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16 Results Found

  • Article
  • Open Access
4 Citations
2,319 Views
7 Pages

23 June 2022

Cardiovascular surgery is highly invasive, with a risk of postoperative coagulopathy due to various factors such as bleeding. Coagulopathy can progress to disseminated intravascular coagulation (DIC), which complicates various clinical conditions. Ho...

  • Article
  • Open Access
7 Citations
3,796 Views
9 Pages

Proposal of Quick Diagnostic Criteria for Disseminated Intravascular Coagulation

  • Hideo Wada,
  • Akitaka Yamamoto,
  • Masaki Tomida,
  • Yuhuko Ichikawa,
  • Minoru Ezaki,
  • Jun Masuda,
  • Masamichi Yoshida,
  • Shunsuke Fukui,
  • Isao Moritani and
  • Hideto Shimpo
  • + 5 authors

16 February 2022

Background. The diagnostic criteria for disseminated intravascular coagulation (DIC) vary and are complicated and the cut-off values are different. Simple and quick diagnostic criteria for DIC are required in physicians for critical care. Material an...

  • Article
  • Open Access
19 Citations
3,032 Views
7 Pages

Soluble C-Type Lectin-Like Receptor 2 Is a Biomarker for Disseminated Intravascular Coagulation

  • Akitaka Yamamoto,
  • Hideo Wada,
  • Yuhuko Ichkawa,
  • Motoko Tanaka,
  • Haruhiko Tashiro,
  • Katsuya Shiraki,
  • Hideto Shimpo,
  • Yoshiki Yamashita,
  • Takeshi Mastumoto and
  • Katsue Suzuki-Inoue
  • + 2 authors

28 June 2021

Disseminated intravascular coagulation (DIC) is induced by excess activation coagulation, and activated platelets are also involved in pathogenesis. Therefore, plasma levels of soluble C-type lectin-like receptor 2 (sCLEC-2), a new marker for platele...

  • Article
  • Open Access
18 Citations
3,320 Views
12 Pages

27 September 2019

Disseminated intravascular coagulation (DIC) is a catastrophic systemic disorder of coagulation, resulting in uncontrollable bleeding, multiple organ failure, and death. Sepsis is one of the common causes of DIC. Despite many attempts to correct thes...

  • Article
  • Open Access
8 Citations
2,702 Views
14 Pages

Super Formula for Diagnosing Disseminated Intravascular Coagulation Using Soluble C-Type Lectin-like Receptor 2

  • Akitaka Yamamoto,
  • Hideo Wada,
  • Masaki Tomida,
  • Yuhuko Ichikawa,
  • Minoru Ezaki,
  • Katsuya Shiraki,
  • Motomu Shimaoka,
  • Toshiaki Iba,
  • Katsue Suzuki-Inoue and
  • Hideto Shimpo
  • + 1 author

The scoring systems for disseminated intravascular coagulation (DIC) criteria require several adequate cutoff values, vary, and are complicated. Accordingly, a simpler and quicker diagnostic method for DIC is needed. Under such circumstances, soluble...

  • Article
  • Open Access
2 Citations
2,483 Views
19 Pages

2 October 2024

Background: Disseminated intravascular coagulation (DIC) is a severe condition affecting the coagulation system. However, current knowledge regarding its incidence and mortality remains limited. In this study, we examined the incidence and mortality...

  • Article
  • Open Access
19 Citations
6,337 Views
23 Pages

23 February 2022

Open innovation has drawn significant attention over the years, and there is a growing body of literature that highlights the importance of considering this phenomenon at the national level. Less appreciated, however, is the radiative capability of n...

  • Article
  • Open Access
6 Citations
2,853 Views
11 Pages

Clinical Outcomes of Early Endoscopic Transpapillary Biliary Drainage for Acute Cholangitis Associated with Disseminated Intravascular Coagulation

  • Akihiro Sekine,
  • Kazunari Nakahara,
  • Junya Sato,
  • Yosuke Michikawa,
  • Keigo Suetani,
  • Ryo Morita,
  • Yosuke Igarashi and
  • Fumio Itoh

16 August 2021

Acute cholangitis (AC) is often associated with disseminated intravascular coagulation (DIC), and endoscopic transpapillary biliary drainage (EBD) under endoscopic retrograde cholangiopancreatography (ERCP) is a treatment of choice. However, no evide...

  • Article
  • Open Access
3 Citations
2,929 Views
14 Pages

Agents that build interactive relationships with people can provide appropriate support and generate behaviors by accurately grasping the state of the person. This study focuses on the quality of life (QOL), which can be assessed multidimensionally,...

  • Review
  • Open Access
371 Views
14 Pages

Recognizing Coagulation Disorders in Sepsis in the Emergency Room: A Narrative Review

  • Toshiaki Iba,
  • Tomoki Tanigawa,
  • Hideo Wada,
  • Kenta Kondo,
  • Ricard Ferrer and
  • Jerrold H. Levy

8 January 2026

Sepsis remains a leading cause of global mortality, and early management in the emergency department (ED) is a key determinant of clinical outcomes. Among the earliest physiological derangements in sepsis are abnormalities in coagulation, which repre...

  • Article
  • Open Access
2 Citations
3,407 Views
18 Pages

Hematopathological Patterns in Acute Myeloid Leukemia with Complications of Overt Disseminated Intravascular Coagulation

  • Bernhard Strasser,
  • Sebastian Mustafa,
  • Josef Seier,
  • Josef Tomasits and
  • Alexander Haushofer

Background: Acute myeloid leukemia (AML) complicated by disseminated intravascular coagulation (DIC) poses major diagnostic and therapeutic challenges. While DIC is well documented in acute promyelocytic leukemia, its manifestations in non-APL AML re...

  • Article
  • Open Access
14 Citations
5,569 Views
24 Pages

7 October 2021

A non-destructive method using machine vision is an effective way to monitor plant growth. However, due to the lighting changes and complicated backgrounds in outdoor environments, this becomes a challenging task. In this paper, a low-cost camera sys...

  • Article
  • Open Access
37 Citations
5,131 Views
15 Pages

Serum Concentrations of Angiopoietin-2 and Soluble fms-Like Tyrosine Kinase 1 (sFlt-1) Are Associated with Coagulopathy among Patients with Acute Pancreatitis

  • Paulina Dumnicka,
  • Beata Kuśnierz-Cabala,
  • Mateusz Sporek,
  • Małgorzata Mazur-Laskowska,
  • Krzysztof Gil,
  • Marek Kuźniewski,
  • Piotr Ceranowicz,
  • Zygmunt Warzecha,
  • Artur Dembiński and
  • Ryszard Drożdż
  • + 1 author

In severe acute pancreatitis (SAP), systemic inflammation leads to endothelial dysfunction and activation of coagulation. Thrombotic disorders in acute pancreatitis (AP) include disseminated intravascular coagulation (DIC). Recently, angiopoietin-2 a...

  • Review
  • Open Access
1,533 Views
12 Pages

The Role of Inflammasomes in LPS and Gram-Negative Bacterial Sepsis

  • Eduardo Hernández-Cuellar,
  • Kohsuke Tsuchiya,
  • Oscar Medina-Contreras and
  • Ricardo Valle-Ríos

9 October 2025

Background/Objectives: Sepsis is a life-threatening condition characterized by an uncontrolled immune response due to systemic infections. It is responsible for millions of deaths worldwide. Although inflammasomes play an important role in host defen...

  • Article
  • Open Access
7 Citations
4,056 Views
16 Pages

Is There a Difference in the Utilisation of Inpatient Services Between Two Typical Payment Methods of Health Insurance? Evidence from the New Rural Cooperative Medical Scheme in China

  • Dai Su,
  • Yingchun Chen,
  • Hongxia Gao,
  • Haomiao Li,
  • Jingjing Chang,
  • Shihan Lei,
  • Di Jiang,
  • Xiaomei Hu,
  • Min Tan and
  • Zhifang Chen

This study aimed to evaluate the effects of the differences between two typical payment methods for the new rural cooperative medical scheme (NRCMS) in China on the utilisation of inpatient services. Interrupted time-series analysis (ITSA) and propen...

  • Review
  • Open Access
12 Citations
9,133 Views
13 Pages

12 January 2023

One of the ‘organs’ that can be affected by sepsis is the coagulation system. Coagulopathy in sepsis may take the form of sepsis-induced coagulopathy (SIC) or sepsis-associated disseminated intravascular coagulation (DIC). It is important...