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19 pages, 10554 KB  
Review
Unveiling Guyon’s Canal: Insights into Clinical Anatomy, Pathology, and Imaging
by Sonal Saran, Saavi Reddy Pellakuru, Kapil Shirodkar, Ankit B. Shah, Aakanksha Agarwal, Ankur Shah, Karthikeyan P. Iyengar and Rajesh Botchu
Diagnostics 2025, 15(5), 592; https://doi.org/10.3390/diagnostics15050592 - 28 Feb 2025
Cited by 1 | Viewed by 6515
Abstract
Guyon’s canal, or the ulnar tunnel, is a critical anatomical structure at the wrist that houses the ulnar nerve and artery, making it susceptible to various pathological conditions. Pathologies affecting this canal include traumatic injuries, compressive neuropathies like ulnar tunnel syndrome, and space-occupying [...] Read more.
Guyon’s canal, or the ulnar tunnel, is a critical anatomical structure at the wrist that houses the ulnar nerve and artery, making it susceptible to various pathological conditions. Pathologies affecting this canal include traumatic injuries, compressive neuropathies like ulnar tunnel syndrome, and space-occupying lesions such as ganglion cysts. Ulnar tunnel syndrome, characterised by numbness, tingling, and weakness in the ulnar nerve distribution, is a prevalent condition that can severely impair hand function. The canal’s intricate anatomy is defined by surrounding ligaments and bones, divided into three zones, each containing distinct neural structures. Variations, including aberrant muscles and vascular anomalies, can complicate diagnosis and treatment. Imaging techniques are essential for evaluating these conditions; ultrasound provides real-time, dynamic assessments, while magnetic resonance imaging (MRI) offers detailed visualisation of soft tissues and bony structures, aiding in pre-surgical documentation and pathology evaluation. This review article explores the anatomy, pathologies, and imaging modalities associated with Guyon’s canal and underscores the necessity of understanding Guyon’s canal’s anatomy and associated pathologies to improve diagnostic accuracy and management strategies. By integrating anatomical insights with advanced imaging techniques, clinicians can enhance patient outcomes and preserve hand function, emphasising the need for increased awareness and research in this often-neglected area of hand anatomy. Full article
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34 pages, 29605 KB  
Review
Imaging of Peripheral Intraneural Tumors: A Comprehensive Review for Radiologists
by Kapil Shirodkar, Mohsin Hussein, Pellakuru Saavi Reddy, Ankit B. Shah, Sameer Raniga, Devpriyo Pal, Karthikeyan P. Iyengar and Rajesh Botchu
Cancers 2025, 17(2), 246; https://doi.org/10.3390/cancers17020246 - 13 Jan 2025
Cited by 2 | Viewed by 4466
Abstract
Background/Objectives: Intraneural tumors (INTs) pose a diagnostic challenge, owing to their varied origins within nerve fascicles and their wide spectrum, which includes both benign and malignant forms. Accurate diagnosis and management of these tumors depends upon the skills of the radiologist in identifying [...] Read more.
Background/Objectives: Intraneural tumors (INTs) pose a diagnostic challenge, owing to their varied origins within nerve fascicles and their wide spectrum, which includes both benign and malignant forms. Accurate diagnosis and management of these tumors depends upon the skills of the radiologist in identifying key imaging features and correlating them with the patient’s clinical symptoms and examination findings. Methods: This comprehensive review systematically analyzes the various imaging features in the diagnosis of intraneural tumors, ranging from basic MR to advanced MR imaging techniques such as MR neurography (MRN), diffusion tensor imaging (DTI), and dynamic contrast-enhanced (DCE) MRI. Results: The article emphasizes the differentiation of benign from malignant lesions using characteristic MRI features, such as the “target sign” and “split-fat sign” for tumor characterization. The role of advanced multiparametric MRI in improving biopsy planning, guiding surgical mapping, and enhancing post-treatment monitoring is also highlighted. The review also underlines the importance of common diagnostic pitfalls and highlights the need for a multi-disciplinary approach to achieve an accurate diagnosis, appropriate treatment strategy, and post-therapy surveillance planning. Conclusions: In this review, we illustrate the main imaging findings of intraneural tumors, focusing on specific MR imaging features that are crucial for an accurate diagnosis and the differentiation between benign and malignant lesions. Full article
(This article belongs to the Section Methods and Technologies Development)
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15 pages, 1293 KB  
Article
COVID-19 Data Analysis with a Multi-Objective Evolutionary Algorithm for Causal Association Rule Mining
by Santiago Sinisterra-Sierra, Salvador Godoy-Calderón and Miriam Pescador-Rojas
Math. Comput. Appl. 2023, 28(1), 12; https://doi.org/10.3390/mca28010012 - 13 Jan 2023
Cited by 2 | Viewed by 3135
Abstract
Association rule mining plays a crucial role in the medical area in discovering interesting relationships among the attributes of a data set. Traditional association rule mining algorithms such as Apriori, FP growth, or Eclat require considerable computational resources and generate large volumes [...] Read more.
Association rule mining plays a crucial role in the medical area in discovering interesting relationships among the attributes of a data set. Traditional association rule mining algorithms such as Apriori, FP growth, or Eclat require considerable computational resources and generate large volumes of rules. Moreover, these techniques depend on user-defined thresholds which can inadvertently cause the algorithm to omit some interesting rules. In order to solve such challenges, we propose an evolutionary multi-objective algorithm based on NSGA-II to guide the mining process in a data set composed of 15.5 million records with official data describing the COVID-19 pandemic in Mexico. We tested different scenarios optimizing classical and causal estimation measures in four waves, defined as the periods of time where the number of people with COVID-19 increased. The proposed contributions generate, recombine, and evaluate patterns, focusing on recovering promising high-quality rules with actionable cause–effect relationships among the attributes to identify which groups are more susceptible to disease or what combinations of conditions are necessary to receive certain types of medical care. Full article
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10 pages, 256 KB  
Article
Smoking Addiction in Patients with Schizophrenia Spectrum Disorders and Its Perception and Intervention in Healthcare Personnel Assigned to Psycho-Rehabilitation Programs: A Qualitative Research
by Pasquale Caponnetto, Marilena Maglia, Marta Mangione, Chiara Vergopia, Graziella Chiara Prezzavento, Riccardo Polosa, Maria Catena Quattropani, Jennifer DiPiazza and Maria Salvina Signorelli
Healthcare 2022, 10(11), 2275; https://doi.org/10.3390/healthcare10112275 - 13 Nov 2022
Cited by 2 | Viewed by 3783
Abstract
Patients with schizophrenia spectrum disorders have a higher prevalence and frequency of smoking rates when compared to the rest of the population; to this, it must be added that they develop a greater dependence and have some worse health consequences than the general [...] Read more.
Patients with schizophrenia spectrum disorders have a higher prevalence and frequency of smoking rates when compared to the rest of the population; to this, it must be added that they develop a greater dependence and have some worse health consequences than the general population. This is qualitative research on the perception of smoking in healthcare professionals assigned to psycho-rehabilitation programs for patients with schizophrenia spectrum disorders. The point of view of health personnel (Psychologists, Psychiatrists, Pedagogists, and Nurses) about cigarette smoking in these patients was analyzed, focusing on their implications in disturbance and comparing them with e-cigarettes too. The methodology used to collect the data was a semi-structured interview with five questions. The research path was carried out in two assisted therapeutic communities that are clinics for the rehabilitation of serious mental illness in the period between November and July 2022. The results showed that the opinion of health professionals on smoking is very negative. Research has also shown that nearly all patients are smokers; however, their high grade of addiction is caused by periods of high stress due to various factors that lead patients to consume a greater number of cigarettes. Almost all respondents have a positive opinion of the e-cigarette, which was defined as an excellent substitute for traditional cigarettes. Full article
(This article belongs to the Special Issue Present and Future Challenges in Tobacco Control)
28 pages, 3344 KB  
Article
Visual Analytics for Predicting Disease Outcomes Using Laboratory Test Results
by Neda Rostamzadeh, Sheikh S. Abdullah, Kamran Sedig, Amit X. Garg and Eric McArthur
Informatics 2022, 9(1), 17; https://doi.org/10.3390/informatics9010017 - 25 Feb 2022
Cited by 2 | Viewed by 5081
Abstract
Laboratory tests play an essential role in the early and accurate diagnosis of diseases. In this paper, we propose SUNRISE, a visual analytics system that allows the user to interactively explore the relationships between laboratory test results and a disease outcome. SUNRISE integrates [...] Read more.
Laboratory tests play an essential role in the early and accurate diagnosis of diseases. In this paper, we propose SUNRISE, a visual analytics system that allows the user to interactively explore the relationships between laboratory test results and a disease outcome. SUNRISE integrates frequent itemset mining (i.e., Eclat algorithm) with extreme gradient boosting (XGBoost) to develop more specialized and accurate prediction models. It also includes interactive visualizations to allow the user to interact with the model and track the decision process. SUNRISE helps the user probe the prediction model by generating input examples and observing how the model responds. Furthermore, it improves the user’s confidence in the generated predictions and provides them the means to validate the model’s response by illustrating the underlying working mechanism of the prediction models through visualization representations. SUNRISE offers a balanced distribution of processing load through the seamless integration of analytical methods with interactive visual representations to support the user’s cognitive tasks. We demonstrate the usefulness of SUNRISE through a usage scenario of exploring the association between laboratory test results and acute kidney injury, using large provincial healthcare databases from Ontario, Canada. Full article
(This article belongs to the Special Issue Feature Papers: Health Informatics)
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15 pages, 3862 KB  
Article
Research on Frequent Itemset Mining of Imaging Genetics GWAS in Alzheimer’s Disease
by Hong Liang, Luolong Cao, Yue Gao, Haoran Luo, Xianglian Meng, Ying Wang, Jin Li and Wenjie Liu
Genes 2022, 13(2), 176; https://doi.org/10.3390/genes13020176 - 19 Jan 2022
Cited by 1 | Viewed by 2967
Abstract
As an efficient method, genome-wide association study (GWAS) is used to identify the association between genetic variation and pathological phenotypes, and many significant genetic variations founded by GWAS are closely associated with human diseases. However, it is not enough to mine only a [...] Read more.
As an efficient method, genome-wide association study (GWAS) is used to identify the association between genetic variation and pathological phenotypes, and many significant genetic variations founded by GWAS are closely associated with human diseases. However, it is not enough to mine only a single marker effect variation on complex biological phenotypes. Mining highly correlated single nucleotide polymorphisms (SNP) is more meaningful for the study of Alzheimer's disease (AD). In this paper, we used two frequent pattern mining (FPM) framework, the FP-Growth and Eclat algorithms, to analyze the GWAS results of functional magnetic resonance imaging (fMRI) phenotypes. Moreover, we applied the definition of confidence to FP-Growth and Eclat to enhance the FPM framework. By calculating the conditional probability of identified SNPs, we obtained the corresponding association rules to provide support confidence between these important SNPs. The resulting SNPs showed close correlation with hippocampus, memory, and AD. The experimental results also demonstrate that our framework is effective in identifying SNPs and provide candidate SNPs for further research. Full article
(This article belongs to the Section Human Genomics and Genetic Diseases)
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22 pages, 6057 KB  
Article
An Efficient Spark-Based Hybrid Frequent Itemset Mining Algorithm for Big Data
by Mohamed Reda Al-Bana, Marwa Salah Farhan and Nermin Abdelhakim Othman
Data 2022, 7(1), 11; https://doi.org/10.3390/data7010011 - 14 Jan 2022
Cited by 20 | Viewed by 8460
Abstract
Frequent itemset mining (FIM) is a common approach for discovering hidden frequent patterns from transactional databases used in prediction, association rules, classification, etc. Apriori is an FIM elementary algorithm with iterative nature used to find the frequent itemsets. Apriori is used to scan [...] Read more.
Frequent itemset mining (FIM) is a common approach for discovering hidden frequent patterns from transactional databases used in prediction, association rules, classification, etc. Apriori is an FIM elementary algorithm with iterative nature used to find the frequent itemsets. Apriori is used to scan the dataset multiple times to generate big frequent itemsets with different cardinalities. Apriori performance descends when data gets bigger due to the multiple dataset scan to extract the frequent itemsets. Eclat is a scalable version of the Apriori algorithm that utilizes a vertical layout. The vertical layout has many advantages; it helps to solve the problem of multiple datasets scanning and has information that helps to find each itemset support. In a vertical layout, itemset support can be achieved by intersecting transaction ids (tidset/tids) and pruning irrelevant itemsets. However, when tids become too big for memory, it affects algorithms efficiency. In this paper, we introduce SHFIM (spark-based hybrid frequent itemset mining), which is a three-phase algorithm that utilizes both horizontal and vertical layout diffset instead of tidset to keep track of the differences between transaction ids rather than the intersections. Moreover, some improvements are developed to decrease the number of candidate itemsets. SHFIM is implemented and tested over the Spark framework, which utilizes the RDD (resilient distributed datasets) concept and in-memory processing that tackles MapReduce framework problem. We compared the SHFIM performance with Spark-based Eclat and dEclat algorithms for the four benchmark datasets. Experimental results proved that SHFIM outperforms Eclat and dEclat Spark-based algorithms in both dense and sparse datasets in terms of execution time. Full article
(This article belongs to the Special Issue Knowledge Extraction from Data Using Machine Learning)
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20 pages, 2117 KB  
Article
Efficient Discovery of Periodic-Frequent Patterns in Columnar Temporal Databases
by Penugonda Ravikumar, Palla Likhitha, Bathala Venus Vikranth Raj, Rage Uday Kiran, Yutaka Watanobe and Koji Zettsu
Electronics 2021, 10(12), 1478; https://doi.org/10.3390/electronics10121478 - 19 Jun 2021
Cited by 18 | Viewed by 3249
Abstract
Discovering periodic-frequent patterns in temporal databases is a challenging problem of great importance in many real-world applications. Though several algorithms were described in the literature to tackle the problem of periodic-frequent pattern mining, most of these algorithms use the traditional horizontal (or row) [...] Read more.
Discovering periodic-frequent patterns in temporal databases is a challenging problem of great importance in many real-world applications. Though several algorithms were described in the literature to tackle the problem of periodic-frequent pattern mining, most of these algorithms use the traditional horizontal (or row) database layout, that is, either they need to scan the database several times or do not allow asynchronous computation of periodic-frequent patterns. As a result, this kind of database layout makes the algorithms for discovering periodic-frequent patterns both time and memory inefficient. One cannot ignore the importance of mining the data stored in a vertical (or columnar) database layout. It is because real-world big data is widely stored in columnar database layout. With this motivation, this paper proposes an efficient algorithm, Periodic Frequent-Equivalence CLass Transformation (PF-ECLAT), to find periodic-frequent patterns in a columnar temporal database. Experimental results on sparse and dense real-world and synthetic databases demonstrate that PF-ECLAT is memory and runtime efficient and highly scalable. Finally, we demonstrate the usefulness of PF-ECLAT with two case studies. In the first case study, we have employed our algorithm to identify the geographical areas in which people were periodically exposed to harmful levels of air pollution in Japan. In the second case study, we have utilized our algorithm to discover the set of road segments in which congestion was regularly observed in a transportation network. Full article
(This article belongs to the Special Issue Spatiotemporal Big Data Analytics)
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14 pages, 2017 KB  
Article
A Fault Analysis Method Based on Association Rule Mining for Distribution Terminal Unit
by Xuecen Zhang, Yi Tang, Qiang Liu, Guofeng Liu, Xin Ning and Jiankun Chen
Appl. Sci. 2021, 11(11), 5221; https://doi.org/10.3390/app11115221 - 4 Jun 2021
Cited by 15 | Viewed by 3119
Abstract
With the development of distribution networks, large amounts of distribution terminal units (DTU) are gradually integrated into the power system. However, limited numbers of maintenance engineers can hardly cope with the pressure brought about by the substantial increase of DTU devices. As DTU [...] Read more.
With the development of distribution networks, large amounts of distribution terminal units (DTU) are gradually integrated into the power system. However, limited numbers of maintenance engineers can hardly cope with the pressure brought about by the substantial increase of DTU devices. As DTU fault would pose a threat to the stable and safe operation of power systems; thus, it is rather significant to reduce the fault incidence of DTU devices and improve the efficiency of fault elimination. In this paper, a DTU fault analysis method using an association rule mining algorithm was proposed. Key factors of DTU fault were analyzed at first. Then, the main concept of the Eclat algorithm was illustrated, and its performance was compared with FP-growth and Apriori algorithms using DTU fault databases of different sizes. Afterwards, a DTU fault analysis method based on the Eclat algorithm was proposed. The practicality of this method was proven by experiment using a realistic DTU fault database. Finally, the application of this method was presented to demonstrate its effectiveness. Full article
(This article belongs to the Special Issue Electric Power Applications)
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15 pages, 1154 KB  
Article
An Improved Eclat Algorithm Based on Tissue-Like P System with Active Membranes
by Linlin Jia, Laisheng Xiang and Xiyu Liu
Processes 2019, 7(9), 555; https://doi.org/10.3390/pr7090555 - 22 Aug 2019
Cited by 8 | Viewed by 3934
Abstract
The Eclat algorithm is a typical frequent pattern mining algorithm using vertical data. This study proposes an improved Eclat algorithm called ETPAM, based on the tissue-like P system with active membranes. The active membranes are used to run evolution rules, i.e., object rewriting [...] Read more.
The Eclat algorithm is a typical frequent pattern mining algorithm using vertical data. This study proposes an improved Eclat algorithm called ETPAM, based on the tissue-like P system with active membranes. The active membranes are used to run evolution rules, i.e., object rewriting rules, in parallel. Moreover, ETPAM utilizes subsume indices and an early pruning strategy to reduce the number of frequent pattern candidates and subsumes. The time complexity of ETPAM is decreased from O(t2) to O(t) as compared with the original Eclat algorithm through the parallelism of the P system. The experimental results using two databases indicate that ETPAM performs very well in mining frequent patterns, and the experimental results using four databases prove that ETPAM is computationally very efficient as compared with three other existing frequent pattern mining algorithms. Full article
(This article belongs to the Section Process Control and Monitoring)
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