely affected by [...] Read more.
Bio-based plastics made of food-safe compostable materials, such as thermoplastic starch (TPS), can be designed into films that have potential to replace many non-biodegradable single-use plastic (SUP) items. TPS film characteristics, such as elongation at break and tensile strength, are largely affected by the choice of the plasticizers used in formulation. Our work identifies the mechanical properties and the chemical structural differences between TPS films made with two different plasticizer mixtures that have not yet been compared alongside one another: deep eutectic solvent choline chloride/urea (1:2) (CC:U) and glycerol with an acetic acid catalyst (AA:G). Potato-based TPS samples were formed by mixing each plasticizer with a consistent amount of potato starch and distilled water with heat. After gelation formation, the viscous TPS mixture was centrifuged to degas and extruded. Films were dried at controlled room temperature. Characterization included the tensile testing of coupons according to ASTM (American Society of Testing and Materials) standard D638, attenuated total reflectance Fourier-transform infrared (ATR-FTIR) spectroscopy, X-ray diffraction (XRD), melting point (MP), and scanning electron microscopy (SEM). The AA:G films displayed significantly higher tensile strength (M = 2.04 ± 1.24 MPa) than the CC:U films (M = 0.18 ± 0.08 MPa); however, the CC:U films had higher elongation at break (M = 47.2 ± 3.6%) than the AA:G films (M = 31.1 ± 12.6%). This can be explained by the difference in functional groups, composition, and the degree of crystallinity evidenced by the FTIR, XRD, MP, and SEM results. Our findings suggest that potato-based TPS films with an AA:G plasticizer mixture hold promise for SUP applications that require more strength, while CC:U films may be more suited for wraps and bags that require flexibility. These innovations can aid to mitigate the environmental impact of harmful plastic waste. Full article
(This article belongs to the Special Issue Biomaterials and Biobased Polymers)
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14 pages, 10865 KB  
Article
Finite Element Analysis of Various Osteotomies Used in the Treatment of Developmental Hip Dysplasia in Children
by Zsuzsanna Incze-Bartha, Sandor Incze-Bartha, Zsuzsánna Simon-Szabó, Andrei Marian Feier, Vlad Vunvulea, Alin Ioan Nechifor-Boila, Ylenia Pastorello and Lorand Denes
J. Pers. Med. 2024, 14(2), 189; https://doi.org/10.3390/jpm14020189 - 8 Feb 2024
Cited by 5 | Viewed by 2264
Abstract
Late-discovered developmental hip dysplasia deformities often necessitate complex surgical treatments and meticulous preoperative planning. The selection of osteotomies is contingent upon the patient’s age and the specific structural deformity of the hip. In our anatomical hip model, derived from the data of a [...] Read more.
Late-discovered developmental hip dysplasia deformities often necessitate complex surgical treatments and meticulous preoperative planning. The selection of osteotomies is contingent upon the patient’s age and the specific structural deformity of the hip. In our anatomical hip model, derived from the data of a 12-year-old patient, we performed virtual osteotomies that are commonly recommended for such cases. We precisely constructed geometric models for various osteotomies, including the Dega, Pemberton, Tönnis, Ganz, Chiari pelvic, and Pauwels femoral osteotomies. We employed Autodesk Inventor for the finite element analysis of the hip joint and the corrective osteotomies. In comparing one-stage osteotomies, we noted that the Dega and Ganz pelvic osteotomies, especially when combined with the Pauwels femoral osteotomy, yielded the most favorable outcomes. These combinations led to enhanced femoral head coverage and reduced intra-articular pressure. Furthermore, we calculated the femoral head-to-acetabulum volume ratio for both the Dega and Pauwels osteotomies. The encouraging results we obtained advocate for the integration of finite element analysis in virtual osteotomies of the pelvis and femur as a preoperative tool in the management of developmental hip dysplasia. Full article
(This article belongs to the Special Issue Personalized Management in Orthopedics and Traumatology)
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13 pages, 640 KB  
Systematic Review
Postoperative Cast Immobilization Might Be Unnecessary after Pelvic Osteotomy for Children with Developmental Hip Dysplasia: A Systematic Review
by Mohamed Mai, Renée A. van Stralen, Sophie Moerman and Christiaan J. A. van Bergen
Surg. Tech. Dev. 2024, 13(1), 9-21; https://doi.org/10.3390/std13010002 - 15 Jan 2024
Cited by 1 | Viewed by 4779
Abstract
Background: Developmental dysplasia of the hip (DDH) is a common disorder of atypical hip development. Pelvic osteotomy (e.g., according to Salter, Pemberton or Dega) may be indicated for children with DDH at walking age. The most popular postoperative treatment is a hip spica [...] Read more.
Background: Developmental dysplasia of the hip (DDH) is a common disorder of atypical hip development. Pelvic osteotomy (e.g., according to Salter, Pemberton or Dega) may be indicated for children with DDH at walking age. The most popular postoperative treatment is a hip spica cast. Alternative postoperative options include abduction braces and non-weightbearing protocols combined with physical therapy. The aim of this systematic review was to determine the most effective form of postoperative treatment after unilateral pelvic osteotomy in children with DDH in terms of clinical and radiological outcomes and complications. Methods: A systematic review was conducted and reported according to Preferred Reporting Items for Systematic Reviews and Meta-Analysis 2020 guidelines and registered in the international prospective register of systematic reviews. Articles were selected from PubMed, Embase and Cochrane databases. The quality of all (non-)randomized included studies was assessed using the Methodological Index for Non-Randomized Studies (MINORS) criteria. Results: The search strategy yielded 3524 articles. Fourteen articles with 367 total hips were included in this review. A total of 312 hips were treated with spica casts, 49 with abduction braces and 6 with non-weightbearing protocols. The quality of evidence was moderate (MINORS, 3–12 points). All types of postoperative treatments had good clinical outcomes overall, without secondary displacement of the osteotomy. Clinical outcomes for spica casts were reported according to McKay’s criteria in 135 hips, with 123 excellent and 12 good results. Clinical outcomes for abduction braces showed satisfaction for all parents (49 of 49). The radiological outcome was overall well preserved with any postoperative treatment. There was a higher complication rate with the use of hip spica casts, including avascular necrosis, pain complaints and superficial infections. Conclusion: This systematic review showed no benefit of postoperative spica casts compared with abduction braces and avoidance of weightbearing after simple pelvic osteotomy for residual DDH. Full article
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9 pages, 285 KB  
Article
Tranexamic Acid in Hip Reconstructions in Children with Cerebral Palsy: A Double-Blind Randomized Controlled Clinical Trial
by Alexandre Zuccon, Paulo Rogério Cardozo Kanaji, Dávia Serafini Barcellos, Saulo Zabulon, Ageu de Oliveira Saraiva and Thaila Andressa Yoshi de Freitas
Children 2023, 10(12), 1931; https://doi.org/10.3390/children10121931 - 15 Dec 2023
Cited by 6 | Viewed by 2208
Abstract
Surgical treatment is indicated for hip dislocation in patients with cerebral palsy (CP), but it requires care due to the state of nutrition and associated clinical comorbidities. The use of resources that minimize blood loss and the need for blood transfusions are essential [...] Read more.
Surgical treatment is indicated for hip dislocation in patients with cerebral palsy (CP), but it requires care due to the state of nutrition and associated clinical comorbidities. The use of resources that minimize blood loss and the need for blood transfusions are essential to avoid complications. Tranexamic acid (TXA) has been highlighted for orthopedic surgeries to control intraoperative bleeding; however, there is a lack of large studies for its use in hip surgeries in patients with CP. This study aims to evaluate the efficacy and safety of tranexamic acid to reduce bleeding in pediatric patients with cerebral palsy undergoing surgical treatment for hip instability. A sample of 31 patients with CP who underwent surgical treatment for hip dislocation (hip adductor stretching, varization osteotomy of the proximal femur and acetabuloplasty using the Dega technique) was randomly divided into groups: control (n = 10) and TXA (n = 21). Preoperative and 24 h hemoglobin concentrations, the length of hospital stay (LHS), and intraoperative bleeding (IB) were analyzed. TXA significantly reduced the IB (p = 0.02). The variance in hemoglobin concentration was lower for the TXA group, but without statistical significance (p = 0.06). There was no difference in LHS. Also, no statistical difference was observed for the number of transfusions (p = 0.08). The findings provide evidence of the effectiveness of TXA in decreasing intraoperative bleeding and its safety for use in pediatric patients with cerebral palsy. Full article
(This article belongs to the Special Issue Research in Paediatric Orthopaedic Surgery)
17 pages, 2382 KB  
Article
Post-Mining Multi-Hazard Assessment for Sustainable Development
by Mohamed Marwan Al Heib, Christian Franck, Hippolyte Djizanne and Marie Degas
Sustainability 2023, 15(10), 8139; https://doi.org/10.3390/su15108139 - 17 May 2023
Cited by 17 | Viewed by 3850
Abstract
Today, most mines (coal, iron, and others) in Europe are already closed due to economic, environmental, and societal issues. Therefore, post-mining risk assessment and management remain crucial for mining authorities, policymakers, and planners. In the post-mining period, several hazards are likely to affect [...] Read more.
Today, most mines (coal, iron, and others) in Europe are already closed due to economic, environmental, and societal issues. Therefore, post-mining risk assessment and management remain crucial for mining authorities, policymakers, and planners. In the post-mining period, several hazards are likely to affect the surface areas in the closed mining sites. The impact of closed mines can lead to potentially damaging changes in surface and/or underground water flow, as well as the development of surface instabilities that can affect people or infrastructure, sometimes dangerously. The assessment of the different hazards must consider the interaction between the mining hazards and other risks (natural and technological). Thus, land use planning, particularly the rehabilitation of former mining sites, requires better tools to apprehend the multiplicity of hazards and their constraints. The paper presents a methodology considering the interactions between hazards around closed mines. After recalling the advantages of this multi-hazard analysis, the work consisted of, almost exhaustively, describing the three prominent families of hazards: mining, natural, and technological. Then, the possible interactions between hazards were described according to their nature (trigger or aggravating), their category (technical or regulatory), and their typology (dependent or independent). Finally, an attempt was proposed to evaluate the type and intensity of interactions between hazards. The multi-hazard assessment methodology was applied to a coal mine and showed the complexity and the utility of such a risk assessment analysis to improve risk management in closed mines. Full article
(This article belongs to the Special Issue Sustainable Mining and Processing of Mineral Resources)
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14 pages, 8016 KB  
Article
Surfactant-Free Decellularization of Porcine Auricular Cartilage Using Liquefied Dimethyl Ether and DNase
by Hideki Kanda, Kento Oya, Wahyudiono and Motonobu Goto
Materials 2023, 16(8), 3172; https://doi.org/10.3390/ma16083172 - 18 Apr 2023
Cited by 7 | Viewed by 3270
Abstract
The most common decellularization method involves lipid removal using surfactant sodium dodecyl sulfate (SDS) and DNA fragmentation using DNase, and is associated with residual SDS. We previously proposed a decellularization method for the porcine aorta and ostrich carotid artery using liquefied dimethyl ether [...] Read more.
The most common decellularization method involves lipid removal using surfactant sodium dodecyl sulfate (SDS) and DNA fragmentation using DNase, and is associated with residual SDS. We previously proposed a decellularization method for the porcine aorta and ostrich carotid artery using liquefied dimethyl ether (DME), which is free from the concerns associated with SDS residues, instead of SDS. In this study, the DME + DNase method was tested on crushed porcine auricular cartilage tissues. Unlike with the porcine aorta and the ostrich carotid artery, it is important to degas the porcine auricular cartilage using an aspirator before DNA fragmentation. Although approximately 90% of the lipids were removed using this method, approximately 2/3 of the water was removed, resulting in a temporary Schiff base reaction. The amount of residual DNA in the tissue was approximately 27 ng/mg dry weight, which is lower than the regulatory value of 50 ng/mg dry weight. Hematoxylin and eosin staining confirmed that cell nuclei were removed from the tissue. Residual DNA fragment length assessment by electrophoresis confirmed that the residual DNA was fragmented to less than 100 bp, which was lower than the regulatory limit of 200 bp. By contrast, in the uncrushed sample, only the surface was decellularized. Thus, although limited to a sample size of approximately 1 mm, liquefied DME can be used to decellularize porcine auricular cartilage. Thus, liquefied DME, with its low persistence and high lipid removal capacity, is an effective alternative to SDS. Full article
(This article belongs to the Special Issue Advance in Biomaterials for Tissue Engineering)
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19 pages, 3351 KB  
Article
A New Porous Nozzle for Aluminum Melts Purification—Preparation and Mathematical–Physical Model
by Yapeng Tan, Guoqing Zhang, Weihong Lu, Bo Yang, Zhichao Tang, Zhengbing Xu, Qinjia Zheng, Jianmin Zeng, Hongqun Tang, Junsheng Wang, Aoke Jiang and Lei Xiang
Metals 2023, 13(3), 586; https://doi.org/10.3390/met13030586 - 13 Mar 2023
Viewed by 2302
Abstract
Aluminum and its alloy castings are used more and more widely, and it is particularly important to remove impurities in the alloy. According to the principle of bubble floatation for degassing aluminum melt, a new porous nozzle with controllable pores was developed, and [...] Read more.
Aluminum and its alloy castings are used more and more widely, and it is particularly important to remove impurities in the alloy. According to the principle of bubble floatation for degassing aluminum melt, a new porous nozzle with controllable pores was developed, and a hydraulic simulation experimental device was studied with the nozzle. The effects of the particle size ratio of the coarse sand to fine sand and volume fraction of fine sand on the porosity of the porous nozzle were studied by orthogonal experiment, and permeability and compressive strength of the porous nozzle were used as test indicators to determine the optimal parameters of preparation for the porous nozzle. The optimal parameters are fine sand of 100 mesh, and fine sand of 50 wt.%, binder of 17.5 wt.%, pore-forming agent of 6 wt.%, and pressure of making sample of 5 MPa. The nozzle with optimal parameters was prepared and tested, and the permeability is 112.2 × 10−12 m2 and the compressive strength is 2.3 MPa. In addition, a physical model of gas transmission in the porous nozzle was proposed. With the increase in the proportion of fine sand, the permeability of the porous nozzle decreases, the compressive strength increases, and the calculated porosity increases. The hydraulic simulation of melt injection was carried out, and the mathematical model for calculating the bubble diameter of bubble floatation was formulated. The model shows that the bubble diameter increases with the increase in gas flow rate. The experiment shows that the prepared porous nozzle has the merits of a simple preparation process and low-cost, which is expected to degas aluminum melts. Full article
(This article belongs to the Section Computation and Simulation on Metals)
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14 pages, 2418 KB  
Article
Degassing a Decellularized Scaffold Enhances Wound Healing and Reduces Fibrosis during Tracheal Defect Reconstruction: A Preliminary Animal Study
by Nguyen-Kieu Viet-Nhi, Yen-Chun Chen, Luong Huu Dang, How Tseng and Shih-Han Hung
J. Funct. Biomater. 2023, 14(3), 147; https://doi.org/10.3390/jfb14030147 - 5 Mar 2023
Cited by 3 | Viewed by 3201
Abstract
Few efforts have been made regarding the optimization of porcine small intestinal submucosa (SIS) to improve its biocompatibility. This study aims to evaluate the effect of SIS degassing on the promotion of cell attachment and wound healing. The degassed SIS was evaluated in [...] Read more.
Few efforts have been made regarding the optimization of porcine small intestinal submucosa (SIS) to improve its biocompatibility. This study aims to evaluate the effect of SIS degassing on the promotion of cell attachment and wound healing. The degassed SIS was evaluated in vitro and in vivo, compared with the nondegassed SIS control. In the cell sheet reattachment model, the reattached cell sheet coverage was significantly higher in the degassed SIS group than in the nondegassed group. Cell sheet viability was also significantly higher in the SIS group than in the control group. In vivo studies showed that the tracheal defect repaired by the degassed SIS patch showed enhanced healing and reductions in fibrosis and luminal stenosis compared to the nondegassed SIS control group, with the thickness of the transplanted grafts in the degassed SIS group significantly lower than those in the control group (346.82 ± 28.02 µm vs. 771.29 ± 20.41 µm, p < 0.05). Degassing the SIS mesh significantly promoted cell sheet attachment and wound healing by reducing luminal fibrosis and stenosis compared to the nondegassed control SIS. The results suggest that the degassing processing might be a simple and effective way to improve the biocompatibility of SIS. Full article
(This article belongs to the Special Issue Applications of Biomaterials in Otorhinolaryngology)
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